Bone density in post-pubertal adolescent survivors of childhood brain tumors

Pediatric Blood and Cancer

Volumn 58, Issue 6, 2012, Pages 959-963

  Cohen, Laurie E ^a   Gordon, Joshua H ^a   Popovsky, Erica Y ^a   Sainath, Nina N ^b   Feldman, Henry A ^a   Kieran, Mark W ^a   Gordon, Catherine M ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Bone mineral density; Brain tumors; Fracture; Growth hormone deficiency

Indexed keywords

ANTINEOPLASTIC AGENT; HYPOPHYSIS HORMONE; RECOMBINANT GROWTH HORMONE;

ARTICLE; ASTROCYTOMA; BONE DENSITY; BONE MASS; BRAIN RADIATION; BRAIN TUMOR; CANCER CHEMOTHERAPY; CANCER DIAGNOSIS; CANCER RADIOTHERAPY; CANCER SURGERY; CANCER SURVIVOR; CHILD; CHILDHOOD CANCER; CLINICAL ARTICLE; CRANIOPHARYNGIOMA; DUAL ENERGY X RAY ABSORPTIOMETRY; EPENDYMOMA; FEMALE; FEMUR NECK FRACTURE; GERM CELL TUMOR; GLIOMA; GROWTH HORMONE DEFICIENCY; HIP FRACTURE; HUMAN; HYPOGONADISM; MALE; MEDULLOBLASTOMA; MENARCHE; PINEOBLASTOMA; PRIORITY JOURNAL; RISK FACTOR; SCHOOL CHILD; SCORING SYSTEM; SPINE FRACTURE;

ABSORPTIOMETRY, PHOTON; ADOLESCENT; AGE OF ONSET; BONE DENSITY; BRAIN NEOPLASMS; CHEMORADIOTHERAPY; CHILD; CRANIAL IRRADIATION; FEMALE; FRACTURES, BONE; HUMAN GROWTH HORMONE; HUMANS; HYPOGONADISM; MALE; PUBERTY; RADIOTHERAPY; RETROSPECTIVE STUDIES; RISK FACTORS; SURVIVORS;

EID: 84858690199     PISSN: 15455009     EISSN: 15455017     Source Type: Journal    
DOI: 10.1002/pbc.23300     Document Type: Article

References (40)

