In vivo confocal microscopic features of normal limbus

British Journal of Ophthalmology

Volumn 96, Issue 4, 2012, Pages 530-536

  Miri, Ammar ^a,b   Al Aqaba, Muhamed ^a   Otri, Ahmad Muneer ^a,b   Fares, Usama ^a   Said, Dalia G ^a,c   Faraj, Lana Akram ^a   Dua, Harminder S ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b UNIVERSITY OF ALEPPO   (Syrian Arab Republic)

^c RESEARCH INSTITUTE OF OPHTHALMOLOGY   (Egypt)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ANATOMICAL CONCEPTS; ANATOMICAL VARIATION; ARTICLE; CELL DENSITY; CELL SIZE; CELL STRUCTURE; CONFOCAL MICROSCOPY; CONJUNCTIVA EPITHELIUM; CONTROLLED STUDY; CORNEA CELL; CORNEA LIMBUS; CRYPT CELL; EPITHELIUM CELL; FEMALE; HISTOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMAGE ANALYSIS; IMAGE DISPLAY; IN VIVO STUDY; INTERMETHOD COMPARISON; MALE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS;

ADULT; CELL COUNT; CELL SIZE; EPITHELIUM, CORNEAL; FEMALE; HUMANS; LIMBUS CORNEAE; MALE; MICROSCOPY, CONFOCAL; MIDDLE AGED; PIGMENTATION; REFERENCE VALUES; REPRODUCIBILITY OF RESULTS; YOUNG ADULT;

EID: 84858339259     PISSN: 00071161     EISSN: 14682079     Source Type: Journal    
DOI: 10.1136/bjophthalmol-2011-300550     Document Type: Article

References (21)

1. Patel DV, Sherwin T, McGhee CN. Laser scanning in vivo confocal microscopy of the normal human corneoscleral limbus. Invest Ophthalmol Vis Sci 2006;47:2823-7. (Pubitemid 351639753)
2. Dua HS, Kulkarni B, Singh R. Quest for limbal stem cells. Clin Experiment Ophthalmol 2006;34:1-2. (Pubitemid 43379361)
3. Dua HS, Shanmuganathan VA, Powell-Richards AO, et al. Limbal epithelial crypts: a novel anatomical structure and a putative limbal stem cell niche. Br J Ophthalmol 2005;89:529-32. (Pubitemid 40569702)
4. Shanmuganathan VA, Foster T, Kulkarni BB, et al. Morphological characteristics of the limbal epithelial crypt. Br J Ophthalmol 2007;91:514-19. (Pubitemid 46623688)
5. Yeung AM, Schlotzer-Schrehardt U, Kulkarni B, et al. Limbal epithelial crypt: a model for corneal epithelial maintenance and novel limbal regional variations. Arch Ophthalmol 2008;126:665-9. (Pubitemid 351679562)
6. Goldberg MF, Bron AJ. Limbal palisades of Vogt. Trans Am Ophthalmol Soc 1982;80:155-71.
7. WM T. The limbal palisades of Vogt. Trans Am Ophthalmol Soc 1991;89:721-56.
8. Kulkarni BB, Tighe PJ, Mohammed I, et al. Comparative transcriptional profiling of the limbal epithelial crypt demonstrates its putative stem cell niche characteristics. BMC Genomics 2010;11:526.
9. Perez-Gomez I, Hollingsworth J, Efron N. Effects of benoxinate hydrochloride 0.4% on the morphological appearance of the cornea using confocal microscopy. Cont Lens Anterior Eye 2004;27:45-8. (Pubitemid 38240370)
10. Miri A, Said DG, Dua HS. Donor site complications in autolimbal and living-related allolimbal transplantation. Ophthalmology 2011;118:1265-71.
11. Guthoff RF, Baudouin C, Stave J. Atlas of confocal laser scanning in-vivo microscopy in Ophthalmology. Berlin: Springer, 2006:31-52.
12. Townsend WM. The limbal palisades of Vogt. Trans Am Ophthalmol Soc 1991;89:721-56.
13. Espana EM, Romano AC, Kawakita T, et al. Novel enzymatic isolation of an entire viable human limbal epithelial sheet. Invest Ophthalmol Vis Sci 2003;44:4275-81. (Pubitemid 37186261)
14. Cotsarelis G, Cheng SZ, Dong G, et al. Existence of slow-cycling limbal epithelial basal cells that can be preferentially stimulated to proliferate: implications on epithelial stem cells. Cell 1989;57:201-9. (Pubitemid 19112360)
15. Zheng TY, Zhang Y, Xu JJ, et al. [Proliferative ability and ultramicrostructure of basal limbal epithelial cells in different age group of normal subjects]. Zhonghua Yan Ke Za Zhi 2009;45:799-804.
16. Rong B, Yan XM. [In vivo study of normal human limbal and central corneas using laser confocal microscope]. Zhonghua Yan Ke Za Zhi 2006;42:17-21.
17. Nubile M, Dua HS, Lanzini TE, et al. Amniotic membrane transplantation for the management of corneal epithelial defects: an in vivo confocal microscopic study. Br J Ophthalmol 2008;92:54-60.
18. Takahashi N, Chikama T, Yanai R, et al. Structures of the corneal limbus detected by laser-scanning confocal biomicroscopy as related to the palisades of Vogt detected by slit-lamp microscopy. Jpn J Ophthalmol 2009;53:199-203.
19. Kobayashi A, Sugiyama K. In vivo corneal confocal microscopic findings of palisades of Vogt and its underlying limbal stroma. Cornea 2005;24:435-7. (Pubitemid 40586633)
20. Romano AC, Espana EM, Yoo SH, et al. Different cell sizes in human limbal and central corneal basal epithelia measured by confocal microscopy and flow cytometry. Invest Ophthalmol Vis Sci 2003;44:5125-9. (Pubitemid 37475379)
21. Jester JV, Petroll WM, Feng W, et al. Radial keratotomy. 1. The wound healing process and measurement of incisional gape in two animal models using in vivo confocal microscopy. Invest Ophthalmol Vis Sci 1992;33:3255-70.