Pharmacokinetics, metabolism and excretion of 14C-monoethyl phthalate (MEP) and 14C-diethyl phthalate (DEP) after single oral and IV administration in the juvenile dog

Xenobiotica

Volumn 42, Issue 4, 2012, Pages 389-397

  Kao, Mark L ^a   Ruoff, Bruce ^a   Bower, Nancy ^b   Aoki, Toyohiko ^c   Smart, Clair ^d   Mannens, Geert ^e  

^a JANSSEN RESEARCH AND DEVELOPMENT   (United States)

^b EISAI INC   (United States)

^c EISAI CO LTD   (Japan)

^d HUNTINGDON LIFE SCIENCES   (United Kingdom)

^e JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

Author keywords

Diethyl phthalate; metabolism; monoethyl phthalate; paediatric; pharmacokinetics; safety assessment

Indexed keywords

CARBON 14; PHTHALIC ACID; PHTHALIC ACID DIETHYL ESTER; PHTHALIC ACID ETHYL ESTER; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG EXCRETION; DRUG HALF LIFE; DRUG METABOLISM; DRUG URINE LEVEL; MALE; NONHUMAN;

ADMINISTRATION, ORAL; ANIMALS; CARBON RADIOISOTOPES; DOGS; HALF-LIFE; INJECTIONS, INTRAVENOUS; MALE; PHTHALIC ACIDS;

CANIS FAMILIARIS;

EID: 84858435879     PISSN: 00498254     EISSN: 13665928     Source Type: Journal    
DOI: 10.3109/00498254.2011.627478     Document Type: Article

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