메뉴 건너뛰기




Volumn 7, Issue 3, 2012, Pages

Highly parallel translation of dna sequences into small molecules

Author keywords

[No Author keywords available]

Indexed keywords

ACCURACY; ARTICLE; COMBINATORIAL CHEMISTRY; CONJUGATION; DEVICES; DNA SEQUENCE; EVOLUTION; GENETIC CODE; IN VITRO STUDY; MESOFLUIDIC DEVICE; GENE LIBRARY; GENETICS; INSTRUMENTATION; METHODOLOGY; MICROFLUIDIC ANALYSIS; MOLECULAR LIBRARY; PROTEIN SYNTHESIS; REPRODUCIBILITY;

EID: 84859048365     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0028056     Document Type: Article
Times cited : (25)

References (24)
  • 1
    • 9344223986 scopus 로고    scopus 로고
    • Human antibodies with sub-nanomolar affinities isolated from a large non-immunized phage display library
    • Vaughan TJ, Williams AJ, Pritchard K, Osbourn JK, Pope AR, et al. (1996) Human antibodies with sub-nanomolar affinities isolated from a large non-immunized phage display library. Nature biotechnology 14: 309-314.
    • (1996) Nature Biotechnology , vol.14 , pp. 309-314
    • Vaughan, T.J.1    Williams, A.J.2    Pritchard, K.3    Osbourn, J.K.4    Pope, A.R.5
  • 3
    • 0026575221 scopus 로고
    • Selection of single-stranded DNA molecules that bind and inhibit human thrombin
    • Bock LC, Griffin LC, Latham JA, Vermaas EH, Toole JJ, (1992) Selection of single-stranded DNA molecules that bind and inhibit human thrombin. Nature 355: 564-566.
    • (1992) Nature , vol.355 , pp. 564-566
    • Bock, L.C.1    Griffin, L.C.2    Latham, J.A.3    Vermaas, E.H.4    Toole, J.J.5
  • 5
    • 0029295966 scopus 로고
    • Dissecting protein:protein interactions between transcription factors with an RNA aptamer
    • Tian Y, Adya N, Wagner S, Giam CZ, Green MR, et al. (1995) Dissecting protein:protein interactions between transcription factors with an RNA aptamer. RNA 1: 317-326.
    • (1995) RNA , vol.1 , pp. 317-326
    • Tian, Y.1    Adya, N.2    Wagner, S.3    Giam, C.Z.4    Green, M.R.5
  • 6
    • 34548603604 scopus 로고    scopus 로고
    • Chemical evolution as a tool for molecular discovery
    • Wrenn SJ, Harbury PB, (2007) Chemical evolution as a tool for molecular discovery. Annual review of biochemistry 76: 331-349.
    • (2007) Annual Review of Biochemistry , vol.76 , pp. 331-349
    • Wrenn, S.J.1    Harbury, P.B.2
  • 7
    • 77952543008 scopus 로고    scopus 로고
    • Selecting chemicals: the emerging utility of DNA-encoded libraries
    • Clark MA, (2010) Selecting chemicals: the emerging utility of DNA-encoded libraries. Current opinion in chemical biology 14: 396-403.
    • (2010) Current Opinion in Chemical Biology , vol.14 , pp. 396-403
    • Clark, M.A.1
  • 8
    • 0035289779 scopus 로고    scopus 로고
    • Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings
    • Lipinski CA, Lombardo F, Dominy BW, Feeney PJ, (2001) Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings. Advanced drug delivery reviews 46: 3-26.
    • (2001) Advanced Drug Delivery Reviews , vol.46 , pp. 3-26
    • Lipinski, C.A.1    Lombardo, F.2    Dominy, B.W.3    Feeney, P.J.4
  • 11
    • 77955792293 scopus 로고    scopus 로고
    • In vitro selection of a DNA-templated small-molecule library reveals a class of macrocyclic kinase inhibitors
    • Kleiner RE, Dumelin CE, Tiu GC, Sakurai K, Liu DR, (2010) In vitro selection of a DNA-templated small-molecule library reveals a class of macrocyclic kinase inhibitors. Journal of the American Chemical Society 132: 11779-11791.
    • (2010) Journal of the American Chemical Society , vol.132 , pp. 11779-11791
    • Kleiner, R.E.1    Dumelin, C.E.2    Tiu, G.C.3    Sakurai, K.4    Liu, D.R.5
  • 12
    • 77958173306 scopus 로고    scopus 로고
    • Isolation of potent and specific trypsin inhibitors from a DNA-encoded chemical library
    • Mannocci L, Melkko S, Buller F, Molnar I, Bianke JP, et al. (2010) Isolation of potent and specific trypsin inhibitors from a DNA-encoded chemical library. Bioconjugate chemistry 21: 1836-1841.
    • (2010) Bioconjugate Chemistry , vol.21 , pp. 1836-1841
    • Mannocci, L.1    Melkko, S.2    Buller, F.3    Molnar, I.4    Bianke, J.P.5
  • 14
    • 0025194307 scopus 로고
    • Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase
    • Tuerk C, Gold L, (1990) Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science 249: 505-510.
    • (1990) Science , vol.249 , pp. 505-510
    • Tuerk, C.1    Gold, L.2
  • 15
    • 0025074907 scopus 로고
    • In vitro selection of RNA molecules that bind specific ligands
    • Ellington AD, Szostak JW, (1990) In vitro selection of RNA molecules that bind specific ligands. Nature 346: 818-822.
    • (1990) Nature , vol.346 , pp. 818-822
    • Ellington, A.D.1    Szostak, J.W.2
  • 16
    • 0024443885 scopus 로고
    • Amplification, mutation and selection of catalytic RNA
    • Joyce GF, (1989) Amplification, mutation and selection of catalytic RNA. Gene 82: 83-87.
    • (1989) Gene , vol.82 , pp. 83-87
    • Joyce, G.F.1
  • 17
    • 0025112794 scopus 로고
    • Searching for peptide ligands with an epitope library
    • Scott JK, Smith GP, (1990) Searching for peptide ligands with an epitope library. Science 249: 386-390.
    • (1990) Science , vol.249 , pp. 386-390
    • Scott, J.K.1    Smith, G.P.2
  • 20
    • 0034237264 scopus 로고    scopus 로고
    • Diversity screening versus focussed screening in drug discovery
    • Valler MJ, Green D, (2000) Diversity screening versus focussed screening in drug discovery. Drug discovery today 5: 286-293.
    • (2000) Drug Discovery Today , vol.5 , pp. 286-293
    • Valler, M.J.1    Green, D.2
  • 21
    • 11144320699 scopus 로고    scopus 로고
    • Navigating chemical space for biology and medicine
    • Lipinski C, Hopkins A, (2004) Navigating chemical space for biology and medicine. Nature 432: 855-861.
    • (2004) Nature , vol.432 , pp. 855-861
    • Lipinski, C.1    Hopkins, A.2
  • 24
    • 19344364293 scopus 로고    scopus 로고
    • DNA display I. Sequence-encoded routing of DNA populations
    • Halpin DR, Harbury PB, (2004) DNA display I. Sequence-encoded routing of DNA populations. PLoS biology 2: E173.
    • (2004) PLoS Biology , vol.2
    • Halpin, D.R.1    Harbury, P.B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.