A Short History of Insect (Neuro)Peptidomics-A Personal Story of the Birth and Youth of an Excellent Model for Studying Peptidome Biology

Peptidomics: Methods and Applications

Volumn , Issue , 2007, Pages 25-54

  Verhaert, Peter D E M ^a,b   Pinkse, Martijn W H ^a,b   Prieto Conaway, Maria C ^c   Kellmann, Markus ^d  

^a KLUYVER CENTRE FOR GENOMICS OF INDUSTRIAL FERMENTATION   (Netherlands)

^b DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

^c Thermo Finnigan   (United States)

^d Thermo Fischer Scientific   (Germany)

Author keywords

Bioassays and nucleic acid hybridization tests; Collision induced dissociation; Retrocerebral complex extracts

Indexed keywords

EID: 84858168972     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470196502.ch2     Document Type: Chapter

References (96)

1. Verhaert P. Onderzoek naar de aanwezigheid van neurophysines en een aantal neuropeptiden bij Periplaneta americana en Locusta migratoria (Insecta) [Master's thesis]. University of Leuven;1983.
2. Predel R, Gaede G. Peptidomics of neurohemal organs from species of the cockroach family Blattidae: how do neuropeptides of closely related species differ? Peptides 2005;26:3-9.
3. Predel R. Peptidergic neurohemal system of an insect: mass spectrometric morphology. J Comp Neurol 2001;436:363-375.
4. Scharrer E, Scharrer B. Secretory cells within the hypothalamus. Res Publ Assoc Nerv Ment Dis 1940;20:170-194.
5. Scharrer B. Peptidergic neurons: Facts and trends. Gen Comp Endocrinol 1978;34: 50-62.
6. Hansen BL, HansenGN, Scharrer B. Immunoreactive material resembling vertebraet neuropeptides in the corpus cardiacum and corpus allatum of the insect Leucophaea maderae. Cell Tissue Res 1982;225:319-329.
7. Verhaert P. Onderzoek naar het voorkomen van stoffen met kenmerken van peptidehormonen van gewervelde dieren bij insekten. Een studie op de Amerikaanse kakkerlak, Periplaneta americana L. [PhD thesis]. University of Leuven;1987.
8. Verhaert P, Marivoet S, Vandesande F, De Loof A. Localization of CRF immunoreactivity in the central nervous system of three vertebrate and one insect species. Cell Tissue Res 1984;238:49-53.
9. Verhaert P, Geysen J, De Loof A, Vandesande F. Immunoreactive material resembling vertebrate neuropeptides and neurophysins in the brain, suboesophageal ganglion, corpus cardiacum and corpus allatum of the dictyopteran Periplaneta americana L. Cell Tissue Res 1984;238:55-59.
10. Verhaert P, De Loof A. Immunocytochemical localization of a methionine-enkephalin-resembling neuropeptide in the central nervous system of the American cockroach, Periplaneta americana L. J Comp Neurol 1985;239:54-61.
11. Verhaert P, Grimmelikhuijzen CJP, De Loof A. Distinct localization of FMRFamide-and bovine pancreatic polypeptide-like material in the brain, retrocerebral complex and suboesophageal ganglion of the cockroach Periplaneta americana L. Brain Res 1985;348:331-338.
12. Verhaert P, DeLoof A. Substances resembling peptides of the vertebrate gonadotropin system occur in the central nervous system of Periplaneta americana L. Immunocytological and some biological evidence. Insect Biochem 1986;16:191-197.
13. Verhaert PDEM, Downer RGH, Huybrechts R, De Loof A. A substance resembling somatomedin C in the American cockroach. Regul Pept 1989;25:99-110.
14. De Loof A, Verhaert P, Cardoen J. Growth hormone, prolactin and other immmunoreactive peptide hormones in the insect Periplaneta americana L. Cell Differe 1985;16:78S. Abstract 10th International Symposium on Developmental Biology.
15. Verhaert P, De Loof A. Immunoreactive materials resembling vertebrate peptides involved in steroid hormone synthesis are present in the central nervous system of Periplaneta americana L. In: Abstract VIIth Ecdysone Workshop. Abstract volume; 1985.
