-
1
-
-
0032545933
-
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
-
Fire, A.; Xu, S.; Montgomery, M. K.; Kostas, S. A.; Driver, S. E.; Mello, C. C. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature, 1998, 391, 806-811.
-
(1998)
Nature
, vol.391
, pp. 806-811
-
-
Fire, A.1
Xu, S.2
Montgomery, M.K.3
Kostas, S.A.4
Driver, S.E.5
Mello, C.C.6
-
2
-
-
33744990135
-
A robust system for RNA interference in the chicken using a modified microRNA operon
-
Das, R. M.; Van Hateren, N. J.; Howell, G. R.; Farrell, E. R.; Bangs, F. K.; Porteous, V. C.; Manning, E. M.; McGrew, M. J.; Ohyama, K.; Sacco, M. A.; Halley, P. A.; Sang, H. M.; Storey, K. G.; Placzek, M.; Tickle, C.; Nair, V. K.; Wilson, S. A. A robust system for RNA interference in the chicken using a modified microRNA operon. Dev. Biol., 2006, 294, 554-563.
-
(2006)
Dev. Biol.
, vol.294
, pp. 554-563
-
-
Das, R.M.1
van Hateren, N.J.2
Howell, G.R.3
Farrell, E.R.4
Bangs, F.K.5
Porteous, V.C.6
Manning, E.M.7
McGrew, M.J.8
Ohyama, K.9
Sacco, M.A.10
Halley, P.A.11
Sang, H.M.12
Storey, K.G.13
Placzek, M.14
Tickle, C.15
Nair, V.K.16
Wilson, S.A.17
-
3
-
-
33845755467
-
Illuminating the silence: Understanding the structure and function of small RNAs
-
Rana, T. M. Illuminating the silence: understanding the structure and function of small RNAs. Nat. Rev. Mol. Cell Biol., 2007, 8, 23-36.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 23-36
-
-
Rana, T.M.1
-
4
-
-
34547626629
-
Promoter-associated RNA is required for RNA-directed transcriptional gene silencing in human cells
-
Han, J.; Kim, D.; Morris, K. V. Promoter-associated RNA is required for RNA-directed transcriptional gene silencing in human cells. Proc. Natl. Acad. Sci. USA, 2007, 104, 12422-12427.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 12422-12427
-
-
Han, J.1
Kim, D.2
Morris, K.V.3
-
5
-
-
34548537573
-
A MicroRNA feedback circuit in midbrain dopamine neurons
-
Kim, J.; Inoue, K.; Ishii, J.; Vanti, W. B.; Voronov, S. V.; Murchison, E.; Hannon, G.; Abeliovich, A. A MicroRNA feedback circuit in midbrain dopamine neurons. Science, 2007, 317, 1220-1224.
-
(2007)
Science
, vol.317
, pp. 1220-1224
-
-
Kim, J.1
Inoue, K.2
Ishii, J.3
Vanti, W.B.4
Voronov, S.V.5
Murchison, E.6
Hannon, G.7
Abeliovich, A.8
-
6
-
-
37648998629
-
Getting to the root of miRNA-mediated gene silencing
-
Eulalio, A.; Huntzinger, E.; Izaurralde, E. Getting to the root of miRNA-mediated gene silencing. Cell, 2008, 132, 9-14.
-
(2008)
Cell
, vol.132
, pp. 9-14
-
-
Eulalio, A.1
Huntzinger, E.2
Izaurralde, E.3
-
7
-
-
61849137222
-
Many roads to maturity: MicroRNA biogenesis pathways and their regulation
-
Winter, J.; Jung, S.; Keller, S.; Gregory, R. I.; Diederichs, S. Many roads to maturity: microRNA biogenesis pathways and their regulation. Nat. Cell Biol., 2009, 11, 228-34.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 228-234
-
-
Winter, J.1
Jung, S.2
Keller, S.3
Gregory, R.I.4
Diederichs, S.5
-
8
-
-
33847036990
-
Strategies for silencing human disease using RNA interference
-
Kim, D. H.; Rossi, J. J. Strategies for silencing human disease using RNA interference. Nat. Rev. Genet, 2007, 8, 173-184.
-
(2007)
Nat. Rev. Genet
, vol.8
, pp. 173-184
-
-
Kim, D.H.1
Rossi, J.J.2
-
9
-
-
34447559636
-
Interfering with disease: A progress report on siRNA-based therapeutics
-
de Fougerolles, A.; Vornlocher, H. P.; Maraganore, J.; Lieberman, J. Interfering with disease: a progress report on siRNA-based therapeutics. Nat. Rev. Drug Discov., 2007, 6, 443-453.
-
(2007)
Nat. Rev. Drug Discov.
, vol.6
, pp. 443-453
-
-
de Fougerolles, A.1
Vornlocher, H.P.2
Maraganore, J.3
Lieberman, J.4
-
10
-
-
11344255740
-
Defining and assaying RNAi in mammalian cells
-
Huppi, K.; Martin, S. E.; Caplen, N. J. Defining and assaying RNAi in mammalian cells. Mol. Cell, 2005, 17, 1-10.
-
(2005)
Mol. Cell
, vol.17
, pp. 1-10
-
-
Huppi, K.1
Martin, S.E.2
Caplen, N.J.3
-
11
-
-
36749026906
-
Switching from repression to activation: MicroRNAs can up-regulate translation
-
Vasudevan, S.; Tong, Y.; Steitz, J. A. Switching from repression to activation: microRNAs can up-regulate translation. Science, 2007, 318, 1931-1934.
-
(2007)
Science
, vol.318
, pp. 1931-1934
-
-
Vasudevan, S.1
Tong, Y.2
Steitz, J.A.3
-
12
-
-
22844440427
-
Identification of hundreds of conserved and nonconserved human microRNAs
-
Bentwich, I.; Avniel, A.; Karov, Y.; Aharonov, R.; Gilad, S.; Barad, O.; Barzilai, A.; Einat, P.; Einav, U.; Meiri, E.; Sharon, E.; Spector, Y.; Bentwich, Z. Identification of hundreds of conserved and nonconserved human microRNAs. Nat. Genet., 2005, 37, 766-770.
-
(2005)
Nat. Genet.
, vol.37
, pp. 766-770
-
-
Bentwich, I.1
Avniel, A.2
Karov, Y.3
Aharonov, R.4
Gilad, S.5
Barad, O.6
Barzilai, A.7
Einat, P.8
Einav, U.9
Meiri, E.10
Sharon, E.11
Spector, Y.12
Bentwich, Z.13
-
13
-
-
33846846397
-
MicroRNA and cancer: Current status and prospective
-
Wu, W.; Sun, M.; Zou, G. M.; Chen, J. MicroRNA and cancer: Current status and prospective. Int. J. Cancer, 2007, 120, 953-60.
-
(2007)
Int. J. Cancer
, vol.120
, pp. 953-960
-
-
Wu, W.1
Sun, M.2
Zou, G.M.3
Chen, J.4
-
14
-
-
11844278458
-
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
-
Lewis, B. P.; Burge, C. B.; Bartel, D. P. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell, 2005, 120, 15-20.
-
(2005)
Cell
, vol.120
, pp. 15-20
-
-
Lewis, B.P.1
Burge, C.B.2
Bartel, D.P.3
-
15
-
-
65749110883
-
Small silencing RNAs: State-of-the-art
-
Grimm, D. Small silencing RNAs: state-of-the-art. Adv. Drug Deliv. Rev., 2009, 61, 672-703.
-
(2009)
Adv. Drug Deliv. Rev.
, vol.61
, pp. 672-703
-
-
Grimm, D.1
-
16
-
-
36849087968
-
Therapeutic application of RNAi: Is mRNA targeting finally ready for prime time?
-
Grimm, D.; Kay, M. A. Therapeutic application of RNAi: is mRNA targeting finally ready for prime time? J. Clin. Invest., 2007, 117, 3633-3641.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 3633-3641
-
-
Grimm, D.1
Kay, M.A.2
-
17
-
-
59349116903
-
Knocking down barriers: Advances in siRNA delivery
-
Whitehead, K. A.; Langer, R.; Anderson, D. G. Knocking down barriers: advances in siRNA delivery. Nat. Rev. Drug Discov., 2009, 8, 129-138.
-
(2009)
Nat. Rev. Drug Discov.
, vol.8
, pp. 129-138
-
-
Whitehead, K.A.1
Langer, R.2
Anderson, D.G.3
-
18
-
-
21044459196
-
Nonviral genetic modification mediates effective transgene expression and functional RNA interference in human mesenchymal stem cells
-
Hoelters, J.; Ciccarella, M.; Drechsel, M.; Geissler, C.; Gulkan, H.; Bocker, W.; Schieker, M.; Jochum, M.; Neth, P. Nonviral genetic modification mediates effective transgene expression and functional RNA interference in human mesenchymal stem cells. J. Gene Med., 2005, 7, 718-728.
-
(2005)
J. Gene Med.
, vol.7
, pp. 718-728
-
-
Hoelters, J.1
Ciccarella, M.2
Drechsel, M.3
Geissler, C.4
Gulkan, H.5
Bocker, W.6
Schieker, M.7
Jochum, M.8
Neth, P.9
-
19
-
-
33751099034
-
RNAi therapeutics: A potential new class of pharmaceutical drugs
-
Bumcrot, D.; Manoharan, M.; Koteliansky, V.; Sah, D. W. RNAi therapeutics: a potential new class of pharmaceutical drugs. Nat. Chem. Biol., 2006, 2, 711-719.
-
(2006)
Nat. Chem. Biol.
, vol.2
, pp. 711-719
-
-
Bumcrot, D.1
Manoharan, M.2
Koteliansky, V.3
Sah, D.W.4
-
20
-
-
13844280638
-
Synthetic shRNAs as potent RNAi triggers
-
Siolas, D.; Lerner, C.; Burchard, J.; Ge, W.; Linsley, P. S.; Paddison, P. J.; Hannon, G. J.; Cleary, M. A. Synthetic shRNAs as potent RNAi triggers. Nat. Biotechnol., 2005, 23, 227-231.
