Determination and validation of tetrodotoxin in human whole blood using hydrophilic interaction liquid chromatography-tandem mass spectroscopy and its application

Forensic Science International

Volumn 217, Issue 1-3, 2012, Pages 76-80

  Cho, Hwang Eui ^b   Ahn, Su Youn ^a,b   Son, In Seop ^b   In, Sangwhan ^a   Hong, Ran Seon ^b   Kim, Dong Woo ^a   Woo, Sang Hee ^a   Moon, Dong Cheul ^b   Kim, Suncheun ^a  

^a National Forensic Service   (South Korea)

^b Chungbuk National University   (South Korea)

Author keywords

Intoxication; PC HILIC; Tetrodotoxin (TTX); Voglibose, Postmortem

Indexed keywords

ACETIC ACID; ACETONITRILE; AMPHOLYTE; TETRODOTOXIN; VOGLIBOSE;

ACCURACY; ADULT; ARTICLE; BLOOD ANALYSIS; BLOOD SAMPLING; CASE REPORT; CONTROLLED STUDY; ELECTROSPRAY MASS SPECTROMETRY; ELUTION; FISHERMAN; FOOD POISONING; HUMAN; HYDROPHILIC INTERACTION CHROMATOGRAPHY; LIMIT OF DETECTION; LIMIT OF QUANTITATION; MALE; MONITORING; MULTIPLE REACTION MONITORING; PHOSPHORYLCHOLINE HYDROPHILIC INTERACTION LIQUID CHROMATOGRAPHY; PRECIPITATION; PRIORITY JOURNAL; PROTEIN PRECIPITATION; QUANTITATIVE ANALYSIS; REPRODUCIBILITY; RETENTION TIME; SERUM; SOLID PHASE EXTRACTION; SURVIVOR; TANDEM MASS SPECTROMETRY; TIME; TOXIN ANALYSIS; VICTIM;

EID: 84858793280     PISSN: 03790738     EISSN: 18726283     Source Type: Journal    
DOI: 10.1016/j.forsciint.2011.10.026     Document Type: Article

References (20)

1. Ahasan A.M.N., Mamun A.A., Karim S.R., Bakar M.A., Gazi E.A., Bala C.S. Paralytic complications of puffer fish (tetrodotoxin) poisoning. Singapore Med. J. 2004, 45:73-74.
2. Narahashi T. Tetrodotoxin. Proc. Jpn. Acad. Ser. B 2008, 84:147-154.
3. Chew S.K., Goh C.H., Wang K.W., Mah P.K., Tan B.Y. Puffer fish (tetrodotoxin) poisoning: clinical report and role of anti-cholinesterase drugs in therapy. Singapore Med. J. 1983, 24:168-171.
4. Tetradotoxin poisoning associated with eating puffer fish transported from Japan-California, 1996. Morb. Mortal. Wkly. Rep. 1996, 45:389-391.
5. Chowdhury F.R., Nazmul Ahasan H.A.M., Mamunur Rashid A.K.M., Al Mamun A., Khaliduzzaman S.M. Tetrodotoxin poisoning: a clinical analysis role of neostigmine and short-term outcome of 53 cases. Singapore Med. J. 2007, 48:830-833.
6. How C.K., Chern C.H., Huang Y.C., Wang L.M., Lee C.H. Tetrodotoxin Poisoning. Am. J. Emerg. Med. 2003, 21:51-54.
7. Yasumoto T., Michishita T. Fluorometric determination of tetrodotoxin by high performance liquid chromatography. Agric. Biol. Chem. 1985, 49:3077-3080.
8. Kono M., Matsui T., Furukawa K., Takase T., Yamamori K., Kaneda H., Aoki D., Jang J.H., Yotsu-Yamashita M. Examination of transformation among tetrodotoxin and its analogs in the living cultured juvenile puffer fish, kusafugu Fugu niphobles by intramuscular administration. Toxicon 2008, 52:714-720.
9. Tsai Y.H., Hwang D.F., Cheng C.A., Hwang C.C., Deng J.F. Determination of tetrodotoxin in human urine and blood using C18 cartridge column, ultrafiltration and LC-MS. J. Chromatogr. B 2006, 832:75-80.
10. Kurono S., Hattori H., Suzuki O., Yamada T., Seno H. Sensitive analysis of tetrodotoxin in human plasma by solid-phase extractions and gas chromatography/mass spectrometry. Anal. Lett. 2001, 34:2439-2446.
11. Noguchi T., Narita H., Maruyama J., Hashimoto K. Tetrodotoxin in the starfishes Astropecten polyacanthus, in association with toxification of a trumpet shell Boshubora Charonia sauliae. Bull. Japan. Soc. Sci. Fish. 1982, 48:1173-1177.
12. Kawatsu K., Shibata T., Hamano Y. Application of immunoaffinity chromatography for detection of tetrodotoxin from urine samples of poisoned patients. Toxicon 1999, 37:325-333.
13. Horie M., Kobayashi S., Shimizu N., Nakazawa H. Determination of tetrodotoxin in puffer-fish by liquid chromatography-electrospray ionization mass spectrometry. Analyst 2002, 127:755-759.
14. Nakagawa T., Jang J., Yotsu-Yamashita M. Hydrophilic interaction liquid chromatography-electrospray ionization mass spectrometry of tetrodotoxin and its analogs. Anal. Biochem. 2006, 352:142-144.
15. Jen H.C., Lin S.J., Tsai Y.H., Chen C.H., Lin Z.C., Hwang D.F. Tetrodotoxin poisoning evidenced by solid-phase extraction combining with liquid chromatography-tandem mass spectrometry. J. Chromatogr. B 2008, 871:95-100.
16. O'Leary M.A., Schneider J.J., Isbister G.K. Use of high performance liquid chromatography to measure tetrodotoxin in serum and urine of poisoned patients. Toxicon 2004, 44:549-553.
17. Huangb H.-N., Lin J., Lin H.-L. Identification and quantification of tetrodotoxin in the marine gastropod Nassarius by LC-MS. Toxicon 2008, 51:774-779.
18. Shoji Y., Yotsu-Yamashita M., Miyazawa T., Yasumoto T. Electrospray ionization mass spectrometry of tetrodotoxin and its analogs: liquid chromatography/mass spectrometry tandem mass spectrometry, and liquid chromatography/tandem mass spectrometry. Anal. Biochem. 2001, 290:10-17.
19. Pires O.R., Sebben A., Schwartz E.F., Morales R.A., Bloch C., Schwartz C.A. Further report of the occurrence of tetrodotoxin and new analogues in the Anuran family Brachycephalidae. Toxicon 2005, 45:73-79.
20. Wang X., Li W., Rasmussen H.T. Orthogonal method development using hydrophilic interaction chromatography and reversed-phase high-performance liquid chromatography for the determination of pharmaceuticals and impurities. J. Chromatogr. A 2005, 1083:58-62.