메뉴 건너뛰기




Volumn 33, Issue 2, 2012, Pages 224-232

Quantitative assessment of the embryotoxic potential of NSO-heterocyclic compounds using zebrafish (Danio rerio)

Author keywords

Embryo toxicity; Fish embryo toxicity test; Heterocyclic aromatic compounds; NSO HET; Zebrafish

Indexed keywords

2,3 DIMETHYLBENZOFURAN; 6 METHYLQUINOLINE; ACRIDINE; BENZOFURAN; BENZOTHIOPENE; CARBAZOLE; COLLIDINE; DIBENZOFURAN; DIBENZOTHIOPENE; HETEROCYCLIC COMPOUND; METHYLBENZOFURAN; PICOLINE; PYRIDINE; QUINOLINE; UNCLASSIFIED DRUG; XANTHENE;

EID: 84858439206     PISSN: 08906238     EISSN: 18731708     Source Type: Journal    
DOI: 10.1016/j.reprotox.2011.12.005     Document Type: Article
Times cited : (58)

References (53)
  • 1
    • 0038796497 scopus 로고    scopus 로고
    • Effect-directed identification of oxygen and sulfur heterocycles as major polycyclic aromatic cytochrome P4501A-inducers in a contaminated sediment
    • Brack W., Schirmer K. Effect-directed identification of oxygen and sulfur heterocycles as major polycyclic aromatic cytochrome P4501A-inducers in a contaminated sediment. Environ Sci Technol 2003, 37:3062-3070.
    • (2003) Environ Sci Technol , vol.37 , pp. 3062-3070
    • Brack, W.1    Schirmer, K.2
  • 2
    • 48349107135 scopus 로고    scopus 로고
    • Dioxin- and POP-contaminated sites-contemporary and future relevance and challenges: overview on background, aims and scope of the series
    • Weber R., Gaus C., Tysklind M., Johnston P., Forter M., Hollert H., et al. Dioxin- and POP-contaminated sites-contemporary and future relevance and challenges: overview on background, aims and scope of the series. Environ Sci Pollut Res 2008, 15:363-393.
    • (2008) Environ Sci Pollut Res , vol.15 , pp. 363-393
    • Weber, R.1    Gaus, C.2    Tysklind, M.3    Johnston, P.4    Forter, M.5    Hollert, H.6
  • 3
    • 80055024298 scopus 로고    scopus 로고
    • Importance of heterocyclic aromatic compounds in monitored natural attenuation for coal tar contaminated aquifers: a review
    • Blum P., Sagner A., Tiehm A., Martus P., Wendel T., Grathwohl P. Importance of heterocyclic aromatic compounds in monitored natural attenuation for coal tar contaminated aquifers: a review. J Contam Hydrol 2011, 126:181-194. 10.1016/j.jconhyd.2011.08.004.
    • (2011) J Contam Hydrol , vol.126 , pp. 181-194
    • Blum, P.1    Sagner, A.2    Tiehm, A.3    Martus, P.4    Wendel, T.5    Grathwohl, P.6
  • 4
    • 80051672342 scopus 로고    scopus 로고
    • Identifikation NSO-heterocyclischer Prioritärsubstanzen zur Erkundung und überwachung Teeröl-kontaminierter Standorte
    • Blotevogel J., Reineke A.K., Hollender J., Held T. Identifikation NSO-heterocyclischer Prioritärsubstanzen zur Erkundung und überwachung Teeröl-kontaminierter Standorte. Grundwasser 2008, 13:147-157.
    • (2008) Grundwasser , vol.13 , pp. 147-157
    • Blotevogel, J.1    Reineke, A.K.2    Hollender, J.3    Held, T.4
  • 5
    • 0025261706 scopus 로고
    • Biodegradation of azo and heterocyclic dyes by Phanerochaete chrysosporium
    • Cripps C., Bumpus J.A., Aust S.D. Biodegradation of azo and heterocyclic dyes by Phanerochaete chrysosporium. Appl Environ Microbiol 1990, 56:1114-1118.
    • (1990) Appl Environ Microbiol , vol.56 , pp. 1114-1118
    • Cripps, C.1    Bumpus, J.A.2    Aust, S.D.3
  • 6
    • 4344612574 scopus 로고    scopus 로고
    • Selection of heterocycles for drug design
    • Broughton H.B., Watson I.A. Selection of heterocycles for drug design. J Mol Graph Model 2004, 23:51-58.