-
(2005)
Nat. Biotechnol.
, vol.23
, pp. 227-231
-
-
Siolas, D.1
Lerner, C.2
Burchard, J.3
Ge, W.4
Linsley, P.S.5
Paddison, P.J.6
Hannon, G.J.7
Cleary, M.A.8
-
21
-
-
33845809231
-
P bodies: At the crossroads of post-transcriptional pathways
-
Eulalio, A.; Behm-Ansmant, I.; Izaurralde, E. P bodies: at the crossroads of post-transcriptional pathways. Nat. Rev. Mol. Cell Biol., 2007, 8, 9-22.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 9-22
-
-
Eulalio, A.1
Behm-Ansmant, I.2
Izaurralde, E.3
-
22
-
-
77951596454
-
Structural basis of binding of P-body-associated proteins GW182 and ataxin-2 by the Mlle domain of poly(A)-binding protein
-
Kozlov, G.; Safaee, N.; Rosenauer, A.; Gehring, K. Structural basis of binding of P-body-associated proteins GW182 and ataxin-2 by the Mlle domain of poly(A)-binding protein. J. Biol. Chem., 2010, 285, 13599-13606.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 13599-13606
-
-
Kozlov, G.1
Safaee, N.2
Rosenauer, A.3
Gehring, K.4
-
23
-
-
77953807575
-
Cytoplasmic ribonucleoprotein (RNP) bodies and their relationship to GW/P bodies
-
Moser, J. J.; Fritzler, M. J. Cytoplasmic ribonucleoprotein (RNP) bodies and their relationship to GW/P bodies. Int. J. Biochem. Cell Biol., 2010, 42, 828-843.
-
(2010)
Int. J. Biochem. Cell Biol.
, vol.42
, pp. 828-843
-
-
Moser, J.J.1
Fritzler, M.J.2
-
24
-
-
4644223259
-
Mechanisms of gene silencing by doublestranded RNA
-
Meister, G.; Tuschl, T. Mechanisms of gene silencing by doublestranded RNA. Nature, 2004, 431, 343-349.
-
(2004)
Nature
, vol.431
, pp. 343-349
-
-
Meister, G.1
Tuschl, T.2
-
25
-
-
2342471249
-
Enhanced gene silencing of HIV-1 specific siRNA using microRNA designed hairpins
-
Boden, D.; Pusch, O.; Silbermann, R.; Lee, F.; Tucker, L.; Ramratnam, B. Enhanced gene silencing of HIV-1 specific siRNA using microRNA designed hairpins. Nucleic Acids Res., 2004, 32, 1154-1158.
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. 1154-1158
-
-
Boden, D.1
Pusch, O.2
Silbermann, R.3
Lee, F.4
Tucker, L.5
Ramratnam, B.6
-
26
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir, S. M.; Harborth, J.; Lendeckel, W.; Yalcin, A.; Weber, K.; Tuschl, T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature, 2001, 411, 494-498.
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
27
-
-
36849026128
-
Applications of RNA interference in mammalian systems
-
Martin, S. E.; Caplen, N. J. Applications of RNA interference in mammalian systems. Annu. Rev. Genom. Hum. Genet., 2007, 8, 81-108.
-
(2007)
Annu. Rev. Genom. Hum. Genet.
, vol.8
, pp. 81-108
-
-
Martin, S.E.1
Caplen, N.J.2
-
28
-
-
25444497200
-
Stable RNA interferencemediated suppression of cyclophilin A diminishes non-small-cell lung tumor growth in vivo
-
Howard, B. A.; Furumai, R.; Campa, M. J.; Rabbani, Z. N.; Vujaskovic, Z.; Wang, X. F.; Patz, E. F., Jr. Stable RNA interferencemediated suppression of cyclophilin A diminishes non-small-cell lung tumor growth in vivo. Cancer Res., 2005, 65, 8853-8860.
-
(2005)
Cancer Res.
, vol.65
, pp. 8853-8860
-
-
Howard, B.A.1
Furumai, R.2
Campa, M.J.3
Rabbani, Z.N.4
Vujaskovic, Z.5
Wang, X.F.6
Patz Jr., E.F.7
-
29
-
-
33645230005
-
Adenovirus-mediated RNA interference against foot-and-mouth disease virus infection both in vitro and in vivo
-
Chen, W.; Liu, M.; Jiao, Y.; Yan, W.; Wei, X.; Chen, J.; Fei, L.; Liu, Y.; Zuo, X.; Yang, F.; Lu, Y.; Zheng, Z. Adenovirus-mediated RNA interference against foot-and-mouth disease virus infection both in vitro and in vivo. J. Virol., 2006, 80, 3559-3566.
-
(2006)
J. Virol.
, vol.80
, pp. 3559-3566
-
-
Chen, W.1
Liu, M.2
Jiao, Y.3
Yan, W.4
Wei, X.5
Chen, J.6
Fei, L.7
Liu, Y.8
Zuo, X.9
Yang, F.10
Lu, Y.11
Zheng, Z.12
-
30
-
-
23844464756
-
RNA interference-mediated virus clearance from cells both acutely and chronically infected with the prototypic arenavirus lymphocytic choriomeningitis virus
-
Sanchez, A. B.; Perez, M.; Cornu, T.; de la Torre, J. C. RNA interference-mediated virus clearance from cells both acutely and chronically infected with the prototypic arenavirus lymphocytic choriomeningitis virus. J. Virol., 2005, 79, 11071-11081.
-
(2005)
J. Virol.
, vol.79
, pp. 11071-11081
-
-
Sanchez, A.B.1
Perez, M.2
Cornu, T.3
de la Torre, J.C.4
-
31
-
-
77951132901
-
Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
-
Davis, M. E.; Zuckerman, J. E.; Choi, C. H.; Seligson, D.; Tolcher, A.; Alabi, C. A.; Yen, Y.; Heidel, J. D.; Ribas, A. Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles. Nature, 2010, 464, 1067-1070.
-
(2010)
Nature
, vol.464
, pp. 1067-1070
-
-
Davis, M.E.1
Zuckerman, J.E.2
Choi, C.H.3
Seligson, D.4
Tolcher, A.5
Alabi, C.A.6
Yen, Y.7
Heidel, J.D.8
Ribas, A.9
-
32
-
-
4644293454
-
Conditionally replicating adenoviruses expressing short hairpin RNAs silence the expression of a target gene in cancer cells
-
Carette, J. E.; Overmeer, R. M.; Schagen, F. H.; Alemany, R.; Barski, O. A.; Gerritsen, W. R.; Van Beusechem, V. W. Conditionally replicating adenoviruses expressing short hairpin RNAs silence the expression of a target gene in cancer cells. Cancer Res., 2004, 64, 2663-2667.
-
(2004)
Cancer Res.
, vol.64
, pp. 2663-2667
-
-
Carette, J.E.1
Overmeer, R.M.2
Schagen, F.H.3
Alemany, R.4
Barski, O.A.5
Gerritsen, W.R.6
van Beusechem, V.W.7
-
33
-
-
12144290519
-
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
-
Calin, G. A.; Sevignani, C.; Dumitru, C. D.; Hyslop, T.; Noch, E.; Yendamuri, S.; Shimizu, M.; Rattan, S.; Bullrich, F.; Negrini, M.; Croce, C. M. Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc. Natl. Acad. Sci. USA, 2004, 101, 2999-3004.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 2999-3004
-
-
Calin, G.A.1
Sevignani, C.2
Dumitru, C.D.3
Hyslop, T.4
Noch, E.5
Yendamuri, S.6
Shimizu, M.7
Rattan, S.8
Bullrich, F.9
Negrini, M.10
Croce, C.M.11
-
34
-
-
33645294070
-
Oncomirs-microRNAs with a role in cancer
-
Esquela-Kerscher, A.; Slack, F. J. Oncomirs-microRNAs with a role in cancer. Nat. Rev. Cancer, 2006, 6, 259-269.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 259-269
-
-
Esquela-Kerscher, A.1
Slack, F.J.2
-
35
-
-
33846188098
-
microRNAs as oncogenes and tumor suppressors
-
Zhang, B.; Pan, X.; Cobb, G. P.; Anderson, T. A. microRNAs as oncogenes and tumor suppressors. Dev. Biol., 2007, 302, 1-12.
-
(2007)
Dev. Biol.
, vol.302
, pp. 1-12
-
-
Zhang, B.1
Pan, X.2
Cobb, G.P.3
Anderson, T.A.4
-
36
-
-
33747876113
-
MicroRNA-cancer connection: The beginning of a new tale
-
Calin, G. A.; Croce, C. M. MicroRNA-cancer connection: the beginning of a new tale. Cancer Res., 2006, 66, 7390-7394.
-
(2006)
Cancer Res.
, vol.66
, pp. 7390-7394
-
-
Calin, G.A.1
Croce, C.M.2
-
37
-
-
18144365478
-
MicroRNA biogenesis and cancer
-
Gregory, R. I.; Shiekhattar, R. MicroRNA biogenesis and cancer. Cancer Res., 2005, 65, 3509-3512.
-
(2005)
Cancer Res.
, vol.65
, pp. 3509-3512
-
-
Gregory, R.I.1
Shiekhattar, R.2
-
38
-
-
20044395613
-
RAS is regulated by the let-7 microRNA family
-
Johnson, S. M.; Grosshans, H.; Shingara, J.; Byrom, M.; Jarvis, R.; Cheng, A.; Labourier, E.; Reinert, K. L.; Brown, D.; Slack, F. J. RAS is regulated by the let-7 microRNA family. Cell, 2005, 120, 635-647.
-
(2005)
Cell
, vol.120
, pp. 635-647
-
-
Johnson, S.M.1
Grosshans, H.2
Shingara, J.3
Byrom, M.4
Jarvis, R.5
Cheng, A.6
Labourier, E.7
Reinert, K.L.8
Brown, D.9
Slack, F.J.10
-
39
-
-
33744768405
-
Inhibition of viruses by RNA interference
-
Stram, Y.; Kuzntzova, L. Inhibition of viruses by RNA interference. Virus Genes., 2006, 32, 299-306.
-
(2006)
Virus Genes.
