Synthetic peptide-targeted selection of phage display mimotopes highlights immunogenic features of α-helical vs non-helical epitopes of Taenia solium paramyosin: Implications for parasite- and host-protective roles of the protein

Peptides

Volumn 34, Issue 1, 2012, Pages 232-241

  Gazarian, Karlen G ^a   Solis, Carlos F ^a   Gazarian, Tatiana G ^a,b   Rowley, Merrill ^c   Laclette, Juan P ^a  

^a INSTITUTO DE INVESTIGACIONES BIOMÉDICAS   (Mexico)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^c MONASH UNIVERSITY   (Australia)

Author keywords

Mimotopes; Paramyosin; Peptide; Phage display; Secondary structure prediction; Taenia solium

Indexed keywords

AMINO ACID; EPITOPE; PARAMYOSIN; SYNTHETIC PEPTIDE;

ALPHA HELIX; AMINO ACID SEQUENCE; ANTIBODY RESPONSE; ARTICLE; CONTROLLED STUDY; HOST PARASITE INTERACTION; IMMUNOGENICITY; IMMUNOMODULATION; NONHUMAN; PEPTIDE LIBRARY; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; SEQUENCE ANALYSIS; TAENIA SOLIUM;

ANIMALS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPE MAPPING; EPITOPES; PEPTIDE LIBRARY; PEPTIDES; PROTEIN STRUCTURE, SECONDARY; SWINE; TAENIA SOLIUM; TROPOMYOSIN;

ORYCTOLAGUS CUNICULUS; SUIDAE; TAENIA SOLIUM;

EID: 84858340361     PISSN: 01969781     EISSN: 18735169     Source Type: Journal    
DOI: 10.1016/j.peptides.2011.10.003     Document Type: Article

References (54)

