Low-grade inflammation, but not endothelial dysfunction, is associated with greater carotid stiffness in the elderly: The Hoorn Study

Journal of Hypertension

Volumn 30, Issue 4, 2012, Pages 744-752

  Van Bussel, Bas C T ^a,b,c   Henry, Ronald M A ^a,c,d   Schalkwijk, Casper G ^a,c,d   Dekker, Jacqueline M ^e,f   Nijpels, Giel ^e,g   Stehouwer, Coen D A ^a,b,c,d  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c TOP INSTITUTE FOOD AND NUTRITION   (Netherlands)

^d MAASTRICHT UNIVERSITY   (Netherlands)

^e UNIVERSITY OF AMSTERDAM   (Netherlands)

^f NONE   (Netherlands)

^g VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

arterial stiffness; elderly individuals; endothelial dysfunction; epidemiology; inflammation

Indexed keywords

ANTIHYPERTENSIVE AGENT; ANTILIPEMIC AGENT; C REACTIVE PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; INTERLEUKIN 8; SELECTIN; SERUM AMYLOID A; THROMBOMODULIN; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1; VON WILLEBRAND FACTOR;

ADULT; AGED; ARTERIAL STIFFNESS; ARTERIAL WALL THICKNESS; ARTERY COMPLIANCE; ARTERY DIAMETER; ARTERY DILATATION; ARTICLE; CARDIOVASCULAR DISEASE; CAROTID ARTERY; DISEASE ASSOCIATION; ECHOGRAPHY; ENDOTHELIAL DYSFUNCTION; FEMALE; GLUCOSE TOLERANCE; HUMAN; HYPERTENSION; INFLAMMATION; LOW GRADE INFLAMMATION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PULSE PRESSURE; SMOKING; YOUNG MODULUS;

EID: 84858709227     PISSN: 02636352     EISSN: 14735598     Source Type: Journal    
DOI: 10.1097/HJH.0b013e328350a487     Document Type: Article

References (40)

