Escherichia coli from Italy producing OXA-48 carbapenemase encoded by a novel Tn1999 transposon derivative

Antimicrobial Agents and Chemotherapy

Volumn 56, Issue 4, 2012, Pages 2211-2213

  Giani, Tommaso ^a   Conte, Viola ^a   Di Pilato, Vincenzo ^a   Aschbacher, Richard ^b   Weber, Cordula ^c   Larcher, Clara ^b   Rossolini, Gian Maria ^a  

^a UNIVERSITY OF SIENA   (Italy)

^b CENTRAL HOSPITAL OF BOLZANO   (Italy)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; AMOXICILLIN PLUS CLAVULANIC ACID; AMPICILLIN; CARBAPENEMASE; CEFEPIME; CEFOTAXIME; CEFTAZIDIME; CIPROFLOXACIN; COLISTIN; ERTAPENEM; GENTAMICIN; IMIPENEM; LEVOFLOXACIN; MEROPENEM; NALIDIXIC ACID; OXA 48 CARBAPENEMASE; PIPERACILLIN PLUS TAZOBACTAM; RIFAMPICIN; SULFAMETHOXAZOLE; TIGECYCLINE; TOBRAMYCIN; TRIMETHOPRIM; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM ISOLATION; DRUG CONJUGATION; ESCHERICHIA COLI; GENE MAPPING; GENETIC CODE; ITALY; KLEBSIELLA PNEUMONIAE; LETTER; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; TRANSPOSON;

ANTI-BACTERIAL AGENTS; BETA-LACTAMASES; CHROMOSOME MAPPING; DNA TRANSPOSABLE ELEMENTS; ESCHERICHIA COLI; FEMALE; HUMANS; ITALY; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; MOLECULAR SEQUENCE DATA; PLASMIDS; URINARY TRACT INFECTIONS;

EID: 84858668776     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00035-12     Document Type: Letter

References (17)

1. Carrer A, et al. 2008. Spread of OXA-48-positive carbapenem-resistant Klebsiella pneumoniae isolates in Istanbul, Turkey. Antimicrob. Agents Chemother. 52:2950-2954.
2. Clermont O, Bonacorsi S, Bingen E. 2000. Rapid and simple determination of the Escherichia coli phylogenetic group. Appl. Environ. Microbiol. 66:4555-4558.
3. D'Andrea MM, et al. 2009. Characterization of pABVA01, a plasmid encoding the OXA-24 carbapenemase from Italian isolates of Acinetobacter baumannii. Antimicrob. Agents Chemother. 53:3528-3533.
4. D'Andrea MM, et al. 2011. Persistent carriage and infection by multidrug-resistant Escherichia coli ST405 producing NDM-1 carbapenemase: report on the first Italian cases. J. Clin. Microbiol. 49:2755-2758.
5. Docquier JD, et al. 2009. Crystal structure of the OXA-48 β-lactamase reveals mechanistic diversity among class D carbapenemases. Chem. Biol. 16:540-547.
6. Giani T, et al. 2009. Emergence in Italy of Klebsiella pneumoniae sequence type 258 producing KPC-3 carbapenemase. J. Clin. Microbiol. 47:3793-3794.
7. Goren MG, Navon-Venezia S, Chmelnitsky I, Carmeli Y. 2010. Carbapenem-resistant KPC-2-producing Escherichia coli in a Tel Aviv medical center, 2005 to 2008. Antimicrob. Agents Chemother. 54:2687-2691.
8. VIM, a new integron-borne metallo-β-lactamase gene from a Pseudomonas aeruginosa clinical isolate. Antimicrob. Agents Chemother. 43:1584-1590.
9. Lee K, et al. 2001. Modified Hodge and EDTA-disc synergy tests to screen metallo-β-lactamase-producing strains of Pseudomonas and Acinetobacter species. Clin. Microbiol. Infect. 7:88-91. (Pubitemid 34960278)
10. Nordmann P, Naas T, Poirel L. 2011. Global spread of carbapenemase- producing Enterobacteriaceae. Emerging Infect. Dis. 17:1791-1798.
11. Pallecchi L, et al. 2004. Detection of CTX-M-type β-lactamase genes in fecal Escherichia coli isolates from healthy children in Bolivia and Peru. Antimicrob. Agents Chemother. 48:4556-4561. (Pubitemid 39577653)
12. Perilli M, et al. 2002. Molecular characterization of extended-spectrum β-lactamases produced by nosocomial isolates of Enterobacteriaceae from an Italian nationwide survey. J. Clin. Microbiol. 40:611-614. (Pubitemid 34130889)
13. Poirel L, Bonnin RA, Nordmann P. 2011. Genetic features of the widespread plasmid coding for the carbapenemase OXA-48. Antimicrob. Agents Chemother. 2012. 56:559-562.
14. Poirel L, Héritier C, Tolün V, Nordmann P. 2004. Emergence of oxacillinase-mediated resistance to imipenem in Klebsiella pneumoniae. Antimicrob. Agents Chemother. 48:15-22. (Pubitemid 38040171)
15. Sambrook J, Fritsch EF, Maniatis T. 1989. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
16. Tsakris A, et al. 2009. Use of boronic acid disk tests to detect extended-spectrum β-lactamases in clinical isolates of KPC carbapenemase-possessing Enterobacteriaceae. J. Clin. Microbiol. 47:3420-3426.
17. Wolfson JS, Hooper DC, Swartz MN, Swartz MD, McHugh GL. 1983. Rapid method for screening large numbers of Escherichia coli colonies for production of plasmid-mediated β-lactamases. Antimicrob. Agents Chemother. 23:308-312. (Pubitemid 13137543)