Silencing of renal DnaseI in murine lupus nephritis imposes exposure of large chromatin fragments and activation of Toll like receptors and the Clec4e

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Thiyagarajan, Dhivya ^a   Fismen, Silje ^a   Seredkina, Natalya ^a   Jacobsen, Søren ^b   Elung Jensen, Thomas ^b   Kamper, Anne Lise ^b   Fenton, Christopher Graham ^a   Rekvig, Ole Petter ^a   Mortensen, Elin Synnøve ^a  

^a UNIVERSITY OF TROMSØ   (Norway)

^b Mental Health Center Glostrup   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CHROMATIN ANTIBODY; CLEC4E RECEPTOR; CYTOKINE; DEOXYRIBONUCLEASE I; GELATINASE A; GELATINASE B; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G ANTIBODY; IMMUNOSUPPRESSIVE AGENT; MATRIX METALLOPROTEINASE; MESSENGER RNA; RECEPTOR; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG; CLEC4D PROTEIN, HUMAN; CLECSF8 PROTEIN, MOUSE; IMMUNOGLOBULIN RECEPTOR; LECTIN; MEMBRANE PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHROMATIN; CONTROLLED STUDY; DISEASE COURSE; DOWN REGULATION; ENZYME INDUCTION; ENZYME REGULATION; GENE SILENCING; GLOMERULUS BASEMENT MEMBRANE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNE COMPLEX DEPOSITION; LUPUS ERYTHEMATOSUS NEPHRITIS; MOUSE; MOUSE STRAIN; NONHUMAN; PRINCIPAL COMPONENT ANALYSIS; PROTEIN EXPRESSION; ANIMAL; CELL CULTURE; CHEMISTRY; DISEASE MODEL; ENZYMOLOGY; FEMALE; GENETICS; INFLAMMATION; KIDNEY; METABOLISM; SIGNAL TRANSDUCTION;

MURINAE; MUS;

ANIMALS; CELLS, CULTURED; CHROMATIN; CYTOKINES; DEOXYRIBONUCLEASE I; DISEASE MODELS, ANIMAL; FEMALE; GENE SILENCING; HUMANS; INFLAMMATION; KIDNEY; LECTINS, C-TYPE; LUPUS NEPHRITIS; MEMBRANE PROTEINS; MICE; PRINCIPAL COMPONENT ANALYSIS; RECEPTORS, IMMUNOLOGIC; RNA, MESSENGER; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS;

EID: 84859118446     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0034080     Document Type: Article

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