, vol.32
, pp. 299-306
-
-
Stram, Y.1
Kuzntzova, L.2
-
40
-
-
67249128859
-
The first targeted delivery of siRNA in humans via a self-assembling, cyclodextrin polymer-based nanoparticle: From concept to clinic
-
Davis, M. E. The first targeted delivery of siRNA in humans via a self-assembling, cyclodextrin polymer-based nanoparticle: from concept to clinic. Mol. Pharm., 2009, 6, 659-668.
-
(2009)
Mol. Pharm.
, vol.6
, pp. 659-668
-
-
Davis, M.E.1
-
41
-
-
0035816177
-
Delivery of molecular medicine to solid tumors: Lessons from in vivo imaging of gene expression and function
-
Jain, R. K. Delivery of molecular medicine to solid tumors: lessons from in vivo imaging of gene expression and function. J. Control Release, 2001, 74, 7-25.
-
(2001)
J. Control Release
, vol.74
, pp. 7-25
-
-
Jain, R.K.1
-
42
-
-
33644988908
-
Delivery of viral vectors to tumor cells: Extracellular transport, systemic distribution, and strategies for improvement
-
Wang, Y.; Yuan, F. Delivery of viral vectors to tumor cells: extracellular transport, systemic distribution, and strategies for improvement. Ann. Biomed. Eng., 2006, 34, 114-127.
-
(2006)
Ann. Biomed. Eng.
, vol.34
, pp. 114-127
-
-
Wang, Y.1
Yuan, F.2
-
43
-
-
39749177968
-
Field distribution and DNA transport in solid tumors during electric field-mediated gene delivery
-
Henshaw, J. W.; Yuan, F. Field distribution and DNA transport in solid tumors during electric field-mediated gene delivery. J. Pharm. Sci., 2008, 97, 691-711.
-
(2008)
J. Pharm. Sci.
, vol.97
, pp. 691-711
-
-
Henshaw, J.W.1
Yuan, F.2
-
44
-
-
77951168054
-
Breaking down the barriers: SiRNA delivery and endosome escape
-
Dominska, M.; Dykxhoorn, D. M. Breaking down the barriers: siRNA delivery and endosome escape. J. Cell Sci., 2010, 123, 1183-1189.
-
(2010)
J. Cell Sci.
, vol.123
, pp. 1183-1189
-
-
Dominska, M.1
Dykxhoorn, D.M.2
-
45
-
-
33645519567
-
An efficient intrathecal delivery of small interfering RNA to the spinal cord and peripheral neurons
-
Luo, M. C.; Zhang, D. Q.; Ma, S. W.; Huang, Y. Y.; Shuster, S. J.; Porreca, F.; Lai, J. An efficient intrathecal delivery of small interfering RNA to the spinal cord and peripheral neurons. Mol. Pain., 2005, 1, 29.
-
(2005)
Mol. Pain.
, vol.1
, pp. 29
-
-
Luo, M.C.1
Zhang, D.Q.2
Ma, S.W.3
Huang, Y.Y.4
Shuster, S.J.5
Porreca, F.6
Lai, J.7
-
46
-
-
0031903379
-
Transvascular drug delivery in solid tumors
-
Yuan, F. Transvascular drug delivery in solid tumors. Semin. Radiat. Oncol., 1998, 8, 164-175.
-
(1998)
Semin. Radiat. Oncol.
, vol.8
, pp. 164-175
-
-
Yuan, F.1
-
47
-
-
0028304405
-
Microvascular permeability and interstitial penetration of sterically stabilized (stealth) liposomes in a human tumor xenograft
-
Yuan, F.; Leunig, M.; Huang, S. K.; Berk, D. A.; Papahadjopoulos, D.; Jain, R. K. Microvascular permeability and interstitial penetration of sterically stabilized (stealth) liposomes in a human tumor xenograft. Cancer Res., 1994, 54, 3352-3356.
-
(1994)
Cancer Res.
, vol.54
, pp. 3352-3356
-
-
Yuan, F.1
Leunig, M.2
Huang, S.K.3
Berk, D.A.4
Papahadjopoulos, D.5
Jain, R.K.6
-
48
-
-
0346035742
-
Effects of cell damage and glycosaminoglycan degradation on available extravascular space of different dextrans in a rat fibrosarcoma
-
Krol, A.; Dewhirst, M. W.; Yuan, F. Effects of cell damage and glycosaminoglycan degradation on available extravascular space of different dextrans in a rat fibrosarcoma. Int. J Hyperthermia, 2003, 19, 154-164.
-
(2003)
Int. J Hyperthermia
, vol.19
, pp. 154-164
-
-
Krol, A.1
Dewhirst, M.W.2
Yuan, F.3
-
49
-
-
0033566765
-
Available volume fraction of macromolecules in the extravascular space of a fibrosarcoma: Implications for drug delivery
-
Krol, A.; Maresca, J.; Dewhirst, M. W.; Yuan, F. Available volume fraction of macromolecules in the extravascular space of a fibrosarcoma: implications for drug delivery. Cancer Res., 1999, 59, 4136-4141.
-
(1999)
Cancer Res.
, vol.59
, pp. 4136-4141
-
-
Krol, A.1
Maresca, J.2
Dewhirst, M.W.3
Yuan, F.4
-
50
-
-
0034892565
-
Quantitative analysis of intratumoral infusion of color molecules
-
McGuire, S.; Yuan, F. Quantitative analysis of intratumoral infusion of color molecules. Am. J. Physiol. Heart Circ. Physiol., 2001, 281, H715-721.
-
(2001)
Am. J. Physiol. Heart Circ. Physiol.
, vol.281
-
-
McGuire, S.1
Yuan, F.2
-
51
-
-
0012040121
-
-
In, R. I. Mahato; S. W. Kim, eds.; Taylor & Francis Books: London
-
McGuire, S.; Zaharoff, D.; Yuan, F. In: Pharmaceutical Perspectives of Nucleic Acid-Based Therapeutics, R. I. Mahato; S. W. Kim, eds.; Taylor & Francis Books: London, 2002, pp. 434-454.
-
(2002)
Pharmaceutical Perspectives of Nucleic Acid-Based Therapeutics
, pp. 434-454
-
-
McGuire, S.1
Zaharoff, D.2
Yuan, F.3
-
52
-
-
33746084000
-
Nonlinear dependence of hydraulic conductivity on tissue deformation during intratumoral infusion
-
McGuire, S.; Zaharoff, D.; Yuan, F. Nonlinear dependence of hydraulic conductivity on tissue deformation during intratumoral infusion. Ann. Biomed. Eng., 2006, 34, 1173-1181.
-
(2006)
Ann. Biomed. Eng.
, vol.34
, pp. 1173-1181
-
-
McGuire, S.1
Zaharoff, D.2
Yuan, F.3
-
53
-
-
0035544745
-
Available space and extracellular transport of macromolecules: Effects of pore size and connectedness
-
Yuan, F.; Krol, A.; Tong, S. Available space and extracellular transport of macromolecules: effects of pore size and connectedness. Ann. Biomed. Eng., 2001, 29, 1150-1158.
-
(2001)
Ann. Biomed. Eng.
, vol.29
, pp. 1150-1158
-
-
Yuan, F.1
Krol, A.2
Tong, S.3
-
54
-
-
0031558243
-
Delivery of molecular and cellular medicine to solid tumors
-
Jain, R. K. Delivery of molecular and cellular medicine to solid tumors. Adv. Drug Deliv. Rev., 1997, 26, 71-90.
-
(1997)
Adv. Drug Deliv. Rev.
, vol.26
, pp. 71-90
-
-
Jain, R.K.1
-
55
-
-
0026739369
-
Micropharmacology of monoclonal antibodies in solid tumors: Direct experimental evidence for a binding site barrier
-
Juweid, M.; Neumann, R.; Paik, C.; Perez-Bacete, M. J.; Sato, J.; van Osdol, W.; Weinstein, J. N. Micropharmacology of monoclonal antibodies in solid tumors: direct experimental evidence for a binding site barrier. Cancer Res., 1992, 52, 5144-5153.
-
(1992)
Cancer Res.
, vol.52
, pp. 5144-5153
-
-
Juweid, M.1
Neumann, R.2
Paik, C.3
Perez-Bacete, M.J.4
Sato, J.5
van Osdol, W.6
Weinstein, J.N.7
-
56
-
-
67249122712
-
Biological barriers to therapy with antisense and siRNA oligonucleotides
-
Juliano, R.; Bauman, J.; Kang, H.; Ming, X. Biological barriers to therapy with antisense and siRNA oligonucleotides. Mol. Pharm., 2009, 6, 686-695.
-
(2009)
Mol. Pharm.
, vol.6
, pp. 686-695
-
-
Juliano, R.1
Bauman, J.2
Kang, H.3
Ming, X.4
-
57
-
-
27544477492
-
Intelligent polymers as nonviral vectors
-
Dincer, S.; Turk, M.; Piskin, E. Intelligent polymers as nonviral vectors. Gene. Ther., 2005, 12 (Suppl 1), S139-145.
-
(2005)
Gene. Ther.
, vol.12
, Issue.SUPPL. 1
-
-
Dincer, S.1
Turk, M.2
Piskin, E.3
-
58
-
-
0034913116
-
Nonviral vectors in the new millennium: Delivery barriers in gene transfer
-
Nishikawa, M.; Huang, L. Nonviral vectors in the new millennium: delivery barriers in gene transfer. Hum. Gene. Ther., 2001, 12, 861-870.
-
(2001)
Hum. Gene. Ther.
, vol.12
, pp. 861-870
-
-
Nishikawa, M.1
Huang, L.2
-
59
-
-
0032860574
-
Nuclear targeting peptide scaffolds for lipofection of nondividing mammalian cells
-
Subramanian, A.; Ranganathan, P.; Diamond, S. L. Nuclear targeting peptide scaffolds for lipofection of nondividing mammalian cells. Nat. Biotechnol., 1999, 17, 873-877.
-
(1999)
Nat. Biotechnol.
