메뉴 건너뛰기




Volumn 11, Issue 11, 2011, Pages 1631-1640

Targeted therapies used sequentially in metastatic renal cell cancer: Overall results from a large experience

Author keywords

mTOR inhibitors; Renal cell carcinoma; Sorafenib; Sunitinib; Targeted therapies

Indexed keywords

AXITINIB; BEVACIZUMAB; EVEROLIMUS; SORAFENIB; SUNITINIB; TEMSIROLIMUS; ANTINEOPLASTIC AGENT;

EID: 84858710583     PISSN: 14737140     EISSN: 17448328     Source Type: Journal    
DOI: 10.1586/era.11.154     Document Type: Article
Times cited : (21)

References (38)
  • 1
    • 3142778420 scopus 로고    scopus 로고
    • Epidemiology of renal cell carcinoma
    • Lindblad P. Epidemiology of renal cell carcinoma. Scand. J. Surg. 93(2), 88-96 (2004).
    • (2004) Scand. J. Surg , vol.93 , Issue.2 , pp. 88-96
    • Lindblad, P.1
  • 2
    • 0033526386 scopus 로고    scopus 로고
    • Rising incidence of renal cell cancer in the United States
    • Chow WH, Devesa SS, Warren JL, Fraumeni JF Jr. Rising incidence of renal cell cancer in the United States. JAMA 281(17), 1628-1631 (1999).
    • (1999) JAMA , vol.281 , Issue.17 , pp. 1628-1631
    • Chow, W.H.1    Devesa, S.S.2    Warren, J.L.3    Fraumeni, J.F.4
  • 3
    • 0034003853 scopus 로고    scopus 로고
    • Increase in incidental renal cell carcinoma in the northern part of The Netherlands
    • Bos SD, Mellema CT, Mensink HJ. Increase in incidental renal cell carcinoma in the northern part of The Netherlands. Eur. Urol. 37(3), 267-270 (2000).
    • (2000) Eur. Urol , vol.37 , Issue.3 , pp. 267-270
    • Bos, S.D.1    Mellema, C.T.2    Mensink, H.J.3
  • 4
    • 0026780338 scopus 로고
    • Renal cell carcinoma: Incidental diagnosis and natural history: Review of 235 cases
    • Mevorach RA, Segal AJ, Tersegno ME, Frank IN. Renal cell carcinoma: incidental diagnosis and natural history: review of 235 cases. Urology 39(6), 519-522 (1992).
    • (1992) Urology , vol.39 , Issue.6 , pp. 519-522
    • Mevorach, R.A.1    Segal, A.J.2    Tersegno, M.E.3    Frank, I.N.4
  • 5
    • 0036135224 scopus 로고    scopus 로고
    • Increasing incidence of all stages of kidney cancer in the last 2 decades in the United States: An analysis of surveillance, epidemiology and end results program data
    • Hock LM, Lynch J, Balaji KC. Increasing incidence of all stages of kidney cancer in the last 2 decades in the United States: an analysis of surveillance, epidemiology and end results program data. J. Urol. 167(1), 57-60 (2002).
    • (2002) J. Urol , vol.167 , Issue.1 , pp. 57-60
    • Hock, L.M.1    Lynch, J.2    Balaji, K.C.3
  • 6
    • 0034796962 scopus 로고    scopus 로고
    • The changing natural history of renal cell carcinoma
    • Pantuck AJ, Zisman A, Belldegrun AS. The changing natural history of renal cell carcinoma. J. Urol. 166(5), 1611-1623 (2001).
    • (2001) J. Urol , vol.166 , Issue.5 , pp. 1611-1623
    • Pantuck, A.J.1    Zisman, A.2    Belldegrun, A.S.3
  • 7
    • 0037428774 scopus 로고    scopus 로고
    • Metastatic renal carcinoma comprehensive prognostic system
    • Atzpodien J, Royston P, Wandert T, Reitz M. Metastatic renal carcinoma comprehensive prognostic system. Br. J. Cancer 88(3), 348-353 (2003).
    • (2003) Br. J. Cancer , vol.88 , Issue.3 , pp. 348-353
    • Atzpodien, J.1    Royston, P.2    Wandert, T.3    Reitz, M.4
  • 8
    • 0037407573 scopus 로고    scopus 로고
    • Blute ML. Comparisons of outcome and prognostic features among histologic subtypes of renal cell carcinoma
    • Cheville JC, Lohse CM, Zincke H, Weaver AL, Blute ML. Comparisons of outcome and prognostic features among histologic subtypes of renal cell carcinoma. Am. J. Surg. Pathol. 27(5), 612-624 (2003).
    • (2003) Am. J. Surg. Pathol , vol.27 , Issue.5 , pp. 612-624
    • Cheville, J.C.1    Lohse, C.M.2    Zincke, H.3    Weaver, A.L.4
  • 10
    • 0033978220 scopus 로고    scopus 로고