1. Vassilopoulou-Sellin R, Brosnan P, Delpassand A, et al. Osteopenia in young adult survivors of childhood cancer. Med Pediatr Oncol 1999; 32: 272-278.
2. Aisenberg J, Hsieh K, Kalaitzoglou G, et al. Bone mineral density in young adult survivors of childhood cancer. J Pediatr Hematol Oncol 1998; 20: 241-245.
3. Tillman V, Darlington ASE, Eiser C, et al. Male sex and low physical activity are associated with reduced spine bone mineral density in survivors of childhood lymphoblastic leukemia. J Bone Miner Res 2002; 17: 1073-1080.
4. Halton JM, Atkinson SA, Fraher L, et al. Mineral homeostasis and bone mass at diagnosis in children with acute lymphoblastic leukemia. J Pediatr 1995; 126: 557-564.
5. Arikoski P, Komulainen J, Riikonen P, et al. Alterations in bone turnover and impaired development of bone mineral density in newly diagnosed children with cancer: A 1-year prospective study. J Clin Endocrinol Metab 1999; 84: 3174-3181.
6. Barr RD, Simpson T, Webber CE, et al. Osteopenia in children surviving brain tumours. Eur J Cancer 1998; 34: 873-877.
7. Petraroli M, D'Alessio E, Ausili E, et al. Bone mineral density in survivors of childhood brain tumours. Childs Nerv Syst 2007; 23: 59-65.
8. Gurney JG, Kadan-Lottick NS, Packer RJ, et al. Endocrine and cardiovascular late effects among adult survivors of childhood brain tumors: Childhood cancer survivor study. Cancer 2003; 97: 663-673.
9. Olney RC. Regulation of bone mass by growth hormone. Med Pediatr Oncol 2003; 41: 228-234.
10. Sklar CA, Constine LS. Chronic neuroendocrinological sequelae of radiation therapy. Int J Radiat Oncol Biol Phys 1995; 31: 1113-1121.
11. Frank GR. Role of estrogen and androgen in pubertal skeletal physiology. Med Pediatr Oncol 2003; 41: 217-221.
12. Layman LC. Hypogonadotropic hypogonadism. Endocrinol Metab Clin North Am 2007; 36: 283-296.
13. Hopewell JW. Radiation-therapy effects on bone density. Med Pediatr Oncol 2003; 41: 208-211.
14. Krishnamoorthy P, Freeman C, Bernstein ML, et al. Osteopenia in children who have undergone posterior fossa or craniospinal irradiation for brain tumors. Arch Pediatr Adolesc Med 2004; 158: 491-496.
15. Hochberg Z. Mechanisms of steroid impairment of growth. Horm Res 2002; 58: 33-38.
16. Rehman Q, Lane NE. Effect of glucocorticoids on bone density. Med Pediatr Oncol 2003; 41: 212-216.
17. Muller J. Impact of cancer therapy on the reproductive axis. Horm Res 2003; 59: 12-20.
18. French SA, Fulkerson JA, Story M. Increasing weight-bearing physical activity and calcium intake for bone mass growth in children and adolescents: A review of intervention trials. Prev Med 2000; 31: 722-731.
19. Harz KJ, Muller HL, Waldeck E, et al. Obesity in patients with craniopharyngioma: Assessment of food intake and movement counts indicating physical activity. J Clin Endocrinol Metab 2003; 88: 5227-5231.
20. Dekkers OM, Biermasz NR, Smit JW, et al. Quality of life in treated adult craniopharyngioma patients. Eur J Endocrinol 2006; 154: 483-489.
21. Brabant G, Wallaschofski H. Normal levels of serum IGF-I: Determinants and validity of current reference ranges. Pituitary 2007; 10: 129-133.
22. Matkovic V, Landoll JD, Badenhop-Stevens NE, et al. Nutrition influences skeletal development from childhood to adulthood: A study of hip, spine, and forearm in adolescent females. J Nutr 2004; 134: 701S-705S.
23. Henderson RC, Madsen CD, Davis C, et al. Bone density in survivors of childhood malignancies. J Pediatr Hematol Oncol 1996; 18: 367-371.
24. Odame I, Duckworth J, Talsma D, et al. Osteopenia, physical activity and health-related quality of life in survivors of brain tumors treated in childhood. Pediatr Blood Cancer 2006; 46: 357-362.
25. Pietila S, Sievanen H, Ala-Houhala M, et al. Bone mineral density is reduced in brain tumour patients treated in childhood. Acta Paediatr 2006; 95: 1291-1297.
26. Kalkwarf HJ, Zemel BS, Gilsanz V, et al. The bone mineral density in childhood study: Bone mineral content and density according to age, sex, and race. J Clin Endocrinol Metab 2007; 92: 2087-2099.
27. Katzman DK, Bachrach LK, Carter DR, et al. Clinical and anthropometric correlates of bone mineral acquisition in healthy adolescent girls. J Clin Endocrinol Metab 1991; 73: 1332-1339.
28. Bhudhikanok GS, Wang MC, Eckert K, et al. Differences in bone mineral in young Asian and Caucasian Americans may reflect differences in bone size. J Bone Miner Res 1996; 11: 1545-1556.
29. Theintz G, Buchs B, Rizzoli R, et al. Longitudinal monitoring of bone mass accumulation in healthy adolescents: Evidence for a marked reduction after 16 years of age at the levels of lumbar spine and femoral neck in female subjects. J Clin Endocrinol Metab 1992; 75: 1060-1065.
30. Jones IE, Taylor RW, Williams SM, et al. Four-year gain in bone mineral in girls with and without past forearm fractures: A DXA study. Dual energy X-ray absorptiometry. J Bone Miner Res 2002; 17: 1065-1072.
31. Giustina A, Mazziotti G, Canalis E. Growth hormone, insulin-like growth factors, and the skeleton. Endocr Rev 2008; 29: 535-559.
32. Radovick S, DiVall S. Approach to the growth hormone-deficient child during transition to adulthood. J Clin Endocrinol Metab 2007; 92: 1195-1200.
33. Soyka LA, Fairfield WP, Klibanski A. Clinical review 117: Hormonal determinants and disorders of peak bone mass in children. J Clin Endocrinol Metab 2000; 85: 3951-3963.
34. Hogler W, Shaw N. Childhood growth hormone deficiency, bone density, structures and fractures: Scrutinizing the evidence. Clin Endocrinol (Oxf) 2010; 72: 281-289.
35. Mauras N, Pescovitz OH, Allada V, et al. Limited efficacy of growth hormone (GH) during transition of GH-deficient patients from adolescence to adulthood: A phase III multicenter, double-blind, randomized two-year trial. J Clin Endocrinol Metab 2005; 90: 3946-3955.
36. Conway GS, Szarras-Czapnik M, Racz K, et al. Treatment for 24 months with recombinant human GH has a beneficial effect on bone mineral density in young adults with childhood-onset GH deficiency. Eur J Endocrinol 2009; 160: 899-907.
37. Bassett JH, Williams GR. Critical role of the hypothalamic-pituitary-thyroid axis in bone. Bone 2008; 43: 418-426.
38. Leonard MB. Assessment of bone health in children and adolescents with cancer: Promises and pitfalls of current techniques. Med Pediatr Oncol 2003; 41: 198-207.
39. Kaste SC. Bone-mineral density deficits from childhood cancer and its therapy. A review of at-risk patient cohorts and available imaging methods. Pediatr Radiol 2004; 34: 373-378, quiz 443-444.
40. Arikoski P, Voutilainen R, Kroger H. Bone mineral density in long-term survivors of childhood cancer. J Pediatr Endocrinol Metab 2003; 16: 343-353.