, vol.17
, pp. 873-877
-
-
Subramanian, A.1
Ranganathan, P.2
Diamond, S.L.3
-
60
-
-
0343067072
-
Endosomes, lysosomes: Their implication in gene transfer
-
Wattiaux, R.; Laurent, N.; Wattiaux-De Coninck, S.; Jadot, M. Endosomes, lysosomes: their implication in gene transfer. Adv. Drug Deliv. Rev., 2000, 41, 201-208.
-
(2000)
Adv. Drug Deliv. Rev.
, vol.41
, pp. 201-208
-
-
Wattiaux, R.1
Laurent, N.2
Wattiaux-de Coninck, S.3
Jadot, M.4
-
61
-
-
0034695472
-
Size-dependent DNA mobility in cytoplasm and nucleus
-
Lukacs, G. L.; Haggie, P.; Seksek, O.; Lechardeur, D.; Freedman, N.; Verkman, A. S. Size-dependent DNA mobility in cytoplasm and nucleus. J. Biol. Chem., 2000, 275, 1625-1629.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 1625-1629
-
-
Lukacs, G.L.1
Haggie, P.2
Seksek, O.3
Lechardeur, D.4
Freedman, N.5
Verkman, A.S.6
-
62
-
-
0029984570
-
Nucleocytoplasmic transport
-
Gorlich, D.; Mattaj, I. W. Nucleocytoplasmic transport. Science, 1996, 271, 1513-1518.
-
(1996)
Science
, vol.271
, pp. 1513-1518
-
-
Gorlich, D.1
Mattaj, I.W.2
-
63
-
-
0030482720
-
Pharmaceutical approach to somatic gene therapy
-
Ledley, F. D. Pharmaceutical approach to somatic gene therapy. Pharm. Res., 1996, 13, 1595-614.
-
(1996)
Pharm. Res.
, vol.13
, pp. 1595-1614
-
-
Ledley, F.D.1
-
64
-
-
0025949412
-
Nuclear targeting sequences--a consensus?
-
Dingwall, C.; Laskey, R. A. Nuclear targeting sequences--a consensus? Trends Biochem. Sci., 1991, 16, 478-481.
-
(1991)
Trends Biochem. Sci.
, vol.16
, pp. 478-481
-
-
Dingwall, C.1
Laskey, R.A.2
-
65
-
-
0038385504
-
RNA interference in mammalian cells by chemically-modified RNA
-
Braasch, D. A.; Jensen, S.; Liu, Y.; Kaur, K.; Arar, K.; White, M. A.; Corey, D. R. RNA interference in mammalian cells by chemically-modified RNA. Biochemistry, 2003, 42, 7967-7975.
-
(2003)
Biochemistry
, vol.42
, pp. 7967-7975
-
-
Braasch, D.A.1
Jensen, S.2
Liu, Y.3
Kaur, K.4
Arar, K.5
White, M.A.6
Corey, D.R.7
-
66
-
-
9144247189
-
Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs
-
Soutschek, J.; Akinc, A.; Bramlage, B.; Charisse, K.; Constien, R.; Donoghue, M.; Elbashir, S.; Geick, A.; Hadwiger, P.; Harborth, J.; John, M.; Kesavan, V.; Lavine, G.; Pandey, R. K.; Racie, T.; Rajeev, K. G.; Rohl, I.; Toudjarska, I.; Wang, G.; Wuschko, S.; Bumcrot, D.; Koteliansky, V.; Limmer, S.; Manoharan, M.; Vornlocher, H. P. Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs. Nature, 2004, 432, 173-178.
-
(2004)
Nature
, vol.432
, pp. 173-178
-
-
Soutschek, J.1
Akinc, A.2
Bramlage, B.3
Charisse, K.4
Constien, R.5
Donoghue, M.6
Elbashir, S.7
Geick, A.8
Hadwiger, P.9
Harborth, J.10
John, M.11
Kesavan, V.12
Lavine, G.13
Pandey, R.K.14
Racie, T.15
Rajeev, K.G.16
Rohl, I.17
Toudjarska, I.18
Wang, G.19
Wuschko, S.20
Bumcrot, D.21
Koteliansky, V.22
Limmer, S.23
Manoharan, M.24
Vornlocher, H.P.25
more..
-
67
-
-
33746931297
-
Ligand-targeted delivery of therapeutic siRNA
-
Ikeda, Y.; Taira, K. Ligand-targeted delivery of therapeutic siRNA. Pharm. Res., 2006, 23, 1631-1640.
-
(2006)
Pharm. Res.
, vol.23
, pp. 1631-1640
-
-
Ikeda, Y.1
Taira, K.2
-
68
-
-
35148815670
-
Mechanisms and optimization of in vivo delivery of lipophilic siRNAs
-
Wolfrum, C.; Shi, S.; Jayaprakash, K. N.; Jayaraman, M.; Wang, G.; Pandey, R. K.; Rajeev, K. G.; Nakayama, T.; Charrise, K.; Ndungo, E. M.; Zimmermann, T.; Koteliansky, V.; Manoharan, M.; Stoffel, M. Mechanisms and optimization of in vivo delivery of lipophilic siRNAs. Nat. Biotechnol., 2007, 25, 1149-1157.
-
(2007)
Nat. Biotechnol.
, vol.25
, pp. 1149-1157
-
-
Wolfrum, C.1
Shi, S.2
Jayaprakash, K.N.3
Jayaraman, M.4
Wang, G.5
Pandey, R.K.6
Rajeev, K.G.7
Nakayama, T.8
Charrise, K.9
Ndungo, E.M.10
Zimmermann, T.11
Koteliansky, V.12
Manoharan, M.13
Stoffel, M.14
-
69
-
-
0032700356
-
Importance of nucleotide sequence and chemical modifications of antisense oligonucleotides
-
Agrawal, S. Importance of nucleotide sequence and chemical modifications of antisense oligonucleotides. Biochim. Biophys. Acta, 1999, 1489, 53-68.
-
(1999)
Biochim. Biophys. Acta
, vol.1489
, pp. 53-68
-
-
Agrawal, S.1
-
70
-
-
3042722268
-
Protein, peptide and nonpeptide drug PEGylation for therapeutic application
-
Pasut, G.; Guiotto, A.; Veronese, F. Protein, peptide and nonpeptide drug PEGylation for therapeutic application. Exp. Opin. Ther. Patents, 2004, 14, 859-894.
-
(2004)
Exp. Opin. Ther. Patents
, vol.14
, pp. 859-894
-
-
Pasut, G.1
Guiotto, A.2
Veronese, F.3
-
71
-
-
33744805790
-
Polymers for gene delivery across length scales
-
Putnam, D. Polymers for gene delivery across length scales. Nat. Mater., 2006, 5, 439-451.
-
(2006)
Nat. Mater.
, vol.5
, pp. 439-451
-
-
Putnam, D.1
-
72
-
-
28744445460
-
Dendrimer biocompatibility and toxicity
-
Duncan, R.; Izzo, L. Dendrimer biocompatibility and toxicity. Adv. Drug Deliv. Rev., 2005, 57, 2215-2237.
-
(2005)
Adv. Drug Deliv. Rev.
, vol.57
, pp. 2215-2237
-
-
Duncan, R.1
Izzo, L.2
-
73
-
-
0037072576
-
Prospects for cationic polymers in gene and oligonucleotide therapy against cancer
-
Merdan, T.; Kopecek, J.; Kissel, T. Prospects for cationic polymers in gene and oligonucleotide therapy against cancer. Adv. Drug Deliv. Rev., 2002, 54, 715-758.
-
(2002)
Adv. Drug Deliv. Rev.
, vol.54
, pp. 715-758
-
-
Merdan, T.1
Kopecek, J.2
Kissel, T.3
-
74
-
-
33745460260
-
Current status of polymeric gene delivery systems
-
Park, T. G.; Jeong, J. H.; Kim, S. W. Current status of polymeric gene delivery systems. Adv. Drug Deliv. Rev., 2006, 58, 467-486.
-
(2006)
Adv. Drug Deliv. Rev.
, vol.58
, pp. 467-486
-
-
Park, T.G.1
Jeong, J.H.2
Kim, S.W.3
-
75
-
-
33745608078
-
Off-target effects by siRNA can induce toxic phenotype
-
Fedorov, Y.; Anderson, E. M.; Birmingham, A.; Reynolds, A.; Karpilow, J.; Robinson, K.; Leake, D.; Marshall, W. S.; Khvorova, A. Off-target effects by siRNA can induce toxic phenotype. RNA, 2006, 12, 1188-1196.
-
(2006)
RNA
, vol.12
, pp. 1188-1196
-
-
Fedorov, Y.1
Anderson, E.M.2
Birmingham, A.3
Reynolds, A.4
Karpilow, J.5
Robinson, K.6
Leake, D.7
Marshall, W.S.8
Khvorova, A.9
-
76
-
-
23944482725
-
RNA interference by mixtures of siRNAs prepared using custom oligonucleotide arrays
-
Oleinikov, A. V.; Zhao, J.; Gray, M. D. RNA interference by mixtures of siRNAs prepared using custom oligonucleotide arrays. Nucleic Acids Res., 2005, 33, e92.
-
(2005)
Nucleic Acids Res.
, vol.33
-
-
Oleinikov, A.V.1
Zhao, J.2
Gray, M.D.3
-
77
-
-
33745299723
-
Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways
-
Grimm, D.; Streetz, K. L.; Jopling, C. L.; Storm, T. A.; Pandey, K.; Davis, C. R.; Marion, P.; Salazar, F.; Kay, M. A. Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways. Nature, 2006, 441, 537-541.
-
(2006)
Nature
, vol.441
, pp. 537-541
-
-
Grimm, D.1
Streetz, K.L.2
Jopling, C.L.3
Storm, T.A.4
Pandey, K.5
Davis, C.R.6
Marion, P.7
Salazar, F.8
Kay, M.A.9
-
78
-
-
33748144763
-
RNA interference as potential therapy--not so fast
-
Marsden, P. A. RNA interference as potential therapy--not so fast. N. Engl. J. Med., 2006, 355, 953-954.
