메뉴 건너뛰기




Volumn 12, Issue , 2012, Pages

A designer hyper interleukin 11 (H11) is a biologically active cytokine

Author keywords

Fusion protein; Gp130 targeting; Hyper IL11; Hypercytokine; IL 11; Sil 11R

Indexed keywords

FUSION PROTEINS; GP130 TARGETING; HYPER-IL11; HYPERCYTOKINE; IL-11;

EID: 84858592134     PISSN: None     EISSN: 14726750     Source Type: Journal    
DOI: 10.1186/1472-6750-12-8     Document Type: Article
Times cited : (32)

References (31)
  • 1
    • 0030917254 scopus 로고    scopus 로고
    • Interleukin-11: review of molecular, cell biology, and clinical use
    • Du X, Williams DA. Interleukin-11: review of molecular, cell biology, and clinical use. Blood 1997, 89(11):3897-3908.
    • (1997) Blood , vol.89 , Issue.11 , pp. 3897-3908
    • Du, X.1    Williams, D.A.2
  • 3
    • 0035697523 scopus 로고    scopus 로고
    • IL-11 is a potent anti-melanoma factor
    • 10.1007/978-1-4615-0685-0_54, 11774596
    • Dams-Kozlowska H, Izycki D, Mackiewicz A. IL-11 is a potent anti-melanoma factor. Adv Exp Med Biol 2001, 495:373-377. 10.1007/978-1-4615-0685-0_54, 11774596.
    • (2001) Adv Exp Med Biol , vol.495 , pp. 373-377
    • Dams-Kozlowska, H.1    Izycki, D.2    Mackiewicz, A.3
  • 4
    • 52949126357 scopus 로고    scopus 로고
    • Conditional gp130 deficient mouse mutants
    • 10.1016/j.semcdb.2008.07.001, 18687405
    • Fasnacht N, Muller W. Conditional gp130 deficient mouse mutants. Semin Cell Dev Biol 2008, 19(4):379-384. 10.1016/j.semcdb.2008.07.001, 18687405.
    • (2008) Semin Cell Dev Biol , vol.19 , Issue.4 , pp. 379-384
    • Fasnacht, N.1    Muller, W.2
  • 5
    • 80052358980 scopus 로고    scopus 로고
    • Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling
    • 10.1172/JCI57158, 3163962, 21881215
    • Jones SA, Scheller J, Rose-John S. Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling. J Clin Invest 2011, 121(9):3375-3383. 10.1172/JCI57158, 3163962, 21881215.
    • (2011) J Clin Invest , vol.121 , Issue.9 , pp. 3375-3383
    • Jones, S.A.1    Scheller, J.2    Rose-John, S.3
  • 6
    • 77956529798 scopus 로고    scopus 로고
    • GP130 cytokines and bone remodelling in health and disease
    • 10.5483/BMBRep.2010.43.8.513, 20797312
    • Sims NA, Walsh NC. GP130 cytokines and bone remodelling in health and disease. BMB Rep 2010, 43(8):513-523. 10.5483/BMBRep.2010.43.8.513, 20797312.
    • (2010) BMB Rep , vol.43 , Issue.8 , pp. 513-523
    • Sims, N.A.1    Walsh, N.C.2
  • 7
    • 0041677606 scopus 로고    scopus 로고
    • Principles of interleukin (IL)-6-type cytokine signalling and its regulation
    • 1223585, 12773095
    • Heinrich PC, Behrmann I, Haan S, Hermanns HM, Muller-Newen G, Schaper F. Principles of interleukin (IL)-6-type cytokine signalling and its regulation. Biochem J 2003, 374(Pt 1):1-20. 1223585, 12773095.
    • (2003) Biochem J , vol.374 , Issue.PART 1 , pp. 1-20
    • Heinrich, P.C.1    Behrmann, I.2    Haan, S.3    Hermanns, H.M.4    Muller-Newen, G.5    Schaper, F.6
  • 8
    • 0034680833 scopus 로고    scopus 로고
    • Interleukin-11 signals through the formation of a hexameric receptor complex
    • 10.1074/jbc.M004648200, 10948192
    • Barton VA, Hall MA, Hudson KR, Heath JK. Interleukin-11 signals through the formation of a hexameric receptor complex. J Biol Chem 2000, 275(46):36197-36203. 10.1074/jbc.M004648200, 10948192.
