Effects of telmisartan on C-reactive protein levels: A meta-analysis of randomized controlled trials

International Journal of Cardiology

Volumn 156, Issue 2, 2012, Pages 238-241

  Takagi, Hisato ^a   Yamamoto, Hirotaka ^a   Iwata, Kotaro ^a   Goto, Shin Nosuke ^a   Umemoto, Takuya ^a  

^a SHIZUOKA MEDICAL CENTER   (Japan)

Author keywords

C reactive protein; Meta analysis; Randomized controlled trial; Telmisartan

Indexed keywords

ADIPONECTIN; ATORVASTATIN; C REACTIVE PROTEIN; CANDESARTAN; ENALAPRIL; IRBESARTAN; LOSARTAN; OLMESARTAN; RAMIPRIL; ROSUVASTATIN; TELMISARTAN; VALSARTAN;

COCHRANE LIBRARY; DRUG EFFECT; EMBASE; HUMAN; HYPERTENSION; INFORMATION RETRIEVAL; LETTER; MEDLINE; META ANALYSIS; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); STATISTICAL ANALYSIS;

EID: 84858286193     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2012.01.104     Document Type: Article

References (35)

1. K. Prasad C-reactive protein (CRP)-lowering agents Cardiovasc Drug Rev 24 2006 33 50 (Pubitemid 46722293)
2. T. Yoshida, S. Yamagishi, and K. Nakamura Telmisartan inhibits AGE-induced C-reactive protein production through downregulation of the receptor for AGE via peroxisome proliferator-activated receptor-gamma activation Diabetologia 49 2006 3094 3099 (Pubitemid 44730314)
3. B.R. Goyal, P. Mesariya, R.K. Goyal, and A.A. Mehta Effect of telmisartan on cardiovascular complications associated with streptozotocin diabetic rats Mol Cell Biochem 314 2008 123 131
4. X. Xu, X. Yin, W. Feng, G. Li, D. Wang, and L. Tu Telmisartan protects against insulin resistance by attenuating inflammatory response in rats J Huazhong Univ Sci Technolog Med Sci 31 2011 317 323
5. T. Wago, T. Yoshimoto, and I. Akaza Improvement of endothelial function in patients with hypertension and type 2 diabetes after treatment with telmisartan Hypertens Res 33 2010 796 801
6. Higgins JP, Deeks JJ, Altman DG, editors. Chapter 16: Special topics in statistics. In: Higgins JP, Green S, editors. Cochrane Handbook for Systematic Reviews of Interventions. Version 5.1.0 (updated March 2011). The Cochrane Collaboration; 2011. Available from www.cochrane-handbook.org.
7. D. Follmann, P. Elliott, I. Suh, and J. Cutler Variance imputation for overviews of clinical trials with continuous response J Clin Epidemiol 45 1992 769 773
8. G. Bakris, E. Burgess, M. Weir, G. Davidai, S. Koval, and AMADEO Study Investigators Telmisartan is more effective than losartan in reducing proteinuria in patients with diabetic nephropathy Kidney Int 74 2008 364 369 (Pubitemid 352002795)
9. Olmesartan medoxomil is associated with decreased plasma AGEs pentosidine, and N-(epsilon)-carboxymethyl-lysine levels in hemodialysis patients Clin Exp Hypertens 34 2012 17 23
10. S.J. Hong, W.J. Shim, and J.I. Choi Comparison of effects of telmisartan and valsartan on late lumen loss and inflammatory markers after sirolimus-eluting stent implantation in hypertensive patients Am J Cardiol 100 2007 1625 1629 (Pubitemid 350122328)
11. S.J. Hong, S.C. Choi, C.M. Ahn, J.H. Park, J.S. Kim, and D.S. Lim Telmisartan reduces neointima volume and pulse wave velocity 8 months after zotarolimus-eluting stent implantation in hypertensive type 2 diabetic patients Heart 97 2011 1425 1432
12. S. Koulouris, P. Symeonides, and K. Triantafyllou Comparison of the effects of ramipril versus telmisartan in reducing serum levels of high-sensitivity C-reactive protein and oxidized low-density lipoprotein cholesterol in patients with type 2 diabetes mellitus Am J Cardiol 95 2005 1386 1388 (Pubitemid 40719878)
13. S. Makita, A. Abiko, Y. Naganuma, Y. Moriai, and M. Nakamura Effects of telmisartan on adiponectin levels and body weight in hypertensive patients with glucose intolerance Metabolism 57 2008 1473 1478
14. N. Ozaki, Y. Nomura, H. Sobajima, K. Kondo, and Y. Oiso Comparison of the effects of three angiotensin II receptor type 1 blockers on metabolic parameters in hypertensive patients with type 2 diabetes mellitus Eur J Intern Med 21 2010 236 239
15. I. Porto, L. Di Vito, and G.L. De Maria Comparison of the effects of ramipril versus telmisartan on high-sensitivity C-reactive protein and endothelial progenitor cells after acute coronary syndrome Am J Cardiol 103 2009 1500 1505