-
(2006)
N. Engl. J. Med.
, vol.355
, pp. 953-954
-
-
Marsden, P.A.1
-
79
-
-
77949446144
-
Cellular toxicity following application of adeno-associated viral vector-mediated RNA interference in the nervous system
-
Ehlert, E. M.; Eggers, R.; Niclou, S. P.; Verhaagen, J. Cellular toxicity following application of adeno-associated viral vector-mediated RNA interference in the nervous system. BMC Neurosci., 2010, 11, 20.
-
(2010)
BMC Neurosci.
, vol.11
, pp. 20
-
-
Ehlert, E.M.1
Eggers, R.2
Niclou, S.P.3
Verhaagen, J.4
-
80
-
-
33746198006
-
Homologous recombination is required for AAV-mediated gene targeting
-
Vasileva, A.; Linden, R. M.; Jessberger, R. Homologous recombination is required for AAV-mediated gene targeting. Nucleic Acids Res., 2006, 34, 3345-3360.
-
(2006)
Nucleic Acids Res.
, vol.34
, pp. 3345-3360
-
-
Vasileva, A.1
Linden, R.M.2
Jessberger, R.3
-
81
-
-
33645762032
-
Suppression of prion protein in livestock by RNA interference
-
Golding, M. C.; Long, C. R.; Carmell, M. A.; Hannon, G. J.; Westhusin, M. E. Suppression of prion protein in livestock by RNA interference. Proc. Natl. Acad. Sci. USA, 2006, 103, 5285-5290.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 5285-5290
-
-
Golding, M.C.1
Long, C.R.2
Carmell, M.A.3
Hannon, G.J.4
Westhusin, M.E.5
-
82
-
-
0035030198
-
Delivery systems intended for in vivo gene therapy of cancer: Targeting and replication competent viral vectors
-
Galanis, E.; Vile, R.; Russell, S. J. Delivery systems intended for in vivo gene therapy of cancer: targeting and replication competent viral vectors. Crit. Rev. Oncol. Hematol., 2001, 38, 177-192.
-
(2001)
Crit. Rev. Oncol. Hematol.
, vol.38
, pp. 177-192
-
-
Galanis, E.1
Vile, R.2
Russell, S.J.3
-
83
-
-
0034089010
-
Viral vectors for gene delivery and gene therapy within the endocrine system
-
Stone, D.; David, A.; Bolognani, F.; Lowenstein, P. R.; Castro, M. G. Viral vectors for gene delivery and gene therapy within the endocrine system. J. Endocrinol., 2000, 164, 103-118.
-
(2000)
J. Endocrinol.
, vol.164
, pp. 103-118
-
-
Stone, D.1
David, A.2
Bolognani, F.3
Lowenstein, P.R.4
Castro, M.G.5
-
84
-
-
31144475398
-
Viral gene therapy strategies: From basic science to clinical application
-
Young, L. S.; Searle, P. F.; Onion, D.; Mautner, V. Viral gene therapy strategies: from basic science to clinical application. J. Pathol., 2006, 208, 299-318.
-
(2006)
J. Pathol.
, vol.208
, pp. 299-318
-
-
Young, L.S.1
Searle, P.F.2
Onion, D.3
Mautner, V.4
-
85
-
-
22444449204
-
Nonviral gene transfer to skeletal, smooth, and cardiac muscle in living animals
-
Dean, D. A. Nonviral gene transfer to skeletal, smooth, and cardiac muscle in living animals. Am. J. Physiol. Cell Physiol., 2005, 289, C233-245.
-
(2005)
Am. J. Physiol. Cell Physiol.
, vol.289
-
-
Dean, D.A.1
-
86
-
-
67249096677
-
Nonviral methods for siRNA delivery
-
Gao, K.; Huang, L. Nonviral methods for siRNA delivery. Mol. Pharm., 2009, 6, 651-658.
-
(2009)
Mol. Pharm.
, vol.6
, pp. 651-658
-
-
Gao, K.1
Huang, L.2
-
87
-
-
77349095284
-
Polyethylenimine/small interfering RNA-mediated knockdown of vascular endothelial growth factor in vivo exerts anti-tumor effects synergistically with Bevacizumab
-
Hobel, S.; Koburger, I.; John, M.; Czubayko, F.; Hadwiger, P.; Vornlocher, H. P.; Aigner, A. Polyethylenimine/small interfering RNA-mediated knockdown of vascular endothelial growth factor in vivo exerts anti-tumor effects synergistically with Bevacizumab. J. Gene. Med., 2010, 12, 287-300.
-
(2010)
J. Gene. Med.
, vol.12
, pp. 287-300
-
-
Hobel, S.1
Koburger, I.2
John, M.3
Czubayko, F.4
Hadwiger, P.5
Vornlocher, H.P.6
Aigner, A.7
-
88
-
-
31444444636
-
RNA interference in immune cells by use of osmotic delivery of siRNA
-
Aoki, M.; Ishii, T.; Kanaoka, M.; Kimura, T. RNA interference in immune cells by use of osmotic delivery of siRNA. Biochem. Biophys. Res. Commun., 2006, 341, 326-333.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.341
, pp. 326-333
-
-
Aoki, M.1
Ishii, T.2
Kanaoka, M.3
Kimura, T.4
-
89
-
-
15044354554
-
RNAi-induced gene silencing by local electroporation in targeting brain region
-
Akaneya, Y.; Jiang, B.; Tsumoto, T. RNAi-induced gene silencing by local electroporation in targeting brain region. J. Neurophysiol., 2005, 93, 594-602.
-
(2005)
J. Neurophysiol.
, vol.93
, pp. 594-602
-
-
Akaneya, Y.1
Jiang, B.2
Tsumoto, T.3
-
90
-
-
33745607931
-
Microtargeted gene silencing and ectopic expression in live embryos using biolistic delivery with a pneumatic capillary gun
-
Shefi, O.; Simonnet, C.; Baker, M. W.; Glass, J. R.; Macagno, E. R.; Groisman, A. Microtargeted gene silencing and ectopic expression in live embryos using biolistic delivery with a pneumatic capillary gun. J. Neurosci., 2006, 26, 6119-6123.
-
(2006)
J. Neurosci.
, vol.26
, pp. 6119-6123
-
-
Shefi, O.1
Simonnet, C.2
Baker, M.W.3
Glass, J.R.4
Macagno, E.R.5
Groisman, A.6
-
91
-
-
70350348495
-
Novel ultrasound-targeted microbubble destruction mediated short hairpin RNA plasmid transfection targeting survivin inhibits gene expression and induces apoptosis of HeLa cells
-
Chen, Z.; Liang, K.; Xie, M.; Wang, X.; Lu, Q.; Zhang, J. Novel ultrasound-targeted microbubble destruction mediated short hairpin RNA plasmid transfection targeting survivin inhibits gene expression and induces apoptosis of HeLa cells. Mol. Biol. Rep., 2009, 36, 2059-2067.
-
(2009)
Mol. Biol. Rep.
, vol.36
, pp. 2059-2067
-
-
Chen, Z.1
Liang, K.2
Xie, M.3
Wang, X.4
Lu, Q.5
Zhang, J.6
-
92
-
-
23744513822
-
A novel method for the intracellular delivery of siRNA using microbubble-enhanced focused ultrasound
-
Kinoshita, M.; Hynynen, K. A novel method for the intracellular delivery of siRNA using microbubble-enhanced focused ultrasound. Biochem. Biophys. Res. Commun., 2005, 335, 393-399.
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.335
, pp. 393-399
-
-
Kinoshita, M.1
Hynynen, K.2
-
93
-
-
33745907268
-
RNAi-mediated silencing of estrogen receptor {alpha} in the ventromedial nucleus of hypothalamus abolishes female sexual behaviors
-
Musatov, S.; Chen, W.; Pfaff, D. W.; Kaplitt, M. G.; Ogawa, S. RNAi-mediated silencing of estrogen receptor {alpha} in the ventromedial nucleus of hypothalamus abolishes female sexual behaviors. Proc. Natl. Acad. Sci. USA, 2006, 103, 10456-10460.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 10456-10460
-
-
Musatov, S.1
Chen, W.2
Pfaff, D.W.3
Kaplitt, M.G.4
Ogawa, S.5
-
94
-
-
70149112527
-
Retroviral delivery of RNA interference against Marek's disease virus in vivo
-
Chen, M.; Payne, W. S.; Dunn, J. R.; Chang, S.; Zhang, H. M.; Hunt, H. D.; Dodgson, J. B. Retroviral delivery of RNA interference against Marek's disease virus in vivo. Poult Sci., 2009, 88, 1373-1380.
-
(2009)
Poult Sci.
, vol.88
, pp. 1373-1380
-
-
Chen, M.1
Payne, W.S.2
Dunn, J.R.3
Chang, S.4
Zhang, H.M.5
Hunt, H.D.6
Dodgson, J.B.7
-
95
-
-
59449083718
-
Sustained long-term RNA interference in nucleus pulposus cells in vivo mediated by unmodified small interfering RNA
-
Suzuki, T.; Nishida, K.; Kakutani, K.; Maeno, K.; Yurube, T.; Takada, T.; Kurosaka, M.; Doita, M. Sustained long-term RNA interference in nucleus pulposus cells in vivo mediated by unmodified small interfering RNA. Eur. Spine J., 2009, 18, 263-270.
-
(2009)
Eur. Spine J.
, vol.18
, pp. 263-270
-
-
Suzuki, T.1
Nishida, K.2
Kakutani, K.3
Maeno, K.4
Yurube, T.5
Takada, T.6
Kurosaka, M.7
Doita, M.8
-
96
-
-
33845873577
-
Cellular delivery of small interfering RNA by a non-covalently attached cellpenetrating peptide: Quantitative analysis of uptake and biological effect
-
Veldhoen, S.; Laufer, S. D.; Trampe, A.; Restle, T. Cellular delivery of small interfering RNA by a non-covalently attached cellpenetrating peptide: quantitative analysis of uptake and biological effect. Nucleic Acids Res., 2006, 34, 6561-6573.
-
(2006)
Nucleic Acids Res.