    • (2004) J Mol Graph Model , vol.23 , pp. 51-58
    • Broughton, H.B.1    Watson, I.A.2
  • 7
    • 0037169146 scopus 로고    scopus 로고
    • Comparative evaluation of the effects of pesticides in acute toxicity luminescence bioassays
    • Fernández-Alba A.R., Guil M.D.H., López G.D., Chisti Y. Comparative evaluation of the effects of pesticides in acute toxicity luminescence bioassays. Anal Chim Acta 2002, 451:195-202.
    • (2002) Anal Chim Acta , vol.451 , pp. 195-202
    • Fernández-Alba, A.R.1    Guil, M.D.H.2    López, G.D.3    Chisti, Y.4
  • 8
    • 0030613013 scopus 로고    scopus 로고
    • Biodegradation of NSO-compounds under different redox-conditions
    • Dyreborg S., Arvin E., Broholm K. Biodegradation of NSO-compounds under different redox-conditions. J Contam Hydrol 1997, 25:177-197.
    • (1997) J Contam Hydrol , vol.25 , pp. 177-197
    • Dyreborg, S.1    Arvin, E.2    Broholm, K.3
  • 9
    • 84858448405 scopus 로고    scopus 로고
    • Mikrobieller Abbau typischer Teeröl-PAK und Hetero-PAK (N,S,O) in einem Modellbodenhorizont
    • Meyer S. Mikrobieller Abbau typischer Teeröl-PAK und Hetero-PAK (N,S,O) in einem Modellbodenhorizont. PhD Thesis. Hamburg, Germany: Hamburg University; 1999.
    • (1999) Hamburg, Germany: Hamburg University
    • Meyer, S.1
  • 10
    • 0031026829 scopus 로고    scopus 로고
    • Transformation of indole and quinoline by Desulfobacterium indolicum (DSM 3383)
    • Licht D., Johansen S.S., Arvin E., Ahring B.K. Transformation of indole and quinoline by Desulfobacterium indolicum (DSM 3383). Appl Microbiol Biotechnol 1997, 47:167-172.
    • (1997) Appl Microbiol Biotechnol , vol.47 , pp. 167-172
    • Licht, D.1    Johansen, S.S.2    Arvin, E.3    Ahring, B.K.4
  • 11
    • 0033980904 scopus 로고    scopus 로고
    • Effects of heterocyclic PAHs (N, S, O) on the biodegradation of typical tar oil PAHs in a soil/compost mixture
    • Meyer S., Steinhart H. Effects of heterocyclic PAHs (N, S, O) on the biodegradation of typical tar oil PAHs in a soil/compost mixture. Chemosphere 2000, 40:359-367.
    • (2000) Chemosphere , vol.40 , pp. 359-367
    • Meyer, S.1    Steinhart, H.2
  • 12
    • 48349139224 scopus 로고    scopus 로고
    • Changes in toxicity and Ah receptor agonist activity of suspended particulate matter during flood events at the rivers Neckar and Rhine - a mass balance approach using in vitro methods and chemical analysis
    • Wölz J., Engwall M., Maletz S., Takner H.O., van Bavel B., Kammann U., et al. Changes in toxicity and Ah receptor agonist activity of suspended particulate matter during flood events at the rivers Neckar and Rhine - a mass balance approach using in vitro methods and chemical analysis. Environ Sci Pollut Res 2008, 15:536-553.
    • (2008) Environ Sci Pollut Res , vol.15 , pp. 536-553
    • Wölz, J.1    Engwall, M.2    Maletz, S.3    Takner, H.O.4    van Bavel, B.5    Kammann, U.6
  • 13
    • 43349100198 scopus 로고    scopus 로고
    • Activities and identification of aryl hydrocarbon receptor agonists in sediments from the Danube river
    • Keiter S., Grund S., van Bavel B., Hagberg J., Engwall M., Kammann U., et al. Activities and identification of aryl hydrocarbon receptor agonists in sediments from the Danube river. Anal Bioanal Chem 2008, 390:2009-2019.