16. C.V. Rizos, H.J. Milionis, and M.S. Kostapanos Effects of rosuvastatin combined with olmesartan, irbesartan, or telmisartan on indices of glucose metabolism in Greek adults with impaired fasting glucose, hypertension, and mixed hyperlipidemia: a 24-week, randomized, open-label, prospective study Clin Ther 32 2010 492 505
17. R.A. Sanchez, L.D. Masnatta, C. Pesiney, P. Fischer, and A.J. Ramirez Telmisartan improves insulin resistance in high renin nonmodulating salt-sensitive hypertensives J Hypertens 26 2008 2393 2398
18. M. Satoh, T. Tabuchi, Y. Minami, Y. Takahashi, T. Itoh, and M. Nakamura Prospective, randomized, single-blind comparison of effects of 6 months of treatment with telmisartan versus enalapril on high-molecular-weight adiponectin concentrations in patients with coronary artery disease Clin Ther 31 2009 2113 2125
19. H. Hasegawa, H. Takano, and H. Narumi Effects of telmisartan and losartan on cardiovascular protection in Japanese hypertensive patients Hypertens Res 34 2011 1179 1184
20. J. Galle, E. Schwedhelm, S. Pinnetti, R.H. Böger, and C. Wanner VIVALDI investigators. Antiproteinuric effects of angiotensin receptor blockers: telmisartan versus valsartan in hypertensive patients with type 2 diabetes mellitus and overt nephropathy Nephrol Dial Transplant 23 2008 3174 3183
21. Y. Yano, S. Hoshide, and J. Ishikawa The differential effects of angiotensin II type 1 receptor blockers on microalbuminuria in relation to low-grade inflammation in metabolic hypertensive patients Am J Hypertens 20 2007 565 572 (Pubitemid 46691290)
22. T. Yokota, T. Osanai, and K. Hanada Effects of telmisartan on markers of ventricular remodeling in patients with acute myocardial infarction: comparison with enalapril Heart Vessels 25 2010 460 468
23. J.M. Nagel, A.B. Tietz, B. Göke, and K.G. Parhofer The effect of telmisartan on glucose and lipid metabolism in nondiabetic, insulin-resistant subjects Metabolism 55 2006 1149 1154 (Pubitemid 44215933)
24. H. Tomiyama, J. Yamada, Y. Koji, K. Shiina, M. Yoshida, and A. Yamashina Effect of telmisartan on forearm postischemic hyperemia and serum asymmetric dimethylarginine levels Am J Hypertens 20 2007 1305 1311 (Pubitemid 350151686)
25. N. Ouchi, S. Kihara, and T. Funahashi Reciprocal association of C-reactive protein with adiponectin in blood stream and adipose tissue Circulation 107 2003 671 674 (Pubitemid 36222590)
26. N. Ouchi, and K. Walsh Adiponectin as an anti-inflammatory factor Clin Chim Acta 380 2007 24 30 (Pubitemid 46498041)
27. H. Takagi, and T. Umemoto Telmisartan increases adiponectin levels: A meta-analysis and meta-regression of randomized head-to-head trials Int J Cardiol Dec 20 2011 [Epub ahead of print]
28. T.W. Kurtz Treating the metabolic syndrome: telmisartan as a peroxisome proliferator-activated receptor-gamma activator Acta Diabetol 42 Suppl. 1 2005 S9 S16
29. N. Maeda, M. Takahashi, and T. Funahashi PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein Diabetes 50 2001 2094 2099 (Pubitemid 33643677)
30. T.P. Combs, J.A. Wagner, and J. Berger Induction of adipocyte complementrelated protein of 30 kilodaltons by PPARgamma agonists: a potential mechanism of insulin sensitization Endocrinology 143 2002 998 1007 (Pubitemid 34164048)
31. G.J. Blake, and P.M. Ridker Novel clinical markers of vascular wall inflammation Circ Res 89 2001 763 771 (Pubitemid 34633846)
32. A. Link, M. Lenz, D. Legner, M. Böhm, and G. Nickenig Telmisartan inhibits beta2-integrin MAC-1 expression in human T-lymphocytes J Hypertens 24 2006 1891 1898 (Pubitemid 44255485)
33. T. Nakamura, T. Inoue, and T. Suzuki Comparison of renal and vascular protective effects between telmisartan and amlodipine in hypertensive patients with chronic kidney disease with mild renal insufficiency Hypertens Res 31 2008 841 850 (Pubitemid 351895027)
34. G. Derosa, A.F. Cicero, and A. D'Angelo Telmisartan and irbesartan therapy in type 2 diabetic patients treated with rosiglitazone: effects on insulin-resistance, leptin and tumor necrosis factor-alpha Hypertens Res 29 2006 849 856 (Pubitemid 46062116)
35. P. Wohl, E. Krusinová, and M. Hill Effect of telmisartan on selected adipokines, insulin sensitivity, and substrate utilization during insulin-stimulated conditions in patients with metabolic syndrome and impaired fasting glucose Eur J Endocrinol 163 2010 573 583