1. Becker A, van Hinsbergh VW, Jager A, Kostense PJ, Dekker JM, Nijpels G, et al. Why is soluble intercellular adhesion molecule-1 related to cardiovascular mortality? Eur J Clin Invest 2002; 32:1-8. (Pubitemid 36228376)
2. Blankenberg S, Rupprecht HJ, Bickel C, Peetz D, Hafner G, Tiret L, Meyer J. Circulating cell adhesion molecules and death in patients with coronary artery disease. Circulation 2001; 104:1336-1342. (Pubitemid 32880144)
3. de Jager J, Dekker JM, Kooy A, Kostense PJ, Nijpels G, Heine RJ, et al. Endothelial dysfunction and low-grade inflammation explain much of the excess cardiovascular mortality in individuals with type 2 diabetes: the Hoorn Study. Arterioscler Thromb Vasc Biol 2006; 26:1086-1093. (Pubitemid 43732116)
4. Jager A, van Hinsbergh VW, Kostense PJ, Emeis JJ, Yudkin JS, Nijpels G, et al. von Willebrand factor, C-reactive protein, and 5-year mortality in diabetic and nondiabetic subjects: the Hoorn Study. Arterioscler Thromb Vasc Biol 1999; 19:3071-3078. (Pubitemid 30029838)
5. Morange PE, Simon C, Alessi MC, Luc G, Arveiler D, Ferrieres J, et al. Endothelial cell markers and the risk of coronary heart disease: the Prospective Epidemiological Study of Myocardial Infarction (PRIME) study. Circulation 2004; 109:1343-1348. (Pubitemid 38387818)
6. Ridker PM, Hennekens CH, Buring JE, Rifai N. C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. N Engl J Med 2000; 342:836-843. (Pubitemid 30165206)
7. Yeboah J, Crouse JR, Hsu FC, Burke GL, Herrington DM. Brachial flow-mediated dilation predicts incident cardiovascular events in older adults: the Cardiovascular Health Study. Circulation 2007; 115:2390-2397. (Pubitemid 46717961)
8. Ross R. Atherosclerosis: an inflammatory disease. N Engl J Med 1999; 340:115-126.
9. Borissoff JI, Spronk HM, ten Cate H. The hemostatic system as a modulator of atherosclerosis. N Engl J Med 2011; 364:1746-1760.
10. Schnabel R, Larson MG, Dupuis J, Lunetta KL, Lipinska I, Meigs JB, et al. Relations of inflammatory biomarkers and common genetic variants with arterial stiffness and wave reflection. Hypertension 2008; 51:1651-1657.
11. Lieb W, Larson MG, Benjamin EJ, Yin X, Tofler GH, Selhub J, et al. Multimarker approach to evaluate correlates of vascular stiffness: the Framingham Heart Study. Circulation 2009; 119:37-43.
12. Yasmin, McEniery CM, Wallace S, Mackenzie IS, Cockcroft JR, Wilkinson IB. C-reactive protein is associated with arterial stiffness in apparently healthy individuals. Arterioscler Thromb Vasc Biol 2004; 24:969-974. (Pubitemid 38620880)
13. Amar J, Ruidavets JB, Bal Dit Sollier C, Bongard V, Boccalon H, Chamontin B, et al. Soluble CD14 and aortic stiffness in a population-based study. J Hypertens 2003; 21:1869-1877. (Pubitemid 37290105)
14. van Bussel BC, Schouten F, Henry RM, Schalkwijk CG, de Boer MR, Ferreira I, et al. Endothelial dysfunction and low-grade inflammation are associated with greater arterial stiffness over a 6-year period. Hypertension 2011; 58:588-595.
15. Mattace-Raso FU, van der Cammen TJ, van der Meer IM, Schalekamp MA, Asmar R, Hofman A, Witteman JC. C-reactive protein and arterial stiffness in older adults: the Rotterdam Study. Atherosclerosis 2004; 176:111-116. (Pubitemid 39078652)
16. Juonala M, Jarvisalo MJ, Maki-Torkko N, Kahonen M, Viikari JS, Raitakari OT. Risk factors identified in childhood and decreased carotid artery elasticity in adulthood: the Cardiovascular Risk in Young Finns Study. Circulation 2005; 112:1486-1493. (Pubitemid 41291774)
17. Eklund C, Kivimaki M, Islam MS, Juonala M, Kahonen M, Marniemi J, et al. C-reactive protein genetics is associated with carotid artery compliance in men in The Cardiovascular Risk in Young Finns Study. Atherosclerosis 2008; 196:841-848.
18. Mooy JM, Grootenhuis PA, de Vries H, Valkenburg HA, Bouter LM, Kostense PJ, Heine RJ. Prevalence and determinants of glucose intolerance in a Dutch caucasian population. The Hoorn Study. Diabetes Care 1995; 18:1270-1273.
19. Spijkerman AM, Adriaanse MC, Dekker JM, Nijpels G, Stehouwer CD, Bouter LM, Heine RJ. Diabetic patients detected by population-based stepwise screening already have a diabetic cardiovascular risk profile. Diabetes Care 2002; 25:1784-1789. (Pubitemid 41071087)
20. Henry RM, Kostense PJ, Spijkerman AM, Dekker JM, Nijpels G, Heine RJ, et al. Arterial stiffness increases with deteriorating glucose tolerance status: the Hoorn Study. Circulation 2003; 107:2089-2095. (Pubitemid 36532189)
