Efficacy of buffered hypertonic saline nasal irrigation in children with symptomatic allergic rhinitis: A randomized double-blind study

International Journal of Pediatric Otorhinolaryngology

Volumn 76, Issue 4, 2012, Pages 583-588

  Satdhabudha, A ^a   Poachanukoon, O ^a,b  

^a THAMMASAT UNIVERSITY   (Thailand)

^b THAMMASAT UNIVERSITY   (Thailand)

Author keywords

Allergic rhinitis; Buffered hypertonic saline nasal irrigation; Normal isotonic saline nasal irrigation; Saccharine clearance time

Indexed keywords

ANTIHISTAMINIC AGENT; BUFFER NORMAL SALINE; BUFFERED HYPERTONIC SALINE; CORTICOSTEROID; PLACEBO; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ADOLESCENT; ALLERGIC RHINITIS; ARTICLE; CHILD; CLINICAL ASSESSMENT; CLINICAL EFFECTIVENESS; COMPARATIVE STUDY; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; NASAL LAVAGE; NOSE CONGESTION; PATIENT SATISFACTION; PRESCHOOL CHILD; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUALITY OF LIFE; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; SAFETY; SCORING SYSTEM; TREATMENT DURATION; TREATMENT RESPONSE;

ADOLESCENT; BUFFERS; CHILD; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; MUCOCILIARY CLEARANCE; NASAL LAVAGE; PATIENT SATISFACTION; PROSPECTIVE STUDIES; QUALITY OF LIFE; RHINITIS, ALLERGIC, SEASONAL; SALINE SOLUTION, HYPERTONIC; TREATMENT OUTCOME;

EID: 84859003879     PISSN: 01655876     EISSN: 18728464     Source Type: Journal    
DOI: 10.1016/j.ijporl.2012.01.022     Document Type: Article

References (28)