    • (2008) Anal Bioanal Chem , vol.390 , pp. 2009-2019
    • Keiter, S.1    Grund, S.2    van Bavel, B.3    Hagberg, J.4    Engwall, M.5    Kammann, U.6
  • 15
    • 0003186730 scopus 로고    scopus 로고
    • European Commission Directive 2000/60/EC of the European Parliament and of the Council of 23 October 2000 establishing a framework for Community action in the field of water policy
    • European Commission Directive 2000/60/EC of the European Parliament and of the Council of 23 October 2000 establishing a framework for Community action in the field of water policy. Off J Eur Union 2000, L327:1-72.
    • (2000) Off J Eur Union , vol.L327 , pp. 1-72
  • 16
    • 2642555551 scopus 로고    scopus 로고
    • Relative potency of PAHs and heterocycles as aryl hydrocarbon receptor agonists in fish
    • Barron M.G., Heintz R., Rice S.D. Relative potency of PAHs and heterocycles as aryl hydrocarbon receptor agonists in fish. Mar Environ Res 2004, 58:95-100.
    • (2004) Mar Environ Res , vol.58 , pp. 95-100
    • Barron, M.G.1    Heintz, R.2    Rice, S.D.3
  • 17
    • 46949096699 scopus 로고    scopus 로고
    • Heterocyclic compounds: toxic effects using algae, daphnids, and the Salmonella/microsome test taking methodical quantitative aspects into account
    • Eisentraeger A., Brinkmann C., Hollert H., Sagner A., Tiehm A., Neuwoehner J. Heterocyclic compounds: toxic effects using algae, daphnids, and the Salmonella/microsome test taking methodical quantitative aspects into account. Environ Toxicol Chem 2008, 27:1590-1596.
    • (2008) Environ Toxicol Chem , vol.27 , pp. 1590-1596
    • Eisentraeger, A.1    Brinkmann, C.2    Hollert, H.3    Sagner, A.4    Tiehm, A.5    Neuwoehner, J.6
  • 18
    • 4544295743 scopus 로고    scopus 로고
    • DNA damage and micronuclei induced in rat and human kidney cells by six chemicals carcinogenic to the rat kidney
    • Robbiano L., Baroni D., Carrozzino R., Mereto E., Brambilla G. DNA damage and micronuclei induced in rat and human kidney cells by six chemicals carcinogenic to the rat kidney. Toxicology 2004, 204:187-195.
    • (2004) Toxicology , vol.204 , pp. 187-195
    • Robbiano, L.1    Baroni, D.2    Carrozzino, R.3    Mereto, E.4    Brambilla, G.5
  • 19
    • 0035122719 scopus 로고    scopus 로고
    • Development of QSARs to investigate the bacterial toxicity and biotransformation potential of aromatic heterocyclic compounds
    • Bundy J.G., Morriss A.W.J., Durham D.G., Campbell C.D., Paton G.I. Development of QSARs to investigate the bacterial toxicity and biotransformation potential of aromatic heterocyclic compounds. Chemosphere 2001, 42:885-892.
    • (2001) Chemosphere , vol.42 , pp. 885-892
    • Bundy, J.G.1    Morriss, A.W.J.2    Durham, D.G.3    Campbell, C.D.4    Paton, G.I.5
  • 20
    • 0035166184 scopus 로고    scopus 로고
    • Cytochrome P450 induction by nitrated polycyclic aromatic hydrocarbons, azaarenes, and binary mixtures in fish hepatoma cell line PLHC-1
    • Jung D.K.J., Klaus T., Fent K. Cytochrome P450 induction by nitrated polycyclic aromatic hydrocarbons, azaarenes, and binary mixtures in fish hepatoma cell line PLHC-1. Environ Toxicol Chem 2001, 20:149-159.
    • (2001) Environ Toxicol Chem , vol.20 , pp. 149-159
    • Jung, D.K.J.1    Klaus, T.2    Fent, K.3
  • 21
    • 33746661647 scopus 로고    scopus 로고
    • Effects of N-heterocyclic polyaromatic hydrocarbons on survival, reproduction, and biochemical parameters in Daphnia magna
    • Feldmannová M., Hilscherová K., Maršálek B., Bláha L. Effects of N-heterocyclic polyaromatic hydrocarbons on survival, reproduction, and biochemical parameters in Daphnia magna. Environ Toxicol 2006, 21:425-431.
