Modeling dispersion of dry powders for inhalation. the concepts of total fines, cohesive energy and interaction parameters

International Journal of Pharmaceutics

Volumn 427, Issue 2, 2012, Pages 224-233

  Thalberg, Kyrre ^a   Berg, Elna ^a   Fransson, Magnus ^a  

^a ASTRAZENECA R AND D   (Sweden)

Author keywords

Cohesive energy; Dispersion; Dry powder formulation; Fine particle fraction; Modeling; Total fines

Indexed keywords

BECLOMETASONE DIPROPIONATE; BUDESONIDE; LACTOSE;

ARTICLE; CHEMICAL COMPOSITION; CHEMICAL INTERACTION; CHEMICAL PARAMETERS; DISPERSION; DRUG FORMULATION; DRY POWDER; ENERGY; INHALATION; MODEL; PARTICLE SIZE; PARTICULATE MATTER; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY;

ADMINISTRATION, INHALATION; ALGORITHMS; ANTI-ASTHMATIC AGENTS; BECLOMETHASONE; BRONCHODILATOR AGENTS; BUDESONIDE; CHEMISTRY, PHARMACEUTICAL; DRUG CARRIERS; DRUG COMPOUNDING; DRY POWDER INHALERS; LACTOSE; MICROSCOPY, ELECTRON, SCANNING; MODELS, STATISTICAL; PARTICLE SIZE; POWDERS; REPRODUCIBILITY OF RESULTS; SOFTWARE;

EID: 84859107135     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2012.02.009     Document Type: Article

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