Cardiovascular abnormalities in Down's syndrome: Spectrum, management and survival over 22 years

Archives of Disease in Childhood

Volumn 97, Issue 4, 2012, Pages 326-330

  Irving, Claire A ^a   Chaudhari, Milind P ^a  

^a FREEMAN HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CARDIOVASCULAR MALFORMATION; CONGESTIVE CARDIOMYOPATHY; DISEASE ASSOCIATION; DOWN SYNDROME; HEART ATRIUM SEPTUM DEFECT; HEART TRANSPLANTATION; HEART VENTRICLE SEPTUM DEFECT; HUMAN; INFANT; LIVE BIRTH; MAJOR CLINICAL STUDY; MORTALITY; PATENT DUCTUS ARTERIOSUS; PREVALENCE; PRIORITY JOURNAL; SURVIVAL TIME;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; DOWN SYNDROME; EISENMENGER COMPLEX; ENGLAND; HEART DEFECTS, CONGENITAL; HEART TRANSPLANTATION; HUMANS; INCIDENCE; INFANT; INFANT, NEWBORN; PROGNOSIS; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 84859157810     PISSN: 00039888     EISSN: 14682044     Source Type: Journal    
DOI: 10.1136/adc.2010.210534     Document Type: Article

References (20)

1. Tennant PW, Pearce MS, Bythell M, et al. 20-year survival of children born with congenital anomalies: a population-based study. Lancet 2010;375:649-56.
2. Freeman S B, Taft LF, Dooley KJ, et al. Population-based study of congenital heart defects in Down syndrome. Am J Med Genet 1998;80:213-17.
3. Wells G L, Barker SE, Finley SC, et al. C ongenital heart disease in infants with Down's syndrome. South Med J 1994;87:724-7.
4. Irving C, Basu A, Richmond S, et al. Twenty-year trends in prevalence and survival of Down syndrome. Eur J Hum Genet 2008;16:1336-40.
5. Bell R, Rankin J, Donaldson LJ. Down's syndrome: occurrence and outcome in the north of England, 1985-99. Paediatr Perinat Epidemiol 2003;17:33-9.
6. McElhinney D B, Wernovsky G. Outcomes of neonates with congenital heart disease. Curr Opin Pediatr 2001;13:104-10.
7. Dolk H. E UROCAT: 25 years of European surveillance of congenital anomalies. Arch Dis Child Fetal Neonatal Ed 2005;90:F355-8.
8. Jaiyesimi O, Baichoo V. Cardiovascular malformations in Omani Arab children with Down's syndrome. Cardiol Young 2007;17:166-71.
9. Vida V L, Barnoya J, Larrazabal LA, et al. Congenital cardiac disease in children with Down's syndrome in Guatemala. Cardiol Young 2005;15:286-90.
10. Lin AE, Basson CT, Goldmuntz E, et al. Adults with genetic syndromes and cardiovascular abnormalities: clinical history and management. Genet Med 2008;10:469-94.
11. McElhinney DB, Straka M, Goldmuntz E, et al. Correlation between abnormal cardiac physical examination and echocardiographic findings in neonates with Down syndrome. Am J Med Genet 2002;113:238-41.
12. Morris JK. The National Down Syndrome Cytogenetic Register 2007/2008 Annual Report. London: Barts and the London School of Medicine and Dentistry. Queen Mary University of London, 2009. http://www.wolfson.qmul. ac.uk/ndscr/
13. Shipp T D, Benacerraf B R. Second trimester ultrasound screening for chromosomal abnormalities. Prenat Diagn 2002;22:296-307.
14. Abu-Harb M, Wyllie J, Hey E, et al. Antenatal diagnosis of congenital heart disease and Down's syndrome: the potential effect on the practice of paediatric cardiology. Br Heart J 1995;74:192-8.
15. Gardiner H. Fetal echocardiography: 20 years of progress. Heart 2001; 86 (Suppl II):ii12-22.
16. Campbell RM, Adatia I, Gow RM, et al. Total cavopulmonary anastomosis (Fontan) in children with Down's syndrome. Ann Thorac Surg 1998;66:523-6.
17. Dadvand P, Rankin J, Shirley MD, et al. Descriptive epidemiology of congenital heart disease in Northern England. Paediatr Perinat Epidemiol 2009;23:58-65.
18. Frid C, Drott P, Lundell B, et al. Mortality in Down's syndrome in relation to congenital malformations. J Intellect Disabil Res 1999;43 (Pt 3):234-41.
19. Wren C, O'Sullivan JJ. Survival with congenital heart disease and need for follow up in adult life. Heart 2001;85:438-43.
20. Hayes C, Johnson Z, Thornton L, et al. Ten-year survival of Down syndrome births. Int J Epidemiol 1997;26:822-9.