    • (2006) Environ Toxicol , vol.21 , pp. 425-431
    • Feldmannová, M.1    Hilscherová, K.2    Maršálek, B.3    Bláha, L.4
  • 22
    • 33749080115 scopus 로고    scopus 로고
    • Cytotoxicity and aryl hydrocarbon receptor-mediated activity of N-heterocyclic polycyclic aromatic hydrocarbons: structure-activity relationships
    • Sovadinová I., Bláha L., Janoscaronek J., Hilscherová K., Giesy J.P., Jones J.G., et al. Cytotoxicity and aryl hydrocarbon receptor-mediated activity of N-heterocyclic polycyclic aromatic hydrocarbons: structure-activity relationships. Environ Toxicol Chem 2006, 25:1291-1297.
    • (2006) Environ Toxicol Chem , vol.25 , pp. 1291-1297
    • Sovadinová, I.1    Bláha, L.2    Janoscaronek, J.3    Hilscherová, K.4    Giesy, J.P.5    Jones, J.G.6
  • 23
    • 80051668115 scopus 로고    scopus 로고
    • Some heterocyclic aromatic compounds are Ah receptor agonists in the DR-Calux and the EROD assay with RTL-W1 cells
    • Hinger G., Brinkmann M., Bluhm K., Sagner A., Takner H., Eisenträger A., et al. Some heterocyclic aromatic compounds are Ah receptor agonists in the DR-Calux and the EROD assay with RTL-W1 cells. Environ Sci Pollut Res 2011, 18:1297-1304.
    • (2011) Environ Sci Pollut Res , vol.18 , pp. 1297-1304
    • Hinger, G.1    Brinkmann, M.2    Bluhm, K.3    Sagner, A.4    Takner, H.5    Eisenträger, A.6
  • 24
    • 0032794133 scopus 로고    scopus 로고
    • Effects of exposure to Azaarenes on emergence and mouthpart development in the midge Chironomus riparius (Diptera: Chironomidae)
    • Bleeker E.A.J., Leslie H.A., Groenendijk D., Plans M., Admiraal W. Effects of exposure to Azaarenes on emergence and mouthpart development in the midge Chironomus riparius (Diptera: Chironomidae). Environ Toxicol Chem 1999, 18:1829-1834.
    • (1999) Environ Toxicol Chem , vol.18 , pp. 1829-1834
    • Bleeker, E.A.J.1    Leslie, H.A.2    Groenendijk, D.3    Plans, M.4    Admiraal, W.5
  • 25
    • 84858448193 scopus 로고    scopus 로고
    • Draft detailed review paper on fish embryo toxicity assay. Report prepared to the German Federal Environmental Agency (UBA Contract Number 203 85 422)
    • Braunbeck T, Lammer E. Draft detailed review paper on fish embryo toxicity assay. Report prepared to the German Federal Environmental Agency (UBA Contract Number 203 85 422). Environ Sci Pollut Res 2005;15:394-404.
    • (2005) Environ Sci Pollut Res , vol.15 , pp. 394-404
    • Braunbeck, T.1    Lammer, E.2
  • 26
    • 48349111923 scopus 로고    scopus 로고
    • The zebrafish embryo model in environmental risk assessment-applications beyond acute toxicity testing
    • Scholz S., Fischer S., Gündel U., Küster E., Luckenbach T., Voelker D. The zebrafish embryo model in environmental risk assessment-applications beyond acute toxicity testing. Environ Sci Pollut Res 2008, 15:394-404.
    • (2008) Environ Sci Pollut Res , vol.15 , pp. 394-404
    • Scholz, S.1    Fischer, S.2    Gündel, U.3    Küster, E.4    Luckenbach, T.5    Voelker, D.6
  • 27
    • 0028990054 scopus 로고
    • Comparison of testing acute toxicity on zebrafish, Brachydanio rerio and RTG-2 cytotoxicity as possible alternatives to the acute fish test
    • Lange M., Gebauer W., Markl J., Nagel R. Comparison of testing acute toxicity on zebrafish, Brachydanio rerio and RTG-2 cytotoxicity as possible alternatives to the acute fish test. Chemosphere 1995, 30:2087-2102.