16. Verhaert P, Schols D, Vanden Broeck J, De Loof A. Brain and gastrointestinal peptides of the vertebrate-type in the American cockroach, Periplaneta americana L. Three complementary approaches. In: Abstract 2nd International Conference on Insect Neurochemistry and Neurophysiology. Abstract volume;1986.
17. Verhaert P, Auwers A, De Vos A, Schoofs L, Huybrechts L, De Loof A, Vaudry H, Jégou S. Periplaneta americana L. (Insecta, Blattidae) nervous system contains various substances with vertebrate proopiomelanocortin-derived peptide-like properties. Gen Comp. Endocrinol 1987;66:46. (Abstract 13th Conference of European Comparative Endocrinologists).
18. Zhu W, Verhaert P, Shaw C, Maule A, De Loof A, Vaudry H. NPFimmunolocalization in the cockroaches and locusts. Comparison of antisera to beetle, tapeworm and pig NPY/NPF-type peptides. Ann NY Acad Sci 1997;893:625-627.
19. Verhaert P, Fónagy A, Walgraeve H, De Loof A. Occurrence of human gonadotropic hormone-like immunoreactivity in the brain and retrocerebral complex of the American cockroach during post-embryonic development. Int J Invert Reprod Dev 1989;18:131. (Abstract IXth Ecdysone Workshop).
20. Verhaert P, Yanaihara N, De Loof A. Immunohistochemical investigation of a peptide histidine-isoleucine-like substance in brain and gut of the insect, Periplaneta americana L. Digestion 1990;46(S1):117. (Abstract 8th Int. Symposium on Gastrointestinal Hormones).
21. Verhaert P, Yanaihara N, De Loof A. Immunocytochemical localization of gastrinreleasing peptide (GRP)/bombesin (BB)-like material in the American cockroach, Periplaneta americana L. Digestion 1990;46(S1):117-118. (Abstract 8th International Symposium on Gastrointestinal Hormones).
22. Verhaert PDEM, Fonagy A, Van Ranst L, Lauweryns JM, De Loof A. Are (immuno) histochemical markers of the vertebrate diffuse neuroendocrine system applicable to the insect brain as well? A study on the American cockroach, Periplaneta americana L. Gen Comp Endocrinol 1990;82:322. (Abstract 15th International Conference of European Comparative Endocrinologists).
23. Verhaert PDEM, Schooneveld H, De Loof A. Comparative adipokinetic hormoneimmunohistochemistry in cockroach retrocerebral complexes and brains reveals considerable species differences. Gen Comp Endocrinol 1990;82:327. (Abstract 15th International Conference of European Comparative Endocrinologists).
24. Verhaert PDEM, Hansen BL, Hansen GN, De Loof A. Cockroach insulin-like growth factor I-and other insulin-related material(s), an update. In Abstract 2nd Internationl Symposium on Insulin-like Growth Factors/Somatomedins. Abstract volume;1991. p 46.
25. Verhaert PD, Shaw C, Maule AG, Halton DW, De Loof AJ. Presence and distribution of neuropeptide F-like immunoreactivity in an insect. Regul Pept 1992;39:277. (Abstract 12th National Scientific Meeting of the Bayliss & Starling Society).
26. Verhaert PD, Ma MC, De Loof AJ. Antibodies to moth pheromone biosynthesis activating neurohormone detect homologous neurons in cockroaches. Regul Pept 1992;39:278. (Abstract 12th National Scientific Meeting of the Bayliss & Starling Society).
27. Verhaert PD, Shaw C, Maule AG, Halton DW, De Loof AJ. Neuropeptide F-like immunoreactivity in insects, occurrence, distribution and partial characterization. In: Abstract 16th Conference of European Comparative Endocrinologists. Abstract volume;1992. p 202.
28. Verhaert P, Van de Voorde A, Shaw C, Maule A, Halton D, De Loof A. Localization and partial characterization of a neuropeptide F-like substance in two insect species. In: Abstract 4th International Conference on Insect Neurochemistry and Neurophysiology. Abstract volume;1993.
29. Verhaert P, Callaerts P, Vande Voorde A, Shaw C, Maule A, Halton D, De Loof A. Une substance apparentée au neuropeptide F chez deux diptères (Insectes) différents, distribution et caractérisation partielle. Ann Endocrinol 1993;54:34. Abstract XXII Colloque de la Société de Neuroendocrinologie Expérimentale.
