Human papillomavirus sperm infection and assisted reproduction: A dangerous hazard with a possible safe solution

Human Reproduction

Volumn 27, Issue 4, 2012, Pages 967-973

  Garolla, Andrea ^a   Lenzi, Andrea ^b   Pal, Giorgio ^a   Pizzol, Damiano ^a   Bertoldo, Alessandro ^a   De Toni, Luca ^a   Foresta, Carlo ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

assisted reproduction; human papillomavirus; male infertility; sperm infection; sperm selection

Indexed keywords

HEPARIN; HEPARIN LYASE; HEPARINASE 3; UNCLASSIFIED DRUG;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOFLUOROMETRY; DNA FRAGMENTATION; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; HUMAN PAPILLOMAVIRUS TYPE 16; IMMUNOHISTOCHEMISTRY; MALE; MALE INFERTILITY; PAPILLOMAVIRUS INFECTION; SEMEN ANALYSIS; SPERM; VIRUS CAPSID; VIRUS DETECTION;

HUMAN PAPILLOMAVIRUS; HUMAN PAPILLOMAVIRUS TYPE 16; MIRIDAE;

EID: 84858406018     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/des009     Document Type: Article

References (33)

1. Alberico S, Pinzano R, Comar M, Toffoletti F, Maso G, Ricci G, Guaschino S. Maternal-fetal transmission of human papillomavirus. Minerva Ginecol 1996;48:199-204.
2. Armbruster-Moraes E, Ioshimoto LM, Leão E, Zugaib M. Presence of human papillomavirus DNA in amniotic fluids of pregnant women with cervical lesions. Gynecol Oncol 1994;54:152-158.
3. Barzon L, Militello V, Pagni S, Franchin E, Dal Bello F, Mengoli C, Palù G. Distribution of human papillomavirus types in the anogenital tract of females and males. J Med Virol 2010;82:1424-1430.
4. Calinisan JH, Chan SR, King A, Chan PJ. Human papillomavirus and blastocyst apoptosis. J Assist Reprod Genet 2002;19:132-136.
5. Ceballos A, Remes Lenicov F, Sabatté J, Rodríguez Rodrígues C, Cabrini M, Jancic C, Raiden S, Donaldson M, Agustín Pasqualini R Jr, Marin-Briggiler C et al. Spermatozoa capture HIV-1 through heparin sulfate and efficiently transmit the virus to dendritic cells. J Exp Med 2009;206:2717-2733.
6. Didelot-Rousseau MN, Diafouka F, Yayo E, Kouadio LP, Monnet D, Segondy M. HPV seminal shedding among men seeking fertility evaluation in Abidjan, Ivory Coast. J Clin Virol 2007;39:153-155.
7. D'Souza G, Kreimer AR, Viscidi R, Pawlita M, Fakhry C, Koch WM, Westra WH, Gillison ML. Case-control study of human papillomavirus and oropharyngeal cancer. N Engl J Med 2007; 356:1944-1956.
8. Favre M, Majewski S, De Jesus N, Malejczyk M, Orth G, Jablonska S. A possible vertical transmission of human papillomavirus genotypes associated with epidermodysplasia verruciformis. J Invest Dermatol 1998;111:333-336.
9. Foresta C, Pizzol D, Moretti A, Barzon L, Palù G, Garolla A. Clinical and prognostic significance of human papillomavirus DNA in the sperm or exfoliated cells of infertile patients and subjects with risk factors. Fertil Steril 2010;94:1723-1727.
10. Foresta C, Ferlin A, Bertoldo A, Patassini C, Zuccarello D, Garolla A. Human papilloma virus in the sperm cryobank: an emerging problem? Int J Androl 2011a;34:242-246.
11. Foresta C, Patassini C, Bertoldo A, Menegazzo M, Francavilla F, Barzon L, Ferlin A. Mechanism of human papillomavirus binding to human spermatozoa and fertilizing ability of infected spermatozoa. PLoS One 2011b;6:e15036.
12. Foresta C, Pizzol D, Bertoldo A, Menegazzo M, Barzon L, Garolla A. Semen washing procedures do not eliminate human papilloma virus sperm infection in infertile patients. Fertil Steril 2011c;96:1077-1082.
13. Giovannelli L, Migliore MC, Capra G, Caleca MP, Bellavia C, Perino A, Viviano E, Matranga D, Ammatuna P. Penile, urethral, and seminal sampling for diagnosis of human papillomavirus infection in men. J Clin Microbiol 2007;45:248-251.
