Quercetin is more effective than cromolyn in blocking human mast cell cytokine release and inhibits contact dermatitis and photosensitivity in humans

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Weng, Zuyi ^a,b   Zhang, Bodi ^a,b   Asadi, Shahrzad ^a,c   Sismanopoulos, Nikolaos ^a   Butcher, Alan ^d   Fu, Xueyan ^e   Katsarou Katsari, Alexandra ^f   Antoniou, Christina ^f   Theoharides, Theoharis C ^a,b  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TUFTS UNIVERSITY   (United States)

^c TUFTS MEDICAL CENTER   (United States)

^d Thorne Research Incorporated   (United States)

^e TUFTS UNIVERSITY   (United States)

^f UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CROMOGLYCATE DISODIUM; HISTAMINE; IMMUNOGLOBULIN E; IMMUNOGLOBULIN E ANTIBODY; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; INTERLEUKIN 8; LEUKOTRIENE; PROSTAGLANDIN D2; QUERCETIN; SUBSTANCE P; TUMOR NECROSIS FACTOR ALPHA; ANTI-IGE; ANTIALLERGIC AGENT; ANTIIDIOTYPIC ANTIBODY;

ADULT; ARTICLE; CELL STIMULATION; CLINICAL ARTICLE; CONTACT DERMATITIS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG EFFICACY; FEMALE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; IN VIVO STUDY; MAST CELL; MAST CELL DEGRANULATION; PHARMACOLOGICAL BLOCKING; PHOTOSENSITIVITY; PILOT STUDY; ANTIGEN ANTIBODY COMPLEX; CELL CULTURE; DRUG EFFECT; HYPERSENSITIVITY; IMMUNOLOGY; METABOLISM;

ANTI-ALLERGIC AGENTS; ANTIBODIES, ANTI-IDIOTYPIC; ANTIGEN-ANTIBODY COMPLEX; CALCIUM; CELLS, CULTURED; CROMOLYN SODIUM; DERMATITIS, CONTACT; HISTAMINE; HUMANS; HYPERSENSITIVITY; IMMUNOGLOBULIN E; INTERLEUKIN-6; INTERLEUKIN-8; LEUKOTRIENES; MAST CELLS; NF-KAPPA B; PROSTAGLANDIN D2; QUERCETIN;

EID: 84859093120     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0033805     Document Type: Article

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