Science to practice: What do molecular biologic studies in rodent models add to our understanding of interventional oncologic procedures including percutaneous ablation by using glyceraldehyde-3-phosphate dehydrogenase antagonists?

Radiology

Volumn 262, Issue 3, 2012, Pages 737-739

  Goldberg, S Nahum ^a,b  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BROMOPYRUVIC ACID; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; OXIDOREDUCTASE INHIBITOR; UNCLASSIFIED DRUG;

APOPTOSIS; DISEASE MODEL; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; LIVER CELL CARCINOMA; MOLECULARLY TARGETED THERAPY; NONHUMAN; ONCOGENE C JUN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA INTERFERENCE; SHORT SURVEY; TUMOR ABLATION;

ANIMALS; CARCINOMA, HEPATOCELLULAR; DISEASE MODELS, ANIMAL; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; HUMANS; LIVER NEOPLASMS; PYRUVATES; RNA, SMALL INTERFERING;

EID: 84858726317     PISSN: 00338419     EISSN: 15271315     Source Type: Journal    
DOI: 10.1148/radiol.11112716     Document Type: Short Survey

References (10)

1. Ganapathy-Kanniappan S, Kunjithapatham R, Torbenson MS, et al. Human hepatocellular carcinoma in a mouse model: assessment of tumor response to percutaneous ablation by using glyceraldehyde-3-phosphate dehydrogenase antagonists. Radiology2012; 262(3)834-845.
2. Feitelson MA, Pan J, Lian Z. Early molecular and genetic determinants of primary liver malignancy. Surg Clin North Am 2004;84(2):339-354. (Pubitemid 38388271)
3. Lewandowski RJ, Geschwind JF, Liapi E, Salem R. Transcatheter intraarterial therapies: rationale and overview. Radiology 2011;259(3):641-657.
4. Ahmed M, Brace CL, Lee FT Jr, Goldberg SN. Principles of and advances in percutaneous ablation. Radiology 2011;258(2):351-369.
5. Ganapathy-Kanniappan S, Vali M, Kunjithapatham R, et al. 3-bromopyruvate: a new targeted antiglycolytic agent and a promise for cancer therapy. Curr Pharm Biotechnol 2010;11(5):510-517.
6. Prat A, Ellis MJ, Perou CM. Practical implications of gene-expression-based assays for breast oncologists. Nat Rev Clin Oncol 2011 9(1):48-57.
7. Carthew RW, Sontheimer EJ. Origins and mechanisms of miRNAs and siRNAs. Cell 2009;136(4):642-655.
8. Hale AJ, Smith CA, Sutherland LC, et al. Apoptosis: molecular regulation of cell death. Eur J Biochem 1996;237(3):884.
9. Goldberg SN, Bonn J, Dodd G, et al. Society of Interventional Radiology Interventional Oncology Task Force: interventional oncology research vision statement and critical assessment of the state of research affairs. J Vasc Interv Radiol 2005;16(10):1287-1294. (Pubitemid 41463985)
10. Sawyer GJ, Rela M, Davenport M, Whitehorne M, Zhang X, Fabre JW. Hydrodynamic gene delivery to the liver: theoretical and practical issues for clinical application. Curr Gene Ther 2009;9(2):128-135.