Assessment of the red cell proteome of young patients with unexplained hemolytic anemia by two-dimensional differential in-gel electrophoresis (DIGE)

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  von Löhneysen, Katharina ^a   Scott, Thomas M ^a   Soldau, Katrin ^a   Xu, Xiuling ^a   Friedman, Jeffrey S ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; CYTOSKELETON PROTEIN; PROTEASOME; PROTEOME;

ADOLESCENT; ARTICLE; BLOOD TRANSFUSION; BONE MARROW BIOPSY; CASE REPORT; CHILD; CONTROLLED STUDY; DISEASE SEVERITY; ERYTHROCYTE; FEMALE; HEREDITARY HEMOLYTIC ANEMIA; HUMAN; HUMAN CELL; INFANT; MALE; MITOCHONDRIAL RESPIRATION; NUCLEOTIDE METABOLISM; PATHOGENESIS; PRESCHOOL CHILD; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; PROTEOMICS; RELATIVE; RETICULOCYTE COUNT; SCHOOL CHILD; SIGNAL TRANSDUCTION; TWO DIMENSIONAL DIFFERENCE GEL ELECTROPHORESIS; BLOOD; HEMOLYTIC ANEMIA; METABOLISM; METHODOLOGY; PRINCIPAL COMPONENT ANALYSIS; QUALITY CONTROL;

ADOLESCENT; ANEMIA, HEMOLYTIC; CHILD; CHILD, PRESCHOOL; ERYTHROCYTES; FEMALE; HUMANS; MALE; PRINCIPAL COMPONENT ANALYSIS; PROTEOMICS; QUALITY CONTROL; TWO-DIMENSIONAL DIFFERENCE GEL ELECTROPHORESIS;

EID: 84859237257     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0034237     Document Type: Article

References (68)

1. Hoffbrand AV, Moss PAH, Pettit JE, (2011) Essential haematology. Malden, Mass.: Wiley-Blackwell. xi, 454.
2. Koury MJ, Koury ST, Kopsombut P, Bondurant MC, (2005) In vitro maturation of nascent reticulocytes to erythrocytes. Blood 105: 2168-2174.
3. Sivilotti ML, (2004) Oxidant stress and haemolysis of the human erythrocyte. Toxicol Rev 23: 169-188.
4. Banerjee T, Kuypers FA, (2004) Reactive oxygen species and phosphatidylserine externalization in murine sickle red cells. Br J Haematol 124: 391-402.
5. Origa R, Galanello R, (2011) Pathophysiology of beta thalassaemia. Pediatr Endocrinol Rev 8 (Suppl 2): 263-270.
6. Fibach E, Rachmilewitz E, (2008) The role of oxidative stress in hemolytic anemia. Curr Mol Med 8: 609-619.
7. David O, Sacchetti L, Vota MG, Comino L, Perugini L, et al. (1990) Pyrimidine 5'-nucleotidase and oxidative damage in red blood cells transfused to beta-thalassemic children. Haematologica 75: 313-318.
8. Baronciani L, Bianchi P, Zanella A, (1996) Hematologically important mutations: red cell pyruvate kinase (1st update). Blood Cells Mol Dis 22: 259-264.
9. Prchal JT, Pastore YD, (2004) Erythropoietin and erythropoiesis: polycythemias due to disruption of oxygen homeostasis. Hematol J 5 (Suppl 3): S110-113.
10. Beutler E, Lichtman MA, Beutler E, Kipps TJ, Seligsohn U, et al. (2006) Disorders of red cells resulting from enzyme abnormalities. Williams Hematology. New York McGraw-Hill pp. 603-631.
11. Miwa S, Fujii H, (1996) Molecular basis of erythroenzymopathies associated with hereditary hemolytic anemia: tabulation of mutant enzymes. Am J Hematol 51: 122-132.
12. Kanno H, Ballas SK, Miwa S, Fujii H, Bowman HS, (1994) Molecular abnormality of erythrocyte pyruvate kinase deficiency in the Amish. Blood 83: 2311-2316.
