Aldosterone inhibits endothelial morphogenesis and angiogenesis through the downregulation of vascular endothelial growth factor receptor-2 expression subsequent to peroxisome proliferator-activated receptor gamma

Journal of Steroid Biochemistry and Molecular Biology

Volumn 129, Issue 3-5, 2012, Pages 145-152

  Fujii, Miki ^a   Inoki, Isao ^a   Saga, Makoto ^a   Morikawa, Norihiro ^a   Arakawa, Ken Ichiro ^a   Inaba, Satoru ^a   Yoshioka, Kazuaki ^b   Konoshita, Tadashi ^a   Miyamori, Isamu ^a  

^a UNIVERSITY OF FUKUI   (Japan)

^b KANAZAWA UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCE   (Japan)

Author keywords

Aldosterone; Angiogenesis; Eplerenone; PPAR gamma; VEGFR 2

Indexed keywords

2 CHLORO 5 NITROBENZANILIDE; ALDOSTERONE; EPLERENONE; MATRIGEL; MINERALOCORTICOID RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TROGLITAZONE; VASCULOTROPIN RECEPTOR 2;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARDIOVASCULAR DISEASE; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IN VIVO STUDY; MORPHOGENESIS; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RECEPTOR DOWN REGULATION; RECEPTOR UPREGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ALDOSTERONE; ALDOSTERONE ANTAGONISTS; ANGIOGENESIS INHIBITORS; ANIMALS; COLLAGEN; DOWN-REGULATION; DRUG COMBINATIONS; ENDOTHELIUM; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; LAMININ; MALE; MICE; MICE, INBRED C57BL; MORPHOGENESIS; NEOVASCULARIZATION, PHYSIOLOGIC; PPAR GAMMA; PROTEOGLYCANS; SPIRONOLACTONE; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

MUS;

EID: 84858221039     PISSN: 09600760     EISSN: 18791220     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2011.12.014     Document Type: Article

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