Targeted delivery of oligonucleotides into tumor-associated macrophages for cancer immunotherapy

Journal of Controlled Release

Volumn 158, Issue 2, 2012, Pages 286-292

  Huang, Zhen ^a   Zhang, Zhengping ^a   Jiang, Yucui ^a   Zhang, Dachuan ^a   Chen, Jiangning ^a   Dong, Lei ^a   Zhang, Junfeng ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

Cancer immunotherapy; Nucleic acid drugs; Targeting delivery; Tumor associated macrophage

Indexed keywords

ACIDIC MICROENVIRONMENT; ANGIOGENESIS; ANTI-TUMOR ACTIVITIES; ANTITUMOR EFFECT; CANCER IMMUNOTHERAPY; DELIVERY SYSTEMS; DRIVING FORCES; INFLAMMATORY CYTOKINES; INHIBITORY EFFECT; INTRAVENOUS INJECTIONS; MURINE MODEL; NUCLEIC ACID DRUGS; TARGETED DELIVERY; TARGETING DELIVERY; THERAPEUTIC STRATEGY; TUMOR GROWTH; TUMOR IMMUNOTHERAPY; TUMOR MICROENVIRONMENT; UP-REGULATION;

BIOMOLECULES; DISEASES; MACROPHAGES; NUCLEIC ACIDS; OLIGONUCLEOTIDES;

TUMORS;

ANTI INTERLEUKIN 10 OLIGODEOXYNUCLEOTIDE; ANTI INTERLEUKIN 10 RECEPTOR OLIGODEOXYNUCLEOTIDE; ANTINEOPLASTIC AGENT; CPG OLIGODEOXYNUCLEOTIDE; GELATINASE B; INTERLEUKIN 10; INTERLEUKIN 10 ANTIBODY; INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; OLIGODEOXYNUCLEOTIDE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULOTROPIN;

ALLOGRAFT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOACCUMULATION; CANCER IMMUNOTHERAPY; CONTROLLED STUDY; DRUG EFFICACY; DRUG RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLUORESCENCE MICROSCOPY; GENE DELIVERY SYSTEM; GENETIC TRANSFECTION; IMMUNOREGULATION; IN VITRO STUDY; LIVER CANCER; LIVER CELL CARCINOMA; MOUSE; NONHUMAN; OLIGONUCLEOTIDE THERAPY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REAL TIME POLYMERASE CHAIN REACTION; TARGET CELL DESTRUCTION; TH1 CELL; TUMOR ASSOCIATED LEUKOCYTE; TUMOR MICROENVIRONMENT; UPREGULATION;

ALGINATES; ANIMALS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; DEXTRANS; HISTIDINE; IMMUNOTHERAPY; INTERLEUKIN-10; LIVER NEOPLASMS; MACROPHAGES; MICE; OLIGONUCLEOTIDES; POLYETHYLENE GLYCOLS; RECEPTORS, INTERLEUKIN-10; TRANSFECTION;

EID: 84858697942     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.11.013     Document Type: Article

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