A pilot clinical study on the effectiveness of Mesoglycan against diabetic retinopathy

Clinica Terapeutica

Volumn 163, Issue 1, 2012, Pages 19-22

  Pacella, E ^a   Pacella, F ^a   Turchetti, P ^b   Mazzeo, F ^a   Anzidei, R ^a   Malvasi, A ^a   Malarska, K G ^a   Brillante, C ^a   Gabrieli, C Balacco ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b Italian National Institute of Health   (Italy)

Author keywords

Diabetic retinopathy; Mesoglycan; Retinal vessels

Indexed keywords

MESOGLYCAN; PLACEBO;

ADULT; AGED; ARTICLE; BLEEDING; COMPUTER ASSISTED PERIMETRY; CONTROLLED STUDY; DIABETIC RETINOPATHY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; ELECTRORETINOGRAM; EVOKED VISUAL RESPONSE; EXUDATE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MICROANEURYSM; PILOT STUDY; PRESCRIPTION; RANDOMIZED CONTROLLED TRIAL; RETINA BLOOD VESSEL; RETINA FLUORESCEIN ANGIOGRAPHY; TREATMENT OUTCOME; VISUAL ACUITY; VISUAL FIELD;

AGED; ANEURYSM; DIABETES MELLITUS, TYPE 1; DIABETES MELLITUS, TYPE 2; DIABETIC RETINOPATHY; ENDOTHELIUM, VASCULAR; FEMALE; GLYCOSAMINOGLYCANS; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; MALE; MICROCIRCULATION; MIDDLE AGED; PILOT PROJECTS; RETINAL HEMORRHAGE; TREATMENT OUTCOME; VISUAL ACUITY;

EID: 84858382464     PISSN: 00099074     EISSN: 19726007     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Balacco Gabrieli C, Pacella E. Clinical trials efficacy and tolerability. An esparansolfato (clarema retard) in the treatment of retinopathy arteriosclerotic. Min Oftalmol 1993; 35: 3-7
2. D'Amico D. Diseases of the retina. N Engl J Med 1994; 331: 95-106
3. Wylegała E, Mańkowski W, Pilat J, et al. Diabetic macular edema-modern diagnostics and treatment. Pol Merkur Lekarski 2010; 29(169):61-5
4. Segre G. Pharmacological aspects of glicosammino-glycans. Min Med 1986; 77:1859-64
5. Bettini R, Maino C, Gorini M. Effectiveness of mesoglycan in the prevention of cerebral ischemia. Clin Ter 2003; 154(1): 13-6
6. Hellstedt T, Vesti E, Immonen I. Identification of individual microaneurysms: a comparison between fluorescein angiograms and red-free and colour photographs. Graefes Arch Clin Exp Ophthalmol 1996; 234(Suppl 1):S13-7
7. Krásný J, Cihelková I, Domínek Z, et al. Contrast sensitivity and fluorescein angiography in evaluating the ocular changes in the relation to the diabetes mellitus type I compensation in young adult patients. Cesk Slov Oftalmol 2007; 63(1): 17-27.
8. Nelson EA, Jones J. Venous leg ulcers. Clin Evid (Online). 2008; 15 pii:1902
9. Andreozzi GM. Effectiveness of mesoglycan in patients with previous deep venous thrombosis and chronic venous insufficiency. Minerva Cardioangiol 2007; 55(6):741-53
10. Viliani T, Scarselli M, Pieri A, et al. Pharmacological treatment of mechanical edema: a randomized controlled trial about the effects of mesoglycan. Eur J Phys Rehabil Med 2009; 45(1):21-9
11. Inatani M, Tanihara H. Proteoglycans in retina. Progr Retin Eye Res 2002; 21:429-47
12. Holm K, Ponjavic V, Lövestam-Adrian M. Using multifocal electroretinography hard exudates affect macular function in eyes with diabetic retinopathy. Graefes Arch Clin Exp Ophthalmol 2010; 248(9):1241-7