    • (2000) J Biol Chem , vol.275 , Issue.46 , pp. 36197-36203
    • Barton, V.A.1    Hall, M.A.2    Hudson, K.R.3    Heath, J.K.4
  • 9
    • 0032168152 scopus 로고    scopus 로고
    • Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway
    • 1219691, 9716487
    • Heinrich PC, Behrmann I, Muller-Newen G, Schaper F, Graeve L. Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway. Biochem J 1998, 334(Pt 2):297-314. 1219691, 9716487.
    • (1998) Biochem J , vol.334 , Issue.PART 2 , pp. 297-314
    • Heinrich, P.C.1    Behrmann, I.2    Muller-Newen, G.3    Schaper, F.4    Graeve, L.5
  • 10
    • 0029941260 scopus 로고    scopus 로고
    • Complex of the soluble IL-11 receptor and IL-11 acts as IL-6-type cytokine in hepatic and nonhepatic cells
    • Baumann H, Wang Y, Morella KK, Lai CF, Dams H, Hilton DJ, Hawley RG, Mackiewicz A. Complex of the soluble IL-11 receptor and IL-11 acts as IL-6-type cytokine in hepatic and nonhepatic cells. J Immunol 1996, 157(1):284-290.
    • (1996) J Immunol , vol.157 , Issue.1 , pp. 284-290
    • Baumann, H.1    Wang, Y.2    Morella, K.K.3    Lai, C.F.4    Dams, H.5    Hilton, D.J.6    Hawley, R.G.7    Mackiewicz, A.8
  • 11
    • 0030668919 scopus 로고    scopus 로고
    • Recombinant soluble interleukin-11 (IL-11) receptor alpha-chain can act as an IL-11 antagonist
    • Curtis DJ, Hilton DJ, Roberts B, Murray L, Nicola N, Begley CG. Recombinant soluble interleukin-11 (IL-11) receptor alpha-chain can act as an IL-11 antagonist. Blood 1997, 90(11):4403-4412.
    • (1997) Blood , vol.90 , Issue.11 , pp. 4403-4412
    • Curtis, D.J.1    Hilton, D.J.2    Roberts, B.3    Murray, L.4    Nicola, N.5    Begley, C.G.6
  • 12
    • 0029791740 scopus 로고    scopus 로고
    • Mediation of interleukin-11-dependent biological responses by a soluble form of the interleukin-11 receptor
    • 1217647, 8809037
    • Karow J, Hudson KR, Hall MA, Vernallis AB, Taylor JA, Gossler A, Heath JK. Mediation of interleukin-11-dependent biological responses by a soluble form of the interleukin-11 receptor. Biochem J 1996, 318(Pt 2):489-495. 1217647, 8809037.
    • (1996) Biochem J , vol.318 , Issue.PART 2 , pp. 489-495
    • Karow, J.1    Hudson, K.R.2    Hall, M.A.3    Vernallis, A.B.4    Taylor, J.A.5    Gossler, A.6    Heath, J.K.7
  • 13
    • 0032967716 scopus 로고    scopus 로고
    • A fusion protein of interleukin-11 and soluble interleukin-11 receptor acts as a superagonist on cells expressing gp130
    • 10.1016/S0014-5793(99)00477-9, 10350068
    • Pflanz S, Tacken I, Grotzinger J, Jacques Y, Minvielle S, Dahmen H, Heinrich PC, Muller-Newen G. A fusion protein of interleukin-11 and soluble interleukin-11 receptor acts as a superagonist on cells expressing gp130. FEBS Lett 1999, 450(1-2):117-122. 10.1016/S0014-5793(99)00477-9, 10350068.
    • (1999) FEBS Lett , vol.450 , Issue.1-2 , pp. 117-122
    • Pflanz, S.1    Tacken, I.2    Grotzinger, J.3    Jacques, Y.4    Minvielle, S.5    Dahmen, H.6    Heinrich, P.C.7    Muller-Newen, G.8
  • 15
    • 0036310997 scopus 로고    scopus 로고
    • Differential response of neuronal cells to a fusion protein of ciliary neurotrophic factor/soluble CNTF-receptor and leukemia inhibitory factor
    • 10.1046/j.1432-1033.2002.02977.x, 12071967
