Influence of antibiotic susceptibility patterns on empiric antibiotic prescribing for children hospitalized with community-acquired pneumonia

Pediatric Infectious Disease Journal

Volumn 31, Issue 4, 2012, Pages 331-336

  Ambroggio, Lilliam ^a   Tabb, Loni Philip ^a   O'Meara, Timothy ^b   Sheffler Collins, Seth ^b   McGowan, Karin L ^b   Shah, Samir S ^c,d  

^a DREXEL UNIVERSITY   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^d UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

bacterial drug resistance; child; pediatric hospitals; Streptococcus pneumoniae

Indexed keywords

AMINOPENICILLIN; ANTIBIOTIC AGENT; CEPHALOSPORIN; CLINDAMYCIN; MACROLIDE; PENICILLIN G; VANCOMYCIN;

ADOLESCENT; ADULT; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ANTIBIOTIC THERAPY; ARTICLE; BACTERIUM ISOLATE; CHILD; COMMUNITY ACQUIRED PNEUMONIA; CONTROLLED STUDY; HOSPITAL DISCHARGE; HOSPITALIZATION; HUMAN; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MEDICAL PRACTICE; MULTICENTER STUDY; PRESCHOOL CHILD; PRESCRIPTION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SCHOOL CHILD; TREATMENT OUTCOME;

ADOLESCENT; ANTI-BACTERIAL AGENTS; CHILD; CHILD, PRESCHOOL; COMMUNITY-ACQUIRED INFECTIONS; CROSS-SECTIONAL STUDIES; DRUG PRESCRIPTIONS; DRUG THERAPY; FEMALE; HOSPITALS, PEDIATRIC; HUMANS; INFANT; MALE; MICROBIAL SENSITIVITY TESTS; PENICILLIN RESISTANCE; PNEUMONIA, PNEUMOCOCCAL; STREPTOCOCCUS PNEUMONIAE; UNITED STATES;

EID: 84858795502     PISSN: 08913668     EISSN: 15320987     Source Type: Journal    
DOI: 10.1097/INF.0b013e3182489cc4     Document Type: Article

References (31)

