Autologous stem cell therapy in the treatment of limb ischaemia induced chronic tissue ulcers of diabetic foot patients

International Journal of Clinical Practice

Volumn 66, Issue 4, 2012, Pages 384-393

  Kirana, S ^a   Stratmann, B ^a   Prante, C ^a   Prohaska, W ^a   Koerperich, H ^a   Lammers, D ^a   Gastens, M H ^a   Quast, T ^a   Negrean, M ^a   Stirban, O A ^a   Nandrean, S G ^a   Gotting C ^a   Minartz, P ^a   Kleesiek, K ^a   Tschoepe, Diethelm ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

THY 1 ANTIGEN;

ADULT; AGED; ANGIOGRAPHY; ANKLE BRACHIAL INDEX; ARTICLE; AUTOLOGOUS STEM CELL TRANSPLANTATION; CLINICAL ARTICLE; CONTROLLED STUDY; DIABETIC FOOT; ENRICHMENT CULTURE; FEMALE; FOLLOW UP; FOOT AMPUTATION; HUMAN; HYPEREMIA; LEG ISCHEMIA; LEG REVASCULARIZATION; MALE; MICROCIRCULATION; MONONUCLEAR CELL; MORTALITY; PATIENT SAFETY; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; TRANSCUTANEOUS OXYGEN MONITORING; TREATMENT OUTCOME; WOUND HEALING;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AMPUTATION; BONE MARROW TRANSPLANTATION; CHRONIC DISEASE; DIABETES MELLITUS, TYPE 1; DIABETES MELLITUS, TYPE 2; DIABETIC FOOT; FEASIBILITY STUDIES; HUMANS; ISCHEMIA; LEG; MIDDLE AGED; MONOCYTES; PROSPECTIVE STUDIES; STEM CELL TRANSPLANTATION; TRANSPLANTATION, AUTOLOGOUS; TREATMENT OUTCOME; WOUND HEALING; YOUNG ADULT;

EID: 84859109447     PISSN: 13685031     EISSN: 17421241     Source Type: Journal    
DOI: 10.1111/j.1742-1241.2011.02886.x     Document Type: Article

References (32)