1. C.G. Adda, R.F. Anders, L. Tilley, and M. Foley Random sequence libraries displayed on phage: identification of biologically important molecules Comb Chem High Throughput Screening 5 2002 1 14 (Pubitemid 34292650)
2. E.K. Akpek, S.H. Liu, R. Thompson, and J.D. Gottsch Identification of paramyosin as a binding protein for calgranulin C in experimental helminthic keratitis Invest Ophthalmol Vis Sci 43 2002 2677 2684 (Pubitemid 34809459)
3. A.S. Aluja, A.N.M. Villalobos, A. Plancarte, M. Rodarte, M. Hernández, and E. Sciutto Experimental Taenia solium cysticercosis in pigs: characteristics of the infection and antibody response Vet Parasitol 61 1996 49 59 (Pubitemid 26025843)
4. C. Barton Behravesh, L.F. Mayberry, J.R. Bristol, V.M. Cardenas, K.D. Mena, J. Martinez-Ocana, A. Flisser, and K.F. Snowden Population-based survey of taeniasis along the United States-Mexico border Ann Trop Med Parasitol 102 4 2008 325 333 (Pubitemid 351881275)
5. P.R.M. de Bittencourt, B. Adamolekum, N. Bharucha, A. Carpio, O.H. Cossío, M.A. Danesi, and M. Dumas Epilepsy in the tropics: II. Clinical presentations, pathophysiology, immunologic diagnosis, economics Epilepsia 37 11 1996 1128 1137
6. S. Bryson, J.-Ph. Julien, R.C. Hynes, and E.F. Pai Crystallographic definition of the epitope promiscuity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5: vaccine design implications J Virol 83 2009 11862 11875
7. Y.C.J. Chen, K. Delbrook, C. Dealwis, L. Mimms, K. Mushahwar, and V. Mandecki Discontinuous epitopes of hepatitis B surface antigen derived from a filamentous phage peptide library Proc Natl Acad Sci U S A 93 1996 1997 2001 (Pubitemid 26079870)
8. C. Cohen, and D.A.D. Parry Alpha-helical coiled coils: more facts and better predictions Science 263 5146 1994 488 489 (Pubitemid 24082746)
9. J.M. Davies, M. Scealy, Y-P. Cai, J. Whisstock, I.R. Mackay, and M.J. Rowley Multiple alignments and sorting of peptides derived from phage-displayed random peptide libraries with polyclonal sera allows discrimination of relevant phagotopes Mol Immunol 36 1999 659 667 (Pubitemid 29432129)
10. G. Deleage, and B. Roux DPM. An algorithm for protein secondary structure prediction based on class prediction Protein Eng 1 4 1987 289 294 (Pubitemid 18024006)
11. S. Deroo, and C.P. Muller Antigenic and immunogenic phage displayed mimotopes as substitute antigens: applications and limitations Comb Chem High Throughput Screening 4 2001 75 110 (Pubitemid 32405670)
12. A.J. Doig, C.D. Andrew, D.A. Cochran, E. Huges, S. Penel, J.K. Sun, B.J. Stapley, D.T. Clarke, and G.R. Jones Structure, stability and folding of the alpha-helix Biochem Soc Symp 68 2001 95 110
13. A. Flisser, B. Espinosa, A. Tovar, A. Plancarte, and D. Correa Host-parasite relationship in cysticercosis: immunologic study in different compartments of the host Vet Parasitol 20 1-3 1986 95 102 (Pubitemid 16145022)
14. D. Frishman, and P. Argos PREDATOR. Incorporation of non-local interactions in protein secondary structure prediction from the amino acid sequence Protein Eng 9 2 1996 133 142 (Pubitemid 26119294)
15. Garnier J, Gibrat J-F, Robson B. GOR IV. GOR secondary structure prediction method version IV. In: Doolittle RF (Ed.), Methods in enzymology, vol. 266; 1996. p. 540-53. (Pubitemid 26165888)
16. K. Gazarian Drug discovery and design via high throughput screening of combinatorial phage-display protein-peptide libraries Atta-ur-Rahman Frontiers of drug design and discovery vol. 1 2005 Galdwell Springer, Bentham Science Publisher USA 29 67
17. K.G. Gazarian, T.G. Gazarian, C. Solís, R. Hernández, Ch. Shoemaker, and J.P. Laclette Epitope mapping on Taenia solium paramiyosin N-terminal end Immunol Lett 72 3 2000 191 195 (Pubitemid 30398594)
18. K.G. Gazarian, M.J. Rowley, T.G. Gazarian, J. Sotelo, E. García-Mendoza, and R. Hernández Post-panning computer-aided analysis of phagotope collections selected with neurocysticercosis patient polyclonal antibodies elicited by diverse and as yet unknown antigens: separation of disease-relevant and irrelevant peptide sequences Comb Chem High Throughput Screening 4 3 2001 221 236
19. T.G. Gazarian, B. Selisko, P. Hérion, and K.G. Gazarian Isolation and structure - functional characterization of phage display library-derived mimotopes of noxiustoxin, a neurotoxin of the scorpion Centruroides noxius Hoffmann Mol Immunol 37 2001 12 13 755-66
20. T. Gazarian, B. Selisko, G. Gurrola, R. Hernández, L. Possani, and K. Gazarian Potential of peptides from phage display libraries to mimic conformational epitopes: a study of epitope Cn2 recognized by neutralizing monoclonal antibody BCF2 of scorpion Centruroides noxius Hoffmann Comb Chem High Throughput Screening 6 2003 109 122
21. C. Geourjon, and G. Deleage SOPM. A self-optimized method for protein secondary structure prediction Protein Eng 7 2 1994 157 164 (Pubitemid 24031206)
22. H.M. Geysen, S.Y. Rodda, and T.J. Mason A priori delineation of a peptide which mimics a discontinuous antigenic determinant Mol Immunol 23 1986 709 715 (Pubitemid 16094062)
23. Guermeur Y. HNN. Combinaison de classifieurs statistiques, Application a la prediction de structure secondaire des proteines PhD Thesis; 1997.
24. G. Guerra, A. Flisser, L. Cañedo, and J.P. Laclette F. Willms, J.P. Laclette, C. Larralde, C. Ridaura, F. Beltran, Cysticercosis: Present state of knowledge and Perspectives 1981 Academic Press New York 437 451
25. E. Harlow, and D. Lane Antibodies: a laboratory manual 1988 Cold Spring Laboratory New York
26. U. Hernández-Chiñas, T. Gazarian, K. Gazarian, G. Mendoza-Hernández, J. Xicohtencatl-Cortes, and C. Eslava Peptide sequences identified by phage display are immunodominant functional motifs of Pet and Pic serine proteases secreted by Escherichia coli and Shigella flexneri Peptides 30 2009 2127 2135
