Cell biological characterization of a multidomain adaptor protein, ArgBP2, in epithelial NMuMG cells, and identification of a novel short isoform

Medical Molecular Morphology

Volumn 45, Issue 1, 2012, Pages 22-28

  Murase, Kana ^a   Ito, Hidenori ^b   Kanoh, Hiroyuki ^a   Sudo, Kaori ^b   Iwamoto, Ikuko ^b   Morishita, Rika ^b   Soubeyran, Philippe ^c   Seishima, Mariko ^a   Nagata, Koh Ichi ^b  

^a GIFU UNIVERSITY   (Japan)

^b INSTITUTE FOR DEVELOPMENTAL RESEARCH   (Japan)

^c INSERM   (France)

Author keywords

Adaptor protein; ArgBP2; Cell polarity; NMuMG cells; Tight junction

Indexed keywords

ADAPTOR PROTEIN; ADAPTOR PROTEIN ARGBP2; ADAPTOR PROTEIN ARGBP2 DELTA; ISOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN ZO1; UNCLASSIFIED DRUG; VINEXIN BETA;

ANIMAL CELL; ARTICLE; CELL COMMUNICATION AND CELL CONTACT; CELL STRAIN; CELL STRAIN 3T3; CELL STRAIN NMUMG; CELL STRUCTURE; CYTOPLASM; ENZYME ACTIVATION; EPITHELIUM CELL; FIBROBLAST; GENE MUTATION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAIN; TIGHT JUNCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CACO-2 CELLS; CELL ADHESION; CELL LINE; CELL POLARITY; COS CELLS; CYTOPLASM; DNA MUTATIONAL ANALYSIS; EPITHELIAL CELLS; FIBROBLASTS; FLUORESCENT ANTIBODY TECHNIQUE; HELA CELLS; HOMEODOMAIN PROTEINS; HUMANS; MICE; MUSCLE PROTEINS; NIH 3T3 CELLS; PROTEIN ISOFORMS; RATS; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS; TIGHT JUNCTIONS;

EID: 84858638733     PISSN: 18601480     EISSN: 18601499     Source Type: Journal    
DOI: 10.1007/s00795-010-0537-9     Document Type: Article

References (27)