13. Bouyssie D, Gonzalez de Peredo A, Mouton E, Albigot R, Roussel L, et al. (2007) Mascot file parsing and quantification (MFPaQ), a new software to parse, validate, and quantify proteomics data generated by ICAT and SILAC mass spectrometric analyses: application to the proteomics study of membrane proteins from primary human endothelial cells. Mol Cell Proteomics 6: 1621-1637.
14. Goodman SR, Kurdia A, Ammann L, Kakhniashvili D, Daescu O, (2007) The human red blood cell proteome and interactome. Exp Biol Med (Maywood) 232: 1391-1408.
15. Pasini EM, Kirkegaard M, Mortensen P, Lutz HU, Thomas AW, et al. (2006) In-depth analysis of the membrane and cytosolic proteome of red blood cells. Blood 108: 791-801.
16. Mingot JM, Bohnsack MT, Jakle U, Gorlich D, (2004) Exportin 7 defines a novel general nuclear export pathway. EMBO J 23: 3227-3236.
17. Markert ML, (1991) Purine nucleoside phosphorylase deficiency. Immunodefic Rev 3: 45-81.
18. Markert ML, Finkel BD, McLaughlin TM, Watson TJ, Collard HR, et al. (1997) Mutations in purine nucleoside phosphorylase deficiency. Hum Mutat 9: 118-121.
19. Clarkson YL, Gillespie T, Perkins EM, Lyndon AR, Jackson M, (2010) Beta-III spectrin mutation L253P associated with spinocerebellar ataxia type 5 interferes with binding to Arp1 and protein trafficking from the Golgi. Hum Mol Genet 19: 3634-3641.
20. Teumer A, Rawal R, Homuth G, Ernst F, Heier M, et al. (2011) Genome-wide association study identifies four genetic loci associated with thyroid volume and goiter risk. Am J Hum Genet 88: 664-673.
21. Kaibuchi K, Kuroda S, Amano M, (1999) Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells. Annu Rev Biochem 68: 459-486.
22. Stenmark H, (2009) Rab GTPases as coordinators of vesicle traffic. Nat Rev Mol Cell Biol 10: 513-525.
23. Squatrito M, Mancino M, Donzelli M, Areces LB, Draetta GF, (2004) EBP1 is a nucleolar growth-regulating protein that is part of pre-ribosomal ribonucleoprotein complexes. Oncogene 23: 4454-4465.
24. Zhang Y, Ali TZ, Zhou H, D'Souza DR, Lu Y, et al. (2010) ErbB3 binding protein 1 represses metastasis-promoting gene anterior gradient protein 2 in prostate cancer. Cancer Res 70: 240-248.
25. Hamburger AW, (2008) The role of ErbB3 and its binding partners in breast cancer progression and resistance to hormone and tyrosine kinase directed therapies. J Mammary Gland Biol Neoplasia 13: 225-233.
26. Andersen KM, Madsen L, Prag S, Johnsen AH, Semple CA, et al. (2009) Thioredoxin Txnl1/TRP32 is a redox-active cofactor of the 26 S proteasome. J Biol Chem 284: 15246-15254.
27. Hirono A, Iyori H, Sekine I, Ueyama J, Chiba H, et al. (1996) Three cases of hereditary nonspherocytic hemolytic anemia associated with red blood cell glutathione deficiency. Blood 87: 2071-2074.
28. Karp NA, Kreil DP, Lilley KS, (2004) Determining a significant change in protein expression with DeCyder during a pair-wise comparison using two-dimensional difference gel electrophoresis. Proteomics 4: 1421-1432.
29. Karp NA, Lilley KS, (2005) Maximising sensitivity for detecting changes in protein expression: experimental design using minimal CyDyes. Proteomics 5: 3105-3115.
30. Gilligan DM, Finney GL, Rynes E, Maccoss MJ, Lambert AJ, et al. (2011) Comparative proteomics reveals deficiency of NHE-1 (Slc9a1) in RBCs from the beta-adducin knockout mouse model of hemolytic anemia. Blood Cells Mol Dis 47: 85-94.
