Resectable pancreatic cancer: Is surgery the best first step?

Journal of the Pancreas

Volumn 13, Issue 2, 2012, Pages 151-154

  Russo, Suzanne ^a   Chabot, John ^b   Saif, Muhammad Wasif ^b  

^a UNIVERSITY OF SOUTH ALABAMA   (United States)

^b Department of Medicine   (United States)

Author keywords

Laparoscopy; Neoadjuvant therapy; Pancreatic neoplasms; Proteomics

Indexed keywords

ANTINEOPLASTIC AGENT; CA 19-9 ANTIGEN; TUMOR MARKER;

ADJUVANT CHEMORADIOTHERAPY; ADJUVANT THERAPY; ARTICLE; CANCER STAGING; CANCER SURVIVAL; CLINICAL EFFECTIVENESS; COMPUTER ASSISTED TOMOGRAPHY; COST BENEFIT ANALYSIS; COST EFFECTIVENESS ANALYSIS; CYTOLOGY; DIAGNOSTIC ACCURACY; DISEASE FREE SURVIVAL; HIGH RISK PATIENT; HUMAN; LAPAROSCOPY; METASTASIS POTENTIAL; OVERALL SURVIVAL; PANCREAS ADENOCARCINOMA; PANCREAS SURGERY; POSTOPERATIVE CARE; PRACTICE GUIDELINE; PREOPERATIVE CARE; PREOPERATIVE RADIOTHERAPY; PROGNOSIS; PROSPECTIVE STUDY; QUALITY ADJUSTED LIFE YEAR; RETROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; SURVIVAL TIME; TREATMENT RESPONSE;

ADENOCARCINOMA; CHEMORADIOTHERAPY, ADJUVANT; HUMANS; PANCREATIC NEOPLASMS;

EID: 84858690652     PISSN: 15908577     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Evans, D.B., T.A. Rich, D.R. Byrd, et al. Preoperative chemoradiation and pancreaticoduodenectomy for adenocarcinoma of the pancreas. Arch Surg, 1992. 127(11): 1335-1339.
2. Evans, D.B., G.R. Varadhachary, C.H. Crane, et al. Preoperative gemcitabine-based chemoradiation for patients with resectable adenocarcinoma of the pancreatic head. J Clin Oncol, 2008. 26(21): 3496-3502.
3. Varadhachary, G.R., R.A. Wolff, C.H. Crane, et al. Preoperative gemcitabine and cisplatin followed by gemcitabine-based chemoradiation for resectable adenocarcinoma of the pancreatic head. J Clin Oncol, 2008. 26(21): 3487-3495.
4. Gillen, S., T. Schuster, C. Meyer Zum Buschenfelde, et al. Preoperative/neoadjuvant therapy in pancreatic cancer: a systematic review and meta-analysis of response and resection percentages. PLoS Med, 2010. 7(4): e1000267.
5. Hohenberger W. Gemcitabine, Cisplatin, and Radiation Therapy Followed By Surgery or Surgery Alone in Treating Patients With Localized Pancreatic Cancer That Can Be Removed By Surgery. In: National Cancer Institute, ClinicalTrials.gov: NCT00335543.
6. Abbott DE, Tzeng C-W D, Merkow RP, Cantor SB, Katz MHG, Bentrem DJ, Bilimoria KY, Crane CH, Varadhachary GR, Fleming JB. Neoadjuvant chemoradiation versus surgery first for resectable pancreatic head adenocarcinoma: An economic and outcome analysis. J Clin Oncol 30, 2012 (suppl 4; abstr 156)
7. Santoro PM, Abdel-Misih RZ, Petrelli NJ, Bennett JJ. Is laparoscopy still needed for staging resectable pancreatic cancer? J Clin Oncol 30, 2012 (suppl 4; abstr 168)
8. Chen KT, Singla S, Papavasiliou P, Devarajan K, Hoffman JP. Revisiting the prognostic significance of positive peritoneal cytology in pancreatic cancer. J Clin Oncol 30, 2012 (suppl 4; abstr 177)
9. Brand R, Buchholz M, Mehan M, Whitcomb DC, Zeh H, Moser AJ, Gress TM, Williams S, dela Cruz M, Ostroff R. Detection of resectable pancreatic cancer with SOMAmer proteomic technology. J Clin Oncol 30, 2012 (suppl 4; abstr 162)
10. Klinkenbijl JH, Jeekel J, Sahmoud T, et al. Adjuvant radiotherapy and 5-fluorouracil after curative resection of cancer of the pancreas and periampullary region: phase III trial of the EORTC gastrointestinal tract cancer cooperative group. Ann Surg 1999. 230: 776-82; discussion 782-4.
11. Cheng TY, Sheth K, White RR et al. Effect of neoadjuvant chemoradiation on operative mortality and morbidity for pancreaticoduodenectomy. Ann Surg Oncol 2006. 13: 66-74.