    • Systemic therapy for renal cell carcinoma
    • Motzer RJ, Russo P. Systemic therapy for renal cell carcinoma. J. Urol. 163(2), 408-417 (2003).
    • (2003) J. Urol , vol.163 , Issue.2 , pp. 408-417
    • Motzer, R.J.1    Russo, P.2
  • 11
    • 45949105138 scopus 로고    scopus 로고
    • Treatment options in renal cell carcinoma: Past, present and future
    • Oudard S, George D, Medioni J et al. Treatment options in renal cell carcinoma: past, present and future. Ann. Oncol. 18(Suppl. 10), 25-31 (2007).
    • (2007) Ann. Oncol , vol.18 , pp. 25-31
    • Oudard, S.1    George, D.2    Medioni, J.3
  • 12
    • 4644335916 scopus 로고    scopus 로고
    • McDermott D. Update on the role of interleukin 2 and other cytokines in the treatment of patients with stage IV renal carcinoma
    • Atkins MB, Regan M, McDermott D. Update on the role of interleukin 2 and other cytokines in the treatment of patients with stage IV renal carcinoma. Clin. Cancer. Res. 10(Suppl.), 6342-6346 (2004).
    • (2004) Clin. Cancer. Res , vol.10 , pp. 6342-6346
    • Atkins, M.B.1    Regan, M.2
  • 13
    • 79955845255 scopus 로고    scopus 로고
    • Targeted Therapies for the Treatment of Metastatic Renal Cell Carcinoma
    • Hutson TE. Targeted Therapies for the Treatment of Metastatic Renal Cell Carcinoma: Clinical Evidence. The Oncologist 16(Suppl. 2), 14-22 (2011).
    • (2011) Clinical Evidence. the Oncologist , vol.16 , pp. 14-22
    • Hutson, T.E.1
  • 14
    • 58949092548 scopus 로고    scopus 로고
    • Sequential therapy with sorafenib and sunitinib in renal cell carcinoma
    • Dudek AZ, Zolnierek J, Dham A, Lindgren BR, Szczylik C. Sequential therapy with sorafenib and sunitinib in renal cell carcinoma. Cancer 115(1), 61-67 (2009).
    • (2009) Cancer , vol.115 , Issue.1 , pp. 61-67
    • Dudek, A.Z.1    Zolnierek, J.2    Dham, A.3    Lindgren, B.R.4    Szczylik, C.5
  • 15
    • 48649107474 scopus 로고    scopus 로고
    • Efficacy of everolimus in advanced renal cell carcinoma: A double-blind, randomised, placebo-controlled Phase III trial
    • Motzer RJ, Escudier B, Oudard S et al. Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled Phase III trial. Lancet 372(9637), 449-456 (2008).
    • (2008) Lancet , vol.372 , Issue.9637 , pp. 449-456
    • Motzer, R.J.1    Escudier, B.2    Oudard, S.3
  • 17
    • 79957802759 scopus 로고    scopus 로고
    • Final results of the European Advanced Renal Cell Carcinoma Sorafenib (EU-ARCCS) expanded-access study: A large openlabel study in diverse community settings
    • Beck J, Procopio G, Bajetta E et al. Final results of the European Advanced Renal Cell Carcinoma Sorafenib (EU-ARCCS) expanded-access study: a large openlabel study in diverse community settings. Ann. Oncol. 22(8), 1812-1823 (2011).
    • (2011) Ann. Oncol , vol.22 , Issue.8 , pp. 1812-1823
    • Beck, J.1    Procopio, G.2    Bajetta, E.3
  • 18
    • 34648813908 scopus 로고    scopus 로고
    • Managing side effects of angiogenesis inhibitors in RCC
    • Grünwald V, Heinzer H, Fiedler W. Managing side effects of angiogenesis inhibitors in RCC. Onkologie 30, 519-524 (2007).
    • (2007) Onkologie , vol.30 , pp. 519-524
    • Grünwald, V.1    Heinzer, H.2    Fiedler, W.3
  • 19
    • 41949101493 scopus 로고    scopus 로고
    • Novel therapies in advanced renal cell carcinoma: Management of adverse events from sorafenib and sunitinib
    • Ivanyi P, Winkler T, Ganser A, Reuter C, Grünwald V. Novel therapies in advanced renal cell carcinoma: management of adverse events from sorafenib and sunitinib. Dtsch. Arztebl. Int. 105(13), 232-237 (2008).
    • (2008) Dtsch. Arztebl. Int , vol.105 , Issue.13 , pp. 232-237
    • Ivanyi, P.1    Winkler, T.2    Ganser, A.3    Reuter, C.4    Grünwald, V.5
  • 20
    • 85041065991 scopus 로고    scopus 로고