    • (1995) Chemosphere , vol.30 , pp. 2087-2102
    • Lange, M.1    Gebauer, W.2    Markl, J.3    Nagel, R.4
  • 28
    • 0036048386 scopus 로고    scopus 로고
    • DarT. The embryo test with the zebrafish Danio rerio - a general model in ecotoxicology and toxicology
    • Nagel R. DarT. The embryo test with the zebrafish Danio rerio - a general model in ecotoxicology and toxicology. ALTEX 2002, 19:38-48.
    • (2002) ALTEX , vol.19 , pp. 38-48
    • Nagel, R.1
  • 29
    • 0036139451 scopus 로고    scopus 로고
    • Effects of eight polycyclic aromatic compounds on the survival and reproduction of Enchytraeus crypticus (Oligochaeta, Clitellata)
    • Sverdrup L.E., Jensen J., Kelley A.E., Krogh P.H., Stenersen J. Effects of eight polycyclic aromatic compounds on the survival and reproduction of Enchytraeus crypticus (Oligochaeta, Clitellata). Environ Toxicol Chem 2002, 21:109-114.
    • (2002) Environ Toxicol Chem , vol.21 , pp. 109-114
    • Sverdrup, L.E.1    Jensen, J.2    Kelley, A.E.3    Krogh, P.H.4    Stenersen, J.5
  • 30
    • 33947305120 scopus 로고    scopus 로고
    • Physicochemical substance properties as indicators for unreliable exposure in microplate-based bioassays
    • Riedl J., Altenburger R. Physicochemical substance properties as indicators for unreliable exposure in microplate-based bioassays. Chemosphere 2007, 67:2210-2220.
    • (2007) Chemosphere , vol.67 , pp. 2210-2220
    • Riedl, J.1    Altenburger, R.2
  • 31
    • 48949089860 scopus 로고    scopus 로고
    • How to deal with lipophilic and volatile organic substances in microtiter plate assays
    • Schreiber R., Altenburger R., Paschke A., Küster E. How to deal with lipophilic and volatile organic substances in microtiter plate assays. Environ Toxicol Chem 2008, 27:1676-1862.
    • (2008) Environ Toxicol Chem , vol.27 , pp. 1676-1862
    • Schreiber, R.1    Altenburger, R.2    Paschke, A.3    Küster, E.4
  • 32
    • 84858439100 scopus 로고    scopus 로고
    • Toxizität und mikrobiologischer Abbau heterozyklischer Kohlenwasserstoffe. Veröffentlichungen aus dem Technologiezentrum Wasser Karlsruhe (ISSN 1434-5765)
    • Sagner A. Vorkommen, Toxizität und mikrobiologischer Abbau heterozyklischer Kohlenwasserstoffe. Veröffentlichungen aus dem Technologiezentrum Wasser Karlsruhe (ISSN 1434-5765), Band 41: 151 Seiten; 2009.
    • (2009) Band 41: 151 Seiten
    • Sagner, A.V.1
  • 34
    • 84858445240 scopus 로고    scopus 로고
    • DIN. German standard methods for the examination of water, waste water and sludge - subanimal testing (group T) - Part 6: Toxicity to fish. Determination of the non-acute-poisonous effect of waste water to fish eggs by dilution limits (T 6). DIN 38415-6; German Standardization Organization.
    • DIN. German standard methods for the examination of water, waste water and sludge - subanimal testing (group T) - Part 6: Toxicity to fish. Determination of the non-acute-poisonous effect of waste water to fish eggs by dilution limits (T 6). DIN 38415-6; German Standardization Organization. 2009.
    • (2009)
  • 35
    • 84858445241 scopus 로고    scopus 로고
    • OECD. Fish embryo toxicity (FET) test. Draft OECD guideline for the testing of chemicals;. Available from
    • OECD. Fish embryo toxicity (FET) test. Draft OECD guideline for the testing of chemicals; 2006. Available from http://wwwoecdorg/dataoecd/39/59/36817070pdf.
    • (2006)
  • 36
    • 84858448406 scopus 로고    scopus 로고
    • ISO 7346-3. Water quality - determination of the acute lethal toxicity of substances to a freshwater fish (Brachydanio rerio Hamilton-Buchanan (Teleostei, Cyprinidae)) - Part 3: Flow-through method. International Organization for Standardization, Geneva, Switzerland;
    • ISO 7346-3. Water quality - determination of the acute lethal toxicity of substances to a freshwater fish (Brachydanio rerio Hamilton-Buchanan (Teleostei, Cyprinidae)) - Part 3: Flow-through method. International Organization for Standardization, Geneva, Switzerland; 1996.
