Optimized dextran-polyethylenimine conjugates are efficient non-viral vectors with reduced cytotoxicity when used in serum containing environments

International Journal of Pharmaceutics

Volumn 427, Issue 1, 2012, Pages 71-79

  Jiang, Dahai ^a   Salem, Aliasger K ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

Cationic polymer; Complexes; Dextran; Gene delivery; Nanoparticles; Nanoplexes; Non viral; pDNA; PEI; Plasmid DNA; Polyethylenimine; Serum; Transfection

Indexed keywords

DEXTRAN; DRUG CARRIER; FIREFLY LUCIFERASE; PLASMID DNA; POLYETHYLENEIMINE; POLYSACCHARIDE;

ANIMAL CELL; ARTICLE; CELL STRAIN HEK293; CONJUGATE; CONTROLLED STUDY; CYTOTOXICITY; DRUG STABILITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INCUBATION TIME; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; SERUM; TURBIDITY;

ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; DEXTRANS; DRUG CARRIERS; GENES, REPORTER; HEK293 CELLS; HUMANS; LUCIFERASES, FIREFLY; MICROSCOPY, CONFOCAL; PLASMIDS; POLYETHYLENEIMINE; SERUM; TRANSFECTION;

EID: 84858745745     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.10.032     Document Type: Article

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