, vol.34
, pp. 6561-6573
-
-
Veldhoen, S.1
Laufer, S.D.2
Trampe, A.3
Restle, T.4
-
97
-
-
67149093390
-
Efficient siRNA delivery into primary cells by a peptide transduction domain-dsRNA binding domain fusion protein
-
Eguchi, A.; Meade, B. R.; Chang, Y. C.; Fredrickson, C. T.; Willert, K.; Puri, N.; Dowdy, S. F. Efficient siRNA delivery into primary cells by a peptide transduction domain-dsRNA binding domain fusion protein. Nat. Biotechnol., 2009, 27, 567-571.
-
(2009)
Nat. Biotechnol.
, vol.27
, pp. 567-571
-
-
Eguchi, A.1
Meade, B.R.2
Chang, Y.C.3
Fredrickson, C.T.4
Willert, K.5
Puri, N.6
Dowdy, S.F.7
-
98
-
-
33845679807
-
Surface-modified LPD nanoparticles for tumor targeting
-
Li, S. D.; Huang, L. Surface-modified LPD nanoparticles for tumor targeting. Ann. N. Y. Acad. Sci., 2006, 1082, 1-8.
-
(2006)
Ann. N. Y. Acad. Sci.
, vol.1082
, pp. 1-8
-
-
Li, S.D.1
Huang, L.2
-
99
-
-
33845248415
-
Smart PEGylated gold nanoparticles for the cytoplasmic delivery of siRNA to induce enhanced gene silencing
-
Oishi, M.; Nakaogami, J.; Ishii, T.; Nagasaki, Y. Smart PEGylated gold nanoparticles for the cytoplasmic delivery of siRNA to induce enhanced gene silencing. Chem. Lett., 2006, 35, 1046-1047.
-
(2006)
Chem. Lett.
, vol.35
, pp. 1046-1047
-
-
Oishi, M.1
Nakaogami, J.2
Ishii, T.3
Nagasaki, Y.4
-
100
-
-
33745630675
-
Stearylated octaarginine and artificial virus-like particles for transfection of siRNA into primary rat neurons
-
Tönges, L.; Lingor, P.; Egle, R.; Dietz, G. P.; Fahr, A.; Bahr, M. Stearylated octaarginine and artificial virus-like particles for transfection of siRNA into primary rat neurons. RNA, 2006, 12, 1431-1438.
-
(2006)
RNA
, vol.12
, pp. 1431-1438
-
-
Tönges, L.1
Lingor, P.2
Egle, R.3
Dietz, G.P.4
Fahr, A.5
Bahr, M.6
-
101
-
-
26444497548
-
Single small-interfering RNA expression vector for silencing multiple transforming growth factor-beta pathway components
-
Jazag, A.; Kanai, F.; Ijichi, H.; Tateishi, K.; Ikenoue, T.; Tanaka, Y.; Ohta, M.; Imamura, J.; Guleng, B.; Asaoka, Y.; Kawabe, T.; Miyagishi, M.; Taira, K.; Omata, M. Single small-interfering RNA expression vector for silencing multiple transforming growth factor-beta pathway components. Nucleic Acids Res., 2005, 33, e131.
-
(2005)
Nucleic Acids Res.
, vol.33
-
-
Jazag, A.1
Kanai, F.2
Ijichi, H.3
Tateishi, K.4
Ikenoue, T.5
Tanaka, Y.6
Ohta, M.7
Imamura, J.8
Guleng, B.9
Asaoka, Y.10
Kawabe, T.11
Miyagishi, M.12
Taira, K.13
Omata, M.14
-
102
-
-
49349115993
-
RNAi-mediated reversible opening of the bloodbrain barrier
-
Campbell, M.; Kiang, A. S.; Kenna, P. F.; Kerskens, C.; Blau, C.; O'Dwyer, L.; Tivnan, A.; Kelly, J. A.; Brankin, B.; Farrar, G. J.; Humphries, P. RNAi-mediated reversible opening of the bloodbrain barrier. J. Gene. Med., 2008, 10, 930-947.
-
(2008)
J. Gene. Med.
, vol.10
, pp. 930-947
-
-
Campbell, M.1
Kiang, A.S.2
Kenna, P.F.3
Kerskens, C.4
Blau, C.5
O'Dwyer, L.6
Tivnan, A.7
Kelly, J.A.8
Brankin, B.9
Farrar, G.J.10
Humphries, P.11
-
103
-
-
33846929162
-
Therapeutic RNA interference of malignant melanoma by electrotransfer of small interfering RNA targeting Mitf
-
Nakai, N.; Kishida, T.; Shin-Ya, M.; Imanishi, J.; Ueda, Y.; Kishimoto, S.; Mazda, O. Therapeutic RNA interference of malignant melanoma by electrotransfer of small interfering RNA targeting Mitf. Gene. Ther., 2007, 14, 357-365.
-
(2007)
Gene. Ther.
, vol.14
, pp. 357-365
-
-
Nakai, N.1
Kishida, T.2
Shin-Ya, M.3
Imanishi, J.4
Ueda, Y.5
Kishimoto, S.6
Mazda, O.7
-
104
-
-
33644659341
-
A plasmid-encoded VEGF siRNA reduces glioblastoma angiogenesis and its combination with interleukin-4 blocks tumor growth in a xenograft mouse model
-
Niola, F.; Evangelisti, C.; Campagnolo, L.; Massalini, S.; Bue, M. C.; Mangiola, A.; Masotti, A.; Maira, G.; Farace, M. G.; Ciafre, S. A. A plasmid-encoded VEGF siRNA reduces glioblastoma angiogenesis and its combination with interleukin-4 blocks tumor growth in a xenograft mouse model. Cancer Biol. Ther., 2006, 5, 174-179.
-
(2006)
Cancer Biol. Ther.
, vol.5
, pp. 174-179
-
-
Niola, F.1
Evangelisti, C.2
Campagnolo, L.3
Massalini, S.4
Bue, M.C.5
Mangiola, A.6
Masotti, A.7
Maira, G.8
Farace, M.G.9
Ciafre, S.A.10
-
105
-
-
2442668068
-
A small interfering RNA targeting vascular endothelial growth factor as cancer therapeutics
-
Takei, Y.; Kadomatsu, K.; Yuzawa, Y.; Matsuo, S.; Muramatsu, T. A small interfering RNA targeting vascular endothelial growth factor as cancer therapeutics. Cancer Res., 2004, 64, 3365-3370.
-
(2004)
Cancer Res.
, vol.64
, pp. 3365-3370
-
-
Takei, Y.1
Kadomatsu, K.2
Yuzawa, Y.3
Matsuo, S.4
Muramatsu, T.5
-
106
-
-
33646921719
-
Lentivirus-mediated RNA interference therapy for human immunodeficiency virus type 1 infection
-
Morris, K. V.; Rossi, J. J. Lentivirus-mediated RNA interference therapy for human immunodeficiency virus type 1 infection. Hum. Gene Ther., 2006, 17, 479-486.
-
(2006)
Hum. Gene Ther.
, vol.17
, pp. 479-486
-
-
Morris, K.V.1
Rossi, J.J.2
-
107
-
-
33646097693
-
Knockdown of apolipoprotein B, an atherogenic apolipoprotein, in HepG2 cells by lentivirus-mediated siRNA
-
Liao, W.; Ning, G. Knockdown of apolipoprotein B, an atherogenic apolipoprotein, in HepG2 cells by lentivirus-mediated siRNA. Biochem. Biophys. Res. Commun., 2006, 344, 478-483.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.344
, pp. 478-483
-
-
Liao, W.1
Ning, G.2
-
108
-
-
5444250395
-
Retroviral vectors: New applications for an old tool
-
Barquinero, J.; Eixarch, H.; Perez-Melgosa, M. Retroviral vectors: new applications for an old tool. Gene Ther., 2004, 11 (Suppl 1), S3-9.
-
(2004)
Gene Ther.
, vol.11
, Issue.SUPPL. 1
-
-
Barquinero, J.1
Eixarch, H.2
Perez-Melgosa, M.3
-
109
-
-
27844611450
-
Efficient gene transfer into silkworm larval tissues by a combination of sonoporation and lipofection
-
Lee, J. M.; Takahashi, M.; Mon, H.; Koga, K.; Kawaguchi, Y.; Kusakabe, T. Efficient gene transfer into silkworm larval tissues by a combination of sonoporation and lipofection. Cell Biol. Int., 2005, 29, 976-979.
-
(2005)
Cell Biol. Int.
, vol.29
, pp. 976-979
-
-
Lee, J.M.1
Takahashi, M.2
Mon, H.3
Koga, K.4
Kawaguchi, Y.5
Kusakabe, T.6
-
110
-
-
4344608398
-
An adenovirus vector for efficient RNA interferencemediated suppression of target genes in insulinoma cells and pancreatic islets of langerhans
-
Bain, J. R.; Schisler, J. C.; Takeuchi, K.; Newgard, C. B.; Becker, T. C. An adenovirus vector for efficient RNA interferencemediated suppression of target genes in insulinoma cells and pancreatic islets of langerhans. Diabetes, 2004, 53, 2190-2194.
-
(2004)
Diabetes
, vol.53
, pp. 2190-2194
-
-
Bain, J.R.1
Schisler, J.C.2
Takeuchi, K.3
Newgard, C.B.4
Becker, T.C.5
-
111
-
-
33644806765
-
Knockdown of human p53 gene expression in 293-T cells by retroviral vector-mediated short hairpin RNA
-
Hao, D. L.; Liu, C. M.; Dong, W. J.; Gong, H.; Wu, X. S.; Liu, D. P.; Liang, C. C. Knockdown of human p53 gene expression in 293-T cells by retroviral vector-mediated short hairpin RNA. Acta. Biochim. Biophys. Sin (Shanghai), 2005, 37, 779-783.
