An angiotensin II type 1 receptor blocker prevents renal injury via inhibition of the notch pathway in Ins2 akita diabetic mice

Experimental Diabetes Research

Volumn 2012, Issue , 2012, Pages

  Koshizaka, Masaya ^a   Takemoto, Minoru ^b   Sato, Seiya ^c   Tokuyama, Hirotake ^a   Fujimoto, Masaki ^b   Okabe, Emiko ^a   Ishibashi, Ryoichi ^a   Ishikawa, Takahiro ^a   Tsurutani, Yuya ^a   Onishi, Shunichiro ^a   Mezawa, Morito ^a   He, Peng ^a   Honjo, Satoshi ^a   Ueda, Shiro ^d   Saito, Yasushi ^a   Yokote, Koutaro ^a  

^a CHIBA UNIVERSITY   (Japan)

^b CHIBA UNIVERSITY HOSPITAL   (Japan)

^c Seiwa Narashino   (Japan)

^d Ueda Clinic   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

JAGGED1; NOTCH1 RECEPTOR; RECOMBINANT TRANSFORMING GROWTH FACTOR BETA; RECOMBINANT VASCULOTROPIN; TELMISARTAN; TRANSFORMING GROWTH FACTOR BETA; VASCULOTROPIN A; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; BENZIMIDAZOLE DERIVATIVE; BENZOIC ACID DERIVATIVE; CALCIUM BINDING PROTEIN; MEMBRANE PROTEIN; NOTCH1 PROTEIN, MOUSE; SERRATE PROTEINS; SIGNAL PEPTIDE; VASCULAR ENDOTHELIAL GROWTH FACTOR A, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DRUG EFFICACY; DRUG INHIBITION; EXPERIMENTAL MOUSE; GLOMERULUS; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NONHUMAN; PODOCYTE; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TREATMENT OUTCOME; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; DIABETES MELLITUS; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; PATHOLOGY;

ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; BENZIMIDAZOLES; BENZOATES; CALCIUM-BINDING PROTEINS; CELLS, CULTURED; DIABETES MELLITUS; DIABETIC NEPHROPATHIES; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; KIDNEY GLOMERULUS; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; RECEPTOR, NOTCH1; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84858326777     PISSN: 16875214     EISSN: 16875303     Source Type: Journal    
DOI: 10.1155/2012/159874     Document Type: Article

References (20)

1. Wild S., Roglic G., Green A., Sicree R., King H., Global prevalence of diabetes: estimates for the year 2000 and projections for 2030 Diabetes Care 2004 27 5 1047 1053 (Pubitemid 38579764)
2. Ritz E., Rychlik I., Locatelli F., Halimi S., End-stage renal failure in type 2 diabetes: a medical catastrophe of worldwide dimensions American Journal of Kidney Diseases 1999 34 5 795 808 (Pubitemid 29521694)
3. Meier M., Menne J., Haller H., Targeting the protein kinase C family in the diabetic kidney: lessons from analysis of mutant mice Diabetologia 2009 52 5 765 775
4. Dunlop M., Aldose reductase and the role of the polyol pathway in diabetic nephropathy Kidney International 2000 58 77, supplement S3 S12
5. Yamamoto H., Watanabe T., Yamamoto Y., Yonekura H., Munesue S., Harashima A., Ooe K., Hossain S., Saito H., Murakami N., RAGE in diabetic nephropathy Current Molecular Medicine 2007 7 8 752 757
6. Gurley S. B., Coffman T. M., The renin-angiotensin system and diabetic nephropathy Seminars in Nephrology 2007 27 2 144 152 (Pubitemid 46550312)
7. Yusuf S., Teo K. K., Pogue J., Dyal L., Copland I., Schumacher H., Dagenais G., Sleight P., Anderson C., Telmisartan, ramipril, or both in patients at high risk for vascular events New England Journal of Medicine 2008 358 15 1547 1559 (Pubitemid 351522739)
8. Niranjan T., Bielesz B., Gruenwald A., Ponda M. P., Kopp J. B., Thomas D. B., Susztak K., The Notch pathway in podocytes plays a role in the development of glomerular disease Nature Medicine 2008 14 3 290 298 (Pubitemid 351347919)
9. Artavanis-Tsakonas S., Rand M. D., Lake R. J., Notch signaling: cell fate control and signal integration in development Science 1999 284 5415 770 776 (Pubitemid 29291335)
10. Egan S. E., St-Pierre B., Leow C. C., Notch receptors, partners and regulators: from conserved domains to powerful functions Current Topics in Microbiology and Immunology 1998 228 273 324 (Pubitemid 27504965)
11. Mundel P., Reiser J., Kriz W., Induction of differentiation in cultured rat and human podocytes Journal of the American Society of Nephrology 1997 8 5 697 705 (Pubitemid 27493583)
12. Hellstrm M., Phng L. K., Gerhardt H., VEGF and Notch signaling: the yin and yang of angiogenic sprouting Cell Adhesion amp; Migration 2007 1 3 133 136
13. Durvasula R. V., Shankland S. J., Activation of a local renin angiotensin system in podocytes by glucose American Journal of Physiology 2008 294 4 F830 F839
14. Ly J., Alexander M., Quaggin S. E., A podocentric view of nephrology Current Opinion in Nephrology and Hypertension 2004 13 3 299 305 (Pubitemid 38584614)
15. Kintscher U., Foryst-Ludwig A., Unger T., Inhibiting angiotensin type 1 receptors as a target for diabetes Expert Opinion on Therapeutic Targets 2008 12 10 1257 1263
16. Ando H., Zhou J., Macova M., Imboden H., Saavedra J. M., Angiotensin II AT1 receptor blockade reverses pathological hypertrophy and inflammation in brain microvessels of spontaneously hypertensive rats Stroke 2004 35 7 1726 1731 (Pubitemid 38823655)
17. Tien A. C., Rajan A., Bellen H. J., A notch updated Journal of Cell Biology 2009 184 5 621 629
18. Lin C. L., Wang F. S., Hsu Y. C., Chen G. N., Tseng M. J., Saleem M. A., Chang P. J., Wang J. Y., Modulation of Notch-1 signaling alleviates vascular endothelial growth factor-mediated diabetic nephropathy Diabetes 2010 59 8 1915 1925
19. Tomita T., Secretase inhibitors and modulators for Alzheimer's disease treatment Expert Review of Neurotherapeutics 2009 9 5 661 679
20. Inoue T., Node K., Telmisartan as a metabolic sartan for targeting vascular failure Expert Opinion on Pharmacotherapy 2008 9 8 1397 1406 (Pubitemid 351877522)