    • Marz P, Ozbek S, Fischer M, Voltz N, Otten U, Rose-John S. Differential response of neuronal cells to a fusion protein of ciliary neurotrophic factor/soluble CNTF-receptor and leukemia inhibitory factor. Eur J Biochem 2002, 269(12):3023-3031. 10.1046/j.1432-1033.2002.02977.x, 12071967.
    • (2002) Eur J Biochem , vol.269 , Issue.12 , pp. 3023-3031
    • Marz, P.1    Ozbek, S.2    Fischer, M.3    Voltz, N.4    Otten, U.5    Rose-John, S.6
  • 17
    • 33748742271 scopus 로고    scopus 로고
    • Protein N-glycosylation in the baculovirus-insect cell expression system and engineering of insect cells to produce "mammalianized" recombinant glycoproteins
    • Harrison RL, Jarvis DL. Protein N-glycosylation in the baculovirus-insect cell expression system and engineering of insect cells to produce "mammalianized" recombinant glycoproteins. Adv Virus Res 2006, 68:159-191.
    • (2006) Adv Virus Res , vol.68 , pp. 159-191
    • Harrison, R.L.1    Jarvis, D.L.2
  • 18
    • 0035896394 scopus 로고    scopus 로고
    • Structure of an extracellular gp130 cytokine receptor signaling complex
    • 10.1126/science.1058308, 11251120
    • Chow D, He X, Snow AL, Rose-John S, Garcia KC. Structure of an extracellular gp130 cytokine receptor signaling complex. Science 2001, 291(5511):2150-2155. 10.1126/science.1058308, 11251120.
    • (2001) Science , vol.291 , Issue.5511 , pp. 2150-2155
    • Chow, D.1    He, X.2    Snow, A.L.3    Rose-John, S.4    Garcia, K.C.5
  • 21
    • 0033565363 scopus 로고    scopus 로고
    • A role for the immunoglobulin-like domain of the human IL-6 receptor. Intracellular protein transport and shedding
    • 10.1046/j.1432-1327.1999.00511.x, 10406952
    • Vollmer P, Oppmann B, Voltz N, Fischer M, Rose-John S. A role for the immunoglobulin-like domain of the human IL-6 receptor. Intracellular protein transport and shedding. Eur J Biochem 1999, 263(2):438-446. 10.1046/j.1432-1327.1999.00511.x, 10406952.
    • (1999) Eur J Biochem , vol.263 , Issue.2 , pp. 438-446
    • Vollmer, P.1    Oppmann, B.2    Voltz, N.3    Fischer, M.4    Rose-John, S.5
  • 22
    • 0029938553 scopus 로고    scopus 로고
    • Structural analysis of the gene encoding the murine interleukin-11 receptor alpha-chain and a related locus
    • 10.1074/jbc.271.23.13754, 8662802
    • Robb L, Hilton DJ, Willson TA, Begley CG. Structural analysis of the gene encoding the murine interleukin-11 receptor alpha-chain and a related locus. J Biol Chem 1996, 271(23):13754-13761. 10.1074/jbc.271.23.13754, 8662802.
    • (1996) J Biol Chem , vol.271 , Issue.23 , pp. 13754-13761
    • Robb, L.1    Hilton, D.J.2    Willson, T.A.3    Begley, C.G.4
  • 23
    • 34648833029 scopus 로고    scopus 로고
    • Delivering new insight into the biology of megakaryopoiesis and thrombopoiesis
    • 10.1097/MOH.0b013e3282bad151, 17934346
    • Battinelli EM, Hartwig JH, Italiano JE. Delivering new insight into the biology of megakaryopoiesis and thrombopoiesis. Curr Opin Hematol 2007, 14(5):419-426. 10.1097/MOH.0b013e3282bad151, 17934346.
    • (2007) Curr Opin Hematol , vol.14 , Issue.5 , pp. 419-426
    • Battinelli, E.M.1    Hartwig, J.H.2    Italiano, J.E.3
  • 24
    • 17544382146 scopus 로고    scopus 로고
    • Interleukin-6 family of cytokines induced activation of different functional sites expressed by gp130 transducing protein
    • 10.1074/jbc.271.25.14764, 8662918