14. Giuliano AR, Nielson CM, Flores R, Dunne EF, Abrahamsen M, Papenfuss MR, Markowitz LE, Smith D, Harris RB. The optimal anatomic sites for sampling heterosexual men for human papillomavirus (HPV) detection: the HPV detection in men study. J Infect Dis 2007;196:1146-1152.
15. Goldstone S, Palefsky JM, Giuliano AR, Moreira ED Jr, Aranda C, Jessen H, Hillman RJ, Ferris DG, Coutlee F, Liaw KL et al. Prevalence of and risk factors for human papillomavirus (HPV) infection among HIVseronegative men who have sex with men. J Infect Dis 2011;203:66-74.
16. Graziottin A, Serafini A. HPV infection in women: psychosexual impact of genital warts and intraepithelial lesions. J Sex Med 2009;6:633-645.
17. Henneberg AA, Patton WC, Jacobson JD, Chan PJ. Human papilloma virus DNA exposure and embryo survival is stage-specific. J Assist Reprod Genet 2006;23:255-259.
18. Hermonat PL, Han L, Wendel PJ, Quirk JG, Stern S, Lowery CL, Rechtin TM. Human papillomavirus is more prevalent in first trimester spontaneously aborted products of conception compared to elective specimens. Virus Genes 1997;14:13-17.
19. Kaspersen MD, Larsen PB, Ingerslev HJ, Fedder J, Petersen GB, Bonde J, Höllsberg P. Identification of multiple HPV types on spermatozoa from human sperm donors. PLoS One 2011;6:e18095.
20. Lee CA, Huang CT, King A, Chan PJ. Differential effects of human papillomavirus DNA types on p53 tumor-suppressor gene apoptosis in sperm. Gynecol Oncol 2002;85:511-516.
21. Nyitray AG, Carvalho da Silva RJ, Baggio ML, Lu B, Smith D, Abrahamsen M, Papenfuss M, Villa LL, Lazcano-Ponce E, Giuliano AR. Age-specific prevalence of and risk factors for anal human papillomavirus (HPV) among men who have sex with women and men who have sex with men: the HPV in men (HIM) study. J Infect Dis 2011;203:49-57.
22. Parkin DM. The global health burden of infection-associated cancers in the year 2002. Int J Cancer 2006;118:3030-3044.
23. Pérez-Andino J, Buck CB, Ribbeck K. Adsorption of human papillomavirus 16 to live human sperm. PLoS One 2009;4:e5847.
24. Perino A, Giovannelli L, Schillaci R, Ruvolo G, Fiorentino FP, Alimondi P, Cefalù E, Ammatuna P. Human papillomavirus infection in couples undergoing in vitro fertilization procedures: impact on reproductive outcomes. Fertil Steril 2011;95:1845-1848.
25. Rintala MA, Pöllänen PP, Nikkanen VP, Grénman SE, Syrjänen SM. Human papillomavirus DNA is found in the vas deferens. J Infect Dis 2002; 185:1664-1667.
26. Rintala MA, Grénman SE, Pöllänen PP, Suominen JJ, Syrjänen SM. Detection of high-risk HPV DNA in semen and its association with the quality of semen. Int J STD AID 2004;15:740-743.
27. Rogo KO, Nyansera PN. Congenital condylomata acuminata with meconium staining of amniotic fluid and fetal hydrocephalus: case report. East Afr Med J 1989;66:411-413.
28. Stanley M. Pathology and epidemiology of HPV infection in females. Gynecol Oncol 2010;117(2 Suppl.):S5-S10.
29. Svec A, Mikysková I, Hes O, Tachezy R. Human papillomavirus infection of the epididymis and ductus deferens: an evaluation by nested polymerase chain reaction. Arch Pathol Lab Med 2003;127:1471-1474.
30. Tseng CJ, Lin CY, Wang RL, Chen LJ, Chang YL, Hsieh TT, Pao CC. Possible transplacental transmission of human papillomaviruses. Am J Obstet Gynecol 1992;166:35-40.
31. Wang X, Zhu Q, Rao H. Maternal-fetal transmission of human papillomavirus. Chin Med J 1998;111:726-727.
32. Xu S, Liu L, Lu S, Ren S. Clinical observation on vertical transmission of human papillomavirus. Chin Med Sci J 1998;13:29-31.
33. Zimet GD. Potential barriers to HPV immunization: from public health to personal choice. Am J Law Med 2009;35:389-399.