Fertility-sparing surgery for early cervical cancer - Approach to less radical surgery

International Journal of Gynecological Cancer

Volumn 22, Issue 2, 2012, Pages 311-317

  Raju, Shanti Kankipati ^a   Papadopoulos, Andreas John ^b   Montalto, Stephen Attard ^b   Coutts, Michael ^b   Culora, Giuseppe ^a   Kodampur, Malik ^b   Mehra, Gautam ^a   Devaja, Omer ^b  

^a ST THOMAS HOSPITAL   (United Kingdom)

^b MAIDSTONE HOSPITAL   (United Kingdom)

Author keywords

Cervical cancer; Fertility; Pregnancy; Trachelectomy

Indexed keywords

ADULT; ARTICLE; CANCER STAGING; EARLY CANCER; FEMALE; FERTILITY SPARING SURGERY; FOLLOW UP; GYNECOLOGIC SURGERY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; LIVE BIRTH; MAJOR CLINICAL STUDY; MINIMAL RESIDUAL DISEASE; PELVIS LYMPHADENECTOMY; POSTOPERATIVE COMPLICATION; PREGNANCY OUTCOME; PREGNANCY RATE; PRIORITY JOURNAL; RADICAL VAGINAL TRACHELECTOMY; UTERINE CERVIX CANCER;

ADENOCARCINOMA; ADULT; CARCINOMA, ADENOSQUAMOUS; CARCINOMA, SQUAMOUS CELL; COHORT STUDIES; ENGLAND; FEMALE; FERTILITY; HUMANS; HYSTERECTOMY; NEOPLASM STAGING; PREGNANCY; PREGNANCY RATE; PROSPECTIVE STUDIES; TREATMENT OUTCOME; UTERINE CERVICAL NEOPLASMS; YOUNG ADULT;

EID: 84858274205     PISSN: 1048891X     EISSN: 15251438     Source Type: Journal    
DOI: 10.1097/IGC.0b013e3182370f51     Document Type: Article

References (24)

1. Poole J, Patnick J. Profile of Cervical Cancer in England, Incidence, Mortality and Survival. Trent Cancer Registry, the NHS Cervical Screening Programme; 2011.
2. Saraiya M, Ahmed F, Krishnan S, et al. Cervical cancer incidence in a pre vaccine era in United States, 1998-2002. Obstet Gynecol. 2007;109:360-370. (Pubitemid 46197429)
3. Wertheim E. The extended abdominal operation for carcinoma uteri. (Based on 500 operative cases). Translated by Grad H. Am J Obstet Dis Women Child. 1912;66:169-232.
4. Meigs JV. Radical hysterectomy with bilateral pelvic lymph node dissections. Report of 100 cases operated on 5 years or more ago. Am J Obstet Gynecol. 1951;62:854-870.
5. Burghardt E, Holzer E. Diagnosis and treatment of microinvasive carcinoma of the cervix uteri. Obstet Gynecol. 1977;49:641-653. (Pubitemid 8131448)
6. Burghardt E, Giraridi F, Lahousen M, et al. Microinvasive carcinoma of the uterine cervix. Cancer. 1991;67:1037-1045.
7. Dargent D, Brun JL, Roy M, et al. La trachelectomie élargie: uneé alternative á l'hysteérectomie. Radicale dansu traitment des cancers in filtrants. Jobgyn. 1994;2:285-292.
8. Dargent D, Brun JL, Roy M, et al. Pregnancies following radical trachelectomy for invasive cervical cancer. Gynecol Oncol. 1994;52:105.
9. Plante M, Renaud MC, Hoskins IA, et al. Vaginal radical trachelectomy: a valuable fertility-preserving option in the management of early-stage cervical cancer. A series of 50 pregnancies and review of the literature. Gynecol Oncol. 2005;98:3-10. (Pubitemid 40826411)
10. Shepherd JH, Spencer C, Herod J, et al. Radical vaginal trachelectomy as a fertility sparing procedure in women with early stage cervical cancer - cumulative pregnancy rate in a series of 123 women. Brit J Obstet Gynecol. 2006;113:719-724. (Pubitemid 43781704)
11. Abu-Rustum NR, Neubauer N, Sonoda Y, et al. Surgical and pathologic outcomes of fertility sparing radical abdominal trachelectomy for FIGO stage IB1 cervical cancer. Gynecol Oncol. 2008;111:261-264.
12. Frumovitz M, Sun CC, Schmeler KM, et al. Parametrial involvement in radical hysterectomy specimens for women with early-stage cervical cancer. Obstet Gynecol. 2009;114:93-99.
13. Shemeler KM, Frumovitz M, Ramirez PT. Conservative management of early cervical cancer: is there a role for less radical surgery? Gynecol Oncol. 2011;120:321-325.
14. Rob L, Charvat M, Robova H, et al. Less radical fertility-sparing surgery than radical trachelectomy in early cervical cancer. Int J Gynecol Cancer. 2007;17: 304-310. (Pubitemid 46214010)
15. Petignat P, Stan C, Megevand E, et al. Pregnancy after trachelectomy: a high-risk condition of preterm delivery. Report of a case and review of the literature. Gynecol Oncol. 2004;94:575-577. (Pubitemid 39024571)
16. Bernardini M, Barrett J, Seaward G, et al. Pregnancy outcomes in patients after radical trachelectomy. Am J Obstet Gynecol. 2003;189:1378-1382. (Pubitemid 37542176)
17. Fagotti A, Gagliardi ML, Moruzzi C, et al. Excisional cone as fertility sparing treatment in early stage cervical cancer. Fertil Steril. 2011;95:1109-1112.
18. Lanowska M, Morawietz L, Sikora A, et al. Prevalence of lymph nodes in the parametrium of radical vaginal trachelectomy (RVT) specimen. Gynecol Oncol. 2011;121:298-302.
19. Kinney WK, Hodge DO, Egorshin EV, et al. Surgical treatment of patients with stages IB and IIA carcinoma of the cervix and palpably positive pelvic lymph nodes. Gynecol Oncol. 1995;57:145-149.
20. Covens A, Rosen B, Murphy J, et al. How important is removal of the parametrium at surgery for carcinoma of the cervix? Gynecol Oncol. 2002;84:145-149. (Pubitemid 34056481)
21. Stegeman M, Louwen M, van der Velden J, et al. The incidence of parametrial tumor involvement in select patients with early cervix cancer is too low to justify parametrectomy. Gynecol Oncol. 2007;105:475-480. (Pubitemid 46591976)
22. Wright JD, Grigsby PW, Brooks R, et al. Utility of parametrectomy for early stage cervical cancer treated with radical hysterectomy. Cancer. 2007;110:1281-1286. (Pubitemid 47435599)
23. Morice P, Piovesan P, Rey A, et al. Prognostic value of lymphovascular space invasion determined with hematoxylin-eosin staining in early stage cervical carcinoma: results of a multivariate analysis. Ann Oncol. 2003;14:1511-1517. (Pubitemid 37304606)
24. Suri A, Frumovitz M, Milam MR, et al. Preoperative pathologic findings associated with residual disease at radical hysterectomy in women with stage IA2 cervical cancer. Gynecol Oncol. 2009;112:110-113.