Hypoxia in early life is associated with lasting changes in left ventricular structure and function at maturity in the rat

International Journal of Cardiology

Volumn 156, Issue 2, 2012, Pages 165-173

  Del Duca, Danny ^a   Tadevosyan, Artavazd ^b,c   Karbassi, Farhad ^d   Akhavein, Farhad ^a   Vaniotis, George ^b,c   Rodaros, Demetra ^a   Villeneuve, Louis R ^c   Allen, Bruce G ^b,c   Nattel, Stanley ^b,c,d   Rohlicek, Charles V ^a,d   Hébert, Terence E ^d  

^a MONTREAL CHILDREN S HOSPITAL   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c MONTREAL HEART INSTITUTE   (Canada)

^d MCGILL UNIVERSITY   (Canada)

Author keywords

Congenital heart disease; Neonatal hypoxia; Ventricular function; Ventricular structure

Indexed keywords

HEXOKINASE; HEXOKINASE 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL WALL THICKNESS; ARTERIOLE; ARTICLE; ATROPHY; BLOOD VESSEL DIAMETER; CALCIUM CELL LEVEL; CELL ATROPHY; CELL STRUCTURE; CELL VIABILITY; CELL VOLUME; CELLULAR DISTRIBUTION; CONGENITAL HEART DISEASE; CONTROLLED STUDY; DIASTOLIC DYSFUNCTION; DISEASE ASSOCIATION; ENZYME ACTIVITY; HEART DEVELOPMENT; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE HYPERTROPHY; HEART MUSCLE; HEART MUSCLE CELL; HISTOPATHOLOGY; HYPOXIA; MALE; MORPHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; RISK ASSESSMENT; STRUCTURE ANALYSIS; TISSUE DISTRIBUTION; TRANSTHORACIC ECHOCARDIOGRAPHY;

AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; ANOXIA; FEMALE; HYPERTROPHY, LEFT VENTRICULAR; MALE; RATS; RATS, SPRAGUE-DAWLEY; VENTRICULAR FUNCTION, LEFT; VENTRICULAR REMODELING;

EID: 84858288199     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2010.10.135     Document Type: Article

References (43)