1. Bunnag C., Jareoncharsri P., Tantilipidorn P., Vichyanond P., Pawankar R. Epidemiology and current status of allergic rhinitis and asthma in Thailand. Asian Pac. J. Allergy Immunol. 2009, 27(1):79-86.
2. The international study of asthmal and allergies in childhood (ISSAC) steering committee. Lancet 1998, 1225-1232.
3. Wright A.L., Holberg C.J., Halonen M., Martinez F.D., Morgan W., Taussig L.M. Epidemiology of physician-diagnosed allergic rhinitis in childhood. Pediatrics 1994, 94:895-901.
4. Uthaisangsook S. Prevalence of asthma, rhinitis, and eczema in the university population of Phitsanulok, Thailand. Asian Pac. J. Allergy Immunol. 2007, 25(2-3):127-132.
5. Teeratakulpisarn J., Wiangnon S., Kosalaraksa P., Heng S. Surveying the prevalence of asthma, allergic rhinitis and eczema in school-children in Khon Kaen, Northeastern Thailand using the ISAAC questionnaire: phase 3. Asian Pac. J. Allergy Immunol. 2004, 22(4):175-181.
6. Trakultivakorn M., Sangsupawanich P., Vichyanond P. Time trends of the prevalence of asthma, rhinitis and eczema in Thai children-ISAAC (International Study of Asthma and Allergies in Childhood) Phase Three. J. Asthma 2007, 44(8):609-611.
7. Juniper E., Guyalt G., Dolovich J. Clinical aspects of allergic desease. Assessment of quality of life in adolescents with allergic rhinoconjunctivitis: development and testing of a questionnaire for clinical trial. Allergy Clin. Immunol. 1994, 93:413-423.
8. Rabago D., Zgierska A. Saline nasal irrigation for upper respiratory conditions. Am. Fam. Physician 2009, 1117-1119.
9. Rabago D., Guerard E., Bukstein D. Nasal irrigation for chronic sinus symptoms in patients with allergic rhinitis, asthma and nasal polyposis: a hypothesis generating study. WMJ 2008, 107(2):69-75.
10. Brown C., Graham S. Nasal irrigations: good or bad?. Curr. Opin. Otolaryngol. Head Neck Surg. 2004, 12:9-13.
11. Hauptman G., Ryan M. The effect of saline solutions on nasal patency and mucociliary clearance in rhinosinusitis patients. Otolaryngol. Head Neck Surg. 2007, 135(5):815-821.
12. Keojampa B., Nguyen M., Ryan M. Effects of buffered saline solution on nasal mucociliary clearance and nasal airway patency. Otolaryngol. Head Neck Surg. 2004, 131(5):679-682.
13. Talbot A.R., Herr T., Parsons D. Mucociliary clearance and buffered hypertonic saline. Laryngoscope 1997, 107:500-503.
14. Shoseyov D., Bibi H., Shai P., Shoseyov N., Shazberg G., Hurvitz H. Treatment with hypertonic saline versus normal saline nasal wash of pediatric chronic sinusitis. J. Allergy Clin. Immunol. 1998, 101:602-605.
15. Suslu N., Bajin M., Suslu A. Effects of buffered 2.3%, buffered 0.9%, and non-buffered 0.9% irrigation solutions on nasal mucosa after septoplasty. Eur. Arch. Otorhinolaryngol. 2009, 226:685-689.
16. Luk C., Dulfano M. Effect of pH, viscosity and ionic-strength changes on ciliary beating frequency of human bronchial explants. Clin. Sci. (Lond.) 1983, 64(4):449-451.
17. Baraniuk J.N., Ali M., Yuta A. Hypersaline nasal provocation stimulates nociceptive nerves, substance P. release, and glandular mucous exocytosis in normal humans. Am. J. Respir. Crit. Care Med. 1999, 160:655-662.
18. Krayenbuhl M., Hudspith B., Brostoff J., Scadding G., Guesdon J., Latchman Y. Nasal histamine release following hyperosmolar and allergen challenge. Allergy 1989, 44:25-29.
19. Garavello W., Romagnoli M., Sordo L., Gaini R., Di Berardino C., Angrisano A. Hypersaline nasal irrigation in children with symptomatic seasonal allergic rhinitis: a randomized study. Pediatr. Allergy Immunol. 2003, 14:140-143.
20. Harvey R., Hannan S., Badia L., Scadding G. Nasal saline irrigations for the symptoms of chronic rhinosinusitis. Otolaryngol. Head Neck Surg. 2007, 137(4):532-534.
21. Ural A., Oktemer T.K., Kizil Y., Ileri F., Uslu S. Impact of isotonic and hypertonic saline solutions on mucociliary activity in various nasal pathologies: clinical study. J. Laryngol. Otol. 2009, 123(5):517-521.
22. Rabago D., Pasic T., Zgierska A., Barrett B., Mundt M., Maberry R. The efficacy of hypertonic saline nasal irrigation for chronic sinonasal symptoms. Otolaryngol. Head Neck Surg. 2005, 133:3-8.
23. Bunnag C., Leurmarnkul W., Jareoncharsri P., Ungkanont K., Tunsuriyawong P., Kosrirukvongs P. Development of a health-related quality of life questionnaire for Thai Patients with rhinoconjunctivitis. Asian Pac. J. Allergy Immunol. 2004, 22:69-79.
24. Andersen I., Lundqvist G., Jensen P., Philipson K., Proctor D. Nasal clearance in monozygotic twins. Am. Rev. Respir. Dis. 1974, 110:301-305.
25. Juniper E., Howland W., Roberts N., Thompson A., King D. Measuring quality of life in children with rhinoconjunctivitis. J. Allergy Clin. Immunol. 1998, 101:163-170.
26. Cingi C., Unlu H.H., Songu M., Yalcin S., Topcu I., Cakli H., et al. Seawater gel in allergic rhinitis: entrapment effect and mucociliary clearance compared with saline. Ther. Adv. Respir. Dis. 2010, 4(1):13-18.
27. Garavello W., Somigliana E., Acaia B., Gaini L., Pignataro L., Gaini R.M. Nasal lavage in pregnant women with seasonal allergic rhinitis: a randomized study. Int. Arch. Allergy Immunol. 2009, 151(2):137-141.
28. Tamooka L., Murphy C., Davidson T. Clinical study and literature review of nasal irrigation. Laryngoscope 2001, 111:1867-1869.