A multicenter, randomized controlled trial of immediate total-body CT scanning in trauma patients (REACT-2)

BMC Emergency Medicine

Volumn 12, Issue , 2012, Pages

  Sierink, Joanne C ^a   Saltzherr, Teun P ^a   Beenen, Ludo F M ^a   Luitse, Jan S K ^a   Hollmann, Markus W ^a   Reitsma, Johannes B ^a   Edwards, Michael J R ^b   Hohmann, Joachim ^c   Beuker, Benn J A ^d   Patka, Peter ^e   Suliburk, James W ^f   W Dijkgraaf, Marcel G ^a   Goslings, J Carel ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c UNIVERSITY HOSPITAL BASEL   (Switzerland)

^d UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^e ERASMUS MEDICAL CENTER   (Netherlands)

^f BEN TAUB GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONTRAST ENHANCEMENT; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; EMERGENCY WARD; HEALTH STATUS; HUMAN; IMAGE ANALYSIS; INJURY; INJURY SEVERITY; MORBIDITY; MORTALITY; MULTICENTER STUDY; QUALITY OF LIFE; RADIATION EXPOSURE; RANDOMIZED CONTROLLED TRIAL; RESUSCITATION; TOTAL BODY COMPUTED ASSISTED TOMOGRAPHY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; COST BENEFIT ANALYSIS; EMERGENCY HEALTH SERVICE; FEMALE; GLASGOW COMA SCALE; INJURY SCALE; MALE; METHODOLOGY; ORGANIZATION AND MANAGEMENT; PROSPECTIVE STUDY; RADIOGRAPHY; WHOLE BODY IMAGING;

ADULT; COST-BENEFIT ANALYSIS; FEMALE; GLASGOW COMA SCALE; HOSPITAL MORTALITY; HUMANS; INJURY SEVERITY SCORE; MALE; PROSPECTIVE STUDIES; QUALITY OF LIFE; RESEARCH DESIGN; TOMOGRAPHY, X-RAY COMPUTED; TRAUMA CENTERS; WHOLE BODY IMAGING; WOUNDS AND INJURIES; YOUNG ADULT;

EID: 84859069679     PISSN: None     EISSN: 1471227X     Source Type: Journal    
DOI: 10.1186/1471-227X-12-4     Document Type: Article

References (33)