    • (1996)
  • 40
    • 0021344946 scopus 로고
    • Toxicity accumulation and elimination of polycyclic aromatic sulfur heterocycles in Daphnia magna
    • Eastmond D.A., Booth G.M., Lee M.L. Toxicity accumulation and elimination of polycyclic aromatic sulfur heterocycles in Daphnia magna. Arch Environ Contam Toxicol 1984, 13:105-111.
    • (1984) Arch Environ Contam Toxicol , vol.13 , pp. 105-111
    • Eastmond, D.A.1    Booth, G.M.2    Lee, M.L.3
  • 41
    • 70349439013 scopus 로고    scopus 로고
    • Development of a flow-through system for the fish embryo toxicity test (FET) with the zebrafish (Danio rerio)
    • Lammer E., Kamp H.G., Hisgen V., Koch M., Reinhard D., Salinas E.R., et al. Development of a flow-through system for the fish embryo toxicity test (FET) with the zebrafish (Danio rerio). Toxicol. In Vitro 2009, 23:1436-1442.
    • (2009) Toxicol. In Vitro , vol.23 , pp. 1436-1442
    • Lammer, E.1    Kamp, H.G.2    Hisgen, V.3    Koch, M.4    Reinhard, D.5    Salinas, E.R.6
  • 42
    • 54749136995 scopus 로고    scopus 로고
    • Passive dosing of soil invertebrates with polycyclic aromatic hydrocarbons: limited chemical activity explains toxicity cutoff
    • Mayer P., Holmstrup M. Passive dosing of soil invertebrates with polycyclic aromatic hydrocarbons: limited chemical activity explains toxicity cutoff. Environ Sci Technol 2008, 42:7516-7521.
    • (2008) Environ Sci Technol , vol.42 , pp. 7516-7521
    • Mayer, P.1    Holmstrup, M.2
  • 43
    • 77952105229 scopus 로고    scopus 로고
    • Controlling and maintaining exposure of hydrophobic organic compounds in aquatic toxicity tests by passive dosing
    • Smith K.E.C., Dom N., Blust R., Mayer P. Controlling and maintaining exposure of hydrophobic organic compounds in aquatic toxicity tests by passive dosing. Aqua Toxicol 2010, 98:15-24.
    • (2010) Aqua Toxicol , vol.98 , pp. 15-24
    • Smith, K.E.C.1    Dom, N.2    Blust, R.3    Mayer, P.4
  • 44
    • 84858448517 scopus 로고    scopus 로고
    • Passive dosing can contribute to the reliability of in-vitro effect data of PAHs from the fish embryo test with Danio rerio
    • submitted for publication.
    • Seiler TB, Best N, Møller Fernqvist M, Smith K, Braunbeck T, Mayer M, et al. Passive dosing can contribute to the reliability of in-vitro effect data of PAHs from the fish embryo test with Danio rerio. Chemosphere 2012, submitted for publication.
    • (2012) Chemosphere
    • Seiler, T.B.1    Best, N.2    Møller Fernqvist, M.3    Smith, K.4    Braunbeck, T.5    Mayer, M.6
  • 45
    • 84858445239 scopus 로고    scopus 로고
    • US EPA. EPA's office of Pollution Prevention Toxics and Syracuse Research Corporation (SRC): Estimation Programs Interface Suite™. US Environmental Protection Agency; Episuite: Henry Program v 3.10: bond contribution; Episuite WSKOW-Program; Episuite KOWIN-Program; Episuite ECOSAR-Program
    • US EPA. EPA's office of Pollution Prevention Toxics and Syracuse Research Corporation (SRC): Estimation Programs Interface Suite™. US Environmental Protection Agency; Episuite: Henry Program v 3.10: bond contribution; Episuite WSKOW-Program; Episuite KOWIN-Program; Episuite ECOSAR-Program; 2009.
