Statin therapy for subclinical atherosclerosis in primary prevention: Time to prove it?

JACC: Cardiovascular Imaging

Volumn 5, Issue 3, 2012, Pages 261-263

  Villines, Todd C ^a,b  

^a WALTER REED ARMY MEDICAL CENTER   (United States)

^b UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

coronary artery calcification; family history; primary prevention; statins

Indexed keywords

ACETYLSALICYLIC ACID; ATORVASTATIN;

CARDIOVASCULAR RISK; CORONARY ARTERY ATHEROSCLEROSIS; FAMILY HISTORY; HEART INFARCTION; HEART MUSCLE REVASCULARIZATION; HUMAN; ISCHEMIC HEART DISEASE; NOTE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); RISK ASSESSMENT;

EID: 84858328061     PISSN: 1936878X     EISSN: 18767591     Source Type: Journal    
DOI: 10.1016/j.jcmg.2011.11.015     Document Type: Editorial

References (13)

1. G. Sangiorgi, J.A. Rumberger, A. Severson Arterial calcification and not lumen stenosis is highly correlated with atherosclerotic plaque burden in humans: a histologic study of 723 coronary artery segments using nondecalcifying methodology J Am Coll Cardiol 31 1998 126 133 (Pubitemid 28064732)
2. T.S. Polonsky, R.L. McClelland, N.W. Jorgensen Coronary artery calcium score and risk classification for coronary heart disease prediction JAMA 303 2010 1610 1616
3. Y. Arad, L.A. Spadaro, M. Roth, D. Newstein, A.D. Guerci Treatment of asymptomatic adults with elevated coronary calcium scores with atorvastatin, vitamin C, and vitamin E: the St Francis Heart Study randomized clinical trial J Am Coll Cardiol 46 2005 166 172 (Pubitemid 40905146)
4. M.J. Blaha, M.J. Budoff, A.P. DeFilippis Associations between C-reactive protein, coronary artery calcium, and cardiovascular events: implications for the JUPITER population from MESA, a population-based cohort study Lancet 378 2011 684 692
5. P. Greenland, J.S. Alpert, G.A. Beller 2010 ACCF/AHA guideline for assessment of cardiovascular risk in asymptomatic adults: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines J Am Coll Cardiol 56 2010 2182 2199
6. A.J. Taylor, M. Cerqueira, J.M. Hodgson et al. ACCF/SCCT/ACR/AHA/ASE/ ASNC/NASCI/SCAI/SCMR 2010 appropriate use criteria for cardiac computed tomography A report of the American College of Cardiology Foundation Appropriate Use Criteria Task Force, the Society of Cardiovascular Computed Tomography, the American College of Radiology, the American Heart Association, the American Society of Echocardiography, the American Society of Nuclear Cardiology, the North American Society for Cardiovascular Imaging, the Society for Cardiovascular Angiography and Interventions, and the Society for Cardiovascular Magnetic Resonance J Am Coll Cardiol 56 2010 1864 1894
7. A. Rozanski, H. Gransar, L.J. Shaw Impact of coronary artery calcium scanning on coronary risk factors and downstream testing the EISNER (Early Identification of Subclinical Atherosclerosis by Noninvasive Imaging Research) prospective randomized trial J Am Coll Cardiol 57 2011 1622 1632
8. A.J. Taylor, J. Bindeman, I. Feuerstein Community-based provision of statin and aspirin after the detection of coronary artery calcium within a community-based screening cohort J Am Coll Cardiol 51 2008 1337 1341 (Pubitemid 351454042)
9. K. Nasir, M.J. Budoff, W.S. Post Electron beam CT versus helical CT scans for assessing coronary calcification: current utility and future directions Am Heart J 146 2003 969 977 (Pubitemid 37500769)
10. T.A. Mulders, S. Sivapalaratnam, E.S.G. Stroes, J.J.P. Kastelein, A.D. Guerci, S.J. Pinto-Sietsma Asymptomatic individuals with a positive family history for premature coronary artery disease and elevated coronary calcium scores benefit from statin treatment: a post hoc analysis from the St. Francis Heart Study J Am Coll Cardiol Img 5 2012 252 260
11. R.R. Williams, S.C. Hunt, G. Heiss Usefulness of cardiovascular family history data for population-based preventive medicine and medical research (the Health Family Tree Study and the NHLBI Family Heart Study) Am J Cardiol 87 2001 129 135 (Pubitemid 32057219)
12. F. Taylor, K. Ward, T.H.M. Moore Statins for the primary prevention of cardiovascular disease Cochrane Database of Syst Rev 1 2011 CD004816
13. K.K. Ray, S.R. Seshasai, S. Erqou Statins and all-cause mortality in high-risk primary prevention: a meta-analysis of 11 randomized controlled trials involving 65,229 participants Arch Intern Med 170 2010 1024 1031