Embryonated chicken eggs as alternative infection model for pathogenic fungi

Methods in Molecular Biology

Volumn 845, Issue , 2012, Pages 487-496

  Jacobsen, Ilse D ^a   Große, Katharina ^a   Hube, Bernhard ^a,b  

^a HANS KNÖLL INSTITUTE   (Germany)

^b FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

Alternative infection model; Aspergillus fumigatus; Candida albicans; Embryonated eggs; Virulence

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ASPERGILLUS FUMIGATUS; CANDIDA ALBICANS; CHICKEN; CHORIOALLANTOIS; NONHUMAN; ZYGOTE; ANIMAL; ARTICLE; CHICK EMBRYO; DISEASE MODEL; HOST PATHOGEN INTERACTION; MICROBIOLOGY; PATHOGENICITY;

ANIMALS; ASPERGILLUS FUMIGATUS; CANDIDA ALBICANS; CHICK EMBRYO; DISEASE MODELS, ANIMAL; HOST-PATHOGEN INTERACTIONS;

ASPERGILLUS FUMIGATUS; CANDIDA ALBICANS; FUNGI;

EID: 84858145625     PISSN: 10643745     EISSN: 19406029     Source Type: Book Series    
DOI: 10.1007/978-1-61779-539-8_34     Document Type: Chapter

References (6)

1. Clemons, K. V., and D. A. Stevens (2005). The contribution of animal models of aspergillosis to understanding pathogenesis, therapy and virulence. Med Mycol 43 Suppl 1:S101110.
2. Adam, R., S. Mussa, D. Lindemann, T. A. Oelschlaeger, M. Deadman, D. J. Ferguson, R. Moxon, and H. Schroten (2002). The avian chorioallantoic membrane in ovo--a useful model for bacterial invasion assays. Int J Med Microbiol 292:267–275.
3. Townsend, M. K., N. J. Carr, J. G. Iyer, S. M. Horne, P. S. Gibbs, and B. M. Pruss (2008). Pleiotropic phenotypes of a Yersinia enterocolit-ica flhD mutant include reduced lethality in a chicken embryo model. BMC Microbiol 8:12.
4. Gow, N. A., Y. Knox, C. A. Munro, and W. D. Thompson (2003). Infection of chick chorioallantoic membrane (CAM) as a model for invasive hyphal growth and pathogenesis of Candida albicans. Med Mycol 41:331–338.
5. Härtl, A., H. G. Hillesheim, W. Kunkel, and E. J. Schrinner (1995). [The Candida infected hen’s egg. An alternative test system for systemic anticandida activity]. Arzneimittelforschung 45:926–928.
6. Jacobsen, I. D., K. Grosse, S. Slesiona, B. Hube, A. Berndt, and M. Brock (2010). Embryonated eggs as an alternative infection model to investigate Aspergillus fumigatus virulence. Infect Immun. 78(7):2995–3006.