1. Nugent R, Back E, Beith A. The Race Against Drug Resistance. Washington, DC: Center for Global Development; 2010.
2. Peters NK, Dixon DM, Holland SM, et al. The research agenda of the National Institute of Allergy and Infectious Diseases for antimicrobial resistance. J Infect Dis. 2008;197:1087-1093. (Pubitemid 351590043)
3. The Infectious Diseases Society of America. Bad Bugs, No Drugs. Alexandria, VA: The Infectious Diseases Society of America; 2004.
4. Davey P, Brown E, Fenelon L, et al. Interventions to improve antibiotic prescribing practices for hospital inpatients (Review). The Cochrane Library 2009.
5. Lacy MK, Klutman NE, Horvat RT, et al. Antibiograms: new NCCLS guidelines, development, and clinical application. Hosp Pharm. 2004;39:542-553. (Pubitemid 38738026)
6. Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Susceptibility Testing; Twenty-First Informational Supplement. Wayne, PA: Clinical and Laboratory Standards Institute; 2011.
7. Centers for Disease Control and Prevention. Effects of new penicillin susceptibility breakpoints for Streptococcus pneumoniae-United States, 2006-2007. MMWR Morb Mortal Wkly Rep. 2008;57:1353-1355.
8. Mongelluzzo J, Mohamad Z, Ten Have TR, et al. Corticosteroids and mortality in children with bacterial meningitis. JAMA. 2008;299:2048-2055. (Pubitemid 351656586)
9. Shah SS, Hall M, Srivastava R, et al. Intravenous immunoglobulin in children with streptococcal toxic shock syndrome. Clin Infect Dis. 2009;49:1369-1376.
10. Feigin R, Cherry J, Demmler-Harrison G, et al, eds. Feigin and Cherry's Textbook of Pediatric Infectious Diseases. 6th ed. Philadelphia, PA: Saunders Elsevier; 2009.
11. Feudtner C, Hays RM, Haynes G, et al. Deaths attributed to pediatric complex chronic conditions: national trends and implications for supportive care services. Pediatrics. 2001;107:E99.
12. Zeger SL, Liang KY. Longitudinal data analysis for discrete and continuous outcomes. Biometrics. 1986;42:121-130.
13. Hubbard AE, Ahern J, Fleischer NL, et al. To GEE or not to GEE: comparing population average and mixed models for estimating the associations between neighborhood risk factors and health. Epidemiology. 2010;21:467-474.
14. Subramanian SV, O'Malley AJ. Modeling neighborhood effects: the futility of comparing mixed and marginal approaches. Epidemiology. 2010;21:475-8; discussion 479.
15. Raudenbush SW, Bryk AS. Hierarchical Linear Models: Applications and Data Analysis Methods. 2nd ed. Thousand Oaks, CA: Sage; 2002.
16. Maldonado G, Greenland S. Simulation study of confounder-selection strategies. Am J Epidemiol. 1993;138:923-936. (Pubitemid 24002359)
17. Verbeke G, Molenberghs G. Linear Mixed Models for Longitudinal Data. New York, NY: Springer; 2000.
18. Long SS, Pickering LK, Prober CG, eds. Principles and Practice of Pediatric Infectious Diseases. 3rd ed. New York, NY: Churchill Livingstone; 2008.
19. Merlo J, Chaix B, Ohlsson H, et al. A brief conceptual tutorial of multilevel analysis in social epidemiology: using measures of clustering in multilevel logistic regression to investigate contextual phenomena. J Epidemiol Community Health. 2006;60:290-297.
20. Larsen K, Petersen JH, Budtz-Jørgensen E, et al. Interpreting parameters in the logistic regression model with random effects. Biometrics. 2000;56:909-914.
21. Gerber JS, Newland JG, Coffin SE, et al. Variability in antibiotic use at children's hospitals. Pediatrics. 2010;126:1067-1073.
22. Bradley JS, Byington CL, Shah SS, et al. The management of community-acquired pneumonia in infants and children older than 3 months of age: clinical practice guidelines by the Pediatric Infectious Diseases Society and the Infectious Diseases Society of America. Clin Infect Dis. 2011;53:e25-e76.
23. Yu VL, Chiou CC, Feldman C, et al.; International Pneumococcal Study Group. An international prospective study of pneumococcal bacteremia: correlation with in vitro resistance, antibiotics administered, and clinical outcome. Clin Infect Dis. 2003;37:230-237. (Pubitemid 36930354)
24. Cardoso MR, Nascimento-Carvalho CM, Ferrero F, et al.; CARIBE Group. Penicillin-resistant pneumococcus and risk of treatment failure in pneumonia. Arch Dis Child. 2008;93:221-225. (Pubitemid 352025494)
25. Weinstein MP, Klugman KP, Jones RN. Rationale for revised penicillin susceptibility breakpoints versus Streptococcus pneumoniae: coping with antimicrobial susceptibility in an era of resistance. Clin Infect Dis. 2009;48:1596-1600.
26. Saha SK, Darmstadt GL, Baqui AH, et al. Rapid identification and antibiotic susceptibility testing of Salmonella enterica serovar Typhi isolated from blood: implications for therapy. J Clin Microbiol. 2001;39:3583-3585. (Pubitemid 32954505)
27. Jorgensen JH. Who defines resistance? The clinical and economic impact of antimicrobial susceptibility testing breakpoints. Semin Pediatr Infect Dis. 2004;15:105-108. (Pubitemid 38881337)
28. Khawcharoenporn T, Vasoo S, Ward E, et al. High rates of quinolone resistance among urinary tract infections in the ED. Am J Emerg Med. 2012;30:68-74.
29. Hulscher ME, Grol RP, van der Meer JW. Antibiotic prescribing in hospitals: a social and behavioural scientific approach. Lancet Infect Dis. 2010;10:167-175.
30. Guevara RE, Butler JC, Marston BJ, et al. Accuracy of ICD-9-CM codes in detecting community-acquired pneumococcal pneumonia for incidence and vaccine efficacy studies. Am J Epidemiol. 1999;149:282-289. (Pubitemid 29053170)
31. Whittle J, Fine MJ, Joyce DZ, et al. Community-acquired pneumonia: can it be defined with claims data? Am J Med Qual. 1997;12:187-193. (Pubitemid 127447173)