1. Boulton AJ,. The pathogenesis of diabetic foot problems: an overview. Diabet Med 1996; 13 (Suppl 1): S12-6.
2. Consensus statement American Diabetes Association. Peripheral arterial disease in people with diabetes. Diabetes Care 2003; 26: 3333-41.
3. Prompers L, Huijberts M, Apelqvist J, et al., High prevalence of ischaemia, infection and serious comorbidity in patients with diabetic foot disease in Europe. Baseline results from the Eurodiale study. Diabetologia 2007; 50: 18-25. (Pubitemid 46035847)
4. Prompers L, Huijberts M, Apelqvist J, et al., Delivery of care to diabetic patients with foot ulcers in daily practice: results of the Eurodiale Study, a prospective cohort study. Diabet Med 2008; 25: 700-7. (Pubitemid 351782831)
5. Lawall H, Reike H,. Diabetic foot syndrome. Internist (Berl) 2009; 50: 936-44.
6. Norgren L, Hiatt WR, Dormandy JA, et al., Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II). J Vasc Surg 2007; 45 (Suppl S): S5-67. (Pubitemid 46151680)
7. Espinola-Klein C, Savvidis S,. Peripheral arterial disease: epidemiology, symptoms and diagnosis. Internist (Berl) 2009; 50: 919-26.
8. Tentolouris N, Al-Sabbagh S, Walker MG, Boulton AJ, Jude EB,. Mortality in diabetic and nondiabetic patients after amputations performed from 1990 to 1995: a 5-year follow-up study. Diabetes Care 2004; 27: 1598-604. (Pubitemid 38857432)
9. Collinson DJ, Donnelly R,. Therapeutic angiogenesis in peripheral arterial disease: can biotechnology produce an effective collateral circulation? Eur J Vasc Endovasc Surg 2004; 28: 9-23. (Pubitemid 38950133)
10. Siitonen OI, Niskanen LK, Laakso M, Siitonen JT, Pyorala K,. Lower-extremity amputations in diabetic and nondiabetic patients. A population-based study in eastern Finland. Diabetes Care 1993; 16: 16-20. (Pubitemid 23013819)
11. Chaturvedi N, Stevens LK, Fuller JH, Lee ET, Lu M,. Risk factors, ethnic differences and mortality associated with lower-extremity gangrene and amputation in diabetes. The WHO Multinational Study of Vascular Disease in Diabetes. Diabetologia 2001; 44 (Suppl 2): S65-71. (Pubitemid 32844114)
12. Iversen MM, Tell GS, Riise T, et al., Mortality among persons with diabetes. 10-year follow-up of the Nord-Trondelag Health Study, Norway. Diabetes Care 2009; 32: 2193-99.
13. Heller G, Gunster C, Swart E,. The frequency of lower limb amputations in Germany. Dtsch Med Wochenschr 2005; 130: 1689-90. (Pubitemid 41150996)
14. Minar E,. Critical limb ischaemia. Hamostaseologie 2009; 29: 102-9.
15. Velazquez O,. Angiogenesis and vasculogenesis: inducing the growth of new blood vessels and wound healing by stimulation of bone marrow-derived progenitor cell mobilization and homing. J Vasc Surg 2007; 45 (Suppl A): A39-47.
16. Bauer SM, Bauer RJ, Velazquez OC,. Angiogenesis, vasculogenesis and induction of healing in chronic wounds. Vasc Endovascular Surg 2005; 39: 293-306. (Pubitemid 41061696)
17. Kim DI, Kim MJ, Joh JH, et al., Angiogenesis facilitated by autologous whole bone marrow stem cell transplantation for Buerger's disease. Stem Cells 2006; 24: 1194-200.
18. Tateishi-Yuyama E, Matsubara H, Murohara T, et al., Therapeutic Angiogenesis using Cell Transplantation (TACT) Study Investigators. Therapeutic angiogenesis for patients with limb ischaemia by autologous transplantation of bone-marrow cells: a pilot study and a randomised controlled trial. Lancet 2002; 360: 427-35.
19. Nikol S,. Therapeutic angiogenesis for peripheral artery disease: gene therapy. Vasa 2007; 36: 165-73. (Pubitemid 47327004)
20. Esato K, Hamano K, Li TS, et al., Neovascularisation induced by autologous bone marrow cell implantation in peripheral arterial disease. Cell Transplant 2002; 11: 747-52. (Pubitemid 36176786)
21. Bartsch T, Brehm M, Zeus T, et al., Transplantation of autologous mononuclear bone marrow stem cells in patients with peripheral arterial disease (the TAM-PAD study). Clin Res Cardiol 2007; 96: 891-9. (Pubitemid 350164931)
22. Amann B, Luedemann C, Ratei R, Schmidt-Lucke JA,. Autologous bone marrow cell transplantation increases leg perfusion and reduces amputations in patients with advanced critical limb ischaemia due to peripheral artery disease. Cell Transplant 2009; 18: 371-80.
23. Nakanishi C, Yamagishi M, Yamahara K, et al., Activation of cardiac progenitor cells through paracrine effects of mesenchymal stem cells. Biochem Biophys Res Commun 2008; 374: 11-6.
24. Li Z, Guo J, Chang Q, Zhang A,. Paracrine role for mesenchymal stem cells in acute myocardial infarction. Biol Pharm Bull 2009; 32: 1343-6.
25. Burt RK, Loh Y, Pearce W, et al., Clinical applications of blood-derived and marrow-derived stem cells for nonmalignant diseases. JAMA 2008; 299: 925-36. (Pubitemid 351397068)
26. Gastens MH, Goltry K, Prohaska W, et al., Good manufacturing practice-compliant expansion of marrow-derived stem and progenitor cells for cell therapy. Cell Transplant 2007; 16: 685-96. (Pubitemid 351448264)
27. Rodriguez L, Azqueta C, Azzalin S, Garcia J, Querol S,. Washing of cord blood grafts after thawing: high cell recovery using an automated and closed system. Vox Sang 2004; 87: 165-72. (Pubitemid 39469774)
28. Oswald J, Boxberger S, Jorgensen B, et al., Mesenchymal stem cells can be differentiated into endothelial cells in vitro. Stem Cells 2004; 22: 377-84. (Pubitemid 38736621)
29. Lemarie C, Calmels B, Malenfant C, et al., Clinical experience with the delivery of thawed and washed autologous blood cells, with an automated closed fluid management device: cytomate. Transfusion 2005; 45: 737-42. (Pubitemid 40656387)
30. Kirana S, Stratmann B, Lammers D, et al., Wound therapy with autologous bone marrow stem cells in diabetic patients with ischaemia-induced tissue ulcers affecting the lower limbs. Int J Clin Pract 2007; 61: 690-2. (Pubitemid 46449824)
31. Wyss CR, Robertson C, Love SJ, Harrington RM, Matsen FA 3rd,. Relationship between transcutaneous oxygen tension, ankle blood pressure, and clinical outcome of vascular surgery in diabetic and nondiabetic patients. Surgery 1987; 101: 56-62. (Pubitemid 17218379)
32. Faglia E, Clerici G, Caminiti M, et al., Predictive values of transcutaneous oxygen tension for above-the-ankle amputation in diabetic patients with critical limb ischaemia. Eur J Vasc Endovasc Surg 2007; 33: 731-6. (Pubitemid 46672819)