Enterotoxin-producing staphylococci cause intestinal inflammation by a combination of direct epithelial cytopathy and superantigen-mediated T-cell activation

Inflammatory Bowel Diseases

Volumn 18, Issue 4, 2012, Pages 624-640

  Edwards, Lindsey A ^a,b   O'Neill, Colette ^c   Furman, Mark A ^a   Hicks, Susan ^a   Torrente, Franco ^a   Pérez Machado, Miguel ^a   Wellington, Elizabeth M ^b   Phillips, Alan D ^a   Murch, Simon H ^d  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF WARWICK   (United Kingdom)

^d UNIVERSITY OF WARWICK   (United Kingdom)

Author keywords

Enterotoxins; Epithelial cytotoxicity; Inflammatory bowel disease; Staphylococcus aureus; Superantigens

Indexed keywords

BETA DEFENSIN; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; HBD2 PROTEIN; HBD3 PROTEIN; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; MESSENGER RNA; STAPHYLOCOCCUS ENTEROTOXIN; SUPERANTIGEN; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL IMMUNITY; CASE REPORT; CELL STRAIN CACO 2; CELLULAR IMMUNITY; COLON MUCOSA; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; CYTOTOXICITY; DESQUAMATION; DUODENUM BIOPSY; ELECTRON MICROSCOPY; ENTEROCOLITIS; ENTEROCYTE CYTOPATHY; EPITHELIUM CELL; FEMALE; HEP 2 CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPATHOGENESIS; IN VITRO STUDY; INFANT; INTESTINE ISCHEMIA; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MUCOSAL IMMUNITY; ORGAN CULTURE; PRIORITY JOURNAL; STAPHYLOCOCCUS INFECTION; T LYMPHOCYTE ACTIVATION;

BETA-DEFENSINS; BIOPSY; CELL LINE; COCULTURE TECHNIQUES; ENTEROCOLITIS; ENTEROTOXINS; FEMALE; HUMANS; INFANT; INTESTINAL MUCOSA; LYMPHOCYTE ACTIVATION; MALE; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; SUPERANTIGENS; T-LYMPHOCYTES; TACROLIMUS;

EID: 84858698108     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1002/ibd.21852     Document Type: Article

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