Reversal of age-related oxidative stress prevents hippocampal synaptic plasticity deficits by protecting d-serine-dependent NMDA receptor activation

Aging Cell

Volumn 11, Issue 2, 2012, Pages 336-344

  Haxaire, Coline ^a   Turpin, Fabrice R ^a,d   Potier, Brigitte ^a   Kervern, Myriam ^a   Sinet, Pierre Marie ^a   Barbanel, Gérard ^b   Mothet, Jean Pierre ^c   Dutar, Patrick ^a   Billard, Jean Marie ^a  

^a CENTRE DE PSYCHIATRIE ET NEUROSCIENCES   (France)

^b UNIVERSITÉ DE MONTPELLIER   (France)

^c AIX MARSEILLE UNIVERSITY   (France)

^d UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Aging; Cognitive impairment; Glutamate receptors; Long term potentiation; N acetylcysteine; Redox status

Indexed keywords

ACETYLCYSTEINE; DEXTRO SERINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; RACEMASE; SERINE RACEMASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN DAMAGE; BRAIN ELECTROPHYSIOLOGY; CELL AGING; CONTROLLED STUDY; DIET SUPPLEMENTATION; HIPPOCAMPAL CA1 REGION; LONG TERM POTENTIATION; MALE; NERVE CELL PLASTICITY; NEUROPROTECTION; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SYNAPTIC POTENTIAL;

ACETYLCYSTEINE; AGING; ANIMALS; HIPPOCAMPUS; LYSINE; MALE; NEURONAL PLASTICITY; OXIDATIVE STRESS; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE; SERINE;

ANIMALIA; RATTUS;

EID: 84858342905     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2012.00792.x     Document Type: Article

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