Amorphous amphiphilic P(3HV-co-4HB)-b-mPEG block copolymer synthesized from bacterial copolyester via melt transesterification: Nanoparticle preparation, cisplatin-loading for cancer therapy and in vitro evaluation

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 80, Issue 3, 2012, Pages 518-527

  Shah, Mohsin ^a   Ullah, Najeeb ^a   Choi, Mun Hwan ^a   Kim, Myeong Ok ^a   Yoon, Sung Chul ^a  

^a Gyeongsang National University   (South Korea)

Author keywords

Amorphous block copolymers; Apoptosis; Cisplatin; Core shell NPs; Slow release

Indexed keywords

AMPHOPHILE; CISPLATIN; COPOLYMER; ETHYLENE GLYCOL; HYDROXYBUTYRIC ACID; NANOPARTICLE; POLY(3 HYDROXYVALERATE CO 4 HYDROXYBUTYRATE); UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER THERAPY; CYTOTOXICITY; EMULSION; EVAPORATION; HUMAN; HUMAN CELL; HYDROPHILICITY; HYDROPHOBICITY; IN VITRO STUDY; MELTING POINT; PARTICLE SIZE; SUSTAINED DRUG RELEASE; TRANSESTERIFICATION; TRANSMISSION ELECTRON MICROSCOPY; TUMOR CELL; TUMOR GROWTH; ZETA POTENTIAL;

ANTINEOPLASTIC AGENTS; APOPTOSIS; BIOLOGICAL AVAILABILITY; CELL LINE, TUMOR; CELL PROLIFERATION; CISPLATIN; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; NANOPARTICLES; NEOPLASMS; PARTICLE SIZE; POLYESTERS; POLYETHYLENE GLYCOLS; SURFACE-ACTIVE AGENTS;

EID: 84858156521     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2011.11.014     Document Type: Article

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