Performance assessment using mixed effects models: A case study on coronary patient care

IMA Journal of Management Mathematics

Volumn 23, Issue 2, 2012, Pages 117-131

  Grieco, Niccolò ^a   Ieva, Francesca ^b   Paganoni, Anna Maria ^b  

^a OSPEDALE NIGUARDA CA GRANDA   (Italy)

^b POLITECNICO DI MILANO   (Italy)

Author keywords

generalized linear mixed models; in hospital survival; provider profiling; ST elevation myocardial infarction

Indexed keywords

C (PROGRAMMING LANGUAGE); DIAGNOSIS; HOSPITALS; SURVEYS;

GENERALIZED LINEAR MIXED MODELS; GENERALIZED LINEAR MIXED-EFFECTS MODELS; IN-HOSPITAL SURVIVAL; MEDICAL PRACTITIONER; MIXED EFFECTS MODELS; MYOCARDIAL INFARCTION; NON-PARAMETRIC; PATIENT CARE; PERFORMANCE ASSESSMENT; PROCESS INDICATORS; PROVIDER PROFILING; RANDOM EFFECTS; SURVEY DATA; SURVIVAL RATE; THREE DIFFERENT TECHNIQUES;

QUALITY CONTROL;

EID: 84858668606     PISSN: 1471678X     EISSN: 14716798     Source Type: Journal    
DOI: 10.1093/imaman/dpr007     Document Type: Article

References (25)

1. AITKIN M. (1999) A general maximum likelihood analysis of variance components in generalized linear models. Biometrics, 55, 117-128.
2. ANTMAN E. M., HAND M., AMSTRONG P. W., BATES E. R. & GREEN L. A. (2008) Update of the ACC/AHA 2004 guidelines for the management of patients with ST elevation myocardial infarction. Circulation, 117, 269-329.
3. BARBIERI P., GRIECO N., IEVA F., PAGANONI A.M. & SECCHI P. (2010) Exploitation, integration and statistical analysis of Public Health Database and STEMI archive in Lombardia Region. Complex Data Modeling and Computationally Intensive Statistical Methods. Springer: Contribution to Statistics.
4. BATES D. & MAECHLER M. (2010) lme4: Linear mixed-effects models using S4 classes. Available at http://CRAN.R-project.org/package=lme4.
5. CANNON C. P., GIBSON C. M., LAMBREW C. T., SHOULTZ D. A., LEVY D., FRENCH W. J., GORE J. M., WEAVER W. D., ROGERS W. J. & TIEFENBRUNN A. J. (2000) Relationship of symptomonset- to-balloon time and door-to-balloon time with mortality in patients undergoing angioplasty for acute myocardial infarction. J. Am. Med. Assoc., 283, 2941-2947.
6. DALBY M., BOUZAMONDO A., LECHAT P. & MONTALESCOT G. (2003) Transfer for primary angioplasty versus immediate thrombolysis in AMI: A meta-analysis. Circulation, 108, 1809-1814.
7. EINBECK J., DARNELL R. & HINDE J. (2009) npmlreg: Nonparametric maximum likelihood estimation for random effect models [online]. Available at http://CRAN.R-project.org/package=npmlreg.
8. GOLDSTEIN H. (2003) Multilevel Statistical Models. London: Arnolds.
9. GRIECO N., CORRADA E., SESANA G., FONTANA G., LOMBARDI F., IEVA F., PAGANONI A. M. & MARZEGALLI M. (2008) Predictors of reduction of treatment time for ST-segment elevation myocardial infarction in a complex urban reality. The MOMI2 survey. Mox Report no. 10/2008, Dipartimento di Matematica, Politecnico di Milano, Milano. Available at http://mox.polimi.it/it/progetti/ pubblicazioni/quaderni/10- 2008.pdf.
10. GUGLIELMI A., IEVA F., PAGANONI A. M. & RUGGERI F. (2010) A Bayesian random-effects model for survival probabilities after acute myocardial infarction. Mox Report no. 17/2010. Dipartimento di Matematica, Politecnico di Milano, Milano. Available at http://mox.polimi.it/it/progetti/pubblicazioni/ quaderni/17- 2010.pdf.
11. HARTIGAN J. A. & WONG M. A. (1979) A k-means clustering algorithm. Appl. Stat., 28, 100-108.
12. HASDAY D., BEHAR S. & WALLENTIN L. (2002) A prospective survey of the characteristics, treatments and outcomes of patients with acute coronary syndromes in Europe and the Mediterranean basin. The euro heart survey of acute coronary syndromes (euro heart survey ACS). Eur. Heart J., 23, 1190-1210.
13. IEVA F. (2008) Modelli statistici per lo studio dei tempi di intervento nell'infarto miocardico acuto. Master Thesis, Dipartimento di Matematica, Politecnico di Milano. Available at http://mox.polimi.it/it/progetti/ pubblicazioni/tesi/ieva.pdf.
14. IEVA F. & PAGANONI A. M. (2009) A case study on treatment times in patients with ST-segment elevation myocardial infarction. Mox Report no. 05/2009. Dipartimento di Matematica, Politecnico di Milano, Milano. Available at http://mox.polimi.it/it/progetti/pubblicazioni/quaderni/05-2009.pdf.
15. IEVA F. & PAGANONI A. M. (2010) Multilevel models for clinical registers concerning STEMI patients in a complex urban reality: A statistical analysis of MOMI2 survey. Commun. Appl. Indust. Math., 1, 128-147.
16. LINDSAY B. G. (1983) The geometry of mixture likelihoods: A general theory. Ann. Stat., 11, 86-94.
17. MCCULLAGH P. & NELDER J. A. (2000) Generalized Linear Models. London: Chapman & Hall/CRC.
18. OLTRONA L., MAFRICI A., MARZEGALLI M., FIORENTINI C., PIROLA R. & VINCENTI A. (2005) La gestione della fase iperacuta dellinfarto miocardico con sopraslivellamento del tratto ST nella Regione Lombardia (GestIMA). Italian Heart J., 6, 489-497.
19. PINHEIRO C. & BATES D. M. (2000) Mixed-Effects Models in S and S-Plus. New York: Springer.
20. R DEVELOPMENT CORE TEAM (2009) R: A Language and Environment for Statistical Computing. Vienna, Austria: R Foundation for Statistical Computing. Available at http://www.R-project.org.
21. RACZ J. & SEDRANSK J. (2010) Bayesian and frequentist methods for provider profiling using risk-adjusted assessments of medical outcomes. J. Am. Stat. Assoc., 105, 48-58.
22. RATHORE S. S., CURTIS J. P. & CHEN U. J. (2009) Association of door to balloon time and mortality in patients admitted to hospital with ST-elevation myocardial infarction: National cohort study. Br. Med. J., 338, b1807.
23. SAIA F., MARZOCCHI A., MANARI G., GUASTAROBA P., VIGNALI L. & VARANI E. (2009) Patient selection to enhance the long-term benefit of first generation drug-eluting stents for coronary revascularization procedures: Insights from a large multicenter registry. Eurointervention, 5, 57-66.
24. STRUYF A., HUBERT M. & ROUSSEEUW P. J. (1996) Clustering in an object-oriented environment. J. Stat. Softw., 1.
25. TING H. H., KRUMHOLTZ H. M., BRADLEY E. H., CONE D. C. & CURTIS J. P. (2008) Implementation and integration of prehospital ECGs into system of care for acute coronary syndrome. Circulation, 118, 1066-1079.