1. World Health Organization The global burden of disease: 2004 update. 2008, 6-12-2010, World Health Organization., http://www.who.int/healthinfo/global_burden_disease/2004_report_update/en/index.html
2. Sethi D, Racioppi F, Baumgarten I, Bertollini R. Reducing inequalities from injuries in Europe. Lancet 2006, 368:2243-2250. 10.1016/S0140-6736(06)68895-8, 17189036.
3. American College of Surgeons Committee on Trauma ATLS advanced trauma life support program for doctors. Student Course Manual 2008, Chigago, IL, 8, American College of Surgeons Committee on Trauma.
4. Leidner B, Beckman MO. Standardized whole-body computed tomography as a screening tool in blunt multitrauma patients. Emerg Radiol 2001, 8:20-28.
5. Sampson MA, Colquhoun KB, Hennessy NL. Computed tomography whole body imaging in multi-trauma: 7years experience. Clin Radiol 2006, 61:365-369. 10.1016/j.crad.2005.12.009, 16546467.
6. Linsenmaier U, Krotz M, Hauser H, Rock C, Rieger J, Bohndorf K, et al. Whole-body computed tomography in polytrauma: techniques and management. Eur Radiol 2002, 12:1728-1740. 10.1007/s00330-001-1225-x, 12111064.
7. Smith CM, Woolrich-Burt L, Wellings R, Costa ML. Major trauma CT scanning: the experience of a regional trauma centre in the UK. Emerg Med J 2011, 28:378-382. 10.1136/emj.2009.076414, 20515906.
8. Rieger M, Czermak B, El AR, Sumann G, Jaschke W, Freund M. Initial clinical experience with a 64-MDCT whole-body scanner in an emergency department: better time management and diagnostic quality?. J Trauma 2009, 66:648-657. 10.1097/TA.0b013e31816275f3, 19276733.
9. Salim A, Sangthong B, Martin M, Brown C, Plurad D, Demetriades D. Whole body imaging in blunt multisystem trauma patients without obvious signs of injury: results of a prospective study. Arch Surg 2006, 141:468-473. 10.1001/archsurg.141.5.468, 16702518.
10. Albrecht T, Von SJ, Stahel PF, Ertel W, Wolf KJ. [The role of whole body spiral CT in the primary work-up of polytrauma patients--comparison with conventional radiography and abdominal sonography]. Rofo 2004, 176:1142-1150. 10.1055/s-2004-813259, 15346611.
11. Saltzherr TP, Bakker FC, Beenen LFM, Dijkgraaf MGW, Reitsma JB, Goslings JC, et al. Randomized clinical trial comparing the effect of computed tomography in the trauma room versus the radiology department on injury outcomes. Br J Surg 2012, 99:105-113.
12. Fung Kon Jin PH, Goslings JC, Ponsen KJ, van KC, Hoogerwerf N, Luitse JS. Assessment of a new trauma workflow concept implementing a sliding CT scanner in the trauma room: the effect on workup times. J Trauma 2008, 64:1320-1326. 10.1097/TA.0b013e318059b9ae, 18469657.
13. Ptak T, Rhea JT, Novelline RA. Experience with a continuous, single-pass whole-body multidetector CT protocol for trauma: The three-minute multiple trauma CT scan. Emerg Radiol 2001, 8:250-256.
14. Philipp MO, Kubin K, Hormann M, Metz VM. Radiological emergency room management with emphasis on multidetector-row CT. Eur J Radiol 2003, 48:2-4. 10.1016/S0720-048X(03)00206-7, 14511855.
15. Kanz KG, Korner M, Linsenmaier U, Kay MV, Huber-Wagner SM, Kreimeier U, et al. Priority-oriented shock trauma room management with the integration of multiple-view spiral computed tomography. Unfallchirurg 2004, 107:937-944. 10.1007/s00113-004-0845-4, 15452654.
16. Prokop A, Hotte H, Kruger K, Rehm KE, Isenberg J, Schiffer G. Multislice CT in diagnostic work-up of polytrauma. Unfallchirurg 2006, 109:545-550. 10.1007/s00113-006-1086-5, 16636783.
17. Gralla J, Spycher F, Pignolet C, Ozdoba C, Vock P, Hoppe H. Evaluation of a 16-MDCT scanner in an emergency department: initial clinical experience and workflow analysis. AJR Am J Roentgenol 2005, 185:232-238.
18. Fung Kon Jin PH, van Geene AR, Linnau KF, Jurkovich GJ, Ponsen KJ, Goslings JC. Time factors associated with CT scan usage in trauma patients. Eur J Radiology 2009, 72(1):134-138.
19. Leidner B, Adiels M, Aspelin P, Gullstrand P, Wallen S. Standardized CT examination of the multitraumatized patient. Eur Radiol 1998, 8:1630-1638. 10.1007/s003300050601, 9866776.
20. Fanucci E, Fiaschetti V, Rotili A, Floris R, Simonetti G. Whole body 16-row multislice CT in emergency room: effects of different protocols on scanning time, image quality and radiation exposure. Emerg Radiol 2007, 13:251-257. 10.1007/s10140-006-0554-0, 17180674.
21. Nguyen D, Platon A, Shanmuganathan K, Mirvis SE, Becker CD, Poletti PA. Evaluation of a single-pass continuous whole-body 16-MDCT protocol for patients with polytrauma. AJR Am J Roentgenol 2009, 192:3-10. 10.2214/AJR.07.3702, 19098172.
22. Weninger P, Mauritz W, Fridrich P, Spitaler R, Figl M, Kern B, et al. Emergency room management of patients with blunt major trauma: evaluation of the multislice computed tomography protocol exemplified by an urban trauma center. J Trauma 2007, 62:584-591. 10.1097/01.ta.0000221797.46249.ee, 17414332.
23. Wurmb T, Balling H, Fruhwald P, Keil T, Kredel M, Meffert R, et al. Polytrauma management in a period of change. Unfallchirurg 2009, 112:390-399. 10.1007/s00113-008-1528-3, 19159120.
24. Wurmb TE, Quaisser C, Balling H, Kredel M, Muellenbach R, Kenn W, et al. Whole-body multislice computed tomography (MSCT) improves trauma care in patients requiring surgery after multiple trauma. Emerg Med J 2011, 28:300-304. 10.1136/emj.2009.082164, 20659885.
25. Huber-Wagner S, Lefering R, Qvick LM, Korner M, Kay MV, Pfeifer KJ, et al. Effect of whole-body CT during trauma resuscitation on survival: a retrospective, multicentre study. Lancet 2009, 373:1455-1461. 10.1016/S0140-6736(09)60232-4, 19321199.
26. Sierink JC, Saltzherr TP, Reitsma JB, Van Delden OM, Luitse JSK, Goslings JC. Systematic review and meta-analysis of immediate total-body computed tomography compared with selective radiological imaging of injured patients. Br J Surg 2012, 99:52-58. 10.1002/bjs.7760, 22441856.
27. Ptak T, Rhea JT, Novelline RA. Radiation dose is reduced with a single-pass whole-body multi-detector row CT trauma protocol compared with a conventional segmented method: initial experience. Radiology 2003, 229:902-905. 10.1148/radiol.2293021651, 14657320.
28. Ruchholtz S, Waydhas C, Schroeder T, Piepenbrink K, Kuhl H, Nast-Kolb D. The value of computed tomography in the early treatment of seriously injured patients. Chirurg 2002, 73:1005-1012. 10.1007/s00104-002-0429-1, 12395159.
29. Hilbert P, Zur NK, Hofmann GO, Hoeller I, Koch R, Stuttmann R. New aspects in the emergency room management of critically injured patients: a multi-slice CT-oriented care algorithm. Injury 2007, 38:552-558. 10.1016/j.injury.2006.12.023, 17472791.
30. WMA Declaration of Helsinki - Ethical Principles for Medical Research Involving Human Subjects. 2011, , http://www.wma.net/en/30publications/10policies/b3/
31. Brenner DJ, Elliston CD. Estimated radiation risks potentially associated with full-body CT screening. Radiology 2004, 232:735-738. 10.1148/radiol.2323031095, 15273333.
32. Tien HC, Tremblay LN, Rizoli SB, Gelberg J, Spencer F, Caldwell C, et al. Radiation exposure from diagnostic imaging in severely injured trauma patients. J Trauma 2007, 62:151-156. 10.1097/TA.0b013e31802d9700, 17215747.
33. Kim PK, Gracias VH, Maidment AD, O'Shea M, Reilly PM, Schwab CW. Cumulative radiation dose caused by radiologic studies in critically ill trauma patients. J Trauma 2004, 57:510-514. 10.1097/01.TA.0000141028.97753.67, 15454795.