1. A.J. Marelli, A.S. Mackie, R. Ionescu-Ittu, E. Rahme, and L. Pilote Congenital heart disease in the general population: changing prevalence and age distribution Circulation 115 2007 163 172 (Pubitemid 46105714)
2. A. Gratz, J. Hess, and A. Hager Self-estimated physical functioning poorly predicts actual exercise capacity in adolescents and adults with congenital heart disease Eur Heart J 30 2009 497 504
3. O. Trojnarska, A. Gwizdala, S. Katarzynski, A. Katarzynska, and A. Szyszka Evaluation of exercise capacity with cardiopulmonary exercise test and B-type natriuretic peptide in adults with congenital heart disease Cardiol J 16 2009 133 141
4. G. Vaksmann, A. Fournier, A. Davignon, G. Ducharme, and L. Houyel Frequency and prognosis of arrhythmias after operative "correction" of tetralogy of Fallot Am J Cardiol 66 1990 346 349 (Pubitemid 20235761)
5. O. Trojnarska, S. Grajek, L. Kramer, and A. Gwizdala Risk factors of supraventricular arrhythmia in adults with congenital heart disease Cardiol J 16 2009 218 226
6. E.N. Oechslin, D.A. Harrison, M.S. Connelly, G.D. Webb, and S.C. Siu Mode of death in adults with congenital heart disease Am J Cardiol 86 2000 1111 1116
7. J.L. Monro, C. Alexiou, A.P. Salmon, and B.R. Keeton Reoperations and survival after primary repair of congenital heart defects in children J Thorac Cardiovasc Surg 126 2003 511 520 (Pubitemid 37048520)
8. H.P. Nieminen, E.V. Jokinen, and H.I. Sairanen Late results of pediatric cardiac surgery in Finland: a population-based study with 96% follow-up Circulation 104 2001 570 575 (Pubitemid 32738127)
9. P.A. Berdat, F. Immer, J.P. Pfammatter, and T. Carrel Reoperations in adults with congenital heart disease: analysis of early outcome Int J Cardiol 93 2004 239 245 (Pubitemid 38229593)
10. S.K. Srinathan, R.S. Bonser, B. Sethia, S.A. Thorne, and W.J. Brawn Changing practice of cardiac surgery in adult patients with congenital heart disease Heart 91 2005 207 212
11. Padalino MA, Speggiorin S, Rizzoli G, Crupi G, Vida VL, et al. (2007) Midterm results of surgical intervention for congenital heart disease in adults: an Italian multicenter study. J Thorac Cardiovasc Surg 134: 106-113, 113 e101-109.
12. G.L. Abarbanell, C.S. Goldberg, E.J. Devaney, R.G. Ohye, and E.L. Bove Early surgical morbidity and mortality in adults with congenital heart disease: the University of Michigan experience Congenit Heart Dis 3 2008 82 89 (Pubitemid 351467910)
13. A. Giamberti, M. Chessa, R. Abella, G. Butera, and C. Carlucci Morbidity and mortality risk factors in adults with congenital heart disease undergoing cardiac reoperations Ann Thorac Surg 88 2009 1284 1289
14. C.V. Rohlicek, S. Viau, P. Trieu, and T.E. Hebert Effects of neonatal hypoxia in the rat on inotropic stimulation of the adult heart Cardiovasc Res 65 2005 861 868 (Pubitemid 40249730)
15. Del Duca D, Wong G, Trieu P, Rodaros D, Kouremenos A, et al. (2009) Association of neonatal hypoxia with lasting changes in left ventricular gene expression: an animal model. J Thorac Cardiovasc Surg 138: 538-546, 546 e531.
16. X.Y. Qi, Y.H. Yeh, L. Xiao, B. Burstein, and A. Maguy Cellular signaling underlying atrial tachycardia remodeling of L-type calcium current Circ Res 103 2008 845 854
17. P. Coutu, D. Chartier, and S. Nattel Comparison of Ca2+-handling properties of canine pulmonary vein and left atrial cardiomyocytes Am J Physiol Heart Circ Physiol 291 2006 H2290 2300
18. Y.H. Yeh, R. Wakili, X.Y. Qi, D. Chartier, and P. Boknik Calcium-handling abnormalities underlying atrial arrhythmogenesis and contractile dysfunction in dogs with congestive heart failure Circ Arrhythm Electrophysiol 1 2008 93 102
19. J. Naghshin, K.R. McGaffin, W.G. Witham, M.A. Mathier, and L.C. Romano Chronic intermittent hypoxia increases left ventricular contractility in C57BL/6 J mice J Appl Physiol 107 2009 787 793
20. F. Akhavein, E.J. St-Michel, E. Seifert, and C.V. Rohlicek Decreased left ventricular function, myocarditis, and coronary arteriolar medial thickening following monocrotaline administration in adult rats J Appl Physiol 103 2007 287 295 (Pubitemid 47092303)
