FGFR3, PIK3CA and RAS mutations in benign lichenoid keratosis

British Journal of Dermatology

Volumn 166, Issue 4, 2012, Pages 784-788

  Groesser, L ^a   Herschberger, E ^a   Landthaler, M ^a   Hafner, C ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR RECEPTOR 3; PHOSPHATIDYLINOSITOL 3 KINASE; RAS PROTEIN;

ADULT; AGED; ARTICLE; BENIGN LICHENOID KERATOSIS; CONTROLLED STUDY; DNA ISOLATION; FEMALE; GENE MUTATION; GENETIC IDENTIFICATION; HUMAN; HUMAN TISSUE; KERATOSIS; LICHEN PLANUS; LICHENOID; LYMPHOCYTIC INFILTRATION; MAJOR CLINICAL STUDY; MALE; MICRODISSECTION; PATHOGENESIS; PRIORITY JOURNAL; WILD TYPE;

ADULT; AGED; AGED, 80 AND OVER; FEMALE; HUMANS; KERATOSIS; LICHEN PLANUS; LICHENOID ERUPTIONS; MALE; MIDDLE AGED; MUTATION; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS P21(RAS); RAS PROTEINS; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 3;

EID: 84859159497     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2011.10788.x     Document Type: Article

References (22)

1. Lumpkin LR, Helwig EB,. Solitary lichen planus. Arch Dermatol 1966; 93: 54-5.
2. Shapiro L, Ackerman AB,. Solitary lichen planus-like keratosis. Dermatologica 1966; 132: 386-92.
3. Morgan MB, Stevens GL, Switlyk S,. Benign lichenoid keratosis: a clinical and pathologic reappraisal of 1040 cases. Am J Dermatopathol 2005; 27: 387-92.
4. Prieto VG, Casal M, McNutt NS,. Immunohistochemistry detects differences between lichen planus-like keratosis, lichen planus, and lichenoid actinic keratosis. J Cutan Pathol 1993; 20: 143-7.
5. Jang KA, Kim SH, Choi JH, et al. Lichenoid keratosis: a clinicopathologic study of 17 patients. J Am Acad Dermatol 2000; 43: 511-16.
6. Mehregan AH,. Lentigo senilis and its evolutions. J Invest Dermatol 1975; 65: 429-33.
7. Berger TG, Graham JH, Goette DK,. Lichenoid benign keratosis. J Am Acad Dermatol 1984; 11: 635-8.
8. Zaballos P, Salsench E, Serrano P, et al. Studying regression of seborrheic keratosis in lichenoid keratosis with sequential dermoscopy imaging. Dermatology 2010; 220: 103-9.
9. Hafner C, Stoehr R, van Oers JM, et al. FGFR3 and PIK3CA mutations are involved in the molecular pathogenesis of solar lentigo. Br J Dermatol 2009; 160: 546-51.
10. Hafner C, Toll A, Fernandez-Casado A, et al. Multiple oncogenic mutations and clonal relationship in spatially distinct benign human epidermal tumors. Proc Natl Acad Sci USA 2010; 107: 20780-5.
11. Hafner C, van Oers JM, Vogt T, et al. Mosaicism of activating FGFR3 mutations in human skin causes epidermal nevi. J Clin Invest 2006; 116: 2201-7.
12. Hurst CD, Zuiverloon TC, Hafner C, et al. A SNaPshot assay for the rapid and simple detection of four common hotspot codon mutations in the PIK3CA gene. BMC Res Notes 2009; 2: 66.
13. Kompier LC, Lurkin I, van der Aa MN, et al. FGFR3, HRAS, KRAS, NRAS and PIK3CA mutations in bladder cancer and their potential as biomarkers for surveillance and therapy. PLoS One 2010; 5: e13821.
14. Bernard-Pierrot I, Brams A, Dunois-Larde C, et al. Oncogenic properties of the mutated forms of fibroblast growth factor receptor 3b. Carcinogenesis 2006; 27: 740-7.
15. Bonaventure J, Horne WC, Baron R,. The localization of FGFR3 mutations causing thanatophoric dysplasia type I differentially affects phosphorylation, processing and ubiquitylation of the receptor. FEBS J 2007; 274: 3078-93.
16. Ornitz DM, Marie PJ,. FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease. Genes Dev 2002; 16: 1446-65.
17. Gymnopoulos M, Elsliger MA, Vogt PK,. Rare cancer-specific mutations in PIK3CA show gain of function. Proc Natl Acad Sci USA 2007; 104: 5569-74.
18. Kalinsky K, Jacks LM, Heguy A, et al. PIK3CA mutation associates with improved outcome in breast cancer. Clin Cancer Res 2009; 15: 5049-59.
19. Zhao L, Vogt PK,. Hot-spot mutations in p110alpha of phosphatidylinositol 3-kinase (pI3K): differential interactions with the regulatory subunit p85 and with RAS. Cell Cycle 2010; 9: 596-600.
20. Goldenhersh MA, Barnhill RL, Rosenbaum HM, et al. Documented evolution of a solar lentigo into a solitary lichen planus-like keratosis. J Cutan Pathol 1986; 13: 308-11.
21. Prieto VG, Casal M, McNutt NS,. Lichen planus-like keratosis. A clinical and histological reexamination. Am J Surg Pathol 1993; 17: 259-63.
22. Goette DK,. Benign lichenoid keratosis. Arch Dermatol 1980; 116: 780-2.