Label-free monitoring of colonic cancer progression using multiphoton microscopy

Biomedical Optics Express

Volumn 2, Issue 3, 2011, Pages 615-619

  Zhuo, Shuangmu ^a   Yan, Jun ^b   Chen, Gang ^b   Chen, Jianxin ^a   Liu, Yuchun ^a   Lu, Jianping ^b   Zhu, Xiaoqin ^a   Jiang, Xingshan ^a   Xie, Shusen ^a  

^a FUJIAN NORMAL UNIVERSITY   (China)

^b FUJIAN PROVINCIAL TUMOR HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

DIAGNOSIS; TISSUE;

COLONIC CANCERS; CONVENTIONAL METHODS; EARLY DIAGNOSIS; IN-SITU; LABEL FREE; LABEL-FREE MONITORING; MALIGNANT LESION; MULTI-PHOTON MICROSCOPY; MULTIPHOTON IMAGING; REDOX RATIO; SUB-CELLULAR;

DISEASES;

EID: 84858794545     PISSN: None     EISSN: 21567085     Source Type: Journal    
DOI: 10.1364/BOE.2.000615     Document Type: Article

References (21)

1. A. Jemal, R. Siegel, E. Ward, Y. Hao, J. Xu, and M. J. Thun, "Cancer statistics, 2009," CA Cancer J. Clin. 59(4), 225-249 (2009).
2. M. Goetz and R. Kiesslich, "Advances of endomicroscopy for gastrointestinal physiology and diseases," Am. J. Physiol. Gastrointest. Liver Physiol. 298(6), G797-G806 (2010).
3. R. Kiesslich, J. Burg, M. Vieth, J. Gnaendiger, M. Enders, P. Delaney, A. Polglase, W. McLaren, D. Janell, S. Thomas, B. Nafe, P. R. Galle, and M. F. Neurath, "Confocal laser endoscopy for diagnosing intraepithelial neoplasias and colorectal cancer in vivo," Gastroenterology 127(3), 706-713 (2004).
4. W. R. Zipfel, R. M. Williams, R. Christie, A. Y. Nikitin, B. T. Hyman, and W. W. Webb, "Live tissue intrinsic emission microscopy using multiphoton-excited native fluorescence and second harmonic generation," Proc. Natl. Acad. Sci. U.S.A. 100(12), 7075-7080 (2003).
5. M. C. Skala, K. M. Riching, A. Gendron-Fitzpatrick, J. Eickhoff, K. W. Eliceiri, J. G. White, and N. Ramanujam, "In vivo multiphoton microscopy of NADH and FAD redox states, fluorescence lifetimes, and cellular morphology in precancerous epithelia," Proc. Natl. Acad. Sci. U.S.A. 104(49), 19494-19499 (2007).
6. P. T. C. So, C. Y. Dong, B. R. Masters, and K. M. Berland, "Two-photon excitation fluorescence microscopy," Annu. Rev. Biomed. Eng. 2(1), 399-429 (2000).
7. S. M. Zhuo, L. Q. Zheng, J. X. Chen, S. S. Xie, X. Q. Zhu, and X. S. Jiang, "Depth-cumulated epithelial redox ratio and stromal collagen quantity as quantitative intrinsic indicators for differentiating normal, inflammatory, and dysplastic epithelial tissues," Appl. Phys. Lett. 97(17), 173701 (2010).
8. P. J. Campagnola and L. M. Loew, "Second-harmonic imaging microscopy for visualizing biomolecular arrays in cells, tissues and organisms," Nat. Biotechnol. 21(11), 1356-1360 (2003).
9. V. A. Hovhannisyan, P.-J. Su, S.-J. Lin, and C. Y. Dong, "Quantifying thermodynamics of collagen thermal denaturation by second harmonic generation imaging," Appl. Phys. Lett. 94(23), 233902 (2009).
10. S. M. Zhuo, J. X. Chen, G. Z. Wu, S. S. Xie, L. Q. Zheng, X. S. Jiang, and X. Q. Zhu, "Quantitatively linking collagen alteration and epithelial tumor progression by second harmonic generation microscopy," Appl. Phys. Lett. 96(21), 213704 (2010).
11. R. Cicchi, A. Crisci, A. Cosci, G. Nesi, D. Kapsokalyvas, S. Giancane, M. Carini, and F. S. Pavone, "Time- and Spectral-resolved two-photon imaging of healthy bladder mucosa and carcinoma in situ," Opt. Express 18(4), 3840-3849 (2010).
12. K. König, A. Ehlers, I. Riemann, S. Schenkl, R. Bückle, and M. Kaatz, "Clinical two-photon microendoscopy," Microsc. Res. Tech. 70(5), 398-402 (2007).
13. M. Gu, H. C. Bao, and J. L. Li, "Cancer-cell microsurgery using nonlinear optical endomicroscopy," J. Biomed. Opt. 15(5), 050502 (2010).
14. J. R. Jass, V. L. Whitehall, J. Young, and B. A. Leggett, "Emerging concepts in colorectal neoplasia," Gastroenterology 123(3), 862-876 (2002).
15. A. Leslie, F. A. Carey, N. R. Pratt, and R. J. Steele, "The colorectal adenoma-carcinoma sequence," Br. J. Surg. 89(7), 845-860 (2002).
16. S. Zhuo, J. Chen, T. Luo, D. Zou, and J. Zhao, "Multimode nonlinear optical imaging of the dermis in ex vivo human skin based on the combination of multichannel mode and Lambda mode," Opt. Express 14(17), 7810-7820 (2006).
17. S. M. Zhuo, J. X. Chen, S. S. Xie, Z. B. Hong, and X. S. Jiang, "Extracting diagnostic stromal organization features based on intrinsic two-photon excited fluorescence and second-harmonic generation signals," J. Biomed. Opt. 14(2), 020503 (2009).
18. S. Huang, A. A. Heikal, and W. W. Webb, "Two-photon fluorescence spectroscopy and microscopy of NAD(P)H and flavoprotein," Biophys. J. 82(5), 2811-2825 (2002).
19. C. Y. Dong, P. T. C. So, C. Buehler, and E. Gratton, "Spatial resolution in pump-probe microscopy," Optik (Stuttg.) 106, 7-14 (1997).
20. J. N. Rogart, J. Nagata, C. S. Loeser, R. D. Roorda, H. Aslanian, M. E. Robert, W. R. Zipfel, and M. H. Nathanson, "Multiphoton imaging can be used for microscopic examination of intact human gastrointestinal mucosa ex vivo," Clin. Gastroenterol. Hepatol. 6(1), 95-101 (2008).
21. M. C. Skala, J. M. Squirrell, K. M. Vrotsos, J. C. Eickhoff, A. Gendron-Fitzpatrick, K. W. Eliceiri, and N. Ramanujam, "Multiphoton microscopy of endogenous fluorescence differentiates normal, precancerous, and cancerous squamous epithelial tissues," Cancer Res. 65(4), 1180-1186 (2005).