The effect of budesonide/formoterol pressurized metered-dose inhaler on predefined criteria for worsening asthma in four different patient populations with asthma

Drugs in R and D

Volumn 12, Issue 1, 2012, Pages 9-14

  Murphy, Kevin R ^a   Uryniak, Tom ^b   Martin, Ubaldo J ^b   Zangrilli, James ^b  

^a BOYS TOWN NATIONAL RESEARCH HOSPITAL   (United States)

^b ASTRAZENECA   (United Kingdom)

Author keywords

Asthma; Budesonide; Budesonide formoterol

Indexed keywords

BRONCHODILATING AGENT; BUDESONIDE PLUS FORMOTEROL; CORTICOSTEROID;

ADULT; AROUSAL; ARTICLE; ASTHMA; CONTROLLED STUDY; DISEASE EXACERBATION; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRY POWDER; FEMALE; FORCED EXPIRATORY VOLUME; HISPANIC; HUMAN; LUNG FUNCTION; MAJOR CLINICAL STUDY; MALE; METERED DOSE INHALER; NIGHT; PEAK EXPIRATORY FLOW; POPULATION; PRIORITY JOURNAL; RACE; RANDOMIZED CONTROLLED TRIAL; SELF REPORT;

ADMINISTRATION, INHALATION; ADULT; ANTI-ASTHMATIC AGENTS; ASTHMA; BUDESONIDE; DOUBLE-BLIND METHOD; DRUG COMBINATIONS; ETHANOLAMINES; FEMALE; HUMANS; MALE; METERED DOSE INHALERS; MIDDLE AGED; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME;

EID: 84858632448     PISSN: 11745886     EISSN: 11796901     Source Type: Journal    
DOI: 10.2165/11630600-000000000-00000     Document Type: Article

References (9)

1. American Lung Association. Trends in asthma morbidity and mortality. July 2011 [online]. Available from URL: http:// www.lungusa.org/finding-cures/our- research/trend-reports/ asthma-trend-report.pdf [Accessed 2011 Oct 21]
2. Reddel HK, Taylor DR, Bateman ED, et al. An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations. Am J Respir Crit Care Med 2009; 180 (1): 59-99
3. Nathan RA,Nolte H, Pearlman DS, P04334 Study Investigators. Twenty-six-week efficacy and safety study of mometasone furoate/formoterol 200/10 mg combination treatment in patients with persistent asthma previously receiving medium-dose inhaled corticosteroids. Allergy Asthma Proc 2010; 31 (4): 269-79
4. Kavuru M, Melamed J, Gross G, et al. Salmeterol and fluticasone propionate combined in a new powder inhalation device for the treatment of asthma: a randomized, doubleblind, placebo-controlled trial. J Allergy Clin Immunol 2000; 105 (6 Pt 1): 1108-16 (Pubitemid 30418788)
5. Noonan M, Rosenwasser LJ, Martin P, et al. Efficacy and safety of budesonide and formoterol in one pressurized metered-dose inhaler in adults and adolescents with moderate to severe asthma: a randomised clinical trial. Drugs 2006; 66 (5): 2235-54 (Pubitemid 44878530)
6. Corren J, Korenblat PE, Miller CJ, et al. Twelve-week, randomized, placebo-controlled, multicenter study of the efficacy and tolerability of budesonide and formoterol in one metered-dose inhaler compared with budesonide alone and formoterol alone in adolescents and adults with asthma. Clin Ther 2007 May; 29 (5): 823-43 (Pubitemid 47225183)
7. Spector SL, Martin UJ, Uryniak T, et al. Budesonide/ formoterol pressurized metered dose inhaler versus budesonide: a randomized controlled trial in Black patients with asthma. J Asthma 2012; 49 (1): 70-7
8. Zangrilli J, Mansfield LE, Uryniak T, et al. Efficacy of budesonide/formoterol pressurized metered-dose inhaler versus budesonide pressurized metered-dose inhaler alone in Hispanic adults and adolescents with asthma: a randomized, controlled trial. Ann Allergy Asthma Immunol 2011; 107 (3): 258-65
9. Bailey W, Castro M, Matz J, et al. Asthma exacerbations in African Americans treated for 1 year with combination fluticasone propionate and salmeterol or fluticasone propionate alone. Curr Med Res Opin 2008; 24 (6): 1669-82 (Pubitemid 351929065)