1. Kioka N, Ueda K, Amachi T (2002) Vinexin, CAP/ponsin, ArgBP2: a novel adaptor protein family regulating cytoskeletal organization and signal transduction. Cell Struct Funct 27:1-7 (Pubitemid 34498349)
2. Roignot J, Soubeyran P (2009) ArgBP2 and the SoHo family of adapter proteins in oncogenic diseases. Cell Adh Migr 3:167-170
3. Kimura A, Baumann CA, Chiang SH, Saltiel AR (2001) The sorbin homology domain: a motif for the targeting of proteins to lipid rafts. Proc Natl Acad Sci U S A 98:9098-9103 (Pubitemid 32743875)
4. Cestra G, Toomre D, Chang S, De Camilli P (2005) The Abl/Arg substrate ArgBP2/nArgBP2 coordinates the function of multiple regulatory mechanisms converging on the actin cytoskeleton. Proc Natl Acad Sci U S A 102:1731-1736 (Pubitemid 40209236)
5. Wang B, Golemis EA, Kruh GD (1997) ArgBP2, a multiple Src homology 3 domain-containing, Arg/Abl-interacting protein, is phosphorylated in v-Abl-transformed cells and localized in stress fibers and cardiocyte Z-disks. J Biol Chem 272:17542-17550 (Pubitemid 27311187)
6. Yuan ZQ, Kim D, Kaneko S, Sussman M, Bokoch GM, Kruh GD, Nicosia SV, Testa JR, Cheng JQ (2005) ArgBP2gamma interacts with Akt and p21-activated kinase-1 and promotes cell survival. J Biol Chem 280:21483-21490 (Pubitemid 40805713)
7. Kawabe H, Hata Y, Takeuchi M, Ide N, Mizoguchi A, Takai Y (1999) nArgBP2, a novel neural member of ponsin/ArgBP2/vinexin family that interacts with synapse-associated protein 90/postsynaptic density-95-associated protein (SAPAP). J Biol Chem 274:30914-30918
8. Soubeyran P, Barac A, Szymkiewicz I, Dikic I (2003) Cbl-ArgBP2 complex mediates ubiquitination and degradation of c-Abl. Biochem J 370:29-34 (Pubitemid 36259416)
9. Haglund K, Ivankovic-Dikic I, Shimokawa N, Kruh GD, Dikic I (2004) Recruitment of Pyk2 and Cbl to lipid rafts mediates signals important for actin reorganization in growing neurites. J Cell Sci 117:2557-2568 (Pubitemid 38877851)
10. Taieb D, Roignot J, Andre F, Garcia S, Masson B, Pierres A, Iovanna JL, Soubeyran P (2008) ArgBP2-dependent signaling regulates pancreatic cell migration, adhesion, and tumorigenicity. Cancer Res 68:4588-4596
11. Roignot J, Taieb D, Suliman M, Dusetti NJ, Iovanna JL, Soubeyran P (2010) CIP4 is a new ArgBP2 interacting protein that modulates the ArgBP2 mediated control of WAVE1 phosphorylation and cancer cell migration. Cancer Lett 288:116-123
12. Ito H, Iwamoto I, Mizutani K, Morishita R, Deguchi T, Nozawa Y, Asano T, Nagata K (2006) Possible interaction of a Rho effector, Rhotekin, with a PDZ-protein, PIST, at synapses of hippocampal neurons. Neurosci Res 56:165-171 (Pubitemid 44374789)
13. Mizutani K, Ito H, Iwamoto I, Morishita R, Deguchi T, Nozawa Y, Asano T, Nagata K (2007) Essential roles of ERK-mediated phosphorylation of vinexin in cell spreading, migration and anchorageindependent growth. Oncogene 26:7122-7131 (Pubitemid 350059675)
14. Miettinen PJ, Ebner R, Lopez AR, Derynck R (1994) TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: involvement of type I receptors. J Cell Biol 127:2021-2036
15. Ito H, Iwamoto I, Morishita R, Nozawa Y, Narumiya S, Asano T, Nagata K (2005) Possible role of Rho/Rhotekin signaling in mammalian septin organization. Oncogene 24:7064-7072 (Pubitemid 41573635)
16. Hanai N, Nagata K, Kawajiri A, Shiromizu T, Saitoh N, Hasegawa Y, Murakami S, Inagaki M (2004) Biochemical and cell biological characterization of a mammalian septin, Sept11. FEBS Lett 568:83-88 (Pubitemid 38757960)
17. Sudo K, Ito H, Iwamoto I, Morishita R, Asano T, Nagata K (2007) SEPT9 sequence alternations causing hereditary neuralgic amyotrophy are associated with altered interactions with SEPT4/SEPT11 and resistance to Rho/Rhotekin-signaling. Hum Mutat 28:1005-1013 (Pubitemid 47519393)
18. Nagata K, Kawajiri A, Matsui S, Takagishi M, Shiromizu T, Saitoh N, Izawa I, Kiyono T, Itoh TJ, Hotani H, Inagaki M (2003) Filament formation of MSF-A, a mammalian septin, in human mammary epithelial cells depends on interactions with microtubules. J Biol Chem 278:18538-18543 (Pubitemid 36799479)
19. Suwa A, Mitsushima M, Ito T, Akamatsu M, Ueda K, Amachi T, Kioka N (2002) Vinexin beta regulates the anchorage dependence of ERK2 activation stimulated by epidermal growth factor. J Biol Chem 277:13053-13058 (Pubitemid 34952674)
20. Nagata K, Ito H, Iwamoto I, Morishita R, Asano T (2009) Interaction of a multi-domain adaptor protein, vinexin, with a Rho-effector, Rhotekin. Med Mol Morphol 42:9-15
21. Akamatsu M, Aota S, Suwa A, Ueda K, Amachi T, Yamada KM, Akiyama SK, Kioka N (1999) Vinexin forms a signaling complex with Sos and modulates epidermal growth factor-induced c-Jun N-terminal kinase/stress-activated protein kinase activities. J Biol Chem 274:35933-35937 (Pubitemid 129512901)
22. Mitsushima M, Sezaki T, Akahane R, Ueda K, Suetsugu S, Takenawa T, Kioka N (2006) Protein kinase A-dependent increase in WAVE2 expression induced by the focal adhesion protein vinexin. Genes Cells 11:281-292
23. Kioka N, Sakata S, Kawauchi T, Amachi T, Akiyama SK, Okazaki K, Yaen C, Yamada KM, Aota S (1999) Vinexin: a novel vinculinbinding protein with multiple SH3 domains enhances actin cytoskeletal organization. J Cell Biol 144:59-69
24. Mitsushima M, Suwa A, Amachi T, Ueda K, Kioka N (2004) Extracellular signal-regulated kinase activated by epidermal growth factor and cell adhesion interacts with and phosphorylates vinexin. J Biol Chem 279:34570-34577 (Pubitemid 39318086)
25. Matsuyama M, Mizusaki H, Shimono A, Mukai T, Okumura K, Abe K, Shimada K, Morohashi K (2005) A novel isoform of vinexin, vinexin gamma, regulates Sox9 gene expression through activation of MAPK cascade in mouse fetal gonad. Genes Cells 10:421-434 (Pubitemid 40590360)
26. Kioka N, Ito T, Yamashita H, Uekawa N, Umemoto T, Motoyoshi S, Imai H, Takahashi K, Watanabe H, Yamada M, Ueda K (2010) Crucial role of vinexin for keratinocyte migration in vitro and epidermal wound healing in vivo. Exp Cell Res 316:1728-1738
27. Ronty M, Taivainen A, Moza M, Kruh GD, Ehler E, Carpen O (2005) Involvement of palladin and alpha-actinin in targeting of the Abl/Arg kinase adaptor ArgBP2 to the actin cytoskeleton. Exp Cell Res 310:88-98 (Pubitemid 41393690)