-
(2005)
Acta. Biochim. Biophys. Sin (Shanghai)
, vol.37
, pp. 779-783
-
-
Hao, D.L.1
Liu, C.M.2
Dong, W.J.3
Gong, H.4
Wu, X.S.5
Liu, D.P.6
Liang, C.C.7
-
112
-
-
3843087480
-
Retrovirally mediated RNA interference targeting the M2 subunit of ribonucleotide reductase: A novel therapeutic strategy in pancreatic cancer
-
Duxbury, M. S.; Ito, H.; Benoit, E.; Zinner, M. J.; Ashley, S. W.; Whang, E. E. Retrovirally mediated RNA interference targeting the M2 subunit of ribonucleotide reductase: A novel therapeutic strategy in pancreatic cancer. Surgery, 2004, 136, 261-269.
-
(2004)
Surgery
, vol.136
, pp. 261-269
-
-
Duxbury, M.S.1
Ito, H.2
Benoit, E.3
Zinner, M.J.4
Ashley, S.W.5
Whang, E.E.6
-
113
-
-
33645009966
-
Control of small inhibitory RNA levels and RNA interference by doxycycline induced activation of a minimal RNA polymerase III promoter
-
Amar, L.; Desclaux, M.; Faucon-Biguet, N.; Mallet, J.; Vogel, R. Control of small inhibitory RNA levels and RNA interference by doxycycline induced activation of a minimal RNA polymerase III promoter. Nucleic Acids Res., 2006, 34, e37.
-
(2006)
Nucleic Acids Res.
, vol.34
-
-
Amar, L.1
Desclaux, M.2
Faucon-Biguet, N.3
Mallet, J.4
Vogel, R.5
-
114
-
-
5444275097
-
Immune responses to gene therapy vectors: Influence on vector function and effector mechanisms
-
Bessis, N.; GarciaCozar, F. J.; Boissier, M. C. Immune responses to gene therapy vectors: influence on vector function and effector mechanisms. Gene. Ther., 2004, 11 (Suppl 1), S10-17.
-
(2004)
Gene. Ther.
, vol.11
, Issue.SUPPL. 1
-
-
Bessis, N.1
Garcia Cozar, F.J.2
Boissier, M.C.3
-
115
-
-
33645104092
-
rAAV-mediated shRNA ameliorated neuropathology in Huntington disease model mouse
-
Machida, Y.; Okada, T.; Kurosawa, M.; Oyama, F.; Ozawa, K.; Nukina, N. rAAV-mediated shRNA ameliorated neuropathology in Huntington disease model mouse. Biochem. Biophys. Res. Commun., 2006, 343, 190-197.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.343
, pp. 190-197
-
-
Machida, Y.1
Okada, T.2
Kurosawa, M.3
Oyama, F.4
Ozawa, K.5
Nukina, N.6
-
116
-
-
63649117394
-
Long-term cardiac-targeted RNA interference for the treatment of heart failure restores cardiac function and reduces pathological hypertrophy
-
Suckau, L.; Fechner, H.; Chemaly, E.; Krohn, S.; Hadri, L.; Kockskamper, J.; Westermann, D.; Bisping, E.; Ly, H.; Wang, X.; Kawase, Y.; Chen, J.; Liang, L.; Sipo, I.; Vetter, R.; Weger, S.; Kurreck, J.; Erdmann, V.; Tschope, C.; Pieske, B.; Lebeche, D.; Schultheiss, H. P.; Hajjar, R. J.; Poller, W. C. Long-term cardiac-targeted RNA interference for the treatment of heart failure restores cardiac function and reduces pathological hypertrophy. Circulation, 2009, 119, 1241-1252.
-
(2009)
Circulation
, vol.119
, pp. 1241-1252
-
-
Suckau, L.1
Fechner, H.2
Chemaly, E.3
Krohn, S.4
Hadri, L.5
Kockskamper, J.6
Westermann, D.7
Bisping, E.8
Ly, H.9
Wang, X.10
Kawase, Y.11
Chen, J.12
Liang, L.13
Sipo, I.14
Vetter, R.15
Weger, S.16
Kurreck, J.17
Erdmann, V.18
Tschope, C.19
Pieske, B.20
Lebeche, D.21
Schultheiss, H.P.22
Hajjar, R.J.23
Poller, W.C.24
more..
-
117
-
-
57149115125
-
Targeting Marek's disease virus by RNA interference delivered from a herpesvirus vaccine
-
Lambeth, L. S.; Zhao, Y.; Smith, L. P.; Kgosana, L.; Nair, V. Targeting Marek's disease virus by RNA interference delivered from a herpesvirus vaccine. Vaccine, 2009, 27, 298-306.
-
(2009)
Vaccine
, vol.27
, pp. 298-306
-
-
Lambeth, L.S.1
Zhao, Y.2
Smith, L.P.3
Kgosana, L.4
Nair, V.5
-
118
-
-
2342481718
-
New non-viral method for gene transfer into primary cells
-
Gresch, O.; Engel, F. B.; Nesic, D.; Tran, T. T.; England, H. M.; Hickman, E. S.; Korner, I.; Gan, L.; Chen, S.; Castro-Obregon, S.; Hammermann, R.; Wolf, J.; Muller-Hartmann, H.; Nix, M.; Siebenkotten, G.; Kraus, G.; Lun, K. New non-viral method for gene transfer into primary cells. Methods, 2004, 33, 151-163.
-
(2004)
Methods
, vol.33
, pp. 151-163
-
-
Gresch, O.1
Engel, F.B.2
Nesic, D.3
Tran, T.T.4
England, H.M.5
Hickman, E.S.6
Korner, I.7
Gan, L.8
Chen, S.9
Castro-Obregon, S.10
Hammermann, R.11
Wolf, J.12
Muller-Hartmann, H.13
Nix, M.14
Siebenkotten, G.15
Kraus, G.16
Lun, K.17
-
119
-
-
13444262170
-
Inhibition of respiratory viruses by nasally administered siRNA
-
Bitko, V.; Musiyenko, A.; Shulyayeva, O.; Barik, S. Inhibition of respiratory viruses by nasally administered siRNA. Nat. Med., 2005, 11, 50-55.
-
(2005)
Nat. Med.
, vol.11
, pp. 50-55
-
-
Bitko, V.1
Musiyenko, A.2
Shulyayeva, O.3
Barik, S.4
-
120
-
-
33748054817
-
RNA interference in vitro and in vivo using a novel chitosan/siRNA nanoparticle system
-
Howard, K. A.; Rahbek, U. L.; Liu, X.; Damgaard, C. K.; Glud, S. Z.; Andersen, M. O.; Hovgaard, M. B.; Schmitz, A.; Nyengaard, J. R.; Besenbacher, F.; Kjems, J. RNA interference in vitro and in vivo using a novel chitosan/siRNA nanoparticle system. Mol. Ther., 2006, 14, 476-484.
-
(2006)
Mol. Ther.
, vol.14
, pp. 476-484
-
-
Howard, K.A.1
Rahbek, U.L.2
Liu, X.3
Damgaard, C.K.4
Glud, S.Z.5
Andersen, M.O.6
Hovgaard, M.B.7
Schmitz, A.8
Nyengaard, J.R.9
Besenbacher, F.10
Kjems, J.11
-
121
-
-
33746581992
-
Delivery systems for the direct application of siRNAs to induce RNA interference (RNAi) in vivo
-
Aigner, A. Delivery systems for the direct application of siRNAs to induce RNA interference (RNAi) in vivo. J. Biomed. Biotechnol., 2006, 2006, 71659.
-
(2006)
J. Biomed. Biotechnol.
, vol.2006
, pp. 71659
-
-
Aigner, A.1
-
122
-
-
15444373116
-
RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo
-
Urban-Klein, B.; Werth, S.; Abuharbeid, S.; Czubayko, F.; Aigner, A. RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivo. Gene. Ther., 2005, 12, 461-466.
-
(2005)
Gene. Ther.
, vol.12
, pp. 461-466
-
-
Urban-Klein, B.1
Werth, S.2
Abuharbeid, S.3
Czubayko, F.4
Aigner, A.5
-
123
-
-
33751218547
-
Therapeutic peptides: Technological advances driving peptides into development
-
Sato, A. K.; Viswanathan, M.; Kent, R. B.; Wood, C. R. Therapeutic peptides: technological advances driving peptides into development. Curr. Opin. Biotechnol., 2006, 17, 638-642.
-
(2006)
Curr. Opin. Biotechnol.
, vol.17
, pp. 638-642
-
-
Sato, A.K.1
Viswanathan, M.2
Kent, R.B.3
Wood, C.R.4
-
124
-
-
4344651353
-
Visualizing a correlation between siRNA localization, cellular uptake, and RNAi in living cells
-
Chiu, Y. L.; Ali, A.; Chu, C. Y.; Cao, H.; Rana, T. M. Visualizing a correlation between siRNA localization, cellular uptake, and RNAi in living cells. Chem. Biol., 2004, 11, 1165-1175.
-
(2004)
Chem. Biol.
, vol.11
, pp. 1165-1175
-
-
Chiu, Y.L.1
Ali, A.2
Chu, C.Y.3
Cao, H.4
Rana, T.M.5
-
125
-
-
34447114618
-
Transvascular delivery of small interfering RNA to the central nervous system
-
Kumar, P.; Wu, H.; McBride, J. L.; Jung, K. E.; Kim, M. H.; Davidson, B. L.; Lee, S. K.; Shankar, P.; Manjunath, N. Transvascular delivery of small interfering RNA to the central nervous system. Nature, 2007, 448, 39-43.
-
(2007)
Nature
, vol.448
, pp. 39-43
-
-
Kumar, P.1
Wu, H.2
McBride, J.L.3
Jung, K.E.4
Kim, M.H.5
Davidson, B.L.6
Lee, S.K.7
Shankar, P.8
Manjunath, N.9
-
126
-
-
23844474160
-
Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors
-
Song, E.; Zhu, P.; Lee, S. K.; Chowdhury, D.; Kussman, S.; Dykxhoorn, D. M.; Feng, Y.; Palliser, D.; Weiner, D. B.; Shankar, P.; Marasco, W. A.; Lieberman, J. Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors. Nat. Biotechnol., 2005, 23, 709-717.
-
(2005)
Nat. Biotechnol.