    • Sequential use of sorafenib (So) followed by sunitinib (Su) in metastatic renal cell cancer (mRCC): A single-institution experience [abstract]
    • Orlando, FL, USA
    • Procopio G, Verzoni E, Guadalupi V et al. Sequential use of sorafenib (So) followed by sunitinib (Su) in metastatic renal cell cancer (mRCC): a single-institution experience [abstract]. Presented at: Genitourinary Cancers Symposium. Orlando, FL, USA, 26-28 February 2009 (Abstract 319).
    • (2009) Presented At: Genitourinary Cancers Symposium , pp. 26-28
    • Procopio, G.1    Verzoni, E.2    Guadalupi, V.3
  • 21
    • 0032772880 scopus 로고    scopus 로고
    • Survival and prognostic stratification of 670 patients with advanced renal cell carcinoma
    • Motzer RJ, Mazumdar M, Bacik J, Berg W, Amsterdam A, Ferrara J. Survival and prognostic stratification of 670 patients with advanced renal cell carcinoma. J. Clin. Oncol. 17(8), 2530-2540 (1999).
    • (1999) J. Clin. Oncol , vol.17 , Issue.8 , pp. 2530-2540
    • Motzer, R.J.1    Mazumdar, M.2    Bacik, J.3    Berg, W.4    Amsterdam, A.5    Ferrara, J.6
  • 22
    • 58649083487 scopus 로고    scopus 로고
    • From randomized controlled trials to observational studies
    • Silverman SL. From randomized controlled trials to observational studies. Am. J. Med. 122(2), 114-120 (2009).
    • (2009) Am. J. Med , vol.122 , Issue.2 , pp. 114-120
    • Silverman, S.L.1
  • 23
    • 85041037088 scopus 로고    scopus 로고
    • Sequencing tyrosine kinase inhibitors or immediately switching to mTOR inhibitors in advanced kidney cancer: A critical review
    • Porta C, Paglino C, Cartenì G et al. Sequencing tyrosine kinase inhibitors or immediately switching to mTOR inhibitors in advanced kidney cancer: a critical review. EJCMO (2011) (In Press).
    • (2011) EJCMO
    • Porta, C.1    Paglino, C.2    Cartenì, G.3
  • 24
    • 55649103188 scopus 로고    scopus 로고
    • Sequential use of the tyrosine kinase inhibitors sorafenib and sunitinib in metastatic renal cell carcinoma: A retrospective outcome analysis
    • Eichelberg C, Heuer R, Chun FK et al. Sequential use of the tyrosine kinase inhibitors sorafenib and sunitinib in metastatic renal cell carcinoma: a retrospective outcome analysis. Eur. Urol. 54(6), 1373-1378 (2008).
    • (2008) Eur. Urol , vol.54 , Issue.6 , pp. 1373-1378
    • Eichelberg, C.1    Heuer, R.2    Chun, F.K.3
  • 25
    • 67349163859 scopus 로고    scopus 로고
    • Sequential sorafenib and sunitinib for renal cell carcinoma
    • Sablin MP, Negrier S, Ravaud A et al. Sequential sorafenib and sunitinib for renal cell carcinoma. J. Urol. 182, 29-34 (2009).
    • (2009) J. Urol , vol.182 , pp. 29-34
    • Sablin, M.P.1    Negrier, S.2    Ravaud, A.3
  • 26
    • 62849099971 scopus 로고    scopus 로고
    • Sunitinib treatment for patients with advanced clear cell renal-cell carcinoma after progression on sorafenib
    • Zimmerman K, Schmittel A, Steiner U et al. Sunitinib treatment for patients with advanced clear cell renal-cell carcinoma after progression on sorafenib. Oncology 76(5), 350-354 (2009).
    • (2009) Oncology , vol.76 , Issue.5 , pp. 350-354
    • Zimmerman, K.1    Schmittel, A.2    Steiner, U.3
  • 27
    • 77955895649 scopus 로고    scopus 로고
    • Sorafenib in patients with metastatic renal cell carcinoma refractory to either sunitinib or bevacizumab
    • Garcia JA, Hutson TE, Elson P et al. Sorafenib in patients with metastatic renal cell carcinoma refractory to either sunitinib or bevacizumab. Cancer 116(23), 5383-5390 (2010).
    • (2010) Cancer , vol.116 , Issue.23 , pp. 5383-5390
    • Garcia, J.A.1    Hutson, T.E.2    Elson, P.3
  • 28
    • 85041074692 scopus 로고    scopus 로고
    • NCCN Clinical Practice Guidelines in Oncology™Kidney Cancer. Version 2.2010. © 2009 National Comprehensive Cancer Network, Inc, (Accessed 20 March 2011)