31. Radoshevich L, Debnath J, (2011) ATG12-ATG3 and mitochondria. Autophagy 7: 109-111.
32. Chen X, Sullivan DS, Huffaker TC, (1994) Two yeast genes with similarity to TCP-1 are required for microtubule and actin function in vivo. Proc Natl Acad Sci U S A 91: 9111-9115.
33. Yaffe MB, Farr GW, Miklos D, Horwich AL, Sternlicht ML, et al. (1992) TCP1 complex is a molecular chaperone in tubulin biogenesis. Nature 358: 245-248.
34. Hattangadi S, Burke K, Eng J, Cooney JD, Wang J, et al. (2011) Exportin 7 (RanBP16) Plays An Essential Role in Terminal Erythroid Chromatin Condensation and Enucleation. ASH Annual Meeting Abstracts 118 178-.
35. Malygin AA, Babaylova ES, Loktev VB, Karpova GG, (2011) A region in the C-terminal domain of ribosomal protein SA required for binding of SA to the human 40S ribosomal subunit. Biochimie 93: 612-617.
36. Nelson J, McFerran NV, Pivato G, Chambers E, Doherty C, et al. (2008) The 67 kDa laminin receptor: structure, function and role in disease. Biosci Rep 28: 33-48.
37. Sharma SK, Christen P, Goloubinoff P, (2009) Disaggregating chaperones: an unfolding story. Curr Protein Pept Sci 10: 432-446.
38. Khalil AA, Kabapy NF, Deraz SF, Smith C, (2011) Heat shock proteins in oncology: Diagnostic biomarkers or therapeutic targets? Biochim Biophys Acta 1816 89-104 pp. 89-104.
39. Pratt WB, Morishima Y, Peng HM, Osawa Y, (2010) Proposal for a role of the Hsp90/Hsp70-based chaperone machinery in making triage decisions when proteins undergo oxidative and toxic damage. Exp Biol Med (Maywood) 235: 278-289.
40. Ghosh N, Ghosh R, Mandal SC, (2011) Antioxidant protection: A promising therapeutic intervention in neurodegenerative disease. Free Radic Res 45: 888-905.
41. Patterson ST, Li J, Kang JA, Wickrema A, Williams DB, et al. (2009) Loss of specific chaperones involved in membrane glycoprotein biosynthesis during the maturation of human erythroid progenitor cells. J Biol Chem 284: 14547-14557.
42. Bhattacharya D, Saha S, Basu S, Chakravarty S, Chakravarty A, et al. (2010) Differential regulation of redox proteins and chaperones in HbEbeta-thalassemia erythrocyte proteome. Proteomics Clin Appl 4: 480-488.
43. Kubota H, (2002) Function and regulation of cytosolic molecular chaperone CCT. Vitam Horm 65: 313-331.
44. McCallum CD, Do H, Johnson AE, Frydman J, (2000) The interaction of the chaperonin tailless complex polypeptide 1 (TCP1) ring complex (TRiC) with ribosome-bound nascent chains examined using photo-cross-linking. J Cell Biol 149: 591-602.
45. Wang Q, Song C, Li CC, (2004) Molecular perspectives on p97-VCP: progress in understanding its structure and diverse biological functions. J Struct Biol 146: 44-57.
46. Mimnaugh EG, Xu W, Vos M, Yuan X, Neckers L, (2006) Endoplasmic reticulum vacuolization and valosin-containing protein relocalization result from simultaneous hsp90 inhibition by geldanamycin and proteasome inhibition by velcade. Mol Cancer Res 4: 667-681.
47. Chasis JA, Prenant M, Leung A, Mohandas N, (1989) Membrane assembly and remodeling during reticulocyte maturation. Blood 74: 1112-1120.
48. Liu J, Guo X, Mohandas N, Chasis JA, An X, (2010) Membrane remodeling during reticulocyte maturation. Blood 115: 2021-2027.
49. Ridley AJ, (2006) Rho GTPases and actin dynamics in membrane protrusions and vesicle trafficking. Trends Cell Biol 16: 522-529.
50. Hutagalung AH, Novick PJ, (2011) Role of Rab GTPases in membrane traffic and cell physiology. Physiol Rev 91: 119-149.