30. Verhaert P, Smart D, Shaw C, Maule A, Halton D, De Loof A. Distribution immunohistochimique et purification de substances reconnues par des anticorps anti-leucokinine V et anti-leucopyrokinine dans le système neuroendocrinien de l'insecte Periplaneta americana L. Ann Endocrinol 1993;54:34. (Abstract XXII Colloque de la Société de Neuroendocrinologie Expérimentale).
31. Verhaert P, Depoortere I, Peeters T, De Loof A. Vertebrate gastrointestinal hormone-immunoreactivity in invertebrates. Phylogenetically significant findings or "accidental" cross-reactions? Insect motilin-like material, an example. Acta Gastroenterol Bel 1993;56:B17. (Abstract Vth Belgian Week of Gastroenterology).
32. Shaw C, McMurray G, Verhaert P, Maule AG, Halton DW. Distribution and characterization of neuromedin U (NMU) immunoreactive peptides in flatworms and insects. In: Abstract 12th International Symposium on Neurosecretion. Abstract volume;1995.27.
33. Zhu W, Verhaert P, Shaw C, Maule A, Vaudry H. Specific immunolocalization of NPF-like material in 2 insect species using antisera to beetle, tapeworm and mammalian neuropeptides of the NPY/NPF superfamily. Anna Endocrinol 1996;57: P106. (Abstract 18th Conference of European Comparative Endocrinologists, "From molecular to integrative biology").
34. Verhaert P, De Loof A. Insect neuropeptides, an immunological approach. Belg J Zool 1990;120(Suppl. 1):64-65.
35. Verhaert P, De Loof A. Heterologous immunohistochemistry and its use in comparative (neuro)endocrinology. Possibilities and drawbacks. In: Abstract First Congress of Histotechnology (ESH), Abstract volume;1991. p 63-64.
36. Verhaert P, Van Mellaert H, Swinnen K, De Loof A. Vertebrate somatotropin-like peptides in insects. In:Slavkin HC, editor. Progress in Developmental Biology, Part A Alan R. Liss, Inc; 1986. p 359-364.
37. Verhaert P, Huybrechts R, Schols D, Vanden Broeck J, De Loof A, Vandesande F. Characterization of vertebrate peptide hormone-like materials in the American cockroach, different methods employed to investigate these substances. In: Borkovec AB, Gelman DB, editors. Insect Neurochemistry and Neurophysiology-1986. Humana Press; 1986. p 229-233.
38. De Loof A, Verhaert P, Schoofs L, Huybrechts R, Frankenne F, Hennen G, Vaudry H, Jégou S. Vertebrate-type hormones in insects. In: Sehnal F, Zabza A, Denlinger DL, editors. Endocrinological Frontiers in Physiological Insect Ecology. Wroclaw Technical University Press; 1988. p 813-831
39. Verhaert P, Ma M, De Loof A. Immunochemistry and comparative insect (neuro) endocrinology. Prog Clin Biol Res 1990;342:315-322.
40. Verhaert P, De Loof A. Substance P-like immunoreactivity in the central nervous system of the blattarian insect Periplaneta americana L. revealed by a monoclonal antibody. Histochemistry 1985;83:501-507.
41. Verhaert P, De Loof A. Human luteinizing hormone-like material in the neurosecretory system of Periplaneta americana, a histochemical study with monoclonal antibodies. J Insect Physiol 1988;34:577-583.
42. Verhaert P, De Loof A. Monoclonal antibody immunohistochemistry in the American cockroach identifies a novel neuropeptidergic system similar to, but distinct from this insect's (FM)RFamide-like system. Cell Tissue Res 1993;271:209-215.
43. Verhaert P, Walgraeve H, Downer R, De Loof A. Monoclonal antibodies, a potential tool to characterize neuropeptides in Periplaneta americana. In: Proceedings of the XVIII International Congress of Entomology 1988. p 145. (Abstract XVIII International Congress of Entomology).
44. Verhaert PDEM, Song Q, Ma MC, De Loof A. A fly brain monoclonal antibody binds a neurochemical from insects to mammals. Gen Comp Endocrinol 1990;82:325. (Abstract 15th Int. Conference of European Comparative Endocrinologists).