27. R.D. King, and M.J. Sternberg DSC. Identification and application of the concepts important for accurate and reliable protein secondary structure prediction Protein Sci 5 11 1996 2298 2310 (Pubitemid 26384468)
28. J.P. Laclette, H. Merchant, and K. Willms Histological and ultrastructural localization of antigen B in the metacestode of Taenia solium J Parasitol 73 1987 12 19
29. J.P. Laclette, A. Alagon, K. Willms, and A. Torre-Blanco Purification of antigen B from Taenia solium cysticerci by affinity to mammalian collagen J Parasitol 76 2 1990 273 275 (Pubitemid 20156054)
30. J.P. Laclette, C.B. Shoemaker, D. Richter, L. Arcos, N. Pante, C. Cohen, D. Bing, and A. Nicholson-Weller Paramyosin inhibits complement C1 J Immunol 148 1 1992 124 128
31. J.P. Laclette, P. Skelly, M. Merchant, and C.B. Shoemaker Aldehyde fixation dramatically alters the immunolocalization pattern of paramyosin in platyhelminth parasites Exp Parasitol 81 1 1995 140 143
32. A. Landa, J.P. Laclette, A. Nicholson-Weller, and C.B. Shoemaker cDNA cloning and recombinant expression of collagen-binding and complement inhibitor activity of Taenia solium paramyosin (AgB) Mol Biochem Parasitol 60 1993 343 347 (Pubitemid 223039714)
33. J.M. Levin, B. Robson, and J. Garnier SIMPA96. An algorithm for secondary structure determination in proteins based on sequence similarity FEBS Lett 205 2 1986 303 308
34. A. Loukas, M.K. Jones, L.T. King, P.J. Brindley, and D.P. McManus Receptor for Fc on the surfaces of schistosomes Infect Immun 69 6 2001 3646 3651 (Pubitemid 32493279)
35. S.M. Lu, and R.S. Hodges A de novo designed template for generating conformation-specific antibodies that recognize alpha-helices in proteins J Biol Chem 277 26 2002 23515 23524 (Pubitemid 34952187)
36. A. Lupas, M.V. Dyke, and J. Stock Predicting coiled coils from protein sequences Science 252 1991 1162 1164 (Pubitemid 21917026)
37. M.C. Manning, M. Illangasekare, and R.W. Woody Circular dichroism studies of distorted alpha-helices, twisted beta-sheets, and beta turns Biophys Chem 31 1988 1 2 77-86
38. Y. Palacios-Rodriguez, T. Gazarian, M. Rowley, A. Mailuf-Cruz, and K. Gazarian Collection of phage-peptide probes for HIV-1 immunodominant loop-epitope J Microbiol Methods 68 2006 225 235 (Pubitemid 46149931)
39. Y. Palacios-Rodriguez, T. Gazarian, L. Huerta, and K. Gazarian Constrained peptide models from phage display libraries highlighting the exclusive epitope specific potential of anti-HIV-1 mAb 2F5 Immunol Lett 136 1 2011 80 89 [Epub 2011 January 13]
40. T.-J. Park, J.-M. Kang, B.-K. Na, and W.-M. Sohn Molecular cloning and characterization of a paramyosin from Clonorchis sinensis Korean J Parasitol 47 4 2009 359 367
41. B. Rost, and C. Sandler Prediction of protein secondary structure at better than 70% accuracy J Mol Biol 232 2 1993 584 599 (Pubitemid 23251181)
42. E. Sciutto, G. Fragoso, A. Fleury, J.P. Laclette, J. Sotelo, A. Aluja, L. Vargas, and C. Larralde Taenia solium disease in humans and pigs: an ancient parasitosis disease rooted in developing countries and emerging as a major health problem of global dimensions Microb Infect 2 15 2000 1875 1890 (Pubitemid 32063541)
43. J.K. Scott, and G.P. Smith Searching for peptide ligands with an epitope library Science 249 1990 386 390
44. G.P. Smith, and J.K. Scott Libraries of peptides and proteins displayed on filamentous phage Methods Enzymol 217 1993 228 257
45. T.A. Smith, P.D. Hempstead, C.C. Palliser, and D.A.D. Parry Modeling alpha-helical coiled-coil interactions: the axial and azimuthal alignment of 1B segments from vimentin intermediate filaments Protein Struct Funct Genet 50 2 2003 207 212 (Pubitemid 36055599)
46. C.F. Solís, P. Ostoa-Saloma, V.H. Lugo-Martínez, S.A. Johnston, and J.P. Laclette Genetic vaccination against murine cysticercosis by using a plasmid vector carrying Taenia solium paramyosin Infect Immun 73 3 2005 1895 1897 (Pubitemid 40470784)
47. Stephen ChW, P. Helminen, and D.P. Lane Characterization of epitopes on human p53 using phage-displayed peptide libraries: insight into antibody-peptide interactions J Mol Biol 248 1995 58 78
48. B. Stern, G. Denisova, D. Buyaner, D. Raviv, and J.M. Gershoni Helical epitopes determined by low-stringency antibody screening of a combinatorial peptide library FASEB J 11 1997 147 153 (Pubitemid 27097588)
49. R. Sundaram, M.P. Lynch, S.V. Rawale, Y. Sun, M. Kazanii, and P.T. Kaumava De novo design of peptide immunogens that mimic the coiled coil region of human T-cell leukemia virus type-1 glycoprotein 21 transmembrane subunit for induction of native protein reactive neutralizing antibodies J Biol Chem 279 23 2004 24141 24151 (Pubitemid 38725274)
50. H. Towbin, T. Staehelin, and J. Gordon Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets. Procedure and some applications Proc Natl Acad Sci U S A 76 1979 4350 4354 (Pubitemid 9256559)
51. P.J. Tighe, A. Pawell-Richards, H.F. Sewell, D. Fisher, L. Donoso, and H.S. Dua Epitope discovery using bacteriophage display: the minimum epitope of an anti-IRBP antibody Exp Eye Res 68 6 1998 679 684 (Pubitemid 29290787)
52. J. Vazquez-Talavera, C.F. Solis, L.I. Terrazas, and J.P. Laclette Characterization and protective potential of the immune response to Taenia solium paramyosin in a murine model of cysticercosis Infect Immun 69 2001 5412 5416 (Pubitemid 32786473)
53. A.S. Winkler, J. Blocher, H. Auer, T. Gotwald, W. Matuja, and E. Schmutzhard Epilepsy and neurocysticercosis in rural Tanzania - an imaging study Epilepsia 5 2009 987 993
54. I. Zelezetskyn, and A. Tossi Alpha-helical antimicrobial peptides - using a sequence to guide structure-activity relationship studies Biochim Biophys Acta 1758 2006 1436 1449 (Pubitemid 44436080)