, vol.23
, pp. 709-717
-
-
Song, E.1
Zhu, P.2
Lee, S.K.3
Chowdhury, D.4
Kussman, S.5
Dykxhoorn, D.M.6
Feng, Y.7
Palliser, D.8
Weiner, D.B.9
Shankar, P.10
Marasco, W.A.11
Lieberman, J.12
-
127
-
-
33747031960
-
Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras
-
McNamara, J. O., 2nd; Andrechek, E. R.; Wang, Y.; Viles, K. D.; Rempel, R. E.; Gilboa, E.; Sullenger, B. A.; Giangrande, P. H. Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras. Nat. Biotechnol., 2006, 24, 1005-1015.
-
(2006)
Nat. Biotechnol.
, vol.24
, pp. 1005-1015
-
-
McNamara II, J.O.1
Andrechek, E.R.2
Wang, Y.3
Viles, K.D.4
Rempel, R.E.5
Gilboa, E.6
Sullenger, B.A.7
Giangrande, P.H.8
-
128
-
-
49549117077
-
T cellspecific siRNA delivery suppresses HIV-1 infection in humanized mice
-
Kumar, P.; Ban, H. S.; Kim, S. S.; Wu, H.; Pearson, T.; Greiner, D. L.; Laouar, A.; Yao, J.; Haridas, V.; Habiro, K.; Yang, Y. G.; Jeong, J. H.; Lee, K. Y.; Kim, Y. H.; Kim, S. W.; Peipp, M.; Fey, G. H.; Manjunath, N.; Shultz, L. D.; Lee, S. K.; Shankar, P. T cellspecific siRNA delivery suppresses HIV-1 infection in humanized mice. Cell, 2008, 134, 577-586.
-
(2008)
Cell
, vol.134
, pp. 577-586
-
-
Kumar, P.1
Ban, H.S.2
Kim, S.S.3
Wu, H.4
Pearson, T.5
Greiner, D.L.6
Laouar, A.7
Yao, J.8
Haridas, V.9
Habiro, K.10
Yang, Y.G.11
Jeong, J.H.12
Lee, K.Y.13
Kim, Y.H.14
Kim, S.W.15
Peipp, M.16
Fey, G.H.17
Manjunath, N.18
Shultz, L.D.19
Lee, S.K.20
Shankar, P.21
more..
-
129
-
-
14944376721
-
Healing sound: The use of ultrasound in drug delivery and other therapeutic applications
-
Mitragotri, S. Healing sound: the use of ultrasound in drug delivery and other therapeutic applications. Nat. Rev. Drug Discov., 2005, 4, 255-260.
-
(2005)
Nat. Rev. Drug Discov.
, vol.4
, pp. 255-260
-
-
Mitragotri, S.1
-
130
-
-
58149518087
-
Activation of transgene expression in skeletal muscle by focused ultrasound
-
Lu, X.; Sankin, G.; Pua, E. C.; Madden, J.; Zhong, P. Activation of transgene expression in skeletal muscle by focused ultrasound. Biochem. Biophys. Res. Commun., 2009, 379, 428-433.
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.379
, pp. 428-433
-
-
Lu, X.1
Sankin, G.2
Pua, E.C.3
Madden, J.4
Zhong, P.5
-
131
-
-
2342466782
-
Physical parameters influencing optimization of ultrasound-mediated DNA transfection
-
Zarnitsyn, V. G.; Prausnitz, M. R. Physical parameters influencing optimization of ultrasound-mediated DNA transfection. Ultrasound Med. Biol., 2004, 30, 527-538.
-
(2004)
Ultrasound Med. Biol.
, vol.30
, pp. 527-538
-
-
Zarnitsyn, V.G.1
Prausnitz, M.R.2
-
132
-
-
24344442393
-
Sonoporation using microbubble BR14 promotes pDNA/siRNA transduction to murine heart
-
Tsunoda, S.; Mazda, O.; Oda, Y.; Iida, Y.; Akabame, S.; Kishida, T.; Shin-Ya, M.; Asada, H.; Gojo, S.; Imanishi, J.; Matsubara, H.; Yoshikawa, T. Sonoporation using microbubble BR14 promotes pDNA/siRNA transduction to murine heart. Biochem. Biophys. Res. Commun., 2005, 336, 118-127.
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.336
, pp. 118-127
-
-
Tsunoda, S.1
Mazda, O.2
Oda, Y.3
Iida, Y.4
Akabame, S.5
Kishida, T.6
Shin-Ya, M.7
Asada, H.8
Gojo, S.9
Imanishi, J.10
Matsubara, H.11
Yoshikawa, T.12
-
133
-
-
0020321716
-
Introduction of macromolecules into cultured mammalian cells by osmotic lysis of pinocytic vesicles
-
Okada, C. Y.; Rechsteiner, M. Introduction of macromolecules into cultured mammalian cells by osmotic lysis of pinocytic vesicles. Cell, 1982, 29, 33-41.
-
(1982)
Cell
, vol.29
, pp. 33-41
-
-
Okada, C.Y.1
Rechsteiner, M.2
-
134
-
-
3142618387
-
RNA interference by osmotic lysis of pinosomes: Liposome-independent transfection of siRNAs into mammalian cells
-
Gruber, J.; Boese, G.; Tuschl, T.; Osborn, M.; Weber, K. RNA interference by osmotic lysis of pinosomes: liposome-independent transfection of siRNAs into mammalian cells. Biotechniques, 2004, 37, 96-102.
-
(2004)
Biotechniques
, vol.37
, pp. 96-102
-
-
Gruber, J.1
Boese, G.2
Tuschl, T.3
Osborn, M.4
Weber, K.5
-
135
-
-
59249102884
-
Transfer of small interfering RNA by single-cell electroporation in cerebellar cell cultures
-
Tanaka, M.; Yanagawa, Y.; Hirashima, N. Transfer of small interfering RNA by single-cell electroporation in cerebellar cell cultures. J. Neurosci. Methods, 2009, 178, 80-86.
-
(2009)
J. Neurosci. Methods
, vol.178
, pp. 80-86
-
-
Tanaka, M.1
Yanagawa, Y.2
Hirashima, N.3
-
136
-
-
34250726267
-
Electric fields in tumors exposed to external voltage sources: Implication for electric field-mediated drug and gene delivery
-
Mossop, B. J.; Barr, R. C.; Henshaw, J. W.; Zaharoff, D. A.; Yuan, F. Electric fields in tumors exposed to external voltage sources: implication for electric field-mediated drug and gene delivery. Ann. Biomed. Eng., 2006, 34, 1564-1572.
-
(2006)
Ann. Biomed. Eng.
, vol.34
, pp. 1564-1572
-
-
Mossop, B.J.1
Barr, R.C.2
Henshaw, J.W.3
Zaharoff, D.A.4
Yuan, F.5
-
137
-
-
33751208913
-
Suppression of tumor growth by intratumoral injection of short hairpin RNA-expressing plasmid DNA targeting beta-catenin or hypoxia-inducible factor 1alpha
-
Takahashi, Y.; Nishikawa, M.; Takakura, Y. Suppression of tumor growth by intratumoral injection of short hairpin RNA-expressing plasmid DNA targeting beta-catenin or hypoxia-inducible factor 1alpha. J. Control Release, 2006, 116, 90-95.
-
(2006)
J. Control Release
, vol.116
, pp. 90-95
-
-
Takahashi, Y.1
Nishikawa, M.2
Takakura, Y.3
-
138
-
-
67749084133
-
RNA interference for nog gin enhances the biological activity of bone morphogenetic proteins in vivo and in vitro
-
Takayama, K.; Suzuki, A.; Manaka, T.; Taguchi, S.; Hashimoto, Y.; Imai, Y.; Wakitani, S.; Takaoka, K. RNA interference for nog gin enhances the biological activity of bone morphogenetic proteins in vivo and in vitro. J. Bone Miner. Metab., 2009, 27, 402-411.
-
(2009)
J. Bone Miner. Metab.
, vol.27
, pp. 402-411
-
-
Takayama, K.1
Suzuki, A.2
Manaka, T.3
Taguchi, S.4
Hashimoto, Y.5
Imai, Y.6
Wakitani, S.7
Takaoka, K.8
-
139
-
-
48249131634
-
Gene silencing by RNAi in mouse Sertoli cells
-
Gonzalez-Gonzalez, E.; Lopez-Casas, P. P.; Del Mazo, J. Gene silencing by RNAi in mouse Sertoli cells. Reprod. Biol. Endocrinol., 2008, 6, 29.
-
(2008)
Reprod. Biol. Endocrinol.
, vol.6
, pp. 29
-
-
Gonzalez-Gonzalez, E.1
Lopez-Casas, P.P.2
Del Mazo, J.3
-
140
-
-
1642538990
-
Vector-based in vivo RNA interference: Dose-and time-dependent suppression of transgene expression
-
Kobayashi, N.; Matsui, Y.; Kawase, A.; Hirata, K.; Miyagishi, M.; Taira, K.; Nishikawa, M.; Takakura, Y. Vector-based in vivo RNA interference: dose-and time-dependent suppression of transgene expression. J. Pharmacol. Exp. Ther., 2004, 308, 688-693.
-
(2004)
J. Pharmacol. Exp. Ther.
, vol.308
, pp. 688-693
-
-
Kobayashi, N.1
Matsui, Y.2
Kawase, A.3
Hirata, K.4
Miyagishi, M.5
Taira, K.6
Nishikawa, M.7
Takakura, Y.8
-
141
-
-
36849037941
-
Potency of siRNA versus shRNA mediated knockdown in vivo
-
McAnuff, M. A.; Rettig, G. R.; Rice, K. G. Potency of siRNA versus shRNA mediated knockdown in vivo. J. Pharm. Sci., 2007, 96, 2922-30.
-
(2007)
J. Pharm. Sci.
, vol.96
, pp. 2922-2930
-
-
McAnuff, M.A.1
Rettig, G.R.2
Rice, K.G.3
-
142
-
-
0032805251
-
Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA
-
Liu, F.; Song, Y.; Liu, D. Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA. Gene. Ther., 1999, 6, 1258-1266.
-
(1999)
Gene. Ther.
, vol.6
, pp. 1258-1266
-
-
Liu, F.1
Song, Y.2
Liu, D.3
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