    • (2009)
  • 46
    • 0026785215 scopus 로고
    • Classifying environmental pollutants. 1. Structure-activity relationships for prediction of aquatic toxicity
    • Verhaar H.J.M., van Leeuwen C.J., Hermens J.L.M. Classifying environmental pollutants. 1. Structure-activity relationships for prediction of aquatic toxicity. Chemosphere 1992, 25:471-491.
    • (1992) Chemosphere , vol.25 , pp. 471-491
    • Verhaar, H.J.M.1    van Leeuwen, C.J.2    Hermens, J.L.M.3
  • 47
    • 59149107232 scopus 로고    scopus 로고
    • Ecotoxicity of quinoline and hydroxylated derivatives and their occurrence in groundwater of a tar-contaminated field site
    • Neuwoehner J., Reineke A.-K., Hollender J., Eisentraeger A. Ecotoxicity of quinoline and hydroxylated derivatives and their occurrence in groundwater of a tar-contaminated field site. Ecotoxicol Environ Saf 2009, 72:819-827.
    • (2009) Ecotoxicol Environ Saf , vol.72 , pp. 819-827
    • Neuwoehner, J.1    Reineke, A.-K.2    Hollender, J.3    Eisentraeger, A.4
  • 48
    • 63949085053 scopus 로고    scopus 로고
    • Is the fish embryo toxicity test (FET) with the zebrafish (Danio rerio) a potential alternative for the fish acute toxicity test
    • Lammer E., Carr G.J., Wendler K., Rawlings J.M., Belanger S.E., Braunbeck T. Is the fish embryo toxicity test (FET) with the zebrafish (Danio rerio) a potential alternative for the fish acute toxicity test. Comp Biochem Physiol 2008, 149:196-209.
    • (2008) Comp Biochem Physiol , vol.149 , pp. 196-209
    • Lammer, E.1    Carr, G.J.2    Wendler, K.3    Rawlings, J.M.4    Belanger, S.E.5    Braunbeck, T.6
  • 49
    • 84858005332 scopus 로고    scopus 로고
    • Zebrafish embryos as an alternative to animal experiments-a commentary on the definition of the onset of protected life stages in animal welfare regulations
    • (in press).
    • Strähle U, Scholz S, Geisler R, Greiner P, Hollert H, Rastegar R, et al. Zebrafish embryos as an alternative to animal experiments-a commentary on the definition of the onset of protected life stages in animal welfare regulations. Reprod Toxicol (in press).
    • Reprod Toxicol
    • Strähle, U.1    Scholz, S.2    Geisler, R.3    Greiner, P.4    Hollert, H.5    Rastegar, R.6
  • 50
    • 0018017210 scopus 로고
    • Bioaccumulation potential and acute toxicity of synthetic fuel effluents in freshwater biota: azzareenes
    • Southworth G.R., Beauchamp J.J., Schmieder P.K. Bioaccumulation potential and acute toxicity of synthetic fuel effluents in freshwater biota: azzareenes. Environ Sci Technol 1978, 12:1062-1066.
    • (1978) Environ Sci Technol , vol.12 , pp. 1062-1066
    • Southworth, G.R.1    Beauchamp, J.J.2    Schmieder, P.K.3
  • 51
    • 2642705137 scopus 로고    scopus 로고
    • Phytotoxicity of acridine, an important representative of a group of tar and creosote contaminants, N-Pac compounds
    • Gissel-Nielsen G., Nielson T. Phytotoxicity of acridine, an important representative of a group of tar and creosote contaminants, N-Pac compounds. Polycyclic Aromat Compd 1996, 8:243-249.
    • (1996) Polycyclic Aromat Compd , vol.8 , pp. 243-249
    • Gissel-Nielsen, G.1    Nielson, T.2
  • 53
    • 57149121176 scopus 로고    scopus 로고
    • Development of a groundwater biobarrier for the removal of PAH, BTEX, and heterocyclic hydrocarbons
    • Tiehm A., Müller A., Alt S., Jacob H., Schad H., Weingran C. Development of a groundwater biobarrier for the removal of PAH, BTEX, and heterocyclic hydrocarbons. Water Sci Technol 2008, 58:1349-1355.
    • (2008) Water Sci Technol , vol.58 , pp. 1349-1355
    • Tiehm, A.1    Müller, A.2    Alt, S.3    Jacob, H.4    Schad, H.5    Weingran, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.