    • Chevalier S, Fourcin M, Robledo O, Wijdenes J, Pouplard-Barthelaix A, Gascan H. Interleukin-6 family of cytokines induced activation of different functional sites expressed by gp130 transducing protein. J Biol Chem 1996, 271(25):14764-14772. 10.1074/jbc.271.25.14764, 8662918.
    • (1996) J Biol Chem , vol.271 , Issue.25 , pp. 14764-14772
    • Chevalier, S.1    Fourcin, M.2    Robledo, O.3    Wijdenes, J.4    Pouplard-Barthelaix, A.5    Gascan, H.6
  • 25
    • 0029617757 scopus 로고
    • Interleukin-6 signal transducer gp130 has specific binding sites for different cytokines as determined by antagonistic and agonistic anti-gp130 monoclonal antibodies
    • 10.1002/eji.1830251240, 8566040
    • Wijdenes J, Heinrich PC, Muller-Newen G, Roche C, Gu ZJ, Clement C, Klein B. Interleukin-6 signal transducer gp130 has specific binding sites for different cytokines as determined by antagonistic and agonistic anti-gp130 monoclonal antibodies. Eur J Immunol 1995, 25(12):3474-3481. 10.1002/eji.1830251240, 8566040.
    • (1995) Eur J Immunol , vol.25 , Issue.12 , pp. 3474-3481
    • Wijdenes, J.1    Heinrich, P.C.2    Muller-Newen, G.3    Roche, C.4    Gu, Z.J.5    Clement, C.6    Klein, B.7
  • 26
    • 70449725291 scopus 로고    scopus 로고
    • IL-11 regulates autoimmune demyelination
    • 10.4049/jimmunol.0900622, 3027139, 19734214
    • Gurfein BT, Zhang Y, Lopez CB, Argaw AT, Zameer A, Moran TM, John GR. IL-11 regulates autoimmune demyelination. J Immunol 2009, 183(7):4229-4240. 10.4049/jimmunol.0900622, 3027139, 19734214.
    • (2009) J Immunol , vol.183 , Issue.7 , pp. 4229-4240
    • Gurfein, B.T.1    Zhang, Y.2    Lopez, C.B.3    Argaw, A.T.4    Zameer, A.5    Moran, T.M.6    John, G.R.7
  • 27
    • 0031916723 scopus 로고    scopus 로고
    • Infertility in female mice lacking the receptor for interleukin 11 is due to a defective uterine response to implantation
    • 10.1038/nm0398-303, 9500603
    • Robb L, Li R, Hartley L, Nandurkar HH, Koentgen F, Begley CG. Infertility in female mice lacking the receptor for interleukin 11 is due to a defective uterine response to implantation. Nat Med 1998, 4(3):303-308. 10.1038/nm0398-303, 9500603.
    • (1998) Nat Med , vol.4 , Issue.3 , pp. 303-308
    • Robb, L.1    Li, R.2    Hartley, L.3    Nandurkar, H.H.4    Koentgen, F.5    Begley, C.G.6
  • 30
    • 0026782577 scopus 로고
    • Complex of soluble human IL-6-receptor/IL-6 up-regulates expression of acute-phase proteins
    • Mackiewicz A, Schooltink H, Heinrich PC, Rose-John S. Complex of soluble human IL-6-receptor/IL-6 up-regulates expression of acute-phase proteins. J Immunol 1992, 149(6):2021-2027.
    • (1992) J Immunol , vol.149 , Issue.6 , pp. 2021-2027
    • Mackiewicz, A.1    Schooltink, H.2    Heinrich, P.C.3    Rose-John, S.4
  • 31
    • 14144251446 scopus 로고    scopus 로고
    • Dynamics of the gp130 cytokine complex: a model for assembly on the cellular membrane
    • 10.1110/ps.041117105, 2279283, 15722452
    • Schroers A, Hecht O, Kallen KJ, Pachta M, Rose-John S, Grotzinger J. Dynamics of the gp130 cytokine complex: a model for assembly on the cellular membrane. Protein Sci 2005, 14(3):783-790. 10.1110/ps.041117105, 2279283, 15722452.
    • (2005) Protein Sci , vol.14 , Issue.3 , pp. 783-790
    • Schroers, A.1    Hecht, O.2    Kallen, K.J.3    Pachta, M.4    Rose-John, S.5    Grotzinger, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.