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Volumn 33, Issue 2, 2012, Pages 47-50

Physiologically based pharmacokinetic (PBPK) modeling: It is here to stay!

Author keywords

[No Author keywords available]

Indexed keywords

XENOBIOTIC AGENT;

EID: 84858697961     PISSN: 01422782     EISSN: 1099081X     Source Type: Journal    
DOI: 10.1002/bdd.1776     Document Type: Note
Times cited : (30)

References (9)
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    • Applications of physiologically based pharmacokinetic (PBPK) modeling and simulation during regulatory review
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    • (2011) Clin Pharmacol Ther , vol.89 , pp. 259-267
    • Zhao, P.1    Zhang, L.2    Grillo, J.A.3
  • 2
    • 79951615778 scopus 로고    scopus 로고
    • Resurgence in the use of physiologically based pharmacokinetic models in pediatric clinical pharmacology: Parallel shift in incorporating the knowledge of biological elements and increased applicability to drug development and clinical practice
    • Johnson TN, Rostami-Hodjegan A. Resurgence in the use of physiologically based pharmacokinetic models in pediatric clinical pharmacology: parallel shift in incorporating the knowledge of biological elements and increased applicability to drug development and clinical practice. Paediatr Anaesth 2011; 21: 291-301.
    • (2011) Paediatr Anaesth , vol.21 , pp. 291-301
    • Johnson, T.N.1    Rostami-Hodjegan, A.2
  • 3
    • 79951765993 scopus 로고    scopus 로고
    • Physiologically-based pharmacokinetics in drug development and regulatory science
    • Rowland M, Peck C, Tucker G. Physiologically-based pharmacokinetics in drug development and regulatory science. Annu Rev Pharmacol Toxicol 2011; 51: 45-73.
    • (2011) Annu Rev Pharmacol Toxicol , vol.51 , pp. 45-73
    • Rowland, M.1    Peck, C.2    Tucker, G.3
  • 4
    • 84858699365 scopus 로고    scopus 로고
    • Physiologically based pharmacokinetic (PBPK) modelling tools: How to fit with our needs?
    • Bouzom F, Ball K, Perdaems N, Walther B. Physiologically based pharmacokinetic (PBPK) modelling tools: how to fit with our needs? Biopharm Drug Dispos 2012; 55-71.
    • (2012) Biopharm Drug Dispos , pp. 55-71
    • Bouzom, F.1    Ball, K.2    Perdaems, N.3    Walther, B.4
  • 5
    • 84862777396 scopus 로고    scopus 로고
    • Application of IVIVE and PBPK modeling in prospective prediction of clinical pharmacokinetics: Strategy and approach during the drug discovery phase with four case studies
    • Chen Y, Jin JY, Mukadam S, Malhi V, Kenny JR. Application of IVIVE and PBPK modeling in prospective prediction of clinical pharmacokinetics: strategy and approach during the drug discovery phase with four case studies. Biopharm Drug Dispos 2012; 85-98.
    • (2012) Biopharm Drug Dispos , pp. 85-98
    • Chen, Y.1    Jin, J.Y.2    Mukadam, S.3    Malhi, V.4    Kenny, J.R.5
  • 6
    • 84858704368 scopus 로고    scopus 로고
    • Using Simcyp to project human oral pharmacokinetic variability in early drug research to mitigate mechanism-based adverse events
    • Shaffer CL, Scialis RJ, Rong H, Obach RS. Using Simcyp to project human oral pharmacokinetic variability in early drug research to mitigate mechanism-based adverse events. Biopharm Drug Dispos 2012; 72-84.
    • (2012) Biopharm Drug Dispos , pp. 72-84
    • Shaffer, C.L.1    Scialis, R.J.2    Rong, H.3    Obach, R.S.4
  • 7
    • 84858660647 scopus 로고    scopus 로고
    • From preclinical to human - Prediction of oral absorption and drug-drug interaction potential using physiologically based pharmacokinetic (PBPK) modeling approach in industrial setting: A workflow by using case example
    • Sinha VK, Snoeys J, Van Osselaer N, Van Peer A, Mackie C, Heald D. From preclinical to human - prediction of oral absorption and drug-drug interaction potential using physiologically based pharmacokinetic (PBPK) modeling approach in industrial setting: a workflow by using case example. Biopharm Drug Dispos 2012; 111-121.
    • (2012) Biopharm Drug Dispos , pp. 111-121
    • Sinha, V.K.1    Snoeys, J.2    Van Osselaer, N.3    Van Peer, A.4    Mackie, C.5    Heald, D.6
  • 8
    • 84862777920 scopus 로고    scopus 로고
    • The role of physiologically based pharmacokinetic modeling in regulatory review
    • Huang SM, Rowland M. The role of physiologically based pharmacokinetic modeling in regulatory review. Clin Pharmacol Ther 2012; 91: 542-549.
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    • Huang, S.M.1    Rowland, M.2
  • 9
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    • Utility of a physiologically-based pharmacokinetic (PBPK) modeling approach to quantitatively predict a complex drug-drug-disease interaction scenario with rivaroxaban during the drug review process: Implications for clinical practice
    • Grillo JA, Zhao P, Bullock J, et al. Utility of a physiologically-based pharmacokinetic (PBPK) modeling approach to quantitatively predict a complex drug-drug-disease interaction scenario with rivaroxaban during the drug review process: implications for clinical practice. Biopharm Drug Dispos 2012; 99-110.
    • (2012) Biopharm Drug Dispos , pp. 99-110
    • Grillo, J.A.1    Zhao, P.2    Bullock, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.