    • NCCN Clinical Practice Guidelines in Oncology™Kidney Cancer. Version 2.2010. © 2009 National Comprehensive Cancer Network, Inc www.nccn.org/professionals/physician_gls/f_guidelines.asp#site (Accessed 20 March 2011)
  • 29
    • 85041045009 scopus 로고    scopus 로고
    • ClinicalTrials.gov. NCT00631371. Study Comparing Bevacizumab + Temsirolimus vs Bevacizumab + Interferon-Alfa in Advanced Renal Cell Carcinoma Subjects (INTORACT, (Accessed 22 March 2011)
    • ClinicalTrials.gov. NCT00631371. Study Comparing Bevacizumab + Temsirolimus vs Bevacizumab + Interferon-Alfa in Advanced Renal Cell Carcinoma Subjects (INTORACT) www.clinicaltrials.gov/ct2/show/NCT006 31371?term=NCT00631371&rank=1 (Accessed 22 March 2011)
  • 30
    • 85041080763 scopus 로고    scopus 로고
    • ClinicalTrials.gov. NCT00378703. Bevacizumab, Sorafenib, and Temsirolimus in Treating Patients With Metastatic Kidney Cancer, (Accessed 22 March 2011)
    • ClinicalTrials.gov. NCT00378703. Bevacizumab, Sorafenib, and Temsirolimus in Treating Patients With Metastatic Kidney Cancer www.clinicaltrials.gov/ct2/show/NCT003 78703?term=NCT00378703&rank=1 (Accessed 22 March 2011)
  • 31
    • 85041041525 scopus 로고    scopus 로고
    • ClinicalTrials.gov. NCT00619268. Combination of Temsirolimus and Bevacizumab in Patients with Metastatic Renal Cell Carcinoma (TORAVA), (Accessed 22 March 2011)
    • ClinicalTrials.gov. NCT00619268. Combination of Temsirolimus and Bevacizumab in Patients with Metastatic Renal Cell Carcinoma (TORAVA) www.clinicaltrials.gov/ct2/show/NCT006 19268?term=NCT00619268&rank=1 (Accessed 22 March 2011)
  • 32
    • 85041091104 scopus 로고    scopus 로고
    • ClinicalTrials.gov. NCT00719264. Safety and Efficacy of Bevacizumab Plus RAD 001 Versus Interferon Alfa-2a and Bevacizumab in Adult Patients With Kidney Cancer, (Accessed 22 March 2011)
    • ClinicalTrials.gov. NCT00719264. Safety and Efficacy of Bevacizumab Plus RAD 001 Versus Interferon Alfa-2a and Bevacizumab in Adult Patients With Kidney Cancer www.clinicaltrials.gov/ct2/show/NCT007 19264?term=NCT00719264&rank=1 (Accessed 22 March 2011)
  • 33
    • 37549072095 scopus 로고    scopus 로고
    • NCCN Clinical Practice Guidelines in Oncology
    • Accessed 22 March 2011
    • National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology. Kidney Cancer. V. 2.2010 www.nccn.org/professionals/physician_gls/PDF/kidney.pdf (Accessed 22 March 2011)
    • (2010) Kidney Cancer , vol.5 , pp. 2
  • 35
    • 85041077189 scopus 로고    scopus 로고
    • ClinicalTrials.gov. NCT00732914. A Phase III Randomized Sequential Open-Label Study to Evaluate the Efficacy and Safety of Sorafenib Followed by Sunitinib Versus Sunitinib Followed by Sorafenib in the Treatment of First-Line Advanced/Metastatic Renal Cell Carcinoma, (Accessed 22 March 2011)
    • ClinicalTrials.gov. NCT00732914. A Phase III Randomized Sequential Open-Label Study to Evaluate the Efficacy and Safety of Sorafenib Followed by Sunitinib Versus Sunitinib Followed by Sorafenib in the Treatment of First-Line Advanced/Metastatic Renal Cell Carcinoma http://clinicaltrials.gov/ct2/show/NCT00732914 (Accessed 22 March 2011)
  • 36
    • 85041084531 scopus 로고    scopus 로고
    • Common Terminology Criteria for Adverse Events v3.0 (CTCAE), (Accessed 22 March 2011)
    • Common Terminology Criteria for Adverse Events v3.0 (CTCAE) http://ctep.cancer.gov/protocolDevelopment/electronic_applications/docs/ctcaev3.pdf (Accessed 22 March 2011)
  • 37
    • 85041055886 scopus 로고    scopus 로고
    • ClinicalTrials.gov, (Accessed 25 August 2011)
    • ClinicalTrials.gov http://clinicaltrials.gov/ct2/show/NCT00930033 (Accessed 25 August 2011)
  • 38
    • 85041044244 scopus 로고    scopus 로고
    • EORTC protocol 30073-SURTIME, (Accessed 25 August 2011)
    • EORTC protocol 30073-SURTIME www.eortc.be/protoc/details.asp?protocol=30073 (Accessed 25 August 2011)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.