CLL and deletion 13q14: Merely the miRs?

Blood

Volumn 119, Issue 13, 2012, Pages 2974-2975

  Mertens, Daniel ^a   Stilgenbauer, Stephan ^a  

^a UNIVERSITY OF ULM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MICRORNA;

ALLELE; CANCER CLASSIFICATION; CANCER PATIENT; CHROMOSOME ABERRATION; CHROMOSOME DELETION 13; CHROMOSOME DELETION 13Q14; CHRONIC LYMPHATIC LEUKEMIA; EPIGENETICS; GENE DELETION; GENE MUTATION; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC ASSOCIATION; HISTOPATHOLOGY; HUMAN; LYMPHOCYTOSIS; MONOCLONAL B CELL LYMPHOCYTOSIS; NONHODGKIN LYMPHOMA; NONHUMAN; NOTE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN PROCESSING; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TUMOR GROWTH; TUMOR LOCALIZATION; TUMOR SUPPRESSOR GENE;

EID: 84859172084     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-01-400747     Document Type: Note

References (11)

1. Lia M, Carette A, Tang H, et al. Functional dissection of the chromosome 13q14 tumor-suppressor locus using transgenic mouse lines. Blood. 2012;119(13):2981-2990.
2. Klein U, Lia M, Crespo M, et al. The DLEU2/ miR-15a/16-1 cluster controls B cell proliferation and its deletion leads to chronic lymphocytic leukemia. Cancer Cell. 2010;17(1):28-40.
3. Brown JR, Lawrence MS, Hanna M, et al. Novel germ-line genetic variants associated with familial chronic lymphocytic leukemia (CLL) [abstract]. ASH Annual Meeting Abstracts. 2011;118(21):465.
4. Calin GA, Ferracin M, Cimmino A, et al. A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia.N Engl J Med. 2005;353(17):1793-1801. (Pubitemid 41549891)
5. Allegra D, Mertens D. In-vivo quantification of primary microRNA processing by Drosha with a luciferase based system. Biochem Biophys Res Commun. 2011;406(4): 501-505.
6. Fulci V, Chiaretti S, Goldoni M, et al. Quantitative technologies establish a novel microRNA profile of chronic lymphocytic leukemia. Blood. 2007;109(11):4944-4951. (Pubitemid 46827793)
7. Ouillette P, Erba H, Kujawski L, Kaminski M, Shedden K, Malek SN. Integrated genomic profiling of chronic lymphocytic leukemia identifies subtypes of deletion 13q14. Cancer Res. 2008;68(4):1012-1021. (Pubitemid 351272218)
8. Fagerlund R, Kinnunen L, Kohler M, Julkunen I, Melen K. NF-{kappa}B is transported into the nucleus by importin {alpha}3 and importin {alpha}4. J Biol Chem. 2005;280(16):15942-15951. (Pubitemid 40616717)
9. Matsuda A, Suzuki Y, Honda G, et al. Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways. Oncogene. 2003;22(21):3307-3318. (Pubitemid 36712943)
10. Roccaro AM, Sacco A, Thompson B, et al. MicroRNAs 15a and 16 regulate tumor proliferation in multiple myeloma. Blood. 2009;113(26):6669-6680.
11. Palamarchuk A, Efanov A, Nazaryan N, et al. 13q14 deletions in CLL involve cooperating tumor suppressors. Blood. 2010;115(19):3916-3922.