45. Verhaert PDEM, Schooneveld H, De Loof A. A monoclonal antibody to coleopteran corpus cardiacum extracts reveals a novel neuronal system in the cerebral neurohormonal complex of the cockroach. Comparison with the FMRFamide/BPP-like neuropeptidergic system. Gen Comp Endocrinol 1990;82:326. (Abstract 15th Int. Conference of European Comparative Endocrinologists).
46. Verhaert P, Ma M, De Loof A. Comparative (neuro)endocrinology (insects-vertebrates) by means of heterologous immunocytochemistry. In: Abstract XIth Symposium on Comparative Endocrinology. Abstract volume; 1989. p L-101.
47. Milton GWA, Verhaert PDEM, Downer RGH. Immunofluorescent localization of dopamine-like and leucine-enkephalin-like neurons in the supra-oesophageal ganglia of the American cockroach, Periplaneta americana. Tissue Cell 1991;23: 331-340.
48. Verhaert P, McMurry G, Shaw C, Halton D, Johnston C, De Loof A. Utilisation d'auto-anticorps humains pour l'immunohistochimie du récepteur de l'acétylchotylcholine dans le cerveau de la blatte Periplaneta americana L. Ann Endocrinol 1993;54:33. (Abstract XXII Colloque de la Société de Neuroendocrinologie Expérimentale).
49. Schols D, Verhaert P, Huybrechts R, Vaudry H, Jégou S, De Loof A. Immunocytochemical demonstration of proopiomelanocortin-and other opioidrelated substances and a CRF-like peptide in the gut of the American cockroach, Periplaneta americana L. Histochemistry 1987;86:345-351.
50. Verhaert P, Cardoen J, Vanden Broeck J, De Loof A, Belayew A, Lecomte C, Martial J. Vertebrate cDNA's to peptide hormones hybridize to insect RNA dot blots. Arch Int Physiol Biochim 1985;93:B116-B117.
51. Verhaert P, Vanden Broeck J, De Loof A. Recombinant DNA technology offers novel prospects for the study of vertebrate-type peptides in invertebrates. Bull Soc Zool France 1986;111:5-6. (Abstract International Symposium on Invertebrate Peptides and Amines).
52. Verhaert P, De Loof A. Vertebrate-type peptides in invertebrates. Different approaches. Bull Soc Zool France 1986;111:6-7. (Abstract International Symposium on Invertebrate Peptides and Amines).
53. De Loof A, Huybrechts R, Verhaert P. Vertebrate-peptide hormone like materials in arthropods: identification methods and functions. Bull Serb Acad Sci Arts 1987;29:25-35.
54. Walgraeve HR, Verhaert PD, Downer RG. Phosphatidyl inositol metabolism in the brain of the American cockroach. In: Abstract 3rd International Conference on Insect Neurochemistry and Neurophysiology. Abstract volume; 1989.
55. Verhaert P, Walgraeve H, Downer R. Metabolism of inositolphosphates in the cerebral ganglia of the American cockroach, Periplaneta americana L. In: Borkovec AB, Masler EP, editors. Insect Neurochemistry and Neurophysiology-1989 Humana Press; 1990. p 275-279
56. Verhaert PDEM, Walgraeve HRMA, Downer RGH. Histochemical demonstration of endogenous alkaline phosphatase(s) in the brain of insects-correlation with the distribution of biogenic amines. Gen Comp Endocrinol 1990;82:324. (Abstract 15th International Conference of European Comparative Endo-crinologists).
57. Verhaert PDEM, Walgraeve HRMA, Downer RGH. Alkaline phosphatase activity in the brain of the American cockroach, Periplaneta americana L. Histochem J 1990;2:628-635.
58. Verhaert P, Maule A, Shaw C, Halton D, Thim L, De Loof A. Purification and partial characterization of neuropeptide F-like material from the neuroendocrine system of an insect. In:Borkovec AB, Loeb MJ, editors. Insect Neurochemistry and Neurophysiology-1993. CRC Press Inc; 1993. p 311-314
59. Verhaert P, Schoeters E, De Loof A. Scanning electron microscopy of insect corpora cardiaca, observation of actual neurosecretion? In: Abstract 1st Benelux Congress of Zoology. Abstract volume;1994. p 93.
60. Verhaert PDEM, De Loof AJ. Neurosecretion from an unprecedented viewpoint, scanning electron microscopy of the outer surface of an active neurohaemal area, the insect corpus cardiacum. In: Abstract 12th International Symposium on Neurosecretion. Abstract volume;1995. p 14.