51. Frezza C, Zheng L, Folger O, Rajagopalan KN, MacKenzie ED, et al. (2011) Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase. Nature 477: 225-228.
52. van Kuilenburg AB, Zoetekouw L, Meijer J, Kuijpers TW, (2010) Identification of purine nucleoside phosphorylase deficiency in dried blood spots by a non-radiochemical assay using reversed-phase high-performance liquid chromatography. Nucleosides Nucleotides Nucleic Acids 29: 466-470.
53. Hallett RJ, Cronin SM, Morgan G, Duley JA, Fairbanks LD, et al. (1994) Normal uric acid concentrations in a purine nucleoside phosphorylase (PNP) deficient child presenting with severe chicken pox, possible immunodeficiency and developmental delay. Adv Exp Med Biol 370: 387-389.
54. Carpenter PA, Ziegler JB, Vowels MR, (1996) Late diagnosis and correction of purine nucleoside phosphorylase deficiency with allogeneic bone marrow transplantation. Bone Marrow Transplant 17: 121-124.
55. Notarangelo LD, (2009) Primary immunodeficiencies (PIDs) presenting with cytopenias. Hematology Am Soc Hematol Educ Program pp. 139-143.
56. Giblett ER, Ammann AJ, Wara DW, Sandman R, Diamond LK, (1975) Nucleoside-phosphorylase deficiency in a child with severely defective T-cell immunity and normal B-cell immunity. Lancet 1: 1010-1013.
57. Simmonds HA, Watson AR, Webster DR, Sahota A, Perrett D, (1982) GTP depletion and other erythrocyte abnormalities in inherited PNP deficiency. Biochem Pharmacol 31: 941-946.
58. Kanno H, Wei DC, Chan LC, Mizoguchi H, Ando M, et al. (1994) Hereditary hemolytic anemia caused by diverse point mutations of pyruvate kinase gene found in Japan and Hong Kong. Blood 84: 3505-3509.
59. Valentini G, Chiarelli LR, Fortin R, Dolzan M, Galizzi A, et al. (2002) Structure and function of human erythrocyte pyruvate kinase. Molecular basis of nonspherocytic hemolytic anemia. J Biol Chem 277: 23807-23814.
60. Zhu K ZJ, Lubman DM, Miller FR, Barder TJ, (2005) Protein pI shifts due to posttranslational modifications in the separation and characterization of proteins. Anal Chem 77: 2745-2755.
61. Beutler E, (1984) Red Cell Metabolism: A Manual of Biochemical Methods. New York, NY Grune & Stratton, Inc.
62. Carrell RW, Kay R, (1972) A simple method for the detection of unstable haemoglobins. Br J Haematol 23: 615-619.
63. Friedman DB, Hoving S, Westermeier R, (2009) Isoelectric focusing and two-dimensional gel electrophoresis. Methods Enzymol 463: 515-540.
64. Lee IN, Chen CH, Sheu JC, Lee HS, Huang GT, et al. (2005) Identification of human hepatocellular carcinoma-related biomarkers by two-dimensional difference gel electrophoresis and mass spectrometry. J Proteome Res 4: 2062-2069.
65. McDonald WH, Tabb DL, Sadygov RG, MacCoss MJ, Venable J, et al. (2004) MS1, MS2, and SQT-three unified, compact, and easily parsed file formats for the storage of shotgun proteomic spectra and identifications. Rapid Commun Mass Spectrom 18: 2162-2168.
66. Eng JK, McCormack AL, Yates JR Iii, (1994) An approach to correlate tandem mass spectral data of peptides with amino acid sequences in a protein database. Journal of the American Society for Mass Spectrometry 5: 976-989.
67. Dix MM, Simon GM, Cravatt BF, (2008) Global mapping of the topography and magnitude of proteolytic events in apoptosis. Cell 134: 679-691.
68. Yates JR, Cociorva D, Liao L, Zabrouskov V, (2006) Performance of a linear ion trap-Orbitrap hybrid for peptide analysis. Analytic Chemistry 78: 493-500.