21. E. Gurel, K.M. Smeele, O. Eerbeek, A. Koeman, and C. Demirci Ischemic preconditioning affects hexokinase activity and HKII in different subcellular compartments throughout cardiac ischemia-reperfusion J Appl Physiol 106 2009 1909 1916
22. N. Majewski, V. Nogueira, R.B. Robey, and N. Hay Akt inhibits apoptosis downstream of BID cleavage via a glucose-dependent mechanism involving mitochondrial hexokinases Mol Cell Biol 24 2004 730 740 (Pubitemid 38057924)
23. K.R. Stenmark, K.A. Fagan, and M.G. Frid Hypoxia-induced pulmonary vascular remodeling: cellular and molecular mechanisms Circ Res 99 2006 675 691 (Pubitemid 44498302)
24. I.M. Keith, A.L.S. Tjen, H. Kraiczi, and R. Ekman Three-week neonatal hypoxia reduces blood CGRP and causes persistent pulmonary hypertension in rats Am J Physiol Heart Circ Physiol 279 2000 H1571 1578
25. V.R. Fernandes, J.F. Polak, S. Cheng, B.D. Rosen, and B. Carvalho Arterial stiffness is associated with regional ventricular systolic and diastolic dysfunction: the multi-ethnic study of atherosclerosis Arterioscler Thromb Vasc Biol 28 2008 194 201
26. V. Vaccarino, T.R. Holford, and H.M. Krumholz Pulse pressure and risk for myocardial infarction and heart failure in the elderly J Am Coll Cardiol 36 2000 130 138 (Pubitemid 30466123)
27. R.B. Robey, and N. Hay Mitochondrial hexokinases: guardians of the mitochondria Cell Cycle 4 2005 654 658 (Pubitemid 41353844)
28. S. Tandan, Y. Wang, T.T. Wang, N. Jiang, and D.D. Hall Physical and functional interaction between calcineurin and the cardiac L-type Ca2+ channel Circ Res 105 2009 51 60
29. B. Swynghedauw Molecular mechanisms of myocardial remodeling Physiol Rev 79 1999 215 262 (Pubitemid 29056953)
30. M.F. Allard Energy substrate metabolism in cardiac hypertrophy Curr Hypertens Rep 6 2004 430 435 (Pubitemid 39600098)
31. A.D. Pichard, H. Smith, J. Holt, J. Meller, and R. Gorlin Coronary vascular reserve in left ventricular hypertrophy secondary to chronic aortic regurgitation Am J Cardiol 51 1983 315 320 (Pubitemid 13179403)
32. Gaasch W.H., Zile M.R., Hoshino P.K., Weinberg E.O., and Rhodes D.R. Tolerance of the hypertrophic heart to ischemia. Studies in compensated and failing dog hearts with pressure overload hypertrophy Circulation 81 1990 1644 1653 (Pubitemid 20158303)
33. J. Grewal, R.B. McCully, G.C. Kane, C. Lam, and P.A. Pellikka Left ventricular function and exercise capacity JAMA 301 2009 286 294
34. P.J. Oldershaw, K.D. Dawkins, D.E. Ward, and D.G. Gibson Diastolic mechanisms of impaired exercise tolerance in aortic valve disease Br Heart J 49 1983 568 573 (Pubitemid 13106241)
35. S.E. Lipshultz, E.J. Orav, S.P. Sanders, K. McIntosh, and S.D. Colan Limitations of fractional shortening as an index of contractility in pediatric patients infected with human immunodeficiency virus J Pediatr 125 1994 563 570 (Pubitemid 24318426)
36. Mentzer R.M. Jr., Jahania M.S., and Lasley R.D. Myocardial protection Cohn L.H. Cardiac surgery in the adult 3rd ed 2008 McGraw-Hill New York 443 463
37. M.J. Daly, J.S. Elz, and W.G. Nayler Contracture and the calcium paradox in the rat heart Circ Res 61 1987 560 569 (Pubitemid 17134965)
38. M. Hartford, J.C. Wikstrand, I. Wallentin, S.M. Ljungman, and G.L. Berglund Left ventricular wall stress and systolic function in untreated primary hypertension Hypertension 7 1985 97 104 (Pubitemid 15117146)
39. Ross B, McIntosh M, Rodaros D, Hebert TE, Rohlicek CV (2010) systemic arterial pressure at maturity in rats following chronic hypoxia in early life. Am J Hypertens. 2010;23:1228-33.
40. K.A. Webster, P. Gunning, E. Hardeman, D.C. Wallace, and L. Kedes Coordinate reciprocal trends in glycolytic and mitochondrial transcript accumulations during the in vitro differentiation of human myoblasts J Cell Physiol 142 1990 566 573
41. G. Ye, R.V. Donthi, N.S. Metreveli, and P.N. Epstein Overexpression of hexokinase protects hypoxic and diabetic cardiomyocytes by increasing ATP generation Cardiovasc Toxicol 5 2005 293 300 (Pubitemid 41506870)
42. R.B. Robey, and N. Hay Mitochondrial hexokinases, novel mediators of the antiapoptotic effects of growth factors and Akt Oncogene 25 2006 4683 4696 (Pubitemid 44187618)
43. A.J. Coats Ethical authorship and publishing Int J Cardiol 131 2009 149 150