Overcoming instability and low solubility of new cytostatic compounds: A comparison of two approaches

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 80, Issue 3, 2012, Pages 657-662

  Cagno, Massimiliano Di ^a   Stein, Paul C ^a   Styskala, Jakub ^b   Hlaváč, Jan ^b   Skalko Basnet, Natasa ^c   Bauer Brandl, Annette ^a  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^b PALACKÝ UNIVERSITY   (Czech Republic)

^c UNIVERSITY OF TROMSØ   (Norway)

Author keywords

1H NMR; Chemical stability; Cyclodextrins; Quinolinone derivatives; Solubilization; TPGS micelles

Indexed keywords

ANTIOXIDANT; BETA CYCLODEXTRIN DERIVATIVE; CYCLODEXTRIN; CYTOSTATIC AGENT;

ANTIOXIDANT ACTIVITY; ARTICLE; COMPLEX FORMATION; DRUG BIOAVAILABILITY; DRUG SOLUBILITY; DRUG STABILITY; DRUG STRUCTURE; FREEZE DRYING; INTERMETHOD COMPARISON; MICELLE; PHYSICAL CHEMISTRY;

ANTIOXIDANTS; BETA-CYCLODEXTRINS; BIOLOGICAL AVAILABILITY; CHEMISTRY, PHARMACEUTICAL; CYTOSTATIC AGENTS; DRUG STABILITY; FREEZE DRYING; HYDROXYQUINOLINES; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MICELLES; PARTICLE SIZE; PHOTOELECTRON SPECTROSCOPY; POLYETHYLENE GLYCOLS; SOLUBILITY; SURFACE-ACTIVE AGENTS; VITAMIN E; WATER;

EID: 84858157244     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2011.11.016     Document Type: Article

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