21. de Valk-de Roo GW, Stehouwer CD, Lambert J, Schalkwijk CG, van der Mooren MJ, Kluft C, Netelenbos C. Plasma homocysteine is weakly correlated with plasma endothelin and von Willebrand factor but not with endothelium-dependent vasodilatation in healthy postmenopausal women. Clin Chem 1999; 45:1200-1205. (Pubitemid 29424258)
22. Henry RM, Ferreira I, Kostense PJ, Dekker JM, Nijpels G, Heine RJ, et al. Type 2 diabetes is associated with impaired endothelium-dependent, flow-mediated dilation, but impaired glucose metabolism is not: The Hoorn Study. Atherosclerosis 2004; 174:49-56. (Pubitemid 38595439)
23. Laurent S, Cockcroft J, Van Bortel L, Boutouyrie P, Giannattasio C, Hayoz D, et al. Expert consensus document on arterial stiffness: methodological issues and clinical applications. Eur Heart J 2006; 27:2588-2605. (Pubitemid 44627304)
24. Van Bortel LM, Balkestein EJ, van der Heijden-Spek JJ, Vanmolkot FH, Staessen JA, Kragten JA, et al. Noninvasive assessment of local arterial pulse pressure: comparison of applanation tonometry and echo-tracking. J Hypertens 2001; 19:1037-1044. (Pubitemid 32493636)
25. Levey AS, Coresh J, Greene T, Marsh J, Stevens LA, Kusek JW, Van Lente F. Expressing the Modification of Diet in Renal Disease Study equation for estimating glomerular filtration rate with standardized serum creatinine values. Clin Chem 2007; 53:766-772. (Pubitemid 46580250)
26. Yudkin JS, Stehouwer CD, Emeis JJ, Coppack SW. C-reactive protein in healthy subjects: associations with obesity, insulin resistance, and endothelial dysfunction-a potential role for cytokines originating from adipose tissue? Arterioscler Thromb Vasc Biol 1999; 19:972-978. (Pubitemid 29177345)
27. Schram MT, Stehouwer CD. Endothelial dysfunction, cellular adhesion molecules and the metabolic syndrome. Horm Metab Res 2005; 37 (Suppl 1):49-55.
28. Wohlin M, Helmersson J, Sundstrom J, Arnlov J, Vessby B, Larsson A, et al. Both cyclooxygenase-and cytokine-mediated inflammation are associated with carotid intima-media thickness. Cytokine 2007; 38:130-136. (Pubitemid 47248296)
29. Leinonen ES, Hiukka A, Hurt-Camejo E, Wiklund O, Sarna SS, Mattson Hulten L, et al. Low-grade inflammation, endothelial activation and carotid intima-media thickness in type 2 diabetes. J Intern Med 2004; 256:119-127. (Pubitemid 38998258)
30. Schillinger M, Exner M, Mlekusch W, Sabeti S, Amighi J, Nikowitsch R, et al. Inflammation and Carotid Artery: Risk for Atherosclerosis Study (ICARAS). Circulation 2005; 111:2203-2209. (Pubitemid 40632436)
31. Stehouwer CD, Henry RM, Ferreira I. Arterial stiffness in diabetes and the metabolic syndrome: a pathway to cardiovascular disease. Diabetologia 2008; 51:527-539.
32. van Dijk RA, Dekker JM, Nijpels G, Heine RJ, Bouter LM, Stehouwer CD. Brachial artery pulse pressure and common carotid artery diameter: mutually independent associations with mortality in subjects with a recent history of impaired glucose tolerance. Eur J Clin Invest 2001; 31:756-763. (Pubitemid 34203469)
33. Aird WC. Phenotypic heterogeneity of the endothelium. I: Structure, function, and mechanisms. Circ Res 2007; 100:158-173. (Pubitemid 46208717)
34. Aird WC. Phenotypic heterogeneity of the endothelium. II: Representative vascular beds. Circ Res 2007; 100:174-190. (Pubitemid 46208718)
35. Deanfield J, Donald A, Ferri C, Giannattasio C, Halcox J, Halligan S, et al. Endothelial function and dysfunction. Part I: Methodological issues for assessment in the different vascular beds-a statement by the Working Group on Endothelin and Endothelial Factors of the European Society of Hypertension. J Hypertens 2005; 23: 7-17. (Pubitemid 40128972)
36. Thijssen DH, Black MA, Pyke KE, Padilla J, Atkinson G, Harris RA, et al. Assessment of flow mediated dilation (FMD) in humans: a methodological and technical guideline. Am J Physiol Heart Circ Physiol 2011; 300:H2-H12.
37. Vischer UM. von Willebrand factor, endothelial dysfunction, and cardiovascular disease. J Thromb Haemost 2006; 4:1186-1193.
38. McEniery CM, Wallace S, Mackenzie IS, McDonnell B, Yasmin, Newby DE, et al. Endothelial function is associated with pulse pressure, pulse wave velocity, and augmentation index in healthy humans. Hypertension 2006; 48:602-608. (Pubitemid 44843862)
39. Hartweg J, Gunter M, Perera R, Farmer A, Cull C, Schalkwijk C, et al. Stability of soluble adhesion molecules, selectins, and C-reactive protein at various temperatures: implications for epidemiological and large-scale clinical studies. Clin Chem 2007; 53:1858-1860. (Pubitemid 47509682)
40. Hutchinson WL, Koenig W, Frohlich M, Sund M, Lowe GD, Pepys MB. Immunoradiometric assay of circulating C-reactive protein: age-related values in the adult general population. Clin Chem 2000; 46:934-938. (Pubitemid 30461263)