ARIEL and AMELIA: Testing for an accumulation of rare variants using next-generation sequencing data

Human Heredity

Volumn 73, Issue 2, 2012, Pages 84-94

  Asimit, Jennifer L ^a   Day Williams, Aaron G ^a   Morris, Andrew P ^b   Zeggini, Eleftheria ^a  

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Accounting for uncertainty; Association analysis; Complex trait; Exome sequencing; Whole genome sequencing

Indexed keywords

ACCUMULATION OF RARE VARIANTS INTEGRATED AND EXTENDEND LOCUS SPECIFIC TEST; ALLELE; ALLELE MATCHING EMPIRICAL LOCUS SPECIFIC INTEGRATED ASSOCIATION TEST; ARTICLE; COMPUTER PROGRAM; GENE LOCUS; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SCREENING; GENETIC VARIABILITY; REGRESSION ANALYSIS;

ALLELES; COMPUTER SIMULATION; GENETIC ASSOCIATION STUDIES; GENETIC VARIATION; GENOTYPE; HUMANS; LOGISTIC MODELS; SOFTWARE;

EID: 84858729755     PISSN: 00015652     EISSN: 14230062     Source Type: Journal    
DOI: 10.1159/000336982     Document Type: Article

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