Genetic characterization of an extended-spectrum AmpC cephalosporinase with hydrolysing activity against fourth-generation cephalosporins in a clinical isolate of Enterobacter aerogenes selected in vivo

Journal of Antimicrobial Chemotherapy

Volumn 67, Issue 1, 2012, Pages 64-68

  Rodríguez Martínez, Jose M ^a   Fernández Echauri, Pedro ^b   Fernández Cuenca, Felipe ^a,b   de Alba, Paula Diaz ^b   Briales, Alejandra ^a   Pascual, Alvaro ^a,b  

^a UNIVERSITY OF SEVILLE   (Spain)

^b HOSPITAL UNIVERSITARIO VIRGEN MACARENA   (Spain)

Author keywords

ESACs; Resistance; lactams

Indexed keywords

AMOXICILLIN; AZTREONAM; BETA LACTAMASE AMPC; CEFEPIME; CEFOTAXIME; CEFPIROME; CEFTAZIDIME; CEPHALOSPORIN DERIVATIVE; CEPHALOSPORINASE; CLOXACILLIN; EXTENDED SPECTRUM BETA LACTAMASE AMPC CEPHALOSPORINE; GLUTAMIC ACID; IMIPENEM; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; BACTERIAL DNA;

AMINO ACID SUBSTITUTION; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM ISOLATE; BROTH DILUTION; CONTROLLED STUDY; DRUG HYDROLYSIS; ENTEROBACTER AEROGENES; ENZYME ACTIVE SITE; ESCHERICHIA COLI; GENE SEQUENCE; IN VIVO STUDY; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN PURIFICATION; RECOMBINANT PLASMID; CHEMISTRY; DNA SEQUENCE; DRUG EFFECT; ENTEROBACTERIACEAE INFECTION; GENETIC SELECTION; GENETICS; HYDROLYSIS; ISOLATION AND PURIFICATION; METABOLISM; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; MOLECULAR GENETICS;

ANTI-BACTERIAL AGENTS; CEPHALOSPORINASE; CEPHALOSPORINS; DNA, BACTERIAL; ENTEROBACTER AEROGENES; ENTEROBACTERIACEAE INFECTIONS; HYDROLYSIS; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; SELECTION, GENETIC; SEQUENCE ANALYSIS, DNA;

EID: 84859199278     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkr423     Document Type: Article

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