61. Verhaert PD, De Loof AJ. Scanning electron microscopy of an active neurohaemal area, the cockroach (Periplaneta americana) corpora cardiaca, looking at neurosecretion from an unprecedented viewpoint. In: Krisch B, Mentlein R, editors. The Peptidergic Neuron. Birkhäuser Verlag; 1996.73-79.
62. Verhaert P, De Loof A. Direct analysis of the peptide content of neuroendocrine tissue by MALDI-TOF mass spectrometry. Regul Peptides 1996;64:198. (Abstract 11th Intetnational Symposium on Regulatory Peptides).
63. Verhaert P, De Loof A. Direct neuropeptide profiling of the insect corpus cardiacum using MALDI mass spectrometry. Ann Endocrinol 1996;57:C03. (Abstract 18th Conference of European Comparative Endocrinologists, "From molecular to integrative biology").
64. Verhaert P, De Loof A. MALDI-TOF-MS for direct neuropeptide profiling of the insect corpus cardiacum. Ann NY Acad Sci 1997;893:343-345.
65. Verhaert PD, Critchley G, De Loof AJ, Vandesande F. Post-source decay analysis of alkali-adducts of peptides desorbed directly from biological tissue. In: Abstract 14th International Mass Spectrometry Conference. Abstract volume;1997.
66. Verhaert P. Neuropeptide analysis by mass spectrometry. Q-TOF, the first experience. In: Abstract Micromass Symposium "What's new in Mass Spectrometry?". Abstract volume;1996.
67. Verhaert P, Bordoli R, Hoyes J, Critchley G, Vandesande F, De Loof A. Analysis of un-separated mixtures of neuropeptides by mass spectrometry, From MALDI-TOF to Q-TOF. In: Gecombineerde chromatografische en massaspectrometrische technieken. 1996. p 13.(Abstract Symposium Nederlandse Vereniging voor Massaspectrometrie).
68. Verhaert P, Critchley G, Brown J, Vandesande F, De Loof A. PSD analysis of sodium-and potassium-adducts of selected peptide ions desorbed directly from biological tissues. In: Karjalainen EJ, Hesso AE, Jalonen JE, Karjalainen UP, editors. Advances in Mass Spectrometry. 1998. p 14.
69. Verhaert P. Nanoflow Q-TOF MS (-MS), a new tool in neuroscience? In:Abstract Micromass Users Meeting. Abstract volume;1997.
70. Verhaert P, De Loof A, Vandesande F, Bordoli R, Hoyes J. Direct sequencing of unseparated neuropeptides from neuronal tissue of single insects using Q-TOF MS/MS. In:Abstract 45th ASMS Conference on Mass Spectrometry and Allied Topics. Abstract volume;1997.
71. Verhaert P, De Loof A, Morris M, Bordoli B. Fast identification of biological agents using nanoflowelectrospray time of flight (tandem)mass spectrometry. In: Proceedings First Joint Services Workshop on Biological Mass Spectrometry. 1997. p 83-89.
72. Verhaert P, Vandesande F, De Loof A. Direct sequencing of unseparated neuropeptides by tandem-nano-Q-TOF mass spectrometry. In: Abstract 2nd Annual BSMS Meeting on Mass Spectrometry in Pharmaceutical Analysis. Abstract volume;1997.
73. Verhaert P, Vandesande F, De Loof A. Biology and mass spectrometry, a perfect match. In: Abstract 4th Benelux Congress of Zoology. Abstract volume;1997.
74. Verhaert P, Koellisch G, Shaw C, Raymackers J, Van de Voorde A. State of the art TOF MS in neurobiology. MALDI and nano-ESI-a perfect marriage. In:MS in Proteomics and Drug Discovery. An International Seminar on the Enabling Role of MS;1998. p 15.
75. Verhaert P, De Loof A. The use of time-of-flight mass spectrometry in the study of insect neurohormones-an overview. In: The VIth European Congress of Entomology, Book of Abstracts;1998. p 99.
76. Verhaert P. The introduction of state-of-the-art TOF mass sepctrometry in neuropeptide research, a promising development. In: Abstract 3rd Annual BSMS Meeting on TOF Mass Spectrometry. Abstract volume;1998.
77. Verhaert P, Vandesande F, De Loof A. Automated analysis of the peptidome. No longer science fiction. In: MS in Proteomics and Drug Discovery. 2nd International Seminar on the Enabling Role of MS;1999.
78. Verhaert PDEM, Peeters TL. State-of-the-art time-of-flight mass spectrometry, promising technology for gastrointestinal peptide hormone analysis. Acta Gastroenterol Bel 2000;63:B6.
