-
1
-
-
78951482203
-
Applications of physiologically based pharmacokinetic (PBPK) modeling and simulation during regulatory review
-
Zhao P, Zhang L, Grillo JA, et al. Applications of physiologically based pharmacokinetic (PBPK) modeling and simulation during regulatory review. Clin Pharmacol Ther 2011; 89: 259-267.
-
(2011)
Clin Pharmacol Ther
, vol.89
, pp. 259-267
-
-
Zhao, P.1
Zhang, L.2
Grillo, J.A.3
-
2
-
-
79951615778
-
Resurgence in the use of physiologically based pharmacokinetic models in pediatric clinical pharmacology: Parallel shift in incorporating the knowledge of biological elements and increased applicability to drug development and clinical practice
-
Johnson TN, Rostami-Hodjegan A. Resurgence in the use of physiologically based pharmacokinetic models in pediatric clinical pharmacology: parallel shift in incorporating the knowledge of biological elements and increased applicability to drug development and clinical practice. Paediatr Anaesth 2011; 21: 291-301.
-
(2011)
Paediatr Anaesth
, vol.21
, pp. 291-301
-
-
Johnson, T.N.1
Rostami-Hodjegan, A.2
-
3
-
-
79951765993
-
Physiologically-based pharmacokinetics in drug development and regulatory science
-
Rowland M, Peck C, Tucker G. Physiologically-based pharmacokinetics in drug development and regulatory science. Annu Rev Pharmacol Toxicol 2011; 51: 45-73.
-
(2011)
Annu Rev Pharmacol Toxicol
, vol.51
, pp. 45-73
-
-
Rowland, M.1
Peck, C.2
Tucker, G.3
-
4
-
-
84858699365
-
Physiologically based pharmacokinetic (PBPK) modelling tools: How to fit with our needs?
-
Bouzom F, Ball K, Perdaems N, Walther B. Physiologically based pharmacokinetic (PBPK) modelling tools: how to fit with our needs? Biopharm Drug Dispos 2012; 55-71.
-
(2012)
Biopharm Drug Dispos
, pp. 55-71
-
-
Bouzom, F.1
Ball, K.2
Perdaems, N.3
Walther, B.4
-
5
-
-
84862777396
-
Application of IVIVE and PBPK modeling in prospective prediction of clinical pharmacokinetics: Strategy and approach during the drug discovery phase with four case studies
-
Chen Y, Jin JY, Mukadam S, Malhi V, Kenny JR. Application of IVIVE and PBPK modeling in prospective prediction of clinical pharmacokinetics: strategy and approach during the drug discovery phase with four case studies. Biopharm Drug Dispos 2012; 85-98.
-
(2012)
Biopharm Drug Dispos
, pp. 85-98
-
-
Chen, Y.1
Jin, J.Y.2
Mukadam, S.3
Malhi, V.4
Kenny, J.R.5
-
6
-
-
84858704368
-
Using Simcyp to project human oral pharmacokinetic variability in early drug research to mitigate mechanism-based adverse events
-
Shaffer CL, Scialis RJ, Rong H, Obach RS. Using Simcyp to project human oral pharmacokinetic variability in early drug research to mitigate mechanism-based adverse events. Biopharm Drug Dispos 2012; 72-84.
-
(2012)
Biopharm Drug Dispos
, pp. 72-84
-
-
Shaffer, C.L.1
Scialis, R.J.2
Rong, H.3
Obach, R.S.4
-
7
-
-
84858660647
-
From preclinical to human - Prediction of oral absorption and drug-drug interaction potential using physiologically based pharmacokinetic (PBPK) modeling approach in industrial setting: A workflow by using case example
-
Sinha VK, Snoeys J, Van Osselaer N, Van Peer A, Mackie C, Heald D. From preclinical to human - prediction of oral absorption and drug-drug interaction potential using physiologically based pharmacokinetic (PBPK) modeling approach in industrial setting: a workflow by using case example. Biopharm Drug Dispos 2012; 111-121.
-
(2012)
Biopharm Drug Dispos
, pp. 111-121
-
-
Sinha, V.K.1
Snoeys, J.2
Van Osselaer, N.3
Van Peer, A.4
Mackie, C.5
Heald, D.6
-
8
-
-
84862777920
-
The role of physiologically based pharmacokinetic modeling in regulatory review
-
Huang SM, Rowland M. The role of physiologically based pharmacokinetic modeling in regulatory review. Clin Pharmacol Ther 2012; 91: 542-549.
-
(2012)
Clin Pharmacol Ther
, vol.91
, pp. 542-549
-
-
Huang, S.M.1
Rowland, M.2
-
9
-
-
84862776909
-
Utility of a physiologically-based pharmacokinetic (PBPK) modeling approach to quantitatively predict a complex drug-drug-disease interaction scenario with rivaroxaban during the drug review process: Implications for clinical practice
-
Grillo JA, Zhao P, Bullock J, et al. Utility of a physiologically-based pharmacokinetic (PBPK) modeling approach to quantitatively predict a complex drug-drug-disease interaction scenario with rivaroxaban during the drug review process: implications for clinical practice. Biopharm Drug Dispos 2012; 99-110.
-
(2012)
Biopharm Drug Dispos
, pp. 99-110
-
-
Grillo, J.A.1
Zhao, P.2
Bullock, J.3
|