Efficacy and safety of add on low-dose mirtazapine in depression

Indian Journal of Pharmacology

Volumn 44, Issue 2, 2012, Pages 173-177

  Matreja, Prithpal S ^a   Badyal, Dinesh K ^b   Deswal, Randhir S ^b   Sharma, Arvind ^b  

^a GIAN SAGAR MEDICAL COLLEGE AND HOSPITAL   (India)

^b CHRISTIAN MEDICAL COLLEGE   (India)

Author keywords

Add on; depression; mirtazapine; selective serotonin reuptake inhibitor

Indexed keywords

CITALOPRAM; ESCITALOPRAM; FLUOXETINE; MIRTAZAPINE; PAROXETINE; SERTRALINE;

ADD ON THERAPY; ADULT; ARTICLE; CONTROLLED STUDY; DEPRESSION; DRUG EFFECT; DRUG EFFICACY; DRUG RESPONSE; DRUG SAFETY; EJACULATION DISORDER; FEMALE; HUMAN; INDIA; INSOMNIA; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; NAUSEA; OPEN STUDY; RANDOMIZED CONTROLLED TRIAL; REMISSION; SEXUAL DYSFUNCTION; SOMNOLENCE; TREATMENT OUTCOME;

EID: 84858952356     PISSN: 02537613     EISSN: 19983751     Source Type: Journal    
DOI: 10.4103/0253-7613.93843     Document Type: Article

References (21)

1. nd ed. New York: Oxford University Press for the World Bank; 2006. p. 605-25.
2. World Health Organization. Mental and behavioural disorders, department of mental health [Online]. 2000. Available from: http://www.who.int/mental- health/media/en/59.pdf. [Last cited in 2011].
3. Aaron R, Joseph A, Abraham S, Muliyil J, George K, Prasad J, et al. Suicides in young people in rural southern India. Lancet 2004;363:1117-8.
4. th ed. New York: McGraw-Hill; 2006. p. 429-60.
5. Davidson JR, Meltzer-Brody SE. The under recognition and under treatment of depression: What is the breadth and depth of the problem? J Clin Psychiatry 1999;60:4-9.
6. Whooley MA, Simon GE. Managing depression in medical outpatients. N Engl J Med 2000;343:1942-50.
7. Carpenter LL, Jocic Z, Hall JM, Rasmussen SA, Price LH. Mirtazapine augmentation in the treatment of refractory depression. J Clin Psychiatry 1999;60:45-9.
8. Papakostas GI, Homberger CH, Fava M. A meta-analysis of clinical trials comparing mirtazapine with selective serotonin reuptake inhibitors for the treatment of major depressive disorder. J Psychopharmacol 2008;22:843-8.
9. th ed., Vol. 1. Philadelphia: Lippincott Williams and Wilkins; 2009. p. 1139-51.
10. th ed. Text Revision (DSM-IV-TR). Washington D.C.: American Psychiatric Association; 2000. p. 356.
11. Hamilton M. A rating scale for depression. J Neurol Neurosurg Psychiatry 1960;23:56-62.
12. Montgomery SA, Asberg MA. A new depression scale designed to be sensitive to change. Br J Psychiatry 1979;134:382-9.
13. Singh G. A new depressive inventory (Amritsar Depressive Inventory). Indian J Psychiatry 1974;16:183-8.
14. Thase ME. Methodology to measure onset of action. J Clin Psychiatry 2001;62 Suppl 15:18-21.
15. Nierenberg AA. Do some antidepressants work faster than others? J Clin Psychiatry 2001;62 Suppl 15:22-5.
16. Mulrow CD, William JW, Chiquette E, Aguilar C, Hitchcock-Noel P, Lee S, et al. Efficacy of newer medication for treating depression in primary care patients. Am J Med 2000;108:54-64.
17. Haddjeri N, Blier P, de Montigny C. Noradrenergic modulation of central serotonergic neurotransmission: Acute and long-term actions of mirtazapine. Int Clin Psychopharmacol 1995;10 Suppl 4:11-7.
18. Ruigt GS, Kemp B, Groenhout CM, Kamphuisen HA. Effect of the antidepressant Org 3770 on human sleep. Eur J Clin Pharmacol 1990;38:551-4.
19. Sorensen M, Jorgensen J, Viby-Mogensen J, Bettum V, Dunbar GC, Steffensen K. A double-blind group comparative study using the new anti-depressant Org 3770, placebo and diazepam in patients with expected insomnia and anxiety before elective gynaecological surgery. Acta Psychiatr Scand 1985;71:339-46.
20. Carpenter LL, Yasmina S, Pricea LH. A double-blind, placebo-controlled study of antidepressant augementation with mirtazapine. Biol Psychiatry 2001;51:183-8.
21. Pallanti S, Quercioli L, Bruscoli M. Response acceleration with mirtazapine augmentation of citalopram in obsessive-compulsive disorder patients without comorbid depression: A Pilot Study. J Clin Psychiatry 2004;65:1394-9.