79. Verhaert P. "in vivo" neuropeptide sequencing by nanospray QSTAR pulsar and MALDI quadrupole orthogonal TOF technology. In: Abstract Sciex Users Meeting. Abstract volume;2000.
80. Verhaert PD, de Vries MP, Köllisch GV, Hoffmann KH, Uttenweiler-Joseph S, Loboda A, Ens W, Standing KG. Direct tissue de novo neuropeptide sequencing using nanoESI and MALDI quadrupole-oaTOF hybrid MS/MS instruments. In: Abstract 49th ASMS Conference on Mass Spectrometry and Allied Topics. Abstract volume;2001.
81. Verhaert P, Uttenweiler-Joseph S, de Vries M, Loboda A, Ens W, Standing KG. Matrix-assisted laser desorption/ionization quadrupole time-offlight mass spectrometry, an elegant tool for peptidomics. Proteomics 2001;1: 118-131.
82. Verhaert PD, Clerens SP, Arckens LH, De Bock I, de Vries MP, van der Locht SJ, Bos ES. In situ orthogonal MALDI MS and MS/MS decoding the language of life. In: Abstract 50th ASMS Conference on Mass Spectrometry and Allied Topics. Abstract volume;2002.
83. Verhaert P, Kellmann M, Le Yondre N, Ziegert T, Clerens S, Arckens L, de Pauw E. Direct tissue peptidome analysis, from (biomarker) profiling to imaging. In: Abstract SCM2 Amsterdam. Abstract volume;2005.
84. Verhaert P, Kellmann M, LeYondre N, Van de Plas B, Clertens S. Biology and neuropeptidomics, the cockroach neuroendocrine gland as a model system. In: Abstract Swedish Proteomic Society Symposium. Abstract volume; 2005.
85. Verhaert PD, Kellmann M, Clerens S, Van de Plas B, Arckens L, Schulz-Knappe P. Digging deeper in the (direct tissue) proteome segment of natural peptides. In: Abstract 53rd ASMS Conference. Abstract volume;2005.
86. Verhaert P, Wens J, Jouk P, LeYondre N, Kellmann M, Schulz-Knappe P, Thevelein J. Biology and (Neuro)Peptidomics, the insect 'pituitary gland' as a model system. Abstract DRC-LSTBSDL Symposium. Abstract volume;2005.
87. Schwarz G, Verhaert P, Langridge J, Vissers H. Accurate mass mapping and sequencing of corpus cardiacum neuropeptides by means of nanoscale LC-MALDITOF MS/MS. Waters Application Note;2006.
88. Verhaert PD, Schwarz G, Kroon AR, Langridge JL, Vissers JPC. Accurate mass mapping and sequencing of corpus cardiacum neuropeptides by means of LCMALDI-oaTOF MS/MS and UPLC-oaTOF MS. In: Proceedings of the 54th ASMS Conference on Mass Spectrometry and Allied Topics;2006. Available at http://www.asms.org/asms06pdf/A063532.pdf.
89. McDonnell LA, Piersma SR, Altelaar AFM, Mize TH, Luxembourg SL, Verhaert PD, van Minnen J, Heeren RM. Subcellular imaging mass spectrometry of brain tissue. J Mass Spectrom 2005;40:160-168.
90. Verhaert P. Mass spectrometry imaging (MSI) and peptidomics. A perfect match?(Abstract 2006 Lorne Symposium on Proteomics). Abstract volume; 2006.
91. Verhaert PD, Prieto Conaway MC, Pekar TM, Miller K. Neuropeptide imaging on an LTQ with vMALDI source. The complete 'all-in-one' peptidome analysis. Int J Mass Spectrom 2007;260:177-184.
92. Verhaert P, Pinkse M, Walgraeve H, Prieto M. Mass spectrometry imaging of (insect) neuronal tissue. In:Caprioli R, Heeren RMA, Stoeckli M, editors. Imaging Mass Spectrometry. (19th ASMS Sanibel Conference on Mass Spectrometry) 2007.
93. Schulz-Knappe P, Selle H, Zucht H-D, Schraeder M. General outline of peptidomics technologies. In: Gaenshirt D, Harms F, Rohmann S, Schulz-Knappe P, editors. Peptidomics in Drug Development. Edito Canter Verlag; Aulendorf (Germany): 2005;29-32.
94. Marshall AG, Wang TCL, Ricca TL. Tailored excitation for Fourier transform ion cyclotron mass spectrometry. J Am Chem Soc 1985;107:7893-7897.
95. Garrett TJ, Yost RA. Analysis of intact tissue by intermediate-pressure MALDI on a linear ion trap mass spectrometer. Anal Chem 2006;78:2465-2469.
96. Fälth M, Sköld K, Norrman M, Svensson M, FenyöD, Andrén PE. SwePep, a database designed for endogenous peptides and mass spectrometry. Mol Cell Proteomics 2006;5:998-1005.