Rapid clearance of supplemented tetrahydrobiopterin is driven by high-capacity transporters in the kidney

Molecular Genetics and Metabolism

Volumn 105, Issue 4, 2012, Pages 575-581

  Ohashi, Akiko ^a   Suetake, Yasuko ^b   Saeki, Yusuke ^b   Harada, Tomonori ^a   Aizawa, Shin ^a   Hasegawa, Hiroyuki ^a  

^a NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b TEIKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

Organic anion transporter; P glycoprotein; Plasma biopterin; Tetrahydrobiopterin; Urinary biopterin

Indexed keywords

CYCLOSPORIN A; TETRAHYDROBIOPTERIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG UPTAKE; FEMALE; GLOMERULUS FILTRATION; KIDNEY TUBULE EXCRETION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; URINARY EXCRETION;

ANIMALS; BIOPTERIN; DIETARY SUPPLEMENTS; GLOMERULAR FILTRATION RATE; KIDNEY; KINETICS; MALE; MICE; MICE, INBRED C57BL; PHENYLKETONURIAS; RATS; RATS, SPRAGUE-DAWLEY;

RATTUS;

EID: 84858699266     PISSN: 10967192     EISSN: 10967206     Source Type: Journal    
DOI: 10.1016/